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NASA NTRS · 20040142008

Calcium-binding proteins and development

Beckingham, K.·Lu, A. Q.·Andruss, B. F.·McIntire, L. V.
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Abstract

The known roles for calcium-binding proteins in developmental signaling pathways are reviewed. Current information on the calcium-binding characteristics of three classes of cell-surface developmental signaling proteins (EGF-domain proteins, cadherins and integrins) is presented together with an overview of the intracellular pathways downstream of these surface receptors. The developmental roles delineated to date for the universal intracellular calcium sensor, calmodulin, and its targets, and for calcium-binding regulators of the cytoskeleton are also reviewed.

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ReviewReview, AcademicNASA Discipline Cell BiologyNon-NASA CenterEmbryonic Induction/physiologySignal Transduction/physiologyCalcium-Binding Proteins/chemistry/metabolismEmbryo and Fetal Development/physiologySupport, U.S. Gov't, P.H.SSupport, U.S. Gov't, Non-P.H.SIntegrins/chemistry/physiologyModels, MolecularAnimalsProtein ConformationSupport, Non-U.S. Gov'tCadherins/chemistry/metabolismDrosophilaHumanEpidermal Growth Factor/chemistry

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Beckingham, K., Lu, A. Q., Andruss, B. F., McIntire, L. V.. 1998-12-01. Calcium-binding proteins and development. https://ntrs.nasa.gov/citations/20040142008

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