Temperature-compensation circuit stabilizes performance of vidicons
A simple transistor circuit uses a thermistor to change the vidicon target potential in relation to temperature differences.
Source record↗
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Prolonging genetic circuit stability through adaptive evolution of overlapping genes
Abstract The development of synthetic biological circuits that maintain functionality over application-relevant time scales remains a significant challenge. Here, we employed synthetic overlapping sequences in which one gene is encoded or ‘entangled’ entirely within an alternative reading frame of another gene. In this design, the toxin-encoding relE was entangled within ilvA, which encodes threonine deaminase, an enzyme essential for isoleucine biosynthesis. A functional entanglement construct was obtained upon modification of the ribosome-binding site of the internal relE gene. Using this optimized design, we found that the selection pressure to maintain functional IlvA stabilized the production of burdensome RelE for >130 generations, which compares favorably with the most stable kill-switch circuits developed to date. This stabilizing effect was achieved through a complete alteration of the allowable landscape of mutations such that mutations inactivating the entangled genes were disfavored. Instead, the majority of lineages accumulated mutations within the regulatory region of ilvA. By reducing baseline relE expression, these more ‘benign’ mutations lowered circuit burden, which suppressed the accumulation of relE-inactivating mutations, thereby prolonging kill-switch function. Overall, this work demonstrates the utility of sequence entanglement paired with an adaptive laboratory evolution campaign to increase the evolutionary stability of burdensome synthetic circuits.
59 BASIC BIOLOGICAL SCIENCES↗
Electronic circuit delivers pulse of high interval stability
Circuit generates a pulse of high interval stability with a complexity level considerably below systems of comparable stability. This circuit is being used as a linear frequency discriminator in the signal conditioner of the Apollo command module.
Fisher, B.↗
Remote preamplifier circuit maintains stability over wide temperature range
Circuit remains stable over a wide temperature range while preamplifying light signals falling on a photocell and transmitting them through a transmission line to a remote amplifier. The circuits preamplifier consists of a grounded emitter NPN stage followed by a PNP emitter.
Mac~naughton, R. G.↗
Method and apparatus for transfer function simulator for testing complex systems
A method and apparatus for testing the operation of a complex stabilization circuit in a closed loop system is presented. The method is comprised of a programmed analog or digital computing system for implementing the transfer function of a load thereby providing a predictable load. The digital computing system employs a table stored in a microprocessor in which precomputed values of the load transfer function are stored for values of input signal from the stabilization circuit over the range of interest. This technique may be used not only for isolating faults in the stabilization circuit, but also for analyzing a fault in a faulty load by so varying parameters of the computing system as to simulate operation of the actual load with the fault.
Kavaya, M. J.↗
Network analysis of memristive device circuits: dynamics, stability and correlations
Abstract Networks with memristive devices are a potential basis for the next generation of computing devices. They are also an important model system for basic science, from modeling nanoscale conductivity to providing insight into the information-processing of neurons. The resistance in a memristive device depends on the history of the applied bias and thus displays a type of memory. The interplay of this memory with the dynamic properties of the network can give rise to new behavior, offering many fascinating theoretical challenges. But methods to analyze general memristive circuits are not well described in the literature. In this paper we develop a general circuit analysis for networks that combine memristive devices alongside resistors, capacitors and inductors and under various types of control. We derive equations of motion for the memory parameters of these circuits and describe the conditions for which a network should display properties characteristic of a resonator system. For the case of a purely memresistive network, we derive Lyapunov functions, which can be used to study the stability of the network dynamics. Surprisingly, analysis of the Lyapunov functions show that these circuits do not always have a stable equilibrium in the case of nonlinear resistance and window functions. The Lyapunov function allows us to study circuit invariances, wherein different circuits give rise to similar equations of motion, which manifest through a gauge freedom and node permutations. Finally, we identify the relation between the graph Laplacian and the operators governing the dynamics of memristor networks operators, and we use these tools to study the correlations between distant memristive devices through the effective resistance.
97 MATHEMATICS AND COMPUTING↗
Design and development of microelectronic circuits for stabilization of a gas bearing gyro servo loop Phase completion report
Microelectronic servoamplifier design, tests, and evaluation for stabilizing gas bearing gyro servo loops
Friedman, B.↗
Searching Circuit For A Servoloop
Feedback error voltage forced into range of stability. Circuit connected in series with error-voltage line of feedback loop. When loop operates normally in stable region, searching circuit does not disturb operation, and error-voltage output of loop filter is control voltage. When servo unlocks and error-voltage output of loop filter wanders into unstable range, searching circuit forces control voltage to sweep through stable region repeatedly until lock recovered. Consists of two halves identical except polarities of some parts in each half opposite of corresponding parts in other half.
Sigman, E. H.↗
Comparison of Kill Switch Toxins in Plant-Beneficial Pseudomonas fluorescens Reveals Drivers of Lethality, Stability, and Escape
Kill switches provide a biocontainment strategy in which unwanted growth of an engineered microorganism is prevented by expression of a toxin gene. A major challenge in kill switch engineering is balancing evolutionary stability with robust cell killing activity in application relevant host strains. Understanding host-specific containment dynamics and modes of failure helps to develop potent yet stable kill switches. To guide the design of robust kill switches in the agriculturally relevant strain Pseudomonas fluorescens SBW25, we present a comparison of lethality, stability, and genetic escape of eight different toxic effectors in the presence of their cognate inactivators (i.e., toxin–antitoxin modules, polymorphic exotoxin–immunity systems, restriction endonuclease–methyltransferase pair). We find that cell killing capacity and evolutionary stability are inversely correlated and dependent on the level of protection provided by the inactivator gene. Decreasing the proteolytic stability of the inactivator protein can increase cell killing capacity, but at the cost of long-term circuit stability. By comparing toxins within the same genetic context, we determine that modes of genetic escape increase with circuit complexity and are driven by toxin activity, the protective capacity of the inactivator, and the presence of mutation-prone sequences within the circuit. Here, the results of our study reveal that circuit complexity, toxin choice, inactivator stability, and DNA sequence design are powerful drivers of kill switch stability and valuable targets for optimization of biocontainment systems.
59 BASIC BIOLOGICAL SCIENCES↗
Stable Optocoupler
Circuit stabilizes current-transfer ratio (CTR) of optically coupled isolator used as linear transducer. New circuit employs feedback circuit containing second optocoupler. Circuit is inexpensive, requires little additional hardware.
Griffin, D. J.↗
Electrochemical stability of LiMF6 (M = P, As, Sb) in tetrahydrofuran and sulfolane
The electrochemical stability of LiSbF6 and LiPF6 in aprotic organic solvents has been investigated. Electrochemical studies, conductivity measurements, and open-circuit stability tests were conducted on LiSbF6 in tetrahydrofuran and sulfolane. Cyclic voltammetric studies of SbF6(-) were compared with those of AsF6(-) and PF6(-) anions. Sb(V) was reduced to Sb(III), and then to Sb(0). AsF6(-) was reduced to AsF3, while no reduction of PF6(-) was observed. The reduction products of AsF6(-) and SbF6(-) passivated the glassy carbon electrode, presumably due to LiF precipitation. Peak potentials were observed to shift in the positive direction as a function of concentration. This was accounted for on the basis of a follow-up chemical reaction.
Nanjundiah, C.↗
The Superconducting Cavity Stabilized Oscillator
Superconducting Cavity Stabilized Oscillators (SCSOs) have produced the most stable clocks to date for integration times between 10(exp 2) and 10(exp 3) seconds, achieving a fractional frequency stability of 2 x 10(exp -16) for a sampling time of 100 s. The principal contributors to cavity frequency variations are: (1) acceleration effects due to gravity and vibrations; (2) temperature variations; (3) variations in the energy stored in the cavity; and (4) noise introduced by the frequency stabilization circuit. We discuss the prospects for improvements in all these areas for both ground-based and space-based SCSOs, which may lead to SCSOs with fractional frequency stabilities below 10(exp -17). SCSOs of this frequency stability will be useful for testing fundamental physical principles.
Turneaure, J. P.↗
On infinite tensor networks, complementary recovery and type II factors
We initiate a study of local operator algebras at the boundary of infinite tensor networks, using the mathematical theory of inductive limits. In particular, we consider tensor networks in which each layer acts as a quantum code with complementary recovery, a property that features prominently in the bulk-to-boundary maps intrinsic to holographic quantum error-correcting codes. In this case, we decompose the limiting Hilbert space and the algebras of observables in a way that keeps track of the entanglement in the network. As a specific example, we describe this inductive limit for the holographic Harlow-Pastawski-Preskill-Yoshida code model and relate its algebraic and error-correction features. We find that the local algebras in this model are given by the hyperfinite type II$_\infty$ factor. Next, we discuss other networks that build upon this framework and comment on a connection between type II factors and stabilizer circuits. We conclude with a discussion of multiscale entanglement renormalization ansatz networks in which complementary recovery is broken. We argue that this breaking possibly permits a limiting type III von Neumann algebra, making them more suitable ansätze for approximating subregions of quantum field theories.
holographic dualities↗
Accelerating computing for the future electric grid (CRADA Final Report)
As a participant in the Cyclotron Road Lab-Embedded Entrepreneurship Program (LEEP), Vellex Computing, Inc. has successfully validated the "Vellex Computing Stack," a breakthrough Analog Neural Computer (ANC) specifically designed for high-performance edge optimization. This project achieved critical milestones in mixed-signal circuit stability and software-hardware co-design, directly addressing national priorities in semiconductor resiliency. The success of this work is deeply rooted in the support from the Cyclotron Road LEEP, which provided the essential "hard tech" runway—funding, mentorship, and access to Lawrence Berkeley National Laboratory’s world-class characterization facilities—allowing Vellex to overcome the "Valley of Death" often faced by deep-tech hardware startups. By leveraging LBNL’s advanced testing infrastructure, Vellex was able to rigorously benchmark the ANC architecture against state-of-the-art digital solutions, a feat that would have been resource-prohibitive independently. This collaboration has not only advanced American leadership in analog computing but has also matured Vellex’s technology to a stage ripe for private sector commercialization.
24 POWER TRANSMISSION AND DISTRIBUTION↗
Two-stage emitter follower is temperature stabilized
Two-stage temperature stabilized circuit using two transistors is described. Increase in temperature causes the base-to-emitter voltage of n-p-n transistor to become less positive whereas the base-to-emitter voltage of p-n-p transistor becomes less negative, so the temperature-induced variation in V sub 1 and V sub 2 cancel out.
Schmidt, M. H.↗
The spacecraft communications repeater
This paper describes the electrical characteristics of the waveguide components, the solid-state circuits and the traveling-wave tube used in the microwave communications repeater. The reflex-circuit method of obtaining local oscillator signals for the modulators and certain circuit stability problems are discussed.
MICROWAVE APPARATUS↗
Device for investigations at temperatures from 4.2 to 300 deg K
Metallic cryostat and electron stabilization circuit for electrical and optical studies at low temperatures
TEMPERATURE CONTROL↗
Multichannel VCO needs only one reference
Frequency stabilizing circuit controls output of multichannel microwave oscillator using passband filters and selector logic to eliminate need for separate crystal diode voltage controlled oscillator (VCO).
Masson, R. K.↗