Alternative Approach to Sequence-Specific Recognition of DNA: Cooperative Stacking of Dication Dimers─Sensitivity to Compound Curvature, Aromatic Structure, and DNA Sequence
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Biochemistry & Molecular Biology↗
Engineering topics
Publications and source records attributed to Ogbonna, Edwin.
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The heterocylic diamidine DB2447 recognizes a single GC base pair in the minor groove of a mixed DNA sequence. The DNA is stabilized by a PU.1 protein bound to the major groove.