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At least 19 records

Thioaptamer Diagnostic System (TDS)

AM Biotechnologies, LLC, in partnership with Sandia National Laboratories, has developed a diagnostic device that quickly detects sampled biomarkers. The TDS quickly quantifies clinically relevant biomarkers using only microliters of a single sample. The system combines ambient-stable, long shelf-life affinity assays with handheld, microfluidic gel electrophoresis affinity assay quantification technology. The TDS is easy to use, operates in microgravity, and permits simultaneous quantification of 32 biomarkers. In Phase I of the project, the partners demonstrated that a thioaptamer assay used in the microfluidic instrument could quantify a specific biomarker in serum in the low nanomolar range. The team also identified novel affinity agents to bone-specific alkaline phosphatase (BAP) and demonstrated their ability to detect BAP with the microfluidic instrument. In Phase II, AM Biotech expanded the number of ambient affinity agents and demonstrated a TDS prototype. In the long term, the clinical version of the TDS will provide a robust, flight-tested diagnostic capability for space exploration missions.

Yang, Xianbin↗

M2020/MSL: TDS (Terminal Descent Sensor) DEA (Digital Electronics Assembly)

TDS is the radar used in MSL mission to land Curiosity rover on Mars. TDS will be used again in M2020 mission. DEA is the brain of the TDS where it serves as the controller and digital signal processor. The DEA commands TDS to cycle through the antenna beams making measurements using one of the 6 antenna beams at a time. DEA uses beam sequences and parameter tables to generate measurements. The most important measurements are velocity and range that are used to guide the landing of Curiosity rover. DEA performs these measurement tasks using radar signal processing FPGA firmware and radar microprocessor ‘s hardware and software.

Ashtijou, Mohammad↗

TDS and BMT for CASES ADF (ADF RAMS), acceptance test

The Controls, Astrophysics, and Structures Experiment (CASES) is a proposed experiment to collect x ray images of the galactic center and solar disk with unprecedented resolution. This requires precision pointing and suppression of vibrations in the long, flexible structure that comprises the 32-m x ray telescope optical bench. Two separate electro-optical sensors systems are provided for the ground test facility (GTF). The Boom Motion Tracker (BMT) measures eigenvector data for post-mission use in system identification. The Tip Displacement Sensor (TDS) measures boom tip position and is used as feedback for the closed-loop control system that stabilizes the boom. The deployment and testing of the BMT and TDS systems is summarized.

Davis, Hugh W.↗

Interfacial chemistry of a perfluoropolyether lubricant studied by XPS and TDS

The interfacial chemistry of Fomblin Z25, a commercial perfluoropolyether used as lubricant for space applications, with different metallic surfaces: 440C steel, gold and aluminum was studied. Thin layers of Fomblin Z25 were evaporated onto the oxide-free substrates and the interfacial chemistry studied using XPS and TDS. The reactions were induced by heating the substrate and by rubbing the substrate with a steel ball. Gold was found to be completely unreactive towards Fomblin at any temperature. Reaction at room temperature was observed only in the case of the aluminum substrate, the most reactive towards Fomblin Z25 of the substrates studied. It was necessary to heat the 440C steel substrate to 190 degree C to induce decomposition of the fluid. The degradation of the fluid was indicated by the formation of a debris layer at the interface. This debris layer, composed of inorganic and organic reaction products, when completely formed, passivated the surface from further attack to the Fromblin on top. The tribologically induced reactions on 440C steel formed a debris layer of similar chemical characteristics to the thermally induced layer. In all cases, the degradation reaction resulted in preferential consumption of the difluoroformyl carbon (-OCF2O-).

Herrera-Fierro, Pilar C.↗

Pioneer 7 TDS requirements

Near-earth and deep space tracking and data acquisition requirements for Pioneer 7 space probe

Source record↗

System integration of a Telerobotic Demonstration System (TDS) testbed

The concept for and status of a telerobotic demonstration system testbed that integrates teleoperation and robotics is described. The components of the telerobotic system are described and the ongoing projects are discussed. The system can be divided into two sections: the autonomous subsystems, and the additional interface and support subsystems including teleoperations. The workings of each subsystem by itself and how the subsystems integrate into a complete system is discussed.

Myers, John K.↗

HELIOS Third Joint Working Group Meeting

During the past six months since the Second Helios Joint Working Group Meeting held 27-30 April 1970 at Goddard Space Flight Center, the TDS Sub-Group supported the Helios Project Office and the other Sub-Groups in the timely disposition of action items and the dissemination of information pertinent to the development of interface documentation. Of particular importance during this time period was the Project's decision to incorporate a single-channel telemetry system design aboard the spacecraft. The TDS Sub-Group participated actively in the process that led to this decision. Still under active study with TDS participation is the pending Project Office decision regarding the incorporation of a ranging capability within the telecommunications design. The TDS Sub-Group assisted the Mission Analysis and Operations Sub-Group in establishment of a study effort concerning the Near-Earth Sequence of Events from launch to launch plus 8 hours. This study, which will provide valuable data for the spacecraft telecommunications design, will include participation by the Experiment, Launch Vehicle, Spacecraft, as well as the TDS and MA&O Sub-Groups. Also during the past 6-month period, the TDS, in conjunction with the Spacecraft Sub-Group, initiated activity to develop the Helios Spacecraft/TDS Compatibility Test Plans and Procedures. Activity concerning the foregoing interface discussions has been and will continue to be based upon the "TDS Estimated Capabilities Document for the Helios Missions" (613-1), and the "DSN/Flight Project Interface Design Handbook" (810-5). These will continue to be considered TDS controlling documents until specific Helios Project/TDS interface documentation is generated and signed off by the respective parties. In addition to the above, the DSN continued the Helios Trainee Program with seven GfW/DFVLR trainees in residence at JPL. Two trainees will complete their year's residency concurrent with the Third Helios Joint Working Group Meeting, while four new trainees are expected to arrive following the Third Helios Joint Working Group Meeting. These and other activities are reported in detail in the paragraphs that follow.

Ousley, Gilbert↗

Implementing the Mars Science Laboratory Terminal Descent Sensor Field Test Campaign

The Mars Science Laboratory (MSL) will deliver a 900 kg rover to the surface of Mars in August 2012. MSL will utilize a new pulse-Doppler landing radar, the Terminal Descent Sensor (TDS). The TDS employs six narrow-beam antennas to provide unprecedented slant range and velocity performance at Mars to enable soft touchdown of the MSL rover using a unique sky crane Entry, De-scent, and Landing (EDL) technique. Prior to use on MSL, the TDS was put through a rigorous verification and validation (V&V) process. A key element of this V&V was operating the TDS over a series of field tests, using flight-like profiles expected during the descent and landing of MSL over Mars-like terrain on Earth. Limits of TDS performance were characterized with additional testing meant to stress operational modes outside of the expected EDL flight profiles. The flight envelope over which the TDS must operate on Mars encompasses such a large range of altitudes and velocities that a variety of venues were neces-sary to cover the test space. These venues included an F/A-18 high performance aircraft, a Eurocopter AS350 AStar helicopter and 100-meter tall Echo Towers at the China Lake Naval Air Warfare Center. Testing was carried out over a five year period from July 2006 to June 2011. TDS performance was shown, in gen-eral, to be excellent over all venues. This paper describes the planning, design, and implementation of the field test campaign plus results and lessons learned.

Mars Science Laboratory (MSL)↗

Implementing the Mars Science Laboratory Terminal Descent Sensor Field Test Campaign

Overall, the MSL TDS Field Test campaign was very successful. TDS was shown to perform extremely well over the required operational envelope. Early BB TDS field tests uncovered a number of issues, but none that invalidated the TDS design or implementation. EM TDS tests uncovered minor things of interest, but nothing of concern. Value of testing hardware in the field was demonstrated and significantly contributed to the overall TDS V&V effort. Over the 5-plus year field test campaign, numerous lessons were learned that will inform future field test efforts.

Terminal Descent Sensor↗

Miniature EPSPs and sensory encoding in the primary afferents of the vestibular lagena of the toadfish, Opsanus tau

The synaptic activity transmitted from vestibular hair cells of the lagena to primary afferent neurons was recorded in vitro using sharp, intracellular microelectrodes. At rest, the activity was composed of miniature excitatory postsynaptic potentials (mEPSPs) at frequencies from 5 to 20/s and action potentials (APs) at frequencies betwen 0 and 10/s. mEPSPs recorded from a single fiber displayed a large variability. For mEPSPs not triggering APs, amplitudes exhibited an average coefficient of variance (CV) of 0.323 and rise times an average CV of 0.516. APs were only triggered by mEPSPs with larger amplitudes (estimated 4-6 mV) and/or steeper maximum rate of rise (10.9 mV/ms, +/- 3.7 SD, n=4 experiments) compared to (3.50 mV/ms, +/-0.07 SD, n=6 experiments) for nontriggering mEPSPs. The smallest mEPSPs showed a fast rise time (0.99 ms between 10% and 90% of peak amplitude) and limited variability across fibers (CV:0.18) confirming that they were not attenuated signals, but rather represented single-transmitter discharges (TDs). The mEPSP amplitude and rise-time relationship suggests that many mEPSPs represented several, rather than a single pulse of secretion of TDs. According to the estimated overall TD frequency, the coincidence of TDs contributing to the same mEPSP were not statistically independent, indicating a positive interaction between TDs that is reminiscent of the way subminiature signals group to form miniature signals at the neuromuscular junction. Depending on the duration and intensity of efferent stimulation, a complete block of AP initiation occurred either immediately or after a delay of a few seconds. Efferent stimulation did not significantly change AP threshold level, but abruptly decreased mEPSP frequency to a near-complete block that followed the block of APs. Maximum mEPSP rate of rise decreased during, and recovered progressively after, efferent stimulation. After termination of efferent stimulation, mEPSP amplitude did not recover instantly and for a few seconds the amplitude distribution of synaptic events showed fewer large-amplitude events than during the control period. This confirms that mEPSP amplitude and rate of rise properties, which are critical for triggering afferent APs, are modified by efferent activity. The depression of afferent AP firing during efferent stimulation corresponded to a decrease in mEPSP frequency and, to a lesser extent, a decrease in mEPSP amplitude and rate of rise, suggesting, a decrease in the level of interaction among TDs contibuting to a mEPSP.

Non-NASA Center↗

Assistant for Analyzing Tropical-Rain-Mapping Radar Data

A document is defined that describes an approach for a Tropical Rain Mapping Radar Data System (TDS). TDS is composed of software and hardware elements incorporating a two-frequency spaceborne radar system for measuring tropical precipitation. The TDS would be used primarily in generating data products for scientific investigations. The most novel part of the TDS would be expert-system software to aid in the selection of algorithms for converting raw radar-return data into such primary observables as rain rate, path-integrated rain rate, and surface backscatter. The expert-system approach would address the issue that selection of algorithms for processing the data requires a significant amount of preprocessing, non-intuitive reasoning, and heuristic application, making it infeasible, in many cases, to select the proper algorithm in real time. In the TDS, tentative selections would be made to enable conversions in real time. The expert system would remove straightforwardly convertible data from further consideration, and would examine ambiguous data, performing analysis in depth to determine which algorithms to select. Conversions performed by these algorithms, presumed to be correct, would be compared with the corresponding real-time conversions. Incorrect real-time conversions would be updated using the correct conversions.

James, Mark↗

Tangential discontinuities in the solar wind - Correlated field and velocity changes and the Kelvin-Helmholtz instability

Three-dimensional Helios plasma and field data are used to investigate the relative changes in direction of the velocity and magnetic field vectors across tangential discontinuities (TDs) in the solar wind at solar distances of 0.29-0.50 AU. It is found for TDs with large Delta-v and (Delta-B)/B that Delta-v and Delta-B are closely aligned with each other, in agreement with the unexpected results of previous studies of TDs observed at 1 AU and beyond. It is shown that this effect probably results from the destruction by the Kelvin-Helmholtz instability of TDs for which Delta-v and Delta-B are not aligned. The observed decrease in the number of interplanetary discontinuities with increasing solar distance may be associated with the growth of the Kelvin-Helmholtz instability with decreasing Alfven speed.

Neugebauer, M.↗

Studies in knowledge-based diagnosis of failures in robotic assembly

The telerobot diagnostic system (TDS) is a knowledge-based system that is being developed for identification and diagnosis of failures in the space robotic domain. The system is able to isolate the symptoms of the failure, generate failure hypotheses based on these symptoms, and test their validity at various levels by interpreting or simulating the effects of the hypotheses on results of plan execution. The implementation of the TDS is outlined. The classification of failures and the types of system models used by the TDS are discussed. A detailed example of the TDS approach to failure diagnosis is provided.

Lam, Raymond K.↗