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At least 19 records

Programs Enabling Deep Technology Transfer from National Labs

To maximize the technology transfer potential, it is important to create an ecosystem for the inventors to adapt the technologies developed for basic science to successful commercial ventures. In this white paper we present a brief overview of technology transfer programs at high energy physics (HEP) laboratories with a focus on the programs at Fermilab and KEK, and identify opportunities and recommendations for increasing partnerships and commercialization at HEP-centric laboratories.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Technology Transfer from Los Alamos [Slides]

The Feynman Center for innovation is responsible for all of the Laboratory’s technology transfer activities. The goal of technology transfer is to leverage federal R&D investments to promote U.S. economic competitiveness and job growth, while supporting the Laboratory’s national security mission objectives. FCI authorities and functions originate from federal and state statutes and prime contract directives.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Panel Session 108: Technology Transfer and Commercialization: Innovative Solutions for Global Opportunities

This panel focus was to build the connection between innovative solutions and the various industries looking for more efficient methods, products, and processes in Tech Transfer and Commercialization. This panel had interest across the entire conference base, whether they are encountering a challenge, introducing an innovative solution, or are the host that is trying to get from a pure research / Research, Development, Demonstration, Testing, and Evaluation solution to one that is commercially viable and robust enough for long term and/or high risk deployment scenarios and which will support greater chance of success and positive outcomes. Panelists with presentations: Practical, Successful Technology Transfer (Laurie Judd); Technology Needs for Clean-up of Mercury Contamination on the Oak Ridge Reservation (Renee Echols); US DOE Office of Technology Transitions (Kyle Wiley); Technology Transfer in Support of Delivering Clean-up Missions (Kristan Schruder); Mission to Market (J. Chris Ford)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

MRCI Task 5: Promoting Regional Technology Transfer Final Summary Report

The goal of the MRCI Task 5 – Promoting Regional Technology Transfer is to leverage existing and new relationships with critical CCUS stakeholders (national and international stakeholders include state geological surveys, universities, industrial partners and advisors, energy production and utilization companies, and NGOs) within the regional initiative and globally and become a key resource for CCUS information, acceptance, and development. Work completed under Task 5 is categorized through four actions: • Promote acceleration of CCUS deployment by providing general support for commercialization and technology transfer • Compile and communicate information from previous tasks to interested stakeholders • Engage with federal and state governments, industry consortia and NGOs • Engage with global institutions

CCUS,Midwest,Midwest Regional Carbon Initiative,Mi↗

Technology Transfer Overview [Slides]

Slides for a presentation providing an overview of the "Technology Transfer" topic as a part of the Oppenheimer Science and Energy Leadership Program.

42 ENGINEERING↗

Lawrence Livermore National Laboratory – Innovation and Partnerships Office (IPO): FY24 Technology Transfer Report (2025 Report V3)

Lawrence Livermore National Laboratory’s (LLNL) Innovation and Partnerships Office (IPO) is the focal point for Laboratory engagement with industry. Organizations partner with LLNL to unlock the commercial viability of breakthrough technologies invented at the Laboratory and collaborate to mature them in order to solve complex industry challenges. LLNL technology transfer connects cutting-edge science with real-world applications, empowering businesses to thrive while advancing the nation’s technological edge. We do this by identifying new economic opportunities, protecting LLNL intellectual property (IP) and transferring it to the private sector through licensing and partnerships

42 ENGINEERING↗

Revival and Technology Transfer of 90SrTiO3 Production for Heat Source Applications

Demand for radioisotope power systems (RPS) appears to be on the rise, and it is unlikely that this new demand can be met by plutonium-238. As a result, new heat source designs are under development. One such design is Z1. Z1 is a strontium-90 demonstration heat source developed by Zeno Power Systems in collaboration with the University of Dayton Research Institute and the Pacific Northwest National Laboratory. SrTiO3 was chosen as the fuel form for Z1. SrTiO3 was used to produce dozens of terrestrial RPS decades ago. While this indicates the technology is proven, the skill and experience necessary to effectively produce SrTiO3 has been lost. Recapturing SrTiO3 production technology therefore became necessary. Development started with non-radioactive surrogate experiments using natural strontium. This work showed that the old Oak Ridge flowsheets for SrTiO3 production are quite robust, but some critical pieces of the technology are left out of the old documentation. Specifically, particle sizes of the reagents are critical to producing a phase pure SrTiO3. If the reagent particles are not the right size, then a significant Sr3Ti2O7 phase impurity is observed. This phase impurity was proven to be the result of an incomplete reaction between the strontium and titanium precursors. This technology was transferred to Pacific Northwest National Laboratory where the technology was adapted for use in a hot cell. With the adaptations complete, this technology was used to produce the fuel for Z1 late last year. This represents the first new heat source design produced in the U.S. in over 40 years.

90Sr, strontium titanate, SrTi03, RTG, Radioisotop↗

Technology Transfer Excellence Award NTXBio

While a scientist at Los Alamos National Laboratory, Dr. Alex Koglin developed two compounds to create a better vaccine for Tuberculosis (TB). In 2015, Dr. Koglin took an entrepreneurial leave of absence from the Laboratory to start NTXBio, LLC. His objective was to develop and commercialize a TB vaccine based on two compounds he created while a scientist at the Los Alamos. In 2018, a total of 1.5 million people died from TB. According to the World Health Organization TB is the leading infectious disease resulting in death worldwide. Approximately one-quarter of the world’s population is infected with mycobacterium tuberculosis, the bacteria that causes TB. Dr. Koglin non-exclusively licensed the two compounds from Los Alamos and began further development of the technology in collaboration with the Government of South Africa and universities to address the need for a vaccine to prevent TB. In their research and development of the compounds there was no evidence of cross resistance between other bacteria and the bacteria that causes TB. The compounds were tested in mouse models and demonstrated they can treat TB. Also, the tests have not shown any of the massive side effects that the current treatments for TB are showing. The company started production of the compounds using current manufacturing processes. Using these processes NTXBio could not produce the compounds at a reasonable price to be available for patients in third world countries. The company shifted to developing a new methodology “invitro synthetic biology” that can increase the production of these compounds and other vaccine molecules in a more affordable way. Dr. Koglin’s startup NTXBio is working to positively influence and secure the world vaccine supply by developing rapid on-demand production of the full spectrum of protein vaccines. Starting with the TB vaccine and advancing to common childhood vaccines, emergency and experimental vaccines such as those needed for COVID-19. NTXBio is capable of accelerated prototyping and manufacturing with increased purity and greater stability while reducing both cost and production time. The newly developed production methodology can be applied to not only the TB compounds licensed from Los Alamos, but also to their compounds that advance vaccine production for other diseases. Their technology produces vaccines fast enough to be fully deployable in areas without the need of specialized storage conditions and response times.

60 APPLIED LIFE SCIENCES↗

The Geothermal Entrepreneurship Organization (GEO) Accelerating Technology Transfer, Testing and Adoption of Cutting-edge Extreme Environment Drilling

The Geothermal Entrepreneurship Organization launched in 2019 with the goal of building a geothermal innovation ecosystem at the University of Texas at Austin (UT Austin), and in the State of Texas at large. The theses underlying the work of GEO were 1) that with targeted advocacy, recruitment, organization, and coalition building, research institutions with legacy excellence in petroleum and geosystems engineering could become engines of geothermal innovation, research and development; 2) that startups were the appropriate vehicle to speed these innovations from the lab into the field, and building a geothermal startup ecosystem in Texas would not only advance next generation geothermal concepts into the field, but also help spur oil and gas engagement in the space, and 3) that with targeted engagement, education, and recruitment across stakeholders in the oil and gas industry and the State of Texas generally, the oil and gas industry, and other legacy oil and gas entities in the State could become sources of large scale deployment of geothermal energy. The overall goal was to create a ‘snowball’ effect, where targeted impactful actions would catalyze self-sustaining, organic growth of a new geothermal ecosystem in the State of Texas. That goal was achieved through GEO’s work. To test its theses, GEO began work by interviewing and recruiting UT Austin faculty and alumni into geothermal. At the beginning of the GEO project, there was no geothermal activity ongoing within the UT Austin Petroleum and Geosystems Engineering Department, the Bureau of Economic Geology, or the Jackson School of Geoscience, and many faculty approached had not before considered how their skillsets might apply in the space. By the end of the project period, three major research consortia focused on geothermal were launched as a result of GEO’s work, one at the Bureau of Economic Geology, one within the Petroleum and Geosystems Engineering Department, and another organized by GEO across six research institutions across the State of Texas, called the Texas Geothermal Institute. Geothermal curricula was launched at UT Austin, and UT Austin began attracting new geothermal enthusiasts into its faculty, including Dr. Silviu Livescu, former Chief Scientist of Baker Hughes. Startups recruited and mentored by GEO launched, raised funding, and deployed (or are currently deploying) their concepts in the field. By the end of the project period, the GEO concept expanded to faculty beyond UT Austin to other institutions, like Texas A&M, the University of Houston, and Rice University, and geothermal engagement began at those institutions as well. Multiple faculty members and alumni across these institutions launched geothermal startup companies, launched geothermal research consortia, and/or began teaching geothermal courses. In 2020, GEO launched what was to become the largest geothermal conference in the world by its second year, ‘PIVOT – From Hydrocarbons to Heat’, and the resulting momentum catalyzed the Society of Petroleum Engineers to launch a geothermal technical section, drove more startups to launch out of the ecosystem, and drove actors in the State of Texas, NGOs, and stakeholders globally to become engaged. Riding this momentum, the Texas Geothermal Energy Alliance was launched, the first ever industry association dedicated to advancing geothermal energy in the State of Texas. The Texas geothermal ecosystem after only two years of building and support is now robust, quickly growing, and self-sustaining. By 2021, the Texas geothermal ecosystem had attracted the attention of philanthropists, funding entities, media, and influencers outside of Texas, and GEO’s executive director was invited to give a TED talk about oil and gas engagement in building the future of geothermal energy, which elevated the success of the ecosystem to a global audience.

15 GEOTHERMAL ENERGY↗

Measurement of Iodine, Iodide, and Iodate in Hanford Tank Waste: Technology Transfer from PNNL to Hanford 222-S Laboratory

This report summarizes the measurement of the inorganic chemical forms of iodine in Hanford tank waste. The Hanford tank wastes have roughly a part per million iodine. Part of the iodine is the long-lived beta emitter 129I, and the rest is stable 127I. Because tank waste iodine is radioactive and radiotoxic, its chemical form must be known so that its behavior in the vitrification process can be reliably known and anticipated in various waste streams (glass, secondary liquid and solid waste, and offgas emissions) at Hanford. Iodine in tank wastes exists in the inorganic chemical forms iodide and iodate (and possibly also periodate) and also as organic forms such as alkyl iodides. The measurement of organic iodides is very different from the measurement of inorganic forms and is outside the scope of this report. The inorganic chemical forms are chemically separated, in sequence, from the raw tank waste using solvent extractions and several redox reactions, then measured by ICP-MS. The inorganic chemical forms of iodine are chemically reactive, and so is the tank waste. The chemistry must be carefully designed to avoid unintended reactions that could convert one form of iodine to another during the analysis, which would skew the data and report iodine in the wrong chemical form. This iodine analysis, developed at PNNL, is being transferred to the DOE 222-S Laboratory on the Hanford Site, in Washington State, for implementation during waste processing operations.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Measurement of Total, Elemental, and Methyl Mercury in Hanford Tank Waste: Technology Transfer from PNNL to Hanford 222-S Laboratory

This report describes the chemical separations used to measure the amount and chemical form of mercury in Hanford tank waste and provides the technical basis and recommendations for transferring and implementing this new ultra-trace mercury analytical technique at Hanford’s 222-S Laboratory. In the Hanford tank waste, mercury can exist as either elemental, inorganic, or organic mercury species. Of key interest is understanding the quantification and speciation of total (elemental + inorganic + organic), elemental, and organic (assumed to be only methyl mercury) mercury. The tanks may also have other organic mercury species, but their direct measurement is outside the scope of this report.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Technology Transfer from Fermi Research Alliance to Itasca Plastics for the purpose of Commercializing Scintillator Material

Researchers at the Fermi National Accelerator Laboratory (Fermilab) developed extruded plastic scintillator in the late 1990s, which was first used in the D-Zero experiment. Extruded plastic scintillator is currently produced at Fermilab and is used in particle detectors worldwide. The purpose of this CRADA is to transfer the knowledge related to the Fermilab extrusion process to Itasca Plastics, Inc. (Itasca Plastics). Much of this knowledge is contained in documentation that is in the public domain, although it is distributed over several communications (papers, conference records, etc.) and over several years. Under this CRADA Fermilab will assemble the information, provide it to Itasca Plastics and provide limited consulting to complete the knowledge transfer. If the transfer is successful, Itasca Plastics will be able to establish a U.S. commercial manufacturing capability for extruded scintillator material that can be used for high energy physics and commercial applications.

36 MATERIALS SCIENCE↗