DOE OSTI · 2581997
Single GC base pair recognition by a heterocyclic diamidine: structures, affinities, and dynamics
Abstract
The heterocylic diamidine DB2447 recognizes a single GC base pair in the minor groove of a mixed DNA sequence. The DNA is stabilized by a PU.1 protein bound to the major groove.
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Ogbonna, Edwin, Terrell, J., Paul, Ananya (ORCID:0000000345923442), Farahat, Abdelbasset, Poon, Gregory (ORCID:0000000151079458), Boykin, David, Wilson, W. (ORCID:0000000152255089). 2024-01-01. Single GC base pair recognition by a heterocyclic diamidine: structures, affinities, and dynamics. https://doi.org/10.1039/d4ra05957c
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