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The United States Department of Energy and National Institutes of Health Collaboration: Medical Care Advances by Discovery in Radiation Detection

A National Institutes of Health (NIH) and U.S. Department of Energy (DOE) Office of Science virtual workshop on shared general topics was held in July of 2021 and reported on in this publication in January of 2023. Following the inaugural 2021 joint meeting representatives from the DOE Office of Science and NIH met to discuss organizing a second joint workshop that would concentrate on radiation detection to bring together teams from both agencies and their grantee populations to stimulate collaboration and efficiency. To meet this scientific mission within the NIH and DOE radiation detection space, the organizers assembled workshop sessions covering the state–of–the–art in cameras, detectors, and sensors for radiation external and internal (diagnostic and therapeutic) to human, data acquisition and electronics, image reconstruction and processing, and the application of artificial intelligence. NIH and DOE are committed to continuing the process of convening a joint workshop every 12–24 months. This Special Report recaps the findings of this second workshop. Beyond showing only the innovations and areas of success, important gaps in our knowledge were defined and presented. Finally, we summarize by defining four areas of greatest opportunity and need that emerged from the unique, dynamic dialogue the in–person workshop provided the attendees.

62 RADIOLOGY AND NUCLEAR MEDICINE

Strategies for Revitalizing Organizations: Regaining the Competitive Edge

During the last decade, the United States has lost competitive stature in the world. Challenged daily by a technically sophisticated and vitalized global economy, industry and Government are examining quality and productivity initiatives with which to meet the foreign competitive challenge. At stake are our quality of life and our standard of living for the remainder of this century and beyond. Being competitive is an ongoing process, tuned to an awareness and understanding of the dynamics of the world marketplace and to the changing nature of the work environment. Solutions to America's quality and productivity problems do not exist independently within any organization or industry or at any given level of society. Success depends on commitment, partnership, meshing of goals and responsibilities, mutual respect and understanding, and a desire to be first. A change in organizational management culture is required. Traditional authoritarian management practices must give way to enlightened leadership initiatives that stress employee involvement and participation. There must be a lessening of adversarial relationships between management and labor and between industry and Government. Quality and productivity are understood to be the end result of an integrated process which begins with vigorous, committed leadership and ends with a satisfied customer. The essential elements in the revitalization process are organized in this report into seven strategies which represent the major findings of the Second NASA Symposium on Quality and Productivity. Each strategy is then broken down into its principal themes which are presented as recommendations. No one strategy can stand apart from any other; all are interrelated and work together.

Nysmith, C. Robert

A space systems perspective of graphics simulation integration

Creation of an interactive display environment can expose issues in system design and operation not apparent from nongraphics development approaches. Large amounts of information can be presented in a short period of time. Processes can be simulated and observed before committing resources. In addition, changes in the economics of computing have enabled broader graphics usage beyond traditional engineering and design into integrated telerobotics and Artificial Intelligence (AI) applications. The highly integrated nature of space operations often tend to rely upon visually intensive man-machine communication to ensure success. Graphics simulation activities at the Mission Planning and Analysis Division (MPAD) of NASA's Johnson Space Center are focusing on the evaluation of a wide variety of graphical analysis within the context of present and future space operations. Several telerobotics and AI applications studies utilizing graphical simulation are described. The presentation includes portions of videotape illustrating technology developments involving: (1) coordinated manned maneuvering unit and remote manipulator system operations, (2) a helmet mounted display system, and (3) an automated rendezous application utilizing expert system and voice input/output technology.

Brown, R.

Data for The Value of Reversible Carbon Storage in a Zero-Emissions World

Atmospheric carbon dioxide removal (CDR) is required to stabilize global temperature. CDR can be achieved via ecosystem-based approaches that are cost-effective but reversible (e.g., soil and forest management) or by more durable but expensive approaches (e.g., direct air capture coupled with geologic storage). Here, we examine trade-offs between these approaches, focusing on timing, climate impacts, and cost. We simulated reversible carbon accrual for a range of CDR contract structures using a general minimalist model of ecosystem carbon cycling, and parameterized it to simulate US agricultural soil management─specifically cover cropping─as a case study. We then quantified the resulting impact on atmospheric carbon and global temperature using a climate model emulator. We find that maintaining a patchwork of reversible CDR projects by replacing lapsed projects with new projects can reduce warming by 22–195 μ°C in 2100 and that the magnitude of this cooling effect depends on how effectively the patchwork is maintained. Long-term maintenance of reversible CDR projects requires institutional stability that cannot be guaranteed over multiple decades. Consequently, effective CDR ultimately requires replacing reversible projects with durable projects. To address this problem, we modeled the cost of replacing reversible agricultural soil CDR with geologic CDR. We found that using reversible CDR as a bridge to durable CDR is potentially more cost-effective as a global cooling strategy (0.20–0.81 billion USD per μ°C avoided) than perpetual maintenance of reversible CDR (0.32–1.31 billion USD per μ°C avoided) or an immediate transition to durable CDR (1.37–2.19 billion USD per μ°C avoided). However, we emphasize that institutional commitments to maintain reversible CDR projects cannot be guaranteed. Reliance on reversible CDR as a bridge to durable CDR therefore carries an unknown amount of risk and will only function if efforts to maintain reversible CDR are robust.

Carbon

Techno-Economic Analysis of Photovoltaics and Battery Storage for Maine [Slides]

Maine GEO was interested in a small-scale pilot using REopt to expand on previous resilience efforts and better understand the most useful information to gather from facilities to maximize the efficacy of the analysis. The pilot began with identification of three pilot facilities from the existing Maine Community Resilience Partnership (MCRP) cohort, selection of the facilities prioritizing: social vulnerability, community led planning work and commitment to ongoing work. The technical assistance focused on working with identified facilities to help scope the project and identify their goals and then provide technical specifications on optimal energy generation and storage strategies for each community. At the conclusion of the project, participating facilities received a REopt analysis report, including optimal generation and storage strategies to address identified goals and next steps and considerations for implementation.

24 POWER TRANSMISSION AND DISTRIBUTION

An Analysis of Peak Wind Speed Data from Collocated Mechanical and Ultrasonic Anemometers

This study focuses on a comparison of peak wind speeds reported by mechanical and ultrasonic anemometers at Cape Canaveral Air Force Station and Kennedy Space Center (CCAFS/KSC) on the east central coast of Florida and Vandenberg Air Force Base (VAFB) on the central coast of California. The legacy mechanical wind instruments on CCAFS/KSC and VAFB weather towers are being changed from propeller-and-vane (CCAFS/KSC) and cup-and-vane (VAFB) sensors to ultrasonic sensors under the Range Standardization and Automation (RSA) program. The wind tower networks on KSC/CCAFS and VAFB have 41 and 27 towers, respectively. Launch Weather Officers, forecasters, and Range Safety analysts at both locations need to understand the performance of the new wind sensors for a myriad of reasons that include weather warnings, watches, advisories, special ground processing operations, launch pad exposure forecasts, user Launch Commit Criteria (LCC) forecasts and evaluations, and toxic dispersion support. The Legacy sensors measure wind speed and direction mechanically. The ultrasonic RSA sensors have no moving parts. Ultrasonic sensors were originally developed to measure very light winds (Lewis and Dover 2004). The technology has evolved and now ultrasonic sensors provide reliable wind data over a broad range of wind speeds. However, because ultrasonic sensors respond more quickly than mechanical sensors to rapid fluctuations in speed, characteristic of gusty wind conditions, comparisons of data from the two sensor types have shown differences in the statistics of peak wind speeds (Lewis and Dover 2004). The 45th Weather Squadron (45 WS) and the 30 WS requested the Applied Meteorology Unit (AMU) to compare data from RSA and Legacy sensors to determine if there are significant differences in peak wind speed information from the two systems.

Short, David A.

The Space Exploration Initiative: a challenge to advanced life support technologies: keynote presentation

President Bush has enunciated an unparalleled, open-ended commitment to human exploration of space called the Space Exploration Initiative (SEI). At the heart of the SEI is permanent human presence beyond Earth orbit, which implies a new emphasis on life science research and life support system technology. Proposed bioregenerative systems for planetary surface bases will require carefully designed waste processing elements whose development will lead to streamlined and efficient and efficient systems for applications on Earth.

Ecological Systems, Closed

Leading the Public Face of Space

The National Aeronautics and Space Administration (NASA) is fully committed to sharing the excitement of America's international space missions with its stakeholders, particularly the general public. In 2009, the Space Shuttle delivered astronauts to the Hubble Space Telescope to service that great observatory and to the International Space Station to install the observation platform on the Japanese Kibo laboratory. The Lunar Reconnaissance Orbiter is showing an unprecedented view of the Moon, confirming the presence of hardware left behind during the Apollo missions decades ago and helping scientists better understand Earth's natural satellite. These and numerous other exciting missions are fertile subjects for public education and outreach. NASA's core mission includes engaging the public face of space in many forms and forums. Agency goals include communicating with people across the United States and through international opportunities. NASA has created a culture where communication opportunities are valued avenues to deliver information about scientific findings and exploration possibilities. As this presentation will show, NASA's leaders act as ambassadors in the public arena and set expectations for involvement across their organizations. This presentation will focus on the qualities that NASA leaders cultivate to achieve challenging missions, to expand horizons and question "why". Leaders act with integrity and recognize the power of the team multiplier effect on delivering technical performance within budget and schedule, as well as through participation in education and outreach opportunities. Leaders are responsible for budgeting the resources needed to reach target audiences with compelling, relevant information and serve as role models, delivering key messages to various audiences. Examples that will be featured in this presentation include the Student Launch Projects and Great Moonbuggy race, which reach hundreds of students who are a promising pipeline for new scientists and engineers for a new generation of discovery. The popular Exploration Experience trailer is an interactive-exhibit environment that travels across the United States, conveying the innovation necessary for space travel and the wonder of discovery that comes from viewing our planet as part of the larger space-scape.

Dumbacher, Daniel L.

Leading the Public Face of Space

The National Aeronautics and Space Administration (NASA) is fully committed to sharing the excitement of America's international space missions with its stakeholders, particularly the general public. In 2009, the Space Shuttle delivered astronauts to the Hubble Space Telescope to service that great observatory and to the International Space Station to install the observation platform on the Japanese Kibo laboratory. The Lunar Reconnaissance Orbiter is showing an unprecedented view of the Moon, confirming the presence of hardware left behind during the Apollo missions decades ago and helping scientists better understand Earth's natural satellite. These and numerous other exciting missions are fertile subjects for public education and outreach. NASA's core mission includes engaging the public face of space in many forms and forums. Agency goals include communicating with people across the United States and through international opportunities. NASA has created a culture where communication opportunities are valued avenues to deliver information about scientific findings and exploration possibilities. As this presentation will show, NASA's leaders act as ambassadors in the public arena and set expectations for involvement across their organizations. This presentation will focus on the qualities that NASA leaders cultivate to achieve challenging missions, to expand horizons and question "why". Leaders act with integrity and recognize the power of the team multiplier effect on delivering technical performance within budget and schedule, as well as through participation in education and outreach opportunities. Leaders are responsible for budgeting the resources needed to reach target audiences with compelling, relevant information and serve as role models, delivering key messages to various audiences. Examples that will be featured in this presentation include the Student Launch Projects and Great Moonbuggy race, which reach hundreds of students who are a promising pipeline for new scientists and engineers for a new generation of discovery. The popular Exploration Experience trailer is an interactive-exhibit environment that travels across the United States, conveying the innovation necessary for space travel and the wonder of discovery that comes from viewing our planet as part of the larger space-scape.

Dumbacher, Daniel L.

Near-Optimal Performance of Stochastic Model Predictive Control

Here, this article presents a regret analysis for stochastic model predictive control (SMPC) in linear systems with quadratic performance index and additive and multiplicative uncertainties. Under a finite support assumption, the problem can be cast as a finite-dimensional quadratic program, but the problem becomes quickly intractable as the problem size grows exponentially in the horizon length. SMPC aims to compute approximate solutions by solving a sequence of problems with truncated prediction horizons and committing the solution in a receding-horizon fashion. Although this approach is widely used in practice, its performance relative to the optimal solution is not well understood. This article reports for the first time a rigorous near-optimal performance guarantee of SMPC: under stabilizability and detectability conditions, the regret of SMPC is exponentially small in the prediction horizon length, allowing SMPC to achieve near-optimal performance at a substantially reduced computational expense.

93E20, 93B45

Comparison of the KSC-ER Cloud-to-Ground Lightning Surveillance System (CGLSS) and the U.S. National Lightning Detection Network (NLDN)

The NASA Kennedy Space Center (KSC) and Air Force Eastern Range (ER) are located in a region of Florida that experiences the highest area density of lightning strikes to ground in the United States, with values approaching 16 fl/km 2/yr when accumulated in 10x10 km (100 sq km) grids (see Figure 1). Consequently, the KSC-ER use data derived from two cloud-to-ground (CG) lightning detection networks to detect hazardous weather, the "Cloud-to-Ground Lightning Surveillance System" (CGLSS) that is owned and operated by the Air Force and the U.S. National Lightning Detection Network (NLDN) that is owned and operated by Vaisala, Inc. These systems are used to provide lightning warnings for ground operations and to insure mission safety during space launches at the KSC-ER. In order to protect the rocket and shuttle fleets, NASA and the Air Force follow a set of lightning safety guidelines that are called the Lightning Launch Commit Criteria (LLCC). These rules are designed to insure that vehicles are not exposed to the hazards of natural or triggered lightning that would in any way jeopardize a mission or cause harm to the shuttle astronauts. Also, if any CG lightning strikes too close to a vehicle on a launch pad, it can cause time-consuming mission delays due to the extensive retests that are often required for vehicles and/or payloads when this occurs. If any CG lightning strike is missed or mis-located by even a small amount, the result could have significant safety implications, require expensive retests, or create unnecessary delays or scrubs in launches. Therefore, it is important to understand the performance of each lightning detection system in considerable detail.

Ward, Jennifer G.

Emergent constraints on future methane emissions from global wetlands

Future methane (CH 4 ) emissions from natural wetlands are predicted to increase due to global warming, leading to positive feedback on climate change. However, the magnitude of this increase remains highly uncertain. Here we present novel ensemble simulations of seven state-of-the-art terrestrial biosphere models to estimate wetland CH 4 emissions (eCH 4 ) during the twenty-first century. Our estimates suggest that for every 1 °C increase in global land surface temperature, there is a 24 ± 10 Tg CH 4 yr −1 increase in eCH 4 . We also identify an emergent relationship between contemporary temperature dependence and projected eCH 4 . When constrained by 163 site-year eddy-covariance measurements of eCH 4 , we show that wetland emissions can increase by 50–60% by the 2090s relative to the 2010s under a high-warming scenario. The projected decadal increase in eCH 4 from the 2010–2019 baseline to the 2030s would very likely (90% probability) offset an amount equivalent in scale to 8–10% of anthropogenic eCH 4 at the 2020 level, comparable to the reductions committed under the Global Methane Pledge. However, the constraint is dominated by mid- and high-latitude observations, with limited tropical coverage, and uncertainties in projected wetland inundation contribute substantially to uncertainty in eCH 4 . Our findings reduce the uncertainty in projected wetland methane–climate feedback and highlight its potential impacts on methane mitigation efforts to slow global warming.

Zhang, Zhen [Chinese Academy of Sciences (CAS), Be

Staying Current: A Community Readiness Framework for Marine Energy Applied to River Current Energy in Alaska

Marine energy-including wave, tidal, and river current energy-can provide a local energy source for rural and remote communities. Marine energy has the potential to bolster self-sufficiency and create economic opportunities while preserving ecological integrity. Communities may be interested in deploying, testing, and advancing these early-stage technologies to meet their needs. However, limited capacity, workforce constraints, and other barriers can challenge development. To better understand a community's interest in and preparedness for marine energy, we developed a suite of 150 'metrics of readiness.' Organized across seven categories-technical, social, environmental, strategic, governance, economic, financial-and 29 subcategories, the metrics provide a holistic perspective beyond the technical aspects of an energy device. We conducted a desktop application of the metrics of readiness for Igiugig, Alaska. The metrics were applied retrospectively for two points in time: before (2009) and after (2018) in-stream testing of a river current energy device. By documenting changes among categories and subcategories of the metrics, our results show the evolving nature of community readiness for river current energy. They also illustrate how our interdisciplinary framework captures the investment in environmental effects research and commitment to strategic planning that occurred in Igiugig. In future applications, we envision the framework could be used to foster public engagement in marine energy, collaborate with communities in project development, shape capacity building activities, prioritize investments, and inform research needs. While our study focuses on enabling river current energy in Alaska, the metrics of readiness have the potential to inform implementation of other renewable technologies with communities in new geographies.

13 HYDRO ENERGY

ICARTT File Format Enhancements: Supporting FAIRness and Data Discovery of Suborbital Campaign Data

Suborbital campaigns aim to accomplish a wide variety of goals and can include a variety of platforms, instruments, and parameters measured. In 2004, the ICARTT (International Consortium for Atmospheric Research on Transport and Transformation) standards were developed to fulfill data management needs for the ICARTT campaign. The ICARTT file format is text-based and composed of a header with important data description information and the data section. Built on the NASA Ames and GTE data formats, the ICARTT format was created to facilitate data exchange and promote collaborations among the science teams for achieving the ICARTT campaign goals. Due to its success and adaptation for use in many other field campaigns, the ICARTT file format became a NASA standard in 2010 and was amended in January 2017. These changes provided many enhancements, including the requirement for variable standard names. Primarily designed for airborne field studies, ICARTT has been further utilized for ground-based studies. NASA has made a commitment to build an inclusive open science community over the next decade. Open-source science strives to make publicly funded scientific research transparent, inclusive, accessible, and reproducible. The ICARTT format can host metadata that is critical for proper use of the data, particularly for in-situ measurements, and can enhance data discovery and accessibility. However, the required fields are often free text, meaning that the information is human readable, but not machine interpretable. Furthermore, the amount and type of information provided can vary significantly between principal investigators and campaigns. To support FAIR principles and interoperability, enhancements to the ICARTT standards are recommended. Possible recommendations include potential use of controlled and consistent vocabulary for variable standard name and certain common metadata elements; standardizing timestamps for easier data comparisons and analysis; and providing guidance on variable measurement units and how they are reported. Enhancing ICARTT metadata can further streamline the process to make suborbital data more readily available to the data user and improve variable-level metadata. Providing more variable-level metadata can enhance data searching and discovery, supporting NASA’s Open-Source Science Initiative (OSSI).

Megan Buzanowicz

Statistical Uncertainty of Inhalation Dose Coefficients: Impact of Particle Deposition in ICRP 66 Human Respiratory Tract Model

Inhaled radioactive materials can pose a long-term health concern, as the material can be incorporated into the body’s metabolic pathways and remain in organs and tissues for extended durations. During the retention period, the radioactive material may localize in a source organ and irradiate adjacent target organs and tissues. Distribution of these materials changes over time, requiring biokinetic modeling to evaluate their movement through various tissues and organs. The evolving distribution depends on multiple inputs characterizing the inhaled material, such as particle size and size distribution, particle density, aspect ratio, specific radionuclide, the chemical form, and solubility. In addition, biological parameters such as breathing rate, breathing type (nasal or nasal/oral), respiratory system morphometry, tidal volume, functional residual capacity, and anatomical dead space all influence material transport. These aerosol properties and physiological characteristics of the respiratory tract jointly define a range of initial conditions that influence the time-dependent distribution of radioactive material. To evaluate both uncertainty in the initial conditions of inhalation exposure and the final output (committed effective dose) from biokinetic models, a Python-based software tool, Radiological Exposure Dose Calculator (REDCAL), was developed to propagate uncertainty within the human respiratory tract model. Focusing on deposition fraction uncertainty, the primary objective was to characterize the initial activity distribution across respiratory regions as a function of anticipated particle sizes and distributions. The impact of the deposition fraction uncertainty was propagated to committed effective dose coefficients for selected radionuclides in a companion publication. For each particle size, a lognormal distribution, characterized by its geometric mean as defined within ICRP Publication 66, serves as the basis for introducing uncertainty into the physical processes governing deposition in various lung regions. Finally, this study addresses the deposition process and examines how uncertainty in deposition mechanisms affects activity distribution in the airways, ultimately presenting the expected range and standard deviation of deposited activity as a function of particle size.

International Commission on Radiological Protectio

2024 Annual Site Environmental Report for Sandia National Laboratories, Livermore, California

Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly-owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration. The National Nuclear Security Administration’s Sandia Field Office administers the Prime Contract and oversees contractor operations at Sandia National Laboratories, California. Activities at this multi-program engineering and science laboratory support the nuclear weapons stockpile program, energy and environmental research, homeland security, micro- and nanotechnologies, and basic science and engineering research. The U.S. Department of Energy’s National Nuclear Security Administration and its management and operating contractor are committed to fulfilling regulatory obligations, safeguarding the environment, assessing sustainability practices, and ensuring the validity and accuracy of the monitoring data presented in this annual site environmental report (ASER). This report provides a summary of environmental monitoring and compliance activities that occurred at Sandia National Laboratories, California, during calendar year 2024, unless noted otherwise. General site and environmental program information is also included. This report was prepared in accordance with DOE Order 231.1B, Admin Change 1, Environment, Safety and Health Reporting.

54 ENVIRONMENTAL SCIENCES

Flight Motor Set 360T010 (STS-31R). Volume 1: System Overview

Flight motor set 360T010 was launched at approximately 7:34 a.m. CST (090:114:12:33:50.990 GMT) on 24 Apr. 1990 after one launch attempt (attempt on 10 Apr. 1990 was scrubbed following an indication of erratic operation of the Orbiter No. 1 Auciliary Power Unit No. 1). There were no problems with the solid rocket motor launches, overall motor performance was excellent. There were no debris concerns from either motor. Nearly all ballistic contract end item specification parameters were verified with the exception of ignition interval, pressure rise rate, and ignition time thrust imbalance. These could not be verified due to elimination of developmental flight instrumentation on 360L004 (STS-30R) and subsequent, but low sample rate data that were available showed nominal propulsion performance. All ballistic and mass property parameters that could be assessed closely matched the predicted values and were well within the required contract end item specification levels. All field joint heaters and igniter joint heaters performed without anomalies. Evaluation of the ground environment instrumentation measurements again verified thermal model analysis data and showed agreement with predicted environmental effects. No launch commit criteria violations occurred. Postflight inspection again verified nominal performance of the insulation, phenolics, metal parts, and seals. Postflight evaluation indicated both nozzles performed as expected during flight. All combustion gas was contained by insulation in the field and case-to-nozzle joints.

Garecht, Diane

Taming Liquid Hydrogen: The Centaur Upper Stage Rocket, 1958-2002

During its maiden voyage in May 1962, a Centaur upper stage rocket, mated to an Atlas booster, exploded 54 seconds after launch, engulfing the rocket in a huge fireball. Investigation revealed that Centaur's light, stainless-steel tank had split open, spilling its liquid-hydrogen fuel down its sides, where the flame of the rocket exhaust immediately ignited it. Coming less than a year after President Kennedy had made landing human beings on the Moon a national priority, the loss of Centaur was regarded as a serious setback for the National Aeronautics and Space Administration (NASA). During the failure investigation, Homer Newell, Director of Space Sciences, ruefully declared: "Taming liquid hydrogen to the point where expensive operational space missions can be committed to it has turned out to be more difficult than anyone supposed at the outset." After this failure, Centaur critics, led by Wernher von Braun, mounted a campaign to cancel the program. In addition to the unknowns associated with liquid hydrogen, he objected to the unusual design of Centaur. Like the Atlas rocket, Centaur depended on pressure to keep its paper-thin, stainless-steel shell from collapsing. It was literally inflated with its propellants like a football or balloon and needed no internal structure to give it added strength and stability. The so-called "pressure-stabilized structure" of Centaur, coupled with the light weight of its high- energy cryogenic propellants, made Centaur lighter and more powerful than upper stages that used conventional fuel. But, the critics argued, it would never become the reliable rocket that the United States needed.

Dawson, Virginia P.