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DOE OSTI · 2009031

Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in Escherichia coli

Webber, Lucas C.·Anderson, Lindsey N.·Paraiso, Ines L.·Metz, Thomas O.·Bradley, Ryan·Stevens, Jan F.·Wright, Aaron T.
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Abstract

Xanthohumol, the principle prenylflavonoid found in hops ( Humulus lupulus ) and a reported anti-inflammatory agent, has great potential for pharmaceutical interventions related to inflammatory disorders in the gut.

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37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRYactivity-based protein profilinganti-inflammatory mechanismsflavonoid metabolismhuman gut microbiomemass spectrometryprotein-protein interactionsproteomicsxanthohumol

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Webber, Lucas C., Anderson, Lindsey N., Paraiso, Ines L., Metz, Thomas O., Bradley, Ryan, Stevens, Jan F., Wright, Aaron T.. 2023-10-04. Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in Escherichia coli. https://doi.org/10.1039/d3ra05296f

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