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Power and Signal Integrity Findings in a FPGA Layout for an Aerospace Application
Design principles concerning the use of FPGA are of particular importance in aerospace applications since the neglect of such design principles can cause catastrophic effects in aerospace system, as it will be explained in this paper. FPGA design rules such as power conditioning and signal integrity for properly interfacing high speed FPGA with its interface circuits are discussed in this paper as it relates to aerospace systems. Signal integrity to avoid crosstalk within a FPGA has not been a great concern because most of the attention over the years had been on signal integrity at the PCB level. However, this paper shows a real example of crosstalk within a FPGA in an aerospace application.
Optimum Linear Filtering of an Integrated Signal in White Noise
Linear filtering of integrated signal observed in white noise
Preemptive signal integrity control
Techniques are provided herein for pre-emptively reinforcing one or more buses of a computing device against the effects of signal noise that could cause a reduction in signal integrity. The techniques generally include detecting an event (or “trigger”) that would tend to indicate that a reduction in signal integrity will occur, examining a reinforcement action policy and system status to determine what reinforcement action to take, and performing the reinforcement action.
Optimum linear filtering of an integrated signal in white noise.
Optimum linear filtering of integrated signal in white noise, deriving expression for minimum mean square error
Differential roles of kinetic on- and off-rates in T-cell receptor signal integration revealed with a modified Fab’-DNA ligand
Antibody-derived T-cell receptor (TCR) agonists are commonly used to activate T cells. While antibodies can trigger TCRs regardless of clonotype, they bypass native T cell signal integration mechanisms that rely on monovalent, membrane-associated, and relatively weakly binding ligand in the context of cellular adhesion. Commonly used antibodies and their derivatives bind much more strongly than native peptide major histocompatibility complex (pMHC) ligands bind their cognate TCRs. Because ligand dwell time is a critical parameter that tightly correlates with physiological function of the TCR signaling system, there is a general need, both in research and therapeutics, for universal TCR ligands with controlled kinetic binding parameters. To this end, we have introduced point mutations into recombinantly expressed α-TCRβ H57 Fab to modulate the dwell time of monovalent Fab binding to TCR. When tethered to a supported lipid bilayer via DNA complementation, these monovalent Fab’-DNA ligands activate T cells with potencies well-correlated with their TCR binding dwell time. Single-molecule tracking studies in live T cells reveal that individual binding events between Fab'-DNA ligands and TCRs elicit local signaling responses closely resembling native pMHC. The unique combination of high on- and off-rates of the H57 R97L mutant enables direct observations of cooperative interplay between ligand binding and TCR-proximal condensation of the linker for activation of T cells, which is not readily visualized with pMHC. This work provides insights into how T cells integrate kinetic information from TCR ligands and introduces a method to develop affinity panels for polyclonal T cells, such as cells from a human patient.
Non-equilibrium signal integration in hydrogels
Abstract Materials that perform complex chemical signal processing are ubiquitous in living systems. Their synthetic analogs would transform developments in biomedicine, catalysis, and many other areas. By drawing inspiration from biological signaling dynamics, we show how simple hydrogels have a previously untapped capacity for non-equilibrium chemical signal processing and integration. Using a common polyacrylic acid hydrogel, with divalent cations and acid as representative stimuli, we demonstrate the emergence of non-monotonic osmosis-driven spikes and waves of expansion/contraction, as well as traveling color waves. These distinct responses emerge from different combinations of rates and sequences of arriving stimuli. A non-equilibrium continuum theory we developed quantitatively captures the non-monotonic osmosis-driven deformation waves and determines the onset of their emergence in terms of the input parameters. These results suggest that simple hydrogels, already built into numerous systems, have a much larger sensing space than currently employed.
Signal-to-noise ratio estimating by taking ratio of mean and standard deviation of integrated signal samples Patent
Automatic estimation of signal to noise ratio and other parameters in signal communication systems
Analog signal integration and reconstruction system Patent
Data acquisition system for converting displayed analog signal to digital values
A Study of Integrated Signal and Power Transfer for Compact Isolated SiC MOSFET Gate-Drivers
This work discusses a novel set of alternate implementations of isolated gate driver circuits for power electronic transistors. The proposed topologies for the driver have been designed specifically for SiC power MOSFET. Three different solutions are discussed, all of them providing the required gate turn-on and turn-off command signal with galvanic isolation, but also supplying power to the secondary side of the driver by means of magnetic transformers. The resulting solutions, all of them implemented with simple circuitry, enable the integration of the driver into the power cell, allowing for theoretical higher power density values in the final system. The principle of operation of the different solutions is discussed, and then the main relevant implementation details are presented. After that, the operation of the circuits is demonstrated experimentally, by testing a set of prototypes of these drivers. This provides a comprehensive design example that assesses the feasibility of the proposed solutions. Finally, the main results of the performance of the three gate drivers, on an SiC MOSFET-based prototype are presented and compared.
Proportionality between Doppler noise and integrated signal path electron density validated by differenced S-X range
Observations of Viking differenced S-band/X-band (S-X) range are shown to correlate strongly with Viking Doppler noise. A ratio of proportionality between downlink S-band plasma-induced range error and two-way Doppler noise is calculated. A new parameter (similar to the parameter epsilon which defines the ratio of local electron density fluctuations to mean electron density) is defined as a function of observed data sample interval (Tau) where the time-scale of the observations is 15 Tau. This parameter is interpreted to yield the ratio of net observed phase (or electron density) fluctuations to integrated electron density (in RMS meters/meter). Using this parameter and the thin phase-changing screen approximation, a value for the scale size L is calculated. To be consistent with Doppler noise observations, it is seen necessary for L to be proportional to closest approach distance a, and a strong function of the observed data sample interval, and hence the time-scale of the observations.
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
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Improvements of readout signal integrity in mid-infrared superconducting nanowire single-photon detectors
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The 1976 Helios and Pioneer solar conjunctions-continuing corroboration of the link between Doppler noise and integrated signal path electron density
Observed Doppler noise (rms phase jitter) from the 1976 solar conjunctions of the Helios 1 and 2 and the Pioneer 10 and 11 spacecraft was processed with a recently developed Doppler noise model ISEDB. Good agreement is obtained between the observed data and the model. Correlation is shown between deviations from the ISEDB model and sunspot activity, but it is insufficient to be modeled. Correlation is also shown between ISEDB model deviations for (spacecraft) signal paths on the same side of the sun.
Water Capture Device Signal Integration Board
I am a junior in electrical engineering at Arizona State University, and this is my second internship at Johnson Space Center. I am an intern in the Command and Data Handling Branch of Avionics Division (EV2), my previous internship was also in EV2. During my previous internship I was assigned to the Water Capture Device payload, where I designed a prototype circuit board for the electronics system of the payload. For this internship, I have come back to the Water Capture Device project to further the work on the electronics design I completed previously. The Water Capture Device is an experimental payload to test the functionality of two different phase separators aboard the International Space Station (ISS). A phase separator sits downstream of a condensing heat exchanger (CHX) and separates the water from the air particles for environmental control on the ISS. With changing CHX technology, new phase separators are required. The goal of the project is to develop a test bed for the two phase separators to determine the best solution.
Fiber Optic Network Signal Integrity Analyzer
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Fiber Optic Network Signal Integrity Analyzer
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