Search NASA⌕ Search

SEARCH · Search NASA

Results for “network alignment”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 records

MiNAA: Microbiome Network Alignment Algorithm

A microbial network is a mathematical representation of a microbial community where nodes represent microbes and edges represent interactions. It is well-recognized that microbes are among the main drivers of biological phenotypes in soil, plants, and animals alike, and thus, their study has vast implications for soil, plant and human health. In particular, recognizing the microbial, environmental, and agricultural factors that drive plant and soil phenotypes is crucial to comprehend processes connected to plant and soil health, to identify global practices of sustainable agriculture, as well as to predict plant and soil responses to environmental perturbations such as climate change. The adaptability of microbes to thrive in every environment poses challenges for scientists who try to understand their communities. Indeed, two microbial communities with the exact same players can interact differently depending on the environmental conditions. It is thus desirable to identify commonalities and differences on two microbial networks, hence the need for computational tools that can match (or align) them.

97 MATHEMATICS AND COMPUTING↗

Parallel access alignment network with barrel switch implementation for d-ordered vector elements

An alignment network between N parallel data input ports and N parallel data outputs includes a first and a second barrel switch. The first barrel switch fed by the N parallel input ports shifts the N outputs thereof and in turn feeds the N-1 input data paths of the second barrel switch according to the relationship X=k.sup.y modulo N wherein x represents the output data path ordering of the first barrel switch, y represents the input data path ordering of the second barrel switch, and k equals a primitive root of the number N. The zero (0) ordered output data path of the first barrel switch is fed directly to the zero ordered output port. The N-1 output data paths of the second barrel switch are connected to the N output ports in the reverse ordering of the connections between the output data paths of the first barrel switch and the input data paths of the second barrel switch. The second switch is controlled by a value m, which in the preferred embodiment is produced at the output of a ROM addressed by the value d wherein d represents the incremental spacing or distance between data elements to be accessed from the N input ports, and m is generated therefrom according to the relationship d=k.sup.m modulo N.

Barnes, George H.↗

Neural-network-directed alignment of optical systems using the laser-beam spatial filter as an example

This report describes an effort at NASA Lewis Research Center to use artificial neural networks to automate the alignment and control of optical measurement systems. Specifically, it addresses the use of commercially available neural network software and hardware to direct alignments of the common laser-beam-smoothing spatial filter. The report presents a general approach for designing alignment records and combining these into training sets to teach optical alignment functions to neural networks and discusses the use of these training sets to train several types of neural networks. Neural network configurations used include the adaptive resonance network, the back-propagation-trained network, and the counter-propagation network. This work shows that neural networks can be used to produce robust sequencers. These sequencers can learn by example to execute the step-by-step procedures of optical alignment and also can learn adaptively to correct for environmentally induced misalignment. The long-range objective is to use neural networks to automate the alignment and operation of optical measurement systems in remote, harsh, or dangerous aerospace environments. This work also shows that when neural networks are trained by a human operator, training sets should be recorded, training should be executed, and testing should be done in a manner that does not depend on intellectual judgments of the human operator.

Decker, Arthur J.↗

Disruption of an Aligned Dendritic Network by Bubbles During Re-Melting in a Microgravity Environment

The quiescent Microgravity environment can be quite dynamic. Thermocapillary flow about "large" static bubbles on the order of 1mm in diameter was easily observed by following smaller tracer bubbles. The bubble induced flow was seen to disrupt a large dendritic array, effectively distributing free branches about the solid-liquid interface. "Small" dynamic bubbles were observed to travel at fast velocities through the mushy zone with the implication of bringing/detaching/redistributing dendrite arm fragments at the solid-liquid interface. Large and small bubbles effectively re-orient/re-distribute dendrite branches/arms/fragments at the solid liquid interface. Subsequent initiation of controlled directional solidification results in growth of dendrites having random orientations which significantly compromises the desired science.

Grugel, Richard N.↗

4D Multimodal Co-attention Fusion Network with Latent Contrastive Alignment for Alzheimer’s Diagnosis

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer’s disease (AD) through synergistic integration of neuroimaging data (e.g., sMRI, fMRI) with tabular data (e.g., behavioral and cognitive tests). However, the intrinsic heterogeneity across modalities (e.g., 4D spatiotemporal fMRI dynamics vs. 3D anatomical sMRI structure) presents critical challenges for discriminative feature fusion, often leading to information loss or biased fusion. To bridge this gap, we propose M2M-AlignNet: a multimodal co-attention network with latent alignment for early AD diagnosis using sMRI and fMRI. At the core of our approach is a multi-patch-to-multi-patch (M2M) contrastive loss function that quantifies and reduces representational discrepancies via weighted patch correspondence, explicitly aligning fMRI components across brain regions with their sMRI structural substrates without one-to-one constraints. Additionally, we propose a latent-as-query co-attention module to autonomously discover fusion patterns, circumventing modality prioritization biases while minimizing feature redundancy. We conduct extensive experiments to confirm the effectiveness of our method and highlight the correspondence between fMRI and sMRI as AD biomarkers.

Wei, Yuxiang [Georgia Institute of Technology]↗

An interaction network in the polymerase active site is a prerequisite for Watson-Crick base pairing in Pol γ

The replication accuracy of DNA polymerase gamma (Pol γ) is essential for mitochondrial genome integrity. Mutation of human Pol γ arginine-853 has been linked to neurological diseases. Although not a catalytic residue, Pol γ arginine-853 mutants are void of polymerase activity. To identify the structural basis for the disease, we determined a crystal structure of the Pol γ mutant ternary complex with correct incoming nucleotide 2'-deoxycytidine 5'-triphosphate (dCTP). Opposite to the wild type that undergoes open-to-closed conformational changes when bound to a correct nucleotide that is essential for forming a catalytically competent active site, the mutant complex failed to undergo the conformational change, and the dCTP did not base pair with its Watson-Crick complementary templating residue. Our studies revealed that arginine-853 coordinates an interaction network that aligns the 3'-end of primer and dCTP with the catalytic residues. Disruption of the network precludes the formation of Watson-Crick base pairing and closing of the active site, resulting in an inactive polymerase.

59 BASIC BIOLOGICAL SCIENCES↗

Countering Weapons of Mass Destruction (CWMD) Device Cybersecurity Characterization Process and Profile

Countering Weapons of Mass Destruction (CWMD) recognizes that threats in the cyberspace domain continue to grow, which requires CWMD devices and supporting systems to be both cybersecure (ability to protect or defend from cyber-attacks) and resilient (ability to maintain required capability in the face of adversity) to cyber threats. The CWMD cybersecurity characterization approach in this document supports existing cyber resilience activities within the Acquisition Lifecycle Framework. Similarly, this process supports existing Department of Homeland Security Cyber Resilience Test and Evaluation activities, which consist of iterative processes, starting at the initiation of system acquisition and continuing throughout the entire device and system life cycle. Cyber resilience is the ability of an information system to continue to operate while under attack, even if in a degraded or debilitated state,1 and to rapidly recover operational capabilities for essential functions after a successful attack.2 The goal of the security characterization task for CWMD is to support the development of a CBRN device-dependent profile that aligns with device network capabilities and maps to recommended security controls to create a characterization security profile impact levels. The impact levels for CWMD devices should be characterized as Low (L), Moderate (M), High (H) to align with the low, moderate, high control baselines. To estimate the impact levels, the device’s security-related attributes are translated into the security objectives: Confidentiality (C), Integrity (I), and Availability (A), known as the CIA triad. The potential impact for each device can be L, M, H, for devices that connect and transmit different types of data and may have different impact levels. National Institute of Standards and Technology Federal Information Processing Standards Publication 199 states, “the potential impact values assigned to the respective security objectives shall be the highest value from among those security categories that have been determined for each type of information resident on the information system.”3 As CWMD is determining the cybersecurity impact levels of CBRN devices based on network connections and data transfers, the impact levels are aligned with the associated attributes of network connections and communications. For example, if the device system is connected to a wireless network and transmits different data types based on the confidentiality of the data, the highest impact value for each security objective should represent the device’s CIA impact level. This document is intended to be used by test managers, test team, and program managers.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗

ecospec v0.1.0

Bespoke software for segmenting plants in ecoFABs to monitor growth and health. Contains python libraries for image alignment, training neural networks and running inference.

Zwart, PetrusH [Lawrence Berkeley National Laborat↗

Solar electric propulsion system evaluation

Solar electric propulsion system performance consisting of thrustors with thrust vector aligning actuators, switching network and flight type power conditioner

Costogue, E. N.↗

Self-Aligning Optical Measurement Systems

The paper discusses how to teach a system of neural networks to respond to the alignment clues used by a human operator in performing routine, initial alignments. A paradigm is proposed for automating the alignment of the components of optical measurement systems. The paradigm which was tested on a spatial filter has proved to be successful for optical alignment.

Decker, Arthur J.↗

Neural nets for aligning optical components in harsh environments: Beam smoothing spatial filter as an example

The goal is to develop an approach to automating the alignment and adjustment of optical measurement, visualization, inspection, and control systems. Classical controls, expert systems, and neural networks are three approaches to automating the alignment of an optical system. Neural networks were chosen for this project and the judgements that led to this decision are presented. Neural networks were used to automate the alignment of the ubiquitous laser-beam-smoothing spatial filter. The results and future plans of the project are presented.

Decker, Arthur J.↗

Sn-InAs Nanowire Shadow-Defined Josephson Junctions

Hybrid superconductor–semiconductor platforms are foundational to advancing quantum information technologies, motivating the integration of materials with clean interfaces, robust superconductivity, and scalable architectures. Here, in this work, we report the synthesis and analysis of inclined InAs nanowires, conformally coated with β-Sn shells. These nanowires extend in opposite in-plane directions, forming a self-aligned, criss-cross network. This enables the deterministic formation of nanowire-shadow Josephson junctions through angle-controlled, low-temperature Sn deposition. Structural characterization shows uniform polycrystalline β-Sn shells forming a sharp, diffusion-free interface with InAs. Low-temperature transport measurements reveal a hard induced superconducting gap ≈ 600 μeV, switching currents up to ≈ 500 nA, and parallel magnetic field resilience beyond 1T. These results establish β-Sn/InAs nanowire networks as a promising platform for superconducting qubits, low-noise microwave devices, and the exploration of exotic superconducting phases including triplet pairing and topological superconductivity.

B-Sn↗

Gene-Metabolite Association Prediction with Interactive Knowledge Transfer Enhanced Graph for Metabolite Production

Identifying gene targets for enhancing metabolite production in metabolic engineering is challenging due to the vast research literature and the approximation in genome-scale metabolic model (GEM) simulations. Here, to address this, we propose the Gene-Metabolite Association Prediction task, which automates gene discovery for given metabolite-gene pairs, accompanied by a benchmark dataset of 2474 metabolites and 1947 genes for Saccharomyces cerevisiae (SC) and Issatchenkia orientalis (IO). This task is complicated by incomplete metabolic graphs and metabolic heterogeneity. We introduce an Interactive Knowledge Transfer mechanism based on Metabolism Graphs (IKT4Meta) to enhance prediction accuracy by integrating cross-metabolism knowledge. Using Pretrained Language Models (PLMs) to generate inter-graph links mitigates heterogeneity issues, while intra-graph links are propagated via these anchors. Gene-metabolite predictions are then performed on the enriched graphs integrating multiple microorganisms’ knowledge. Experiments show that IKT4Meta outperforms baselines by up to 12.3% in link prediction.

59 BASIC BIOLOGICAL SCIENCES↗

Discrete Wavelength-Locked External Cavity Laser

A prototype improved external cavity laser (ECL) was demonstrated in the second phase of a continuing effort to develop wavelength-agile lasers for fiber-optic communications and trace-gas-sensing applications. This laser is designed to offer next-generation performance for incorporation into fiber-optic networks. By eliminating several optical components and simplifying others used in prior designs, the design of this laser reduces costs, making lasers of this type very competitive in a price-sensitive market. Diode lasers have become enabling devices for fiber optic networks because of their cost, compactness, and spectral properties. ECLs built around diode laser gain elements further enhance capabilities by virtue of their excellent spectral properties with significantly increased (relative to prior lasers) wavelength tuning ranges. It is essential to exploit the increased spectral coverage of ECLs while simultaneously insuring that they operate only at precisely defined communication channels (wavelengths). Heretofore, this requirement has typically been satisfied through incorporation of add-in optical components that lock the ECL output wavelengths to these specific channels. Such add-in components contribute substantially to the costs of ECL lasers to be used as sources for optical communication networks. Furthermore, the optical alignment of these components, needed to attain the required wavelength precision, is a non-trivial task and can contribute substantially to production costs. The design of the present improved ECL differs significantly from the designs of prior ECLs. The present design relies on inherent features of components already included within an ECL, with slight modifications so that these components perform their normal functions while simultaneously effecting locking to the required discrete wavelengths. Hence, add-in optical components and the associated cost of alignment can be eliminated. The figure shows the locking feedback signal, and the frequency locking achieved by use of this signal, as a mirror is tilted through a range of angles to tune the ECL through 48 channels. The data for the frequency plot were obtained, simultaneously with the data for the locking-signal plot, by using a scanning Michelson interferometer to precisely determine the ECL wavelength (and, hence, frequency). Given the ability of the Michelson interferometer to obtain highly precise readings, the frequency plot can be taken to be a reliable indication of single-mode operation. The discontinuities in the frequency plot signify the switching of the ECL between channels; in other words, they indicate tuning with locking to discrete frequencies. The peaks of the feedbacklocking signal correspond to the centers, or near centers, of the mirror angle scan through the corresponding channels. Thus, it is clear that when the feedback-locking signal is at a local maximum, the ECL is operating at single frequency at or near the middle frequency of the selected channel. This is all that is required for precisely locking the ECL output wavelength. The locking is achieved without additional external optical components.

Pilgrim, Jeffrey S.↗

Hi-C2.1 Observations of Solar Jetlets at Edges of Network Lanes

We present high resolution (0.2”) high cadence (5s) extreme ultraviolet (EUV) observations of small-­scale jetlet-­like features and spicule-­like features observed with NASA’s High-­resolution Coronal Imager2.1 (Hi-C) during its 5‐min observing span. We investigate the magnetic setting of 4 on-disk jetlets and 2 on-­disk spicules by using high resolution 172A images from Hi-­‐C and EUV images from Solar Dynamics Observatory (SDO)/Atmospheric Imaging Assembly (AIA) and line-­of-­sight magnetograms from SDO/Helioseismic and Magnetic Imager (HMI). The jetlets and spicules are at edges of magnetic network lanes. From magnetograms co-­aligned with the Hi-­C and AIA images, we find that the jetlets stem from sites of likely flux cancelation between merging majority-polarity and weaker minority-­polarity flux, but in contrast to larger jetlets observed by IRIS some do not show obvious enhanced brightenings at their base. Based on the similarity of these observations of approx. 4 obvious Hi-­C small jetlets with our previous observations of 10 IRIS larger jetlets and approx. 30 coronal jets in quiet regions and coronal holes, we infer that flux cancelation is probably the essential process in the buildup and triggering of jetlets. Our observations suggest that network jetlet eruptions, large and small, are small-scale analogs of both larger-­scale coronal jet eruptions and the still-­larger-­scale eruptions that makemajor CMEs. For simplicitywe will use termjetlets for jetlet-­like features and spicules for spicule-­like features.

Panesar, Navdeep K.↗