Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth
Abstract not provided
Murphy, Megan K↗
Engineering topics
Boliar, S.
Publications and source records attributed to Boliar, S..
Sequential exposure to specific antibody escape mutations may program neutralization breadth during subtype A HIV-1 infection
Mechanisms that expand the otherwise narrow neutralization capacity observed during early HIV-1 infection are currently undefined, but multiple lines of evidence suggest that the ability to elicit broad and potent neutralizing antibodies (nAbs) via vaccination could increase the protective efficacy of immunization.
59 BASIC BIOLOGICAL SCIENCES↗