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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Intraperitoneal injection of histones and other polypeptides into adrenalectomized mice increases hepatic tyrosine-alpha-ketaglutarate transaminase and tryptophan pyrolase activity
Tyrosine transaminase activity estimation by radioactive isotopic assay method, discussing application to rat liver and other organs
Brain norepinephrine effect on daily rhythmic changes in activity of tyrosine transaminase in livers of starved adrenalectomized rats
Hepatic tyrosine transaminase rhythm in rats under various conditions of lighting, food consumption and dietary protein content
Hepatic polysome profiles and tyrosine transaminase activity daily rhythms in rats, studying dietary protein role
Amino acid metabolism time dependent variations, studying tyrosine transaminase rhythm in rat liver
Dietary intake and adrenal cortex effects on diurnal rhythm of hepatic tyrosine transaminase activity and adrenal corticosterone content in rats
Problems in collecting and shipping human sera for clinical chemical analyses affect their stability and require proper preservation methods. It is shown that glutamic pyruvate transaminase is very unstable and serum cannot be shipped unless the shipping time is carefully controlled and is less than two days under refrigeration. A limit of four days handling time and avoidance of light exposure are required in bilirubin testing of specimens. Addition of 11 mg of a 10 to 1 mixture of finely powdered sodium fluoride and thymol per ml of blood to preserve specimen stability en route to a central laboratory prevents glycolysis. A citrate buffer at pH 6.2 in serum to be tested for alkaline phosphatase lessens decline at room temperature.
To test the husbandry capabilities of the Research Animal Holding Facility (RAHF) during space flight, 24 male rats were flown on Spacelab 3 for 7 days. Twelve large rats (400 g, LF), 5 of which had telemetry devices implanted (IF), and 12 small rats (200 g, SF) were housed in the RAHF. Examination 3 hr after landing (R + 3) revealed the rats to be free of injury, well nourished, and stained with urine. At R + 10 the rats were lethargic and atonic with hyperemia of the extremities and well groomed except for a middorsal area stained with urine and food. Both LF and SF rats showed weight gains comparable to their IG controls; IF rats grew less than controls. Food and water consumption were similar for flight and control groups. Plasma concentrations of total protein, sodium, albumin and creatinine did not differ between flight and control groups. LF and SF rats had elevated plasma glucose, and SF rats had increased blood urea nitrogen, potassium and glutamic pyruvic transaminase. These observations indicate that rats maintained in the RAHF were healthy, well nourished and experienced minimal stress; physiological changes in the rats can thus be attributed to the effects of space flight.