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The NAS Trace Visualizer (NTV)

NTV is a tool used to visualize execution traces from message passing systems. It is designed to be ported easily to different trace formats. The first version of NTV uses trace files produced using AIMS Version 2.2. Versions for the native traces from the IBM SP2 and Intel Paragon are nearing completion. A distinctive characteristic of NTV is that it uses static displays rather then time varying displays. This, in combination with mouse controlled zooming, gives the user the ability to get a global view of the execution and a focused view of details. The principal display is a time line display that shows a color coded time line for each processor. The color coding shows the processor status. Messages between processors are indicated by lines connecting the processors involved in the communications. Controls for these message edges let the user show all messages, no messages, or only message between specified sets of processors. Summary (profiling) displays are also produced. These are of two types. One allocates information by processor, e.g., the time the processor was blocked sending, and the other allocates information by function, e.g., the time a function was blocked sending.

Lopez, Louis↗

Conceptual Design and Cost Estimate of a Subsonic NASA Testbed Vehicle (NTV) for Aeronautics Research

A conceptual design and cost estimate for a subsonic flight research vehicle designed to support NASA's Environmentally Responsible Aviation (ERA) project goals is presented. To investigate the technical and economic feasibility of modifying an existing aircraft, a highly modified Boeing 717 was developed for maturation of technologies supporting the three ERA project goals of reduced fuel burn, noise, and emissions. This modified 717 utilizes midfuselage mounted modern high bypass ratio engines in conjunction with engine exhaust shielding structures to provide a low noise testbed. The testbed also integrates a natural laminar flow wing section and active flow control for the vertical tail. An eight year program plan was created to incrementally modify and test the vehicle, enabling the suite of technology benefits to be isolated and quantified. Based on the conceptual design and programmatic plan for this testbed vehicle, a full cost estimate of $526M was developed, representing then-year dollars at a 50% confidence level.

Nickol, Craig L.↗

New and Improved T-wave Morphology Parameters to Differentiate Healthy Individuals from those with Cardiomyopathy and Coronary Artery Disease

We investigated the ability of several known as well as new ECG repolarization parameters to differentiate healthy individuals from patients with obstructive coronary artery disease (CAD) and cardiomyopathy (CM). Advanced high-fidelity 12-lead ECG tests (approx. 5-min supine) were first performed on a "training set" of 99 individuals: 33 with ischemic or dilated CM and low ejection fraction (EF less than 40%); 33 with catheterization-proven obstructive CAD but normal EF; and 33 age-/gender-matched healthy controls. The following multiple parameters of T-wave morphology (TWM) were derived via signal averaging and singular value decomposition (SVD, which yields 8 eigenvalues, rho(sub 1) greater than rho(sub 2)...greater than rho(sub 8) and studied for their retrospective accuracy in detecting underlying disease: 1) Principal component analysis ratio of the T wave (T-PCA) = 100*rho(sub 2)/rho(sub 1); 2) Relative T-wave residuum (rTWR) = 100* SIGMA (rho(sub 4)(sup 2) +...+ rho(sub 8)(sup 2)); 3) Modified complexity ratio of the T wave (T-mCR) = 100*SIGMA(rho(sub 3)(sup 2) +...+rho(sb 8) (sup 2)); and 4) Normalized 3-dimensional volume of the T wave (nTV) = 100*(rho(sub 2)*rho(sub 3)/rho(sub 1)(sup 2). All TWM parameters significantly differentiated CAD from controls (p less than 0.0001), and also CM from controls (p less than 0.0001). Retrospective areas under the ROC curve were 0.77, 0.81, 0.82, and 0.83 (CAD vs. controls) and 0.93, 0.89, 0.95 and 0.96 (CM vs. controls) for T-PCA, rTWR, T-mCR and nTV respectively. The newer TWM parameters (T-mCR and nTV) thus outperformed the more established parameters (T-PCA and rTWR), presumably by putting a greater emphasis on the third T-wave eigenvalue, which in most healthy subjects has little energy compared to the first two eigenvalues. Subsequent prospective analyses have also yielded similar results, such that we conclude that diagnostic differentiation of pathology from non-pathology may be especially aided by detecting the transference of energy from the first and second T-wave eigenvalues into the third T-wave eigenvalue.

Greco, E. C.↗

Passivity In Analysis Of Robustness Of A Control System

Robustness margin (measure of degree of passivity) defined. Paper presents new approach to analysis of stability of multivariable feedforward-and-feedback control system consisting of exponentially stable linear time-invariant (LTI) feedforward subsystem and nonlinear time-varying (NTV) or dynamic feedback subsystem. New method based on notion of passivity, quantified by robustness margin. Margin provides bound on magnitudes of perturbations, below which perturbations will not make system unstable.

Wen, John Ting-Yung↗

Multi-channel System for Beat to Beat QT Interval Variability and its Use in Screening for Coronary Artery Disease and Cardiomyopathy

We investigated the ability of beat-to-beat QT interval variability (QTV) and related parameters to differentiate healthy individuals from patients with obstructive coronary artery disease (CAD) and cardiomyopathy (CM). For this purpose we developed a PC-based ECG software program that in real time, acquires, analyzes and displays QTV in each of the eight independent channels that constitute the 12-lead conventional ECG. The system also analyzes and displays the QTV from QT interval signals that are derived from multiple channels and from singular value decomposition (SVD) to substantially reduce the effect of noise and other artifacts on the QTV results. It also provides other useful SVD-related parameters such as the normalized 3-dimensional volume of the T wave (nTV) = 100*(rho(sub 2)*rho(sub 3)rho(sub 1^2). Advanced high-fidelity 12-lead ECG tests (approx. 5-min supine) were first performed on a "training set" of 99 individuals: 33 with ischemic or dilated CM and low ejection fraction (EF less than 40%); 33 with catheterization-proven obstructive CAD but normal EF; and 33 age-/gender-matched healthy controls. All QTV parameters that were studied for their accuracy in detecting CM and CAD significantly differentiated both CM and CAD from controls (p less than 0.0001). Retrospective areas under the ROC curve (AUC) of SDNN-QTV, rmsSD-QTV, and QTV Index (QTVI) for CM vs. controls in the lead V5 were 0.85, 0.90, and 0.99, respectively, and those for CAD vs. controls in the lead II were 0.82, 0.82, and 0.89. Other advanced ECG parameters, such as HFQRS RAZ score, LF Lomb of RRV or QRS-T angle, differentiated both CM and CAD from controls less significantly, with the respective AUC values of 0.89, 0.88 and 0.98 for CM vs. controls, and 0.73, 0.71 and 0.80 for CAD vs. controls. QTV parameters (especially QTVI, which is QTV as indexed to RRV) were, diagnostically speaking, amongst the best performing of the advanced ECG techniques studied thus far.

Starc, V.↗