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At least 19 records

Yet another parameter-free shape optimization method

The use of node coordinates as design variables in shape optimization offers a larger design space than computer-aided design (CAD)-based shape parameterizations. It also allows for the optimization of legacy designs, i.e., a finite element mesh from an existing design can be readily optimized to meet new performance requirements without involving a CAD model. However, it is well known that the node coordinate parameterization method is fraught with numerical difficulties, which makes it impractical to use. This has led to several of “parameter-free” shape optimization methods that seek the advantages and avoid the pitfalls of the naïve node coordinate parameterization method. These methods come in two main varieties: sensitivity filtering (or gradient smoothing) and consistent filtering. The latter is analogous to the density filter method used in topology optimization (TO). In this work, we use the PDE filter from TO and energy-based filters to implement consistent shape optimization filtering schemes easily and efficiently. Numerical experiments demonstrate that consistent methods are more robust than sensitivity filtering methods.

42 ENGINEERING↗

An algebraic method for constructing stable and consistent autoregressive filters

In this paper, we introduce an algebraic method to construct stable and consistent univariate autoregressive (AR) models of low order for filtering and predicting nonlinear turbulent signals with memory depth. By stable, we refer to the classical stability condition for the AR model. By consistent, we refer to the classical consistency constraints of Adams–Bashforth methods of order-two. One attractive feature of this algebraic method is that the model parameters can be obtained without directly knowing any training data set as opposed to many standard, regression-based parameterization methods. It takes only long-time average statistics as inputs. The proposed method provides a discretization time step interval which guarantees the existence of stable and consistent AR model and simultaneously produces the parameters for the AR models. In our numerical examples with two chaotic time series with different characteristics of decaying time scales, we find that the proposed AR models produce significantly more accurate short-term predictive skill and comparable filtering skill relative to the linear regression-based AR models. These encouraging results are robust across wide ranges of discretization times, observation times, and observation noise variances. Finally, we also find that the proposed model produces an improved short-time prediction relative to the linear regression-based AR-models in forecasting a data set that characterizes the variability of the Madden–Julian Oscillation, a dominant tropical atmospheric wave pattern.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

High Yield nTOF Spec A and NP Filter Holders Static and Seismic Analysis

The Neutron Time-of-Flight (nTOF) detectors located in the Alcove and at the North Pole (Spec A and Spec NP respectively) need filtering in the beam path to enable them to take data at NIF yields above 5MJ. The filtering consists of 12cm of filter material divided into four, 3cm thick “pucks.” The pucks are 7cm in diameter. Each puck is mounted into a rotatable stage, also called a Filter Flipper, that can bring it into and out of the beam path, see Figure 1-1. These stages are bolted onto a plate that connects the filter stages to the mounting hardware used to position them in the NIF Target Bay. The top-level filter mount assemblies will be permanently mounted in the facility; removal is possible if needed for NIF maintenance, but the design intent is for the assemblies to remain in their locations after alignment is completed.

42 ENGINEERING↗

Updated Filter Leak Frequencies for Use in Risk Assessments

Quantitative risk assessment (QRA) is highly dependent on data, leading to more robust models as new and updated data is acquired. The Hydrogen Plus Other Alternative Fuels Risk Assessment (HyRAM+) QRA capabilities include calculations of individual risk from leaks in a gaseous hydrogen facility due to the potential effects of jet fires and explosions. Leak frequencies are acquired through statistical analysis of published data from a variety of sources and industries. The filter leak frequencies in previous versions of the HyRAM+ software are substantially greater than the leak frequencies of other components, leading to QRA results for gaseous hydrogen in which filters consistently dominate the overall risk. Data that were previously used to derive the filter leak frequencies were reevaluated for applicability and additional data points were added to update the filter leak frequencies. The new frequencies are more comparable to leak frequencies for other components.

08 HYDROGEN↗

WE-F-16A-02: Design, Fabrication, and Validation of a 3D-Printed Proton Filter for Range Spreading

Purpose: To design, fabricate and test a 3D-printed filter for proton range spreading in scanned proton beams. The narrow Bragg peak in lower-energy synchrotron-based scanned proton beams can result in longer treatment times for shallow targets due to energy switching time and plan quality degradation due to minimum monitor unit limitations. A filter with variable thicknesses patterned on the same scale as the beam's lateral spot size will widen the Bragg peak. Methods: The filter consists of pyramids dimensioned to have a Gaussian distribution in thickness. The pyramids are 2.5mm wide at the base, 0.6 mm wide at the peak, 5mm tall, and are repeated in a 2.5mm pseudo-hexagonal lattice. Monte Carlo simulations of the filter in a proton beam were run using TOPAS to assess the change in depth profiles and lateral beam profiles. The prototypes were constrained to a 2.5cm diameter disk to allow for micro-CT imaging of promising prototypes. Three different 3D printers were tested. Depth-doses with and without the prototype filter were then measured in a ~70MeV proton beam using a multilayer ion chamber. Results: The simulation results were consistent with design expectations. Prototypes printed on one printer were clearly unacceptable on visual inspection. Prototypes on a second printer looked acceptable, but the micro-CT image showed unacceptable voids within the pyramids. Prototypes from the third printer appeared acceptable visually and on micro-CT imaging. Depth dose scans using the prototype from the third printer were consistent with simulation results. Bragg peak width increased by about 3x. Conclusions: A prototype 3D printer pyramid filter for range spreading was successfully designed, fabricated and tested. The filter has greater design flexibility and lower prototyping and production costs compared to traditional ridge filters. Printer and material selection played a large role in the successful development of the filter.

07 ISOTOPE AND RADIATION SOURCES↗

MEASURING THE GALAXY CLUSTER BULK FLOW FROM WMAP DATA

We have looked for bulk motions of galaxy clusters in the Wilkinson Microwave Anisotropy Probe (WMAP) seven-year data. We isolate the kinetic Sunyaev-Zeldovich (SZ) signal by filtering the WMAP Q-, V-, and W-band maps with multi-frequency matched filters that utilize the spatial properties of the kinetic SZ signal to optimize detection. We try two filters: a filter that has no spectral dependence, and a filter that utilizes the spectral properties of the kinetic and thermal SZ signals to remove the thermal SZ bias. We measure the monopole and dipole spherical harmonic coefficients of the kinetic SZ signal, as well as the l = 2-5 modes, at the locations of 736 ROSAT observed galaxy clusters. We find no significant power in the kinetic SZ signal at these multipoles with either filter, consistent with the {Lambda}CDM prediction. Our limits are a factor of {approx}3 more sensitive than the claimed bulk flow detection of Kashlinsky et al. Using simulations we estimate that in maps filtered by our matched filter with no spectral dependence there is a thermal SZ dipole that would be mistakenly measured as a bulk motion of {approx}2000-4000 km s{sup -1}. For the WMAP data, the signal-to-noise ratio obtained with the unbiased filter is almost an order of magnitude lower.

79 ASTRONOMY AND ASTROPHYSICS↗

Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel

C-type inactivation is a time-dependent process observed in many K+ channels whereby prolonged activation by an external stimulus leads to a reduction in ionic conduction. While C-type inactivation is thought to be a result of a constriction of the selectivity filter, the local dynamics of the process remain elusive. Here, we use molecular dynamics (MD) simulations of the KcsA channel to elucidate the nature of kinetically delayed activation/inactivation gating coupling. Microsecond-scale MD simulations based on the truncated form of the KcsA channel (C-terminal domain deleted) provide a first glimpse of the onset of C-type inactivation. We observe over multiple trajectories that the selectivity filter consistently undergoes a spontaneous and rapid (within 1–2 µs) transition to a constricted conformation when the intracellular activation gate is fully open, but remains in the conductive conformation when the activation gate is closed or partially open. Multidimensional umbrella sampling potential of mean force calculations and nonequilibrium voltage-driven simulations further confirm these observations. Electrophysiological measurements show that the truncated form of the KcsA channel inactivates faster and greater than full-length KcsA, which is consistent with truncated KcsA opening to a greater degree because of the absence of the C-terminal domain restraint. Together, these results imply that the observed kinetics underlying activation/inactivation gating reflect a rapid conductive-to-constricted transition of the selectivity filter that is allosterically controlled by the slow opening of the intracellular gate.

Li, Jing↗

SU-C-207-06: In Vivo Quantification of Gold Nanoparticles Using K-Edge Imaging Via Spectrum Shaping by Gold Filter

Purpose: Gold nanoparticles (AuNP) are multifunctional platforms ideal for drug delivery, targeted imaging and radiosensitization. We have investigated quantitative imaging of AuNPs using on board imager (OBI) cone beam computed tomography (CBCT). To this end, we also present, for the first time, a novel method for k-edge imaging of AuNP by filter-based spectral shaping. Methods: We used a digital 25 cm diameter water phantom, embedded with 3 cm spheres filled with AuNPs of different concentrations (0 mg/ml – 16 mg/ml). A poly-energetic X-ray spectrum of 140 kVp from a conventional X-ray tube is shaped by balanced K-edge filters to create an excess of photons right above the K-edge of gold at 80.7 keV. The filters consist of gold, tin, copper and aluminum foils. The phantom with appropriately assigned attenuation coefficients is forward projected onto a detector for each energy bin and then integrated. FKD reconstruction is performed on the integrated projections. Scatter, detector efficiency and noise are included. Results: We found that subtracting the results of two filter sets (Filter A:127 µm gold foil with 254 µm tin, 330 µm copper and 1 mm aluminum, and Filter B: 635 µm tin with 264 µm copper and 1 mm aluminum), provides substantial image contrast. The resulting filtered spectra match well below 80.7 keV, while maintaining sufficient X-ray quanta just above that. Voxel intensities of AuNP containing spheres increase linearly with AuNP concentration. K-edge imaging provides 18% more sensitivity than the tin filter alone, and 38% more sensitivity than the gold filter alone. Conclusion: We have shown that it is feasible to quantitatively detect AuNP distributions in a patient-sized phantom using clinical CBCT and K-edge spectral shaping.

60 APPLIED LIFE SCIENCES↗

A PRECISION PHOTOMETRIC COMPARISON BETWEEN SDSS-II AND CSP TYPE Ia SUPERNOVA DATA

Consistency between Carnegie Supernova Project (CSP) and SDSS-II Supernova Survey ugri measurements has been evaluated by comparing Sloan Digital Sky Survey (SDSS) and CSP photometry for nine spectroscopically confirmed Type Ia supernova observed contemporaneously by both programs. The CSP data were transformed into the SDSS photometric system. Sources of systematic uncertainty have been identified, quantified, and shown to be at or below the 0.023 mag level in all bands. When all photometry for a given band is combined, we find average magnitude differences of equal to or less than 0.011 mag in ugri, with rms scatter ranging from 0.043 to 0.077 mag. The u-band agreement is promising, with the caveat that only four of the nine supernovae are well observed in u and these four exhibit an 0.038 mag supernova-to-supernova scatter in this filter.

79 ASTRONOMY AND ASTROPHYSICS↗

Mapping the gas density with the kinematic Sunyaev-Zel’dovich and patchy screening effects: A self-consistent comparison

The secondary anisotropies of the cosmic microwave background (CMB) provide a wealth of astrophysical and cosmological information. Pairing measurements of the CMB temperature map obtained by DR5 of the Atacama Cosmology Telescope (ACT) with the imaging survey conducted by the Dark Energy Spectroscopic Instrument for the purposes of target selection, DECaLS DR9, we investigate two effects that are sensitive to the gas density 𝜏: kinematic Sunyaev-Zel’dovich (kSZ) and patchy screening or anisotropic screening (resulting from the Thomson scattering of CMB photons away from the line-of-sight by free electrons). In particular, we measure the stacked profiles of the gas density around luminous red galaxies (LRGs) at a mean redshift of 𝑧 ≈ 0.7. We detect the kSZ signal at 7.2⁢𝜎, and we find a signal at ∼ 4.1⁢𝜎 for the patchy screening estimator, which is in excess relative to the kSZ signal. We attribute this excess to contamination from CMB lensing. Here, we demonstrate the effect of lensing using 𝑁-body simulations, and we show that the screening signal is dominated by it. Accounting for lensing, our measurement places a 95% upper bound on the optical depth of the Extended DESI LRG sample of 𝜏 < 2.5 10 −4 for a mean value of the sample of 𝜏 ≈ 1.6 10 −4 . Furthermore, via hydro simulations, we show that the underlying optical depth signal measured by both effects (after removing the CMB lensing contribution) is in perfect agreement when adopting either a compensated aperture photometry (CAP) filter or a high-pass filter. Consistent with previous measurements, we see evidence for excess baryonic feedback around DESI LRGs in the patchy screening measurement. In the future, when both effects can be measured with high signal-to-noise, one can measure the amplitude ratio between them, which is proportional to the root-mean-square velocity of the host halo sample, and even place constraints on velocity-sensitive models such as modified gravity and phantom dark energy.

Astrophysical & cosmological simulations↗

A common resequencing‐based genetic marker data set for global maize diversity

SUMMARY Maize ( Zea mays ssp. mays ) populations exhibit vast ranges of genetic and phenotypic diversity. As sequencing costs have declined, an increasing number of projects have sought to measure genetic differences between and within maize populations using whole‐genome resequencing strategies, identifying millions of segregating single‐nucleotide polymorphisms (SNPs) and insertions/deletions (InDels). Unlike older genotyping strategies like microarrays and genotyping by sequencing, resequencing should, in principle, frequently identify and score common genetic variants. However, in practice, different projects frequently employ different analytical pipelines, often employ different reference genome assemblies and consistently filter for minor allele frequency within the study population. This constrains the potential to reuse and remix data on genetic diversity generated from different projects to address new biological questions in new ways. Here, we employ resequencing data from 1276 previously published maize samples and 239 newly resequenced maize samples to generate a single unified marker set of approximately 366 million segregating variants and approximately 46 million high‐confidence variants scored across crop wild relatives, landraces as well as tropical and temperate lines from different breeding eras. We demonstrate that the new variant set provides increased power to identify known causal flowering‐time genes using previously published trait data sets, as well as the potential to track changes in the frequency of functionally distinct alleles across the global distribution of modern maize.

59 BASIC BIOLOGICAL SCIENCES↗

In-orbit operation of Resolve Filter Wheel and modulated X-ray source

The Resolve soft X-ray spectrometer is a high spectral resolution microcalorimeter spectrometer for the X-ray Imaging and Spectroscopy Mission. In the beam of Resolve, there is a filter wheel containing X-ray filters. In the beam, there is also an active calibration source, the modulated X-ray source (MXS), which can provide pulsed X-rays to facilitate gain calibration. The filter wheel consists of six filter positions. Two open positions, one 55 Fe source to aid in spectrometer characterization during the commissioning phase, and three transmission filters: a neutral density filter, an optical blocking filter, and a beryllium filter. The X-ray intensity, pulse period, and pulse separation of an MXS are highly configurable. Furthermore, the switch-on time is synchronized with the spacecraft’s internal clock to give accurate start and end times of the pulses. One of the issues raised during ground testing was the susceptibility of an MXS at high voltage to ambient light. Although measures were taken to mitigate the light leak, the efficacy of those measures must be verified in orbit. Along with an overview of issues raised during ground testing, we will discuss the calibration source and the filter performance in-flight and compare with the transmission curves present in the Resolve calibration database.

X-ray Imaging and Spectroscopy Mission/Resolve↗

A broadband gamma-ray spectrometry using novel unfolding algorithms for characterization of laser wakefield-generated betatron radiation

We present a high-flux, broadband gamma-ray spectrometry capable of characterizing the betatron radiation spectrum over the photon energy range from 10 keV to 20 MeV with respect to the peak photon energy, spectral bandwidth, and unique discrimination from background radiations, using a differential filtering spectrometer and the unfolding procedure based on the Monte Carlo code GEANT4. These properties are experimentally verified by measuring betatron radiation from a cm-scale laser wakefield accelerator (LWFA) driven by a 1-PW laser, using a differential filtering spectrometer consisting of a 15-filter and image plate stack. The gamma-ray spectra were derived by unfolding the photostimulated luminescence (PSL) values recorded on the image plates, using the spectrometer response matrix modeled with the Monte Carlo code GEANT4. The accuracy of unfolded betatron radiation spectra was assessed by unfolding the test PSL data simulated with GEANT4, showing an ambiguity of less than 20% and clear discrimination from the background radiation with less than 10%. The spectral analysis of betatron radiation from laser wakefield-accelerated electron beams with energies up to 3 GeV revealed radiation spectra characterized by synchrotron radiation with the critical photon energy up to 7 MeV. The gamma-ray spectrometer and unfolding method presented here facilitate an in-depth understanding of betatron radiation from LWFA process and a novel radiation source of high-quality photon beams in the MeV regime.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

TOMOGRAPHY OF PLASMA FLOWS IN THE UPPER SOLAR CONVECTION ZONE USING TIME-DISTANCE INVERSION COMBINING RIDGE AND PHASE-SPEED FILTERING

The consistency of time-distance inversions for horizontal components of the plasma flow on supergranular scales in the upper solar convection zone is checked by comparing the results derived using two k-{omega} filtering procedures-ridge filtering and phase-speed filtering-commonly used in time-distance helioseismology. I show that both approaches result in similar flow estimates when finite-frequency sensitivity kernels are used. I further demonstrate that the performance of the inversion improves (in terms of a simultaneously better averaging kernel and a lower noise level) when the two approaches are combined together in one inversion. Using the combined inversion, I invert for horizontal flows in the upper 10 Mm of the solar convection zone. The flows connected with supergranulation seem to be coherent only for the top {approx}5 Mm; deeper down there is a hint of change of the convection scales toward structures larger than supergranules.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Boundary-consistent B-spline filtering schemes and application to high-fidelity simulations of turbulence

A filtering operation, based on B-spline discretizations, is introduced to target weakly growing mesh-scale oscillations that can arise in high-fidelity turbulence simulations. This is a spectral regularization that can be described using the singular values of a banded matrix operator, with the filtering strength set by a scalar- or vector-valued penalty parameter. The penalty parameter can be specified though it can also be advantageously selected to minimize the generalized cross validation (GCV) measure of distance between the pre- and post-filtered solutions. Efficient algorithms are developed to compute both the scalar and vector penalty parameters. The B-spline filter has a sharper localization to high-wavenumber than compact or explicit filters of the same stencil width and is demonstrated for solutions of the Burgers' equation, decaying Burgers' turbulence, and compressible Navier–Stokes turbulent channel flow. Furthermore, these simulations confirm the scheme's numerical stability and ability to narrowly target the high wavenumber components of numerical solutions. An advantage over finite-difference filters is that these B-spline filters are stable on bounded domains and even preserve formal order of accuracy.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Development of a Model Correlating Axial HEPA Filter Performance Between Elevated and Standard Conditions

The ASME AG-1 Code specifies minimum rated airflow based on standard cubic feet per minute (SCFM) for axial high efficiency particulate air (HEPA) filters and actual cubic feet per minute (ACFM) for radial HEPA filters with corresponding maximum pressure drop. A quantitative analysis can be performed to demonstrate the variation in filter efficiency and develop a correlation of performance between axial filters subjected to ACFM and SCFM. This study illustrates the variation in filter efficiency of axial HEPA filters subjected to ACFM and SCFM flow rate conditions at varying atmospheric pressures. It also presents the methods used to calculate correction factors to convert filter efficiency and pressure drop from elevated to standard conditions. The Axial Large Scale Test Stand (ALSTS) in the Institute for Clean Energy Technology (ICET) at Mississippi State University has been utilized to control aerosol concentration, flowrate, atmospheric pressure, relative humidity, and temperature. The filter test matrix consists of axial HEPA filters rated at 1,000 and 1,500 CFM with varying filter pack types. Each filter is subjected to varying pressures of 14.70 psi, 13.55 psi, 12.40 psi, and 11.25 psi, temperatures of 70 deg. F, 110 deg. F, and 150 deg. F, and relative humidities of 50% and 80%, resulting in twenty-four unique testing points. The corresponding SCFM flow rates are computed for each point in order to form a comparison. Evaluation of the effects of designating ACFM or SCFM will be based upon the filter efficiencies of generated Dioctyl Phthalate (DOP) particles at a diameter of 0.3 micrometers. The results show filter efficiency decreasing as atmospheric pressure decreases due to increased filter face velocity. A correlation model is developed to convert filter efficiency and pressure drop at elevated conditions to those of standard pressure, relative humidity, and temperature.

42 ENGINEERING↗

High resolution on-chip optical filter array based on double subwavelength grating reflectors

An optical filter array consisting of vertical narrow-band Fabry-Pèrot (FP) resonators formed by two highly reflective high contrast subwavelength grating mirrors is reported. The filters are designed to cover a wide range of operation wavelengths ( Δλ/λ=5%) just by changing the in-plane grating parameters while the device thickness is maintained constant. In conclusion, operation in the telecom band with transmission efficiencies greater than 40% and quality factors greater than 1,000 are measured experimentally for filters fabricated on the same substrate.

36 MATERIALS SCIENCE↗

A micromorphic filter for determining stress and deformation measures from direct numerical simulations of lower length scale behavior

A micromorphic filter is presented for the extraction of stress and deformation measures from underlying direct numerical simulation (DNS) of microstructural mechanical response. The filter is consistent with the micromorphic continuum theory of Eringen and Suhubi (1964), and allows the interrogation of a DNS to generate higher order constitutive models. The filter adopts aspects of the overlap coupling techniques for atomistic-continuum scale-bridging in order to update the nodal degrees of freedom of the finite-element-based filter. Here, two methods for the extraction of quantities of interest from the underlying DNS are presented. The first is a least squares fitting technique which is appropriate for finite-element-style macro-scale domains, and the second is a variationally based approach which generalizes the method to any macro-scale domain which has a variational form. No restrictions on the form of the micro-scale simulation are inherent to the approach, provided that the required quantities (stress, position, etc.) can be provided. The filter is applied to a simple homogeneous medium undergoing homogeneous deformation to demonstrate the recovery of a classical continuum response, what we call the null case. We then apply the framework to the same homogeneous medium with a central and edge penny-shaped crack to show micromorphic effects. We demonstrate that varying the size of the filter causes the micromorphic behaviors to arise and then dissipate as the filter becomes smaller than the crack's length scale. Additionally we show the effect of filter size on a chiral element network along with a plate perforated with evenly spaced and perturbed holes through the thickness. The micromorphic effects are shown to be present for the chiral elements under any loading but become most pronounced when a single element is located within each averaging domain. Micromorphic effects become pronounced for the plate upon the onset of localization.

97 MATHEMATICS AND COMPUTING↗