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At least 235 records · Page 13

UMLS users and uses: a current overview

Abstract The US National Library of Medicine regularly collects summary data on direct use of Unified Medical Language System (UMLS) resources. The summary data sources include UMLS user registration data, required annual reports submitted by registered users, and statistics on downloads and application programming interface calls. In 2019, the National Library of Medicine analyzed the summary data on 2018 UMLS use. The library also conducted a scoping review of the literature to provide additional intelligence about the research uses of UMLS as input to a planned 2020 review of UMLS production methods and priorities. 5043 direct users of UMLS data and tools downloaded 4402 copies of the UMLS resources and issued 66 130 951 UMLS application programming interface requests in 2018. The annual reports and the scoping review results agree that the primary UMLS uses are to process and interpret text and facilitate mapping or linking between terminologies. These uses align with the original stated purpose of the UMLS.

Amos, Liz↗

Three Years of Atmospheric Characterization at Ka/Q-band with the NASA/POLIMI Alphasat Receiver in Milan, Italy

Since June of 2014, NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have jointly conducted a propagation campaign within the framework of the Alphasat propagation experiment through a propagation terminal at the POLIMI campus in Milan, Italy. The terminal utilizes the 20 GHz and 40 GHz beacons broadcast by the Aldo Paraboni Technology Demonstration Payload (TDP #5), and consists of dual coherent Ka- and Q-band beacon receivers. These provide a direct measurement of the signal attenuation and scintillation and are complemented by concurrent weather instrumentation that provides measurements of the atmospheric conditions at the receiver. The primary goal of these measurements is to improve model predictions of communication system performance at 40 GHz. Over three years of concurrent measurements have now been collected from the terminal, and herein we present a statistical analysis of the results thus far, as well as a summary of recent hardware upgrades to the receivers that were made in September 2017.

Radio Transmission↗

Three Years of Atmospheric Characterization at Ka/Q-band with the NASA/POLIMI Alphasat Receiver in Milan, Italy

Since June of 2014, NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have jointly conducted a propagation campaign within the framework of the Alphasat propagation experiment through a propagation terminal at the POLIMI campus in Milan, Italy. The terminal utilizes the 20 GHz and 40 GHz beacons broadcast by the Aldo Paraboni Technology Demonstration Payload (TDP #5), and consists of dual coherent Ka- and Q-band beacon receivers. These provide a direct measurement of the signal attenuation and scintillation and are complemented by concurrent weather instrumentation that provides measurements of the atmospheric conditions at the receiver. The primary goal of these measurements is to improve model predictions of communication system performance at 40 GHz. Over three years of concurrent measurements have now been collected from the terminal, and herein we present a statistical analysis of the results thus far, as well as a summary of recent hardware upgrades to the receivers that were made in September 2017.

Radio Transmission↗

Probabilistic Hazard Assessment for Tornadoes, Straight-Line Wind, and Extreme Precipitation at the Savannah River Site

Recent data sets for three meteorological phenomena with the potential to inflict damage on SRS facilities – tornadoes, straight-line winds, and heavy precipitation – are analyzed using appropriate statistical techniques to estimate the occurrence probabilities for these events in the future. Summaries of the results for DOE-mandated return periods and comparisons to similar calculations performed in 2013 by Werth et al. (W2013) are given. Using tornado statistics for i) the combined states of Georgia and South Carolina, and ii) a 2⁰ square area surrounding SRS, we calculated the probability per year of any location at SRS being struck by a tornado (the ‘strike’ probability) and the probability that any point will experience winds above set thresholds. The strike probability was calculated to be 7.04E-4 (1 chance in 1420) per year and tornadic wind speeds for DOE mandated return periods of 50,000 years (corresponding to wind design category 3 (WDC-3), and 125,000 years (meeting WDC-4) (USDOE, 2016) were estimated to be 132 mph and 147 mph, respectively. By contrast, default tornado wind speeds taken from ANSI/ANS-2.3-2011 are somewhat higher: 161 mph for return periods of 50,000 years and 173 mph every 125,000 years (ANS, 2011). Although the ANS and the SRS evaluation used the same basic model (Ramsdell and Rishel, 2007), the region defined in ANS 2.3 that encompasses the SRS also includes areas of the Great Plains and lower Midwest, regions with much higher occurrence frequencies of strong tornadoes. The SRS straight-line wind values associated with various return periods were calculated by fitting existing wind data to a GEV1 distribution and extrapolating the values for any return period from the tail of that function. For the DOE mandated return periods, we expect straight-line winds of 117 mph every 2500 years (the required WDC-3 standard) and 125 mph every 6250 years (WDC-4) at any point within the SRS. These values are similar to those from the ANS-2.3-2011 report, which has wind speeds of 125mph and 133 mph for return periods of 2500 years and 6250 years, respectively. For extreme precipitation, we compared the fits of two different theoretical extreme-value distributions and applied the one that fit the data best for each of several accumulation periods. The DOE mandated 6-hr accumulated rainfall for return periods of 10,000 years (corresponding to precipitation design category 3 (PDC-3) and 25,000 years (PDC-4) were estimated as 9.1 inches and 10.1 inches, respectively. For the 24-hr rainfall return periods of 10,000 years and 25,000 years, total rainfall estimates were 12.02 inches and 13.17 inches, respectively, higher than comparable values provided in the W2013 report.

54 ENVIRONMENTAL SCIENCES↗

Detectability of Varied Hybridization Scenarios Using Genome-Scale Hybrid Detection Methods

Hybridization events complicate the accurate reconstruction of phylogenies, as they lead to patterns of genetic heritability that are unexpected under traditional, bifurcating models of species trees. This phenomenon has led to the development of methods to infer these varied hybridization events, both methods that reconstruct networks directly, as well as summary methods that predict individual hybridization events from a subset of taxa. However, a lack of empirical comparisons between methods – especially those pertaining to large networks with varied hybridization scenarios – hinders their practical use. Here, we provide a comprehensive review of popular summary methods: TICR, MSCquartets, HyDe, Patterson’s D-Statistic (ABBA-BABA), D3, and Dp. TICR and MSCquartets are based on quartet concordance factors gathered from gene tree topologies and HyDe, Patterson’s D-Statistic, D3, and Dp use site pattern frequencies to identify hybridization events between sets of three taxa. We then use simulated data to address questions of method accuracy and ideal use scenarios by testing methods against complex networks which depict gene flow events that differ in depth (timing), quantity (single vs. multiple, overlapping hybridizations), and rate of gene flow (γ). We find that deeper or multiple hybridization events may introduce noise and weaken the signal of hybridization, leading to higher relative false negative rates across all methods. Despite some forms of hybridization eluding quartet-based detection methods, MSCquartets displays high precision in most scenarios. While HyDe results in high false negative rates when tested on hybridizations involving extinct or unsampled ghost lineages, HyDe is the only method able to identify the direction of hybridization, distinguishing the source parental lineages from recipient hybrid lineages. Lastly, we test the methods on a dataset of ultraconserved elements from the bee subfamily Nomiinae, finding possible hybridization events between clades which correspond to regions of poor support in the species tree estimated in a previous study.

Bjorner, Marianne B.↗

Dataset_for_Conserved_macromolecular_architecture_of_Poplar_secondary_cell_walls_revealed_by_ssNMR_and_atomistic_modeling

This dataset contains solid-state 13C NMR data and atomistic molecular dynamics simulation files supporting the study of nanoscale secondary cell wall architecture across 13 genetically diverse Populus trichocarpa genotypes grown under uniform greenhouse conditions in 13C-enriched CO2 atmospheres (~89% 13C enrichment).The dataset contains two collections of solid-state 13C NMR data. (1) 200 MHz data (Bruker Avance III HD, 4 mm HX probe, 10 kHz MAS): raw Bruker TopSpin experiment folders and DMFIT-exported ascii spectra for selective and non-selective 1D 13C-13C spin diffusion experiments (3000 ms mixing) used to quantify inter-polymer spatial proximities, and short-mixing (1 ms) reference spectra used for polymeric abundance quantification by spectral deconvolution. (2) 600 MHz data (Bruker Avance III, 1.6 mm PhoenixNMR HXY probe, 30 kHz MAS): raw Bruker TopSpin experiment folders containing 2D CORD, 2D CP-INADEQUATE, and 13C/1H relaxation (T1, T1rho) experiments for all 13 genotypes, with processed Excel workbooks per experiment type. Molecular dynamics simulation code, coordinate files, and analysis scripts (NAMD/CHARMM/Python) for six atomistic cell wall models are included. Summarized ssNMR data are compiled into a single excel file and subjected to statistical analysis. Multivariate analysis code (PCA, Pearson correlation) and summary data are provided as excel worksheets and Jupyter notebooks (Python 3).

09 BIOMASS FUELS↗

The 1981 Argentina ground data collection

Over 600 fields in the corn, soybean and wheat growing regions of the Argentine pampa were categorized by crop or cover type and ancillary data including crop calendars, historical crop production statistics and certain cropping practices were also gathered. A summary of the field work undertaken is included along with a country overview, a chronology of field trip planning and field work events, and the field work inventory of selected sample segments. LANDSAT images were annotated and used as the field work base and several hundred ground and aerial photographs were taken. These items along with segment descriptions are presented. Meetings were held with officials of the State Secretariat of Agriculture (SEAG) and the National Commission on Space Investigations (CNIE), and their support to the program are described.

Horvath, R.↗

BATSE software for the analysis of the gamma ray burst spatial distribution

The Burst and Transient Source Experiment (BATSE) on the Gamma Ray Observatory (GRO) is designed to study astronomical gamma ray sources and to provide better positional, spectral, and time resolution about these objects than has previously been possible from one experiment. The procedure to be used in the analysis of the gamma ray burst spatial distribution is presented. Data is input from BATSE via the Gamma Ray Burst Catalog (listing individual burst positions, flux values, and associated errors) and the Sky Sensitivity Map (which summarizes observational selection effects in table format). A FORTRAN program generates Monte Carlo burst catalogs, which are models to be compared to the actual distribution. The Monte Carlo models are then filtered through the Sky Sensitivity Map so that they suffer from the same selection effects as the actual catalog data. Additionally, each burst position is converted into a probability distribution to mimic BATSE positional sensitivity. The Burst Catalog, Monte Carlo burst catalog, and Sky Sensitivity Map are then passed onto an IDL program that compares the catalogs for statistical significance. The Sky Sensitivity Map is used to estimate how often each sky area is observed above the minimum flux level in question. Each burst found in this sky area is then weighted according to the frequency with which this sky area is observed. The catalogs are then compared via tests of homogeneity (based on their radial distributions) and isotropy (based upon their angular distributions). The results of the statistical comparisons along with graphs and charts of the summaries, are output from the IDL program for study.

Hakkila, Jon↗

Gamma-Ray Bursts

Gamma-ray bursts originate from cosmological distances and represent the largest known explosions in the Universe. The observed temporal and spectral characteristics of bursts in the gamma-ray region, primarily from data obtained with the BATSE experiment on the Compton Observatory, will be described. The talk will concentrate on recent studies of burst properties, correlations of GRB parameters and other statistical studies that have recently come to light. A summary of recent discoveries and observations in other wavelength regions will also be presented, along with their implications for models of the burst emission mechanism. Various models for the energy source of gamma-ray bursts will be described.

Fishman, Gearld J.↗

Statistical relation between monthly mean precipitable water and surface-level humidity over global oceans

Monthly summaries of atmospheric soundings taken over 17 years from 49 midocean stations at small islands and weather ships distributed over major oceans are examined. Over tropical oceans, precipitable water is found to be a better predictor of surface-level humidity than surface-level air temperature. A statistical relation in the form of a polynomial is derived; from this relation, the monthly-mean, surface-level mixing ratio can be computed from monthly-mean precipitable water. The root-mean-square differences between the measured and derived values were found to be less than 8 x 10 to the -4th over most ocean areas. Such a relation is useful in deriving large-scale evaporation and latent heat flux data from the ocean, using spaceborne observations. The temporal and spatial variabilities of data deviations from this relation are examined. This relation is found to be applicable to all major ocean basins and can be used to monitor interannual variability. Boundary-layer thermodynamics of different air masses are suggested as an explanation of some characteristics of this relation.

Liu, W. T.↗

Stochastic Analysis for Long Term Capital Structures, Systems, and Components Refurbishment and Replacement

As commercial Nuclear Power Plants (NPPs) pursue extended plant operation in the form of Second License Renewal (SLR), opportunities exist for these plants to provide capital investments to ensure long-term safe and economic performance. At the current time, several utilities have announced an intention to pursue extended operation for one or more of their NPPs via SLR . The goal of this research is to develop a risk-informed approach to evaluate and prioritize plant capital investments made in preparation for, and during the period of, extended plant operations to support decisions for NPP operations. Since the capital investments are influenced by various factors, such as markets, safety and regulatory, the decision-making process of NPP operations should take into account relevant factors for balancing risks, costs and profits. The traditional method of capital budgeting is based on the priority list of candidate projects using economic measures such as benefit-investment ratio, net present value (NPV) and internal rate of return. In the literatures, the problem of capital budgeting or the variant can be represented by an appropriate knapsack problem. The knapsack approach to capital budgeting takes as input as investment, along with the cost and profit of each project. The objective of capital budgeting is to find the combination of the binary decisions for every investment such that the overall profit is as large as possible. The output is a collection of projects to be carried out, and we refer this selected collection of projects as a project portfolio. One limitation of traditional optimization models for capital budgeting is that they do not account for risk/uncertainty in profit and cost streams associated with individual projects, they do not account for risk in resource availability in future years [1,2,3]. Projects can incur cost over-runs, especially when projects are large, performed infrequently, and when there is risk regarding technical viability, external contractors, and/or suppliers of requisite parts and materials. Occasionally, projects are performed ahead of schedule and with cost savings. Planned budgets for capital improvements can be cut and key personnel may be lost. Or, there may be surprise windfalls in budgets for maintenance activities due to decreased costs for “unplanned” maintenance. In these cases, how should we resolve capital budgeting when we have risk forecasts for costs, profits and budgets? One approach we proposed in this summary is to re-solve the optimization models based on assumed statistical distributions of given parameters. If these distributions were not available, a two-stage stochastic optimization approach can be used to provide priority lists to decision-makers to support better risk-informed decisions [4, 5]. In this summary, we will only focus on the first approach.

42 ENGINEERING↗

A2Cloud‐RF : A random forest based statistical framework to guide resource selection for high‐performance scientific computing on the cloud

Summary This article proposes a random‐forest based A2Cloud framework to match scientific applications with Cloud providers and their instances for high performance. The framework leverages four engines for this task: PERF engine, Cloud trace engine, A2Cloud‐ext engine, and the random forest classifier (RFC) engine. The PERF engine profiles the application to obtain performance characteristics, including the number of single‐precision (SP) floating‐point operations (FLOPs), double‐precision (DP) FLOPs, x87 operations, memory accesses, and disk accesses. The Cloud trace engine obtains the corresponding performance characteristics of the selected Cloud instances including: SP floating point operations per second (FLOPS), DP FLOPS, x87 operations per second, memory bandwidth, and disk bandwidth. The A2Cloud‐ext engine uses the application and Cloud instance characteristics to generate objective scores that represent the application‐to‐Cloud match. The RFC engine uses these objective scores to generate two types of random forests to assist users with rapid analysis: application‐specific random forests (ARF) and application‐class based random forests. The ARF consider only the input application's characteristics to generate a random forest and provide numerical ratings to the selected Cloud instances. To generate the application‐class based random forests, the RFC engine downloads the application profiles and scores of previously tested applications that perform similar to the input application. Using these data, the RFC engine creates a random forest for instance recommendation. We exhaustively test this framework using eight real‐world applications across 12 instances from different Cloud providers. Our tests show significant statistical agreement between the instance ratings given by the framework and the ratings obtained via actual Cloud executions.

Samuel, David↗

BioXTAS RAW 2 : new developments for a free open-source program for small-angle scattering data reduction and analysis

BioXTAS RAW is a free open-source program for reduction, analysis and modelling of biological small-angle scattering data. Here, the new developments in RAW version 2 are described. These include improved data reduction using pyFAI ; updated automated Guinier fitting and D max finding algorithms; automated series ( e.g. size-exclusion chromatography coupled small-angle X-ray scattering or SEC-SAXS) buffer- and sample-region finding algorithms; linear and integral baseline correction for series; deconvolution of series data using regularized alternating least squares ( REGALS ); creation of electron-density reconstructions using electron density via solution scattering ( DENSS ); a comparison window showing residuals, ratios and statistical comparisons between profiles; and generation of PDF reports with summary plots and tables for all analysis. Furthermore, there is now a RAW API, which can be used without the graphical user interface (GUI), providing full access to all of the functionality found in the GUI. In addition to these new capabilities, RAW has undergone significant technical updates, such as adding Python 3 compatibility, and has entirely new documentation available both online and in the program.

97 MATHEMATICS AND COMPUTING↗

NEWTS Well Summary by Hydrologic Regions and Subbasins in the U.S.

Oil and gas well production data (2000-2022), including water production and injection, as well as summary information (e.g., well count by status, total vertical depth statistics, etc.) spatially summarized by Watershed Boundary Dataset's (WBD) region (Hydrologic Unit Code (HUC) 2) and subbasin (HUC8). Energy-related produced waters data were acquired and summarized in support of the development of the National Energy Technology Laboratory's NEWTS (National Energy Water Treatment and Speciation Database). Due to the proprietary nature of the wellbore data, this derived product has been spatially compiled by key areas to support research and stakeholder needs.

Energy Infrastructure↗

The Multi-scenario Extreme Weather Simulator: Energy Resilience for Mission Assurance

The Multi-scenario extreme weather simulator (MEWS) is a stochastic weather generation tool. The MEWS algorithm uses 50 or more years of National Oceanic and Atmospheric Association (NOAA) daily summaries [1] for maximum and minimum temperature and NOAA climate norms [2] to calculate historical heat wave and cold snap statistics. The algorithm takes these statistics and shifts them according to multiplication factors provided in the Intergovernmental Panel on Climate Change (IPCC) physical basis technical summary [3] for heat waves.

54 ENVIRONMENTAL SCIENCES↗

Adaptation to transient postural perturbations

This research was first proposed in May, 1986, to focus on some of the problems encountered in the analysis of postural responses gathered from crewmembers. The ultimate driving force behind this line of research was the desire to treat, predict, or explain 'Space Adaptation Syndrome' (SAS) and hence circumvent any adverse effects of space motion sickness on crewmember performance. The aim of this project was to develop an easily implemented analysis of the transient responses to platform translation that can be elicited with a protocol designed to force sensorimotor reorganization, utilizing statistically reliable criterion measures. This report will present: (1) a summary of the activity that took place in each of the three funded years of the project; (2) discussion of experimental results and their implications for future research; and (3) a list of presentations and publications resulting from this project.

Andres, Robert O.↗

Martian Polar Region Impact Craters: Topographical Perspectives from the Mars Orbiter Laser Altimeter

The Mars Orbiter Laser Altimeter (MOLA) has acquired over 100 topographic cross-sections of impact landforms in the polar regions of Mars as part of Mars Global Surveyor (MGS) Science Phasing Orbit observations during the period from April to July, 1998. These MOLA topographic profiles offer the first three-dimensional perspectives of high latitude craters on Mars yet available, and provide evidence of landform geometries not previously recognized. Indeed, the relatively poor quality of Viking Orbiter images of many high northern latitude regions has allowed the MOLA data to provide insights into the cavities and ejecta topologies of non-degraded impact landforms that have clearly experienced interactions with condensates, either as part of their formation, or as a post-modification stage effect. Here we report a preliminary summary of the results associated with topographic measurements for a statistically significant population of impact features all of which lie north of 60N latitude. MOLA sampled four impact features with frost-related interior deposits, including the 81 km (diameter) Korolev feature. In several cases, there is evidence from near-centerline MOLA cross-sections of crater interior features (i.e., central peak or ice-dust deposits) that are anomalously large relative to the crater cavity. Central structures that make up more than 50% of the volume of a crater cavity are observed, suggesting that either substantial accumulation of mantling materials has occurred, or that crater excavation triggered production of volume-enhancing materials (ice?). Pedestal craters sampled by MOLA also attest to enhanced production of ejecta materials in high latitude terrains. For example, many of the pedestal craters suggest a volume of ejecta (Ve) to volume of cavity (Vc) ratio far in excess of 1.0 (i.e., over 3.0), even in cases where the floor of the cavity appears unfilled. Finally, the well-defined transitions between simple and complex craters observed in MOLA data for non-polar latitude impact features is not preserved at high northern latitudes (for non-degraded craters). This further suggests the role of target materials (i.e., frozen volatiles?) in the cratering process on Mars in such regions.

Garvin, J. B.↗

Effect of Temperature on Jet Velocity Spectra

Statistical jet noise prediction codes that accurately predict spectral directivity for both cold and hot jets are highly sought both in industry and academia. Their formulation, whether based upon manipulations of the Navier-Stokes equations or upon heuristic arguments, require substantial experimental observation of jet turbulence statistics. Unfortunately, the statistics of most interest involve the space-time correlation of flow quantities, especially velocity. Until the last 10 years, all turbulence statistics were made with single-point probes, such as hotwires or laser Doppler anemometry. Particle image velocimetry (PIV) brought many new insights with its ability to measure velocity fields over large regions of jets simultaneously; however, it could not measure velocity at rates higher than a few fields per second, making it unsuitable for obtaining temporal spectra and correlations. The development of time-resolved PIV, herein called TR-PIV, has removed this limitation, enabling measurement of velocity fields at high resolution in both space and time. In this paper, ground-breaking results from the application of TR-PIV to single-flow hot jets are used to explore the impact of heat on turbulent statistics of interest to jet noise models. First, a brief summary of validation studies is reported, undertaken to show that the new technique produces the same trusted results as hotwire at cold, low-speed jets. Second, velocity spectra from cold and hot jets are compared to see the effect of heat on the spectra. It is seen that heated jets possess 10 percent more turbulence intensity compared to the unheated jets with the same velocity. The spectral shapes, when normalized using Strouhal scaling, are insensitive to temperature if the stream-wise location is normalized relative to the potential core length. Similarly, second order velocity correlations, of interest in modeling of jet noise sources, are also insensitive to temperature as well.

Bridges, James E.↗