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DOE OSTI · 1866659

Engineering lanmodulin's selectivity for actinides over lanthanides by controlling solvent coordination and second-sphere interactions

Mattocks, Joseph A.·Cotruvo, Joseph A.·Deblonde, Gauthier J. -P.
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Abstract

Nature’s most potent protein for f-elements, lanmodulin, relies on subtle first-sphere/second-sphere interactions to bind metal ions. Dissecting lanmodulin’s binding mechanism yielded variants with enhanced actinide/lanthanide selectivity.

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38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY

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Mattocks, Joseph A., Cotruvo, Joseph A., Deblonde, Gauthier J. -P.. 2022-05-25. Engineering lanmodulin's selectivity for actinides over lanthanides by controlling solvent coordination and second-sphere interactions. https://doi.org/10.1039/d2sc01261h

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