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Results for “Pelleting”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 19 records

Novel method to assess gastric emptying in humans: the Pellet Gastric Emptying Test

To further validate the Pellet Gastric Emptying Test (PGET) as a marker of gastric emptying, a randomized, four-way crossover study was conducted with 12 healthy subjects. The study consisted of oral co-administration of enteric coated caffeine (CAFF) and acetaminophen (APAP) pellets in four treatment phases: Same Size (100 kcal), Fasted, Small Liquid Meal (100 kcal), and Standard Meal (847 kcal). The time of first appearance of measurable drug marker in plasma, t(initial), was taken as the emptying time for the markers. Co-administration of same size enteric coated pellets of CAFF and APAP (0.7 mm in diameter) revealed no statistically significant differences in t(initial) values indicating that emptying was dependent only on size and not on chemical make-up of the pellets. Co-administration of different size pellets indicated that the smaller 0.7-mm diameter (CAFF) pellets were emptied and absorbed significantly earlier than the larger 3.6-mm diameter (APAP) pellets with both the Small Liquid Meal (by 35 min) and the Standard Meal (by 33 min) (P<0.05). The differences in emptying of the pellets were not significant in the Fasted Phase. The results suggest that the pellet gastric emptying test could prove useful in monitoring changes in transit times in the fasted and fed states and their impact on drug absorption.

NASA Discipline Regulatory Physiology↗

A centrifuge CO2 pellet cleaning system

An advanced turbine/CO2 pellet accelerator is being evaluated as a depaint technology at Oak Ridge National Laboratory (ORNL). The program, sponsored by Warner Robins Air Logistics Center (ALC), Robins Air Force Base, Georgia, has developed a robot-compatible apparatus that efficiently accelerates pellets of dry ice with a high-speed rotating wheel. In comparison to the more conventional compressed air 'sandblast' pellet accelerators, the turbine system can achieve higher pellet speeds, has precise speed control, and is more than ten times as efficient. A preliminary study of the apparatus as a depaint technology has been undertaken. Depaint rates of military epoxy/urethane paint systems on 2024 and 7075 aluminum panels as a function of pellet speed and throughput have been measured. In addition, methods of enhancing the strip rate by combining infra-red heat lamps with pellet blasting and by combining the use of environmentally benign solvents with the pellet blasting have also been studied. The design and operation of the apparatus will be discussed along with data obtained from the depaint studies.

Foster, C. A.↗

Drug marker absorption in relation to pellet size, gastric motility and viscous meals in humans

PURPOSE: The objective of this study was to evaluate drug marker absorption in relation to the gastric emptying (GE) of 0.7 mm and 3.6 mm enteric coated pellets as a function of viscosity and the underlying gastric motility. METHODS: Twelve subjects were evaluated in a 3-way crossover study. 0.7 mm caffeine and 3.6 mm acetaminophen enteric coated pellets were concurrently administered with a viscous caloric meal at the levels of 4000, 6000 and 8000 cP. Gastric motility was simultaneously measured with antral manometry and compared to time events in the plasma profiles of the drug markers. RESULTS: Caffeine, from the 0.7 mm pellets, was observed significantly earlier in the plasma than acetaminophen, from the 3.6 mm pellets, at all levels of viscosity. Motility related size differentiated GE was consistently observed at all viscosity levels, however, less variability was observed with the 4000 cP meal. Specifically, the onset of absorption from the of 3.6 mm pellets correlated with the onset of Phase II fasted state contractions (r = 0.929, p < 0.01). CONCLUSIONS: The timeframe of drug marker absorption and the onset of motility events were not altered within the range of viscosities evaluated. Rather, the differences in drug marker profiles from the non-digestible solids were most likely the result of the interaction between viscosity and motility influencing antral flow dynamics. The administration of the two sizes of pellets and a viscous caloric meal with subsequent monitoring of drug marker profiles is useful as a reference to assess the influence of motility patterns on the absorption profile of orally administered agents.

NASA Center JSC↗

Manufacture of Regularly Shaped Sol-Gel Pellets

An extrusion batch process for manufacturing regularly shaped sol-gel pellets has been devised as an improved alternative to a spray process that yields irregularly shaped pellets. The aspect ratio of regularly shaped pellets can be controlled more easily, while regularly shaped pellets pack more efficiently. In the extrusion process, a wet gel is pushed out of a mold and chopped repetitively into short, cylindrical pieces as it emerges from the mold. The pieces are collected and can be either (1) dried at ambient pressure to xerogel, (2) solvent exchanged and dried under ambient pressure to ambigels, or (3) supercritically dried to aerogel. Advantageously, the extruded pellets can be dropped directly in a cross-linking bath, where they develop a conformal polymer coating around the skeletal framework of the wet gel via reaction with the cross linker. These pellets can be dried to mechanically robust X-Aerogel.

Leventis, Nicholas↗

Shock and vibration tests of uranium mononitride fuel pellets for a space power nuclear reactor

Shock and vibration tests were conducted on cylindrically shaped, depleted, uranium mononitride (UN) fuel pellets. The structural capabilities of the pellets were determined under exposure to shock and vibration loading which a nuclear reactor may encounter during launching into space. Various combinations of diametral and axial clearances between the pellets and their enclosing structures were tested. The results of these tests indicate that for present fabrication of UN pellets, a diametral clearance of 0.254 millimeter and an axial clearance of 0.025 millimeter are tolerable when subjected to launch-induced loads.

Adams, D. W.↗

Pneumatic Pellet-Transporting System

Pneumatic system transports food pellets to confined animals. Flow of air into venturi assembly entrains round pellets, drawing them from reservoir into venturi for transport by airflow. Pneumatic pellet-transporting system includes venturi assembly, which creates flow of air that draws pellets into system.

Wood, George↗

Internal impacted screw-locking pellet

An elongate fastener having an engaging surface engageable with an engaging surface of a fastener's mate includes a hole extending through a portion of the fastener and having a top opening and a bottom floor, a locking pellet disposed near the bottom floor, a discharge channel communicating between the pellet and through the engaging surface of the fastener and opening out toward the engaging surface of the fastener's mate, and an impact pin in the hole having a top portion protruding through the top opening and a bottom portion near the locking pellet, whereby the pin drives the locking pellet through the discharge channel against the engaging surfaces of the fastener and the fastener's mate whereby to lock the fastener against the fastener's mate.

MacMartin, Malcolm J.↗

Steam reforming of n-hexane on pellet and monolithic catalyst beds. A comparative study on improvements due to heat transfer

Monolithic catalysts with higher available active surface areas and better thermal conductivity than conventional pellets beds, making possible the steam reforming of fuels heavier than naphtha, were examined. Performance comparisons were made between conventional pellet beds and honeycomb monolith catalysts using n-hexane as the fuel. Metal-supported monoliths were examined. These offer higher structural stability and higher thermal conductivity than ceramic supports. Data from two metal monoliths of different nickel catalyst loadings were compared to pellets under the same operating conditions. Improved heat transfer and better conversion efficiencies were obtained with the monolith having higher catalyst loading. Surface-gas interaction was observed throughout the length of the monoliths.

Source record↗

Fusible pellet transport and storage of heat

A new concept for both transport and storage of heat at high temperatures and heat fluxes is introduced and the first steps in analysis of its feasibility is taken. The concept utilizes the high energy storage capability of materials undergoing change of phase. The phase change material, for example a salt, is encapsulated in corrosion resistant sealed pellets and transported in a carrier fluid to heat source and storage. Calculations for heat transport from a typical solar collector indicate that the pellet mass flow rates are relatively small and that the required pumping power is only a small fraction of the energy transport capability of the system. Salts and eutectic salt mixtures as candidate phase change materials are examined and discussed. Finally, the time periods for melting or solidification of sodium chloride pellets is investigated and reported.

Bahrami, P. A.↗

A gel-halo sample pellet: The best of both worlds? Stubby zones without a constricted sample gate

This reduces cell quantity, in the same way as does a narrower bore sample gate. The cells are confined to the center of the gate, inside a halo of electrolyte (D-1 buffer, here) immobilized by gel, which halo mechanically retains the ice pellet in position prior to thaw. The gel halo can be retained by the same gentle ridge as is contemplated for the ice pellet, and the ice pellet can be likewise retained within the gel halo.

Hinckley, J. O. N.↗

Cleaning By Blasting With Pellets Of Dry Ice

Dry process strips protective surface coats from parts to be cleaned, without manual scrubbing. Does not involve use of flammable or toxic solvents. Used to remove coats from variety of materials, including plastics, ceramics, ferrous and nonferrous metals, and composites. Adds no chemical-pollution problem to problem of disposal of residue of coating material. Process consists of blasting solid carbon dioxide (dry ice) pellets at surface to be cleaned. Pellets sublime on impact and pass into atmosphere as carbon dioxide gas. Size, harness, velocity, and quantity of pellets adjusted to suit coating material and substrate.

Fody, Jody↗

Casting Silicon Pellets From Powder

New technique converts finely powdered silicon into solid pellets. Fine silicon powder melts in thin quartz bubble that breaks upon cooling, leaving behind crack-free pellet of silicon.

Farrier, E. G.↗

Pellet bed reactor for nuclear propelled vehicles: Part 1: Reactor technology

The pellet bed reactor (PBR) for nuclear propelled vehicles is briefly discussed. Much of the information is given in viewgraph form. Viewgraphs include information on the layout for a Mars mission using a PBR nuclear thermal rocket, the rocket reactor layout, the fuel pellet design, materials compatibility, fuel microspheres, microsphere coating, melting points in quasibinary systems, stress analysis of microspheres, safety features, and advantages of the PBR concept.

El-Genk, Mohamed S.↗

Pellet bed reactor for nuclear propelled vehicles: Part 2: Missions and vehicle integration trades

Mission and vehicle integration tradeoffs involving the use of the pellet bed reactor (PBR) for nuclear powered vehicles is discussed, with much of the information being given in viewgraph form. Information is given on propellant tank geometries, shield weight requirements for conventional tank configurations, effective specific impulse, radiation mapping, radiation dose rate after shutdown, space transfer vehicle design data, a Mars mission summary, sample pellet bed nuclear orbit transfer vehicle mass breakdown, and payload fraction vs. velocity increment.

Haloulakos, V. E.↗

Charge Transfer Process During Collision of Riming Graupel Pellet with Small Ice Crystals within a Thundercloud

A charge transfer process during the collision of a riming graupel pellet and an ice-crystal at low temperature is proposed. During riming, the surface structure of graupel deviates from perfect crystalline structure. A concept of quasi-solid layer (QSL) formation on the surface is introduced. This QSL contains defects formed during riming. In absence of impurities, positively charged X-defect abundance is considered in the outer layer. These defects are assumed to be the charge carriers during the charge transfer process. Some part of the QSL is stripped off by the colliding ice crystals, which thereby gain some positive charge, leaving the graupel pellet negatively charged. With the proposed model, fC to pC of charge transfer is observed per collision. A transition temperature between -10 C to -15 C is also noted beyond which the QSL concept does not hold. This transition temperature is dependent on the bulk liquid water content of the cloud.

Datta, Saswati↗