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At least 325 records · Page 18

Do analogs of the Hoyle state exist in {sup 16}O?

The root-mean-square radii of short-lived 0{sup +}-states in {sup 16}O were obtained for the first time from an analysis of α+{sup 16}O diffraction scattering. Data on elastic and inelastic α+{sup 16}O scattering were analyzed on the basis of the modified diffraction model in the range of projectile energies between a few tens of MeV units to 400 MeV. No case of a significant enhancement of the radius with respect to its ground-state value was observed. In particular, this concerns the 15.1-MeV 0{sub 6}{sup +} state, which lies near the threshold for breakup to four alpha particles and for which we did not confirm a giant radius predicted by the alpha-particle-condensate model. This result disproves the hypothesis that the {sup 16}O nucleus in the 0{sub 6}{sup +} state has a rarefied structure and appears to be an analog of the known Hoyle state at 7.65 MeV (0{sub 2}{sup +}) in {sup 12}C.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Radiation-induced chromosomal instability in human mammary epithelial cells

Karyotypes of human cells surviving X- and alpha-irradiation have been studied. Human mammary epithelial cells of the immortal, non-tumorigenic cell line H184B5 F5-1 M/10 were irradiated and surviving clones isolated and expanded in culture. Cytogenetic analysis was performed using dedicated software with an image analyzer. We have found that both high- and low-LET radiation induced chromosomal instability in long-term cultures, but with different characteristics. Complex chromosomal rearrangements were observed after X-rays, while chromosome loss predominated after alpha-particles. Deletions were observed in both cases. In clones derived from cells exposed to alpha-particles, some cells showed extensive chromosome breaking and double minutes. Genomic instability was correlated to delayed reproductive death and neoplastic transformation. These results indicate that chromosomal instability is a radiation-quality-dependent effect which could determine late genetic effects, and should therefore be carefully considered in the evaluation of risk for space missions.

NASA Center JSC↗

Comparative analysis of 11 different radioisotopes for palliative treatment of bone metastases by computational methods

Purpose: Throughout the years, the palliative treatment of bone metastases using bone seeking radiotracers has been part of the therapeutic resources used in oncology, but the choice of which bone seeking agent to use is not consensual across sites and limited data are available comparing the characteristics of each radioisotope. Computational simulation is a simple and practical method to study and to compare a variety of radioisotopes for different medical applications, including the palliative treatment of bone metastases. This study aims to evaluate and compare 11 different radioisotopes currently in use or under research for the palliative treatment of bone metastases using computational methods. Methods: Computational models were used to estimate the percentage of deoxyribonucleic acid (DNA) damage (fast Monte Carlo damage algorithm), the probability of correct DNA repair (Monte Carlo excision repair algorithm), and the radiation-induced cellular effects (virtual cell radiobiology algorithm) post-irradiation with selected particles emitted by phosphorus-32 ({sup 32}P), strontium-89 ({sup 89}Sr), yttrium-90 ({sup 90}Y ), tin-117 ({sup 117m}Sn), samarium-153 ({sup 153}Sm), holmium-166 ({sup 166}Ho), thulium-170 ({sup 170}Tm), lutetium-177 ({sup 177}Lu), rhenium-186 ({sup 186}Re), rhenium-188 ({sup 188}Re), and radium-223 ({sup 223}Ra). Results: {sup 223}Ra alpha particles, {sup 177}Lu beta minus particles, and {sup 170}Tm beta minus particles induced the highest cell death of all investigated particles and radioisotopes. The cell survival fraction measured post-irradiation with beta minus particles emitted by {sup 89}Sr and {sup 153}Sm, two of the most frequently used radionuclides in the palliative treatment of bone metastases in clinical routine practice, was higher than {sup 177}Lu beta minus particles and {sup 223}Ra alpha particles. Conclusions: {sup 223}Ra and {sup 177}Lu hold the highest potential for palliative treatment of bone metastases of all radioisotopes compared in this study. Data reported here may prompt future in vitro and in vivo experiments comparing different radionuclides for palliative treatment of bone metastases, raise the need for the careful rethinking of the current widespread clinical use of {sup 89}Sr and {sup 153}Sm, and perhaps strengthen the use of {sup 223}Ra and {sup 177}Lu in the palliative treatment of bone metastases.

60 APPLIED LIFE SCIENCES↗

On nonthermal processes in the core of the Sun

Nonthermal nuclear processes in the core of the Sun that are induced by fast particles appearing as nonthermalized products of exothermic reactions are discussed. Among other things, properties of 8.7-MeV alpha particles originating from the reaction p + {sup 7}Li → 2α are studied, and their effect on the balance of the processes p + {sup 17}O ai α + {sup 14}N, which close the CNO-II cycle, is determined. It is shown that the effective temperature of fast alpha particles is approximately 1000 times as high as the temperature of the plasma in the Sun’s core and that, under some specific conditions, the rate of the reverse reaction α + {sup 14}N → p + {sup 17}O may be one to two orders of magnitude higher than the rate of the forward reaction p + {sup 17}O → α + {sup 14}N.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

National Ignition Campaign Data Analysis by an ICF Outsider

A simple DT burn model, with no alpha-particle warming feedback, using a combination of ICF inputs and the measured ion temperature, T, volume compression, C, ablator velocity, v, and burn width time, Δt, can reproduce the national-ignition campaign (NIC) fusion yields with a rms percent difference of ~40%. Analysis suggestion the fusion-yield reproducibility of NIC events with nominally identically measured T, C, v, and Δt is <30%. The highest fusion yields, at a fixed laser energy are obtained with depleted-uranium (DU) hohlraums and high-density carbon (HDC) ablators. Small diameter fit tubes (≤5 μm) enhance fusion yields by an average of 26±15% relative to 10-μm diameter fit tubes. A dependence of fusion yield on the diameter of the capsule relative to the diameter of the hohlraum is inferred for fixed T, C, v, and Δt. No evidence of conditions close to ignition, or alpha-particle warming is found in the existing NIC data with LEH< 2MJ. To obtain a predictive model for extrapolation proposes we map the T, C, and v into power laws as a function of LEH. The above mentioned extrapolatable model has a rms percent difference from the yields of the second half of the NIC of (56 ± 4)%. Higher (and significantly lower) DT temperatures are obtained with HDC ablators (and low-foot drives). The highest compressions are obtained via low-foot drives, but this does not compensate for the corresponding lower temperatures. An extrapolation of the presented model suggests significant alpha-particle heating at an LEH of ~5 MJ. It is hoped that others more familiar it the conditions needed for ignition will use to presented model to estimate the LEH required for ignition.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Relative abundance of proton to helium nuclei in solar cosmic ray events

A statistical study of the relative abundance of proton to alpha particles at equal energy per nucleon has been carried out on the basis of some hundred solar particle events in the energy range 6-20 MeV/nuc. A small qualitative effect of the coronal propagation has been found for events associated with solar flares away from the observer 'preferred connection region' (20-80 deg W from the central meridian). The variation of the relative abundance of the proton to alpha particle at ejection is analyzed using events for which the coronal transport is minimum. It is found that micro events characterized by small proton intensity, little or no scattering in interplanetary medium and little or no trapping in the corona has an abundance of He-4 of 5-30% relative to proton. Those events frequently display a very high He-3 abundance from 30 to 150% relatively to He-4. For larger particle events, the alpha abundance decreases following a relation which is not valid for flare-associated events that accelerate particles to relativistic energies.

Van Hollebeke, M. A. I.↗

Coherent fragmentation of {sup 12}C nuclei of momentum 4.5 GeV/c per nucleon through the {sup 8}Be{sub g.s.}+{sup 4}He channel in a nuclear photoemulsion containing lead nuclei

A two-particle channel in which an unbound nucleus of {sup 8}Be in the ground state ({sup 8}Be{sub g.s.}) was one of the fragments was selected among events where {sup 12}C nuclei of momentum 4.5 GeV/c per nucleon undergo coherent dissociation into three alpha particles. The events in question were detected in a track nuclear photoemulsion containing lead nuclei, which was irradiated at the synchrophasotron of the Laboratory of High Energies at the Joint Institute for Nuclear Research (JINR, Dubna). The average transverse momentum of alpha particles produced upon the decay of {sup 8}Be{sub g.s.} nuclei was 87±6 MeV/c, while that for “single” alpha (α{sub s}) particles was 123±15 MeV/c. The average value of the transverse-momentum transfer in the reaction being considered, Pt(12C), was 223 ± 20 MeV/c. The average value of the cross section for this channel involving Ag and Br target nuclei was 13 ± 4 mb, while the cross section for the reaction on the Pb nucleus was 40 ± 15 mb. The Coulomb dissociation contribution evaluated on the basis of the number of events where the momentum P{sub t}({sup 12}C) did not exceed 0.1 GeV/c saturated about 20%. In nine events, the measured total transverse energy of the fragments in the reference frame comoving with the decaying carbon nucleus did not exceed 0.45 MeV, which did not contradict the excitation of the participant {sup 12}C nucleus to the level at 7.65 MeV. The average value of the transverse momentum in those events was 234 ± 25 MeV/c.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Radiation-induced bystander effect and adaptive response in mammalian cells

Two conflicting phenomena, bystander effect and adaptive response, are important in determining the biological responses at low doses of radiation and have the potential to impact the shape of the dose-response relationship. Using the Columbia University charged-particle microbeam and the highly sensitive AL cell mutagenic assay, we show here that non-irradiated cells acquire mutagenesis through direct contact with cells whose nuclei have been traversed with a single alpha particle each. Pretreatment of cells with a low dose of X-rays four hours before alpha particle irradiation significantly decreased this bystander mutagenic response. Results from the present study address some of the fundamental issues regarding both the actual target and radiation dose effect and can contribute to our current understanding in radiation risk assessment. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

NASA Discipline Radiation Health↗

Application of Benchmarked Kinetic Resistive Wall Mode Stability Codes to ITER, Including Additional Physics

Leading resistive wall mode (RWM) stability codes MARS-K [Y. Liu, et al., Phys. Plasmas 15, 112503 (2008)] and MISK [B. Hu, et al., Phys. Plasmas 12, 057301 (2005)] have been previously benchmarked. The benchmarking has now been extended to include additional physics, and used to project the stability of ITER in a realistic operating space. Due to ITER's relatively low plasma rotation and collisionality, collisions and non-resonance rotational effects were both found to have little impact on stability, and these non-resonance rotational effects also will not self-consistently affect the ITER RWM eigenfunction. Resonances between thermal ions and electrons and the expected level of ITER toroidal rotation were found to be important to stability, as were alpha particles, which are not in rotational resonance. MISK calculations show that without alpha particles, ITER is projected to be unstable to the RWM, but the expected level of alphas is calculated to provide a sufficient level of stability.

Resistive Wall Mode Stability↗

Effect of Radiation from Low-Level Radioactive Waste Leachate on Antioxidant Depletion in HDPE Geo-membrane - 16087

Low-level radioactive waste (LLW) and mixed waste (MW) disposal facilities in the US are required to have a service life in excess of 1000 yr. Understanding the rate of degradation of high-density polyethylene (HDPE) geo-membranes (GMs) used in LLW and MW facilities is necessary to assess their service life when conducting a performance assessment for a disposal facility. In LLW and MW disposal facilities, GMs may be exposed to radionuclides that may accelerate antioxidant depletion and degradation. This paper evaluates how radiation dosage affects antioxidant depletion in HDPE GMs and makes inferences regarding the impact of radiation on GM service life. Specimens of 0.04-mm-, 0.1-mm-, and 2-mm-thick HDPE GMs were exposed to a sealed source of Am-241 to simulate alpha radiation from LLW leachate (e.g., uranium). The specimens were exposed to the sealed source for 1-50 h, followed by oxidative induction time (OIT) testing to determine depletion of antioxidants in response to exposure. Penetration of alpha particles in the HDPE GM exposed to the sealed source was evaluated with the program Geometry And Tracking (GEANT4). The GEANT4 modeling indicates that physical dose deposition for alpha particles largely occurs on the superficial layers and decreased monotonically with depth to a negligible dose (∼ 28 μm). For a 2-mm-thick HDPE GM, there was no change in OIT after exposure, whereas in much thinner GMs (e.g., 0.04 mm), significant antioxidant depletion occurred after exposure, reflecting the shallow penetration of alpha radiation at the surface of HDPE GM. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Multi-particle inspection using associated particle sources

Disclosed herein are representative embodiments of methods, apparatus, and systems for performing combined neutron and gamma ray radiography. For example, one exemplary system comprises: a neutron source; a set of alpha particle detectors configured to detect alpha particles associated with neutrons generated by the neutron source; neutron detectors positioned to detect at least some of the neutrons generated by the neutron source; a gamma ray source; a set of verification gamma ray detectors configured to detect verification gamma rays associated with gamma rays generated by the gamma ray source; a set of gamma ray detectors configured to detect gamma rays generated by the gamma ray source; and an interrogation region located between the neutron source, the gamma ray source, the neutron detectors, and the gamma ray detectors.

42 ENGINEERING↗

Monte Carlo mixture model of lifetime cancer incidence risk from radiation exposure on shuttle and international space station

Estimating uncertainty in lifetime cancer risk for human exposure to space radiation is a unique challenge. Conventional risk assessment with low-linear-energy-transfer (LET)-based risk from Japanese atomic bomb survivor studies may be inappropriate for relativistic protons and nuclei in space due to track structure effects. This paper develops a Monte Carlo mixture model (MCMM) for transferring additive, National Institutes of Health multiplicative, and multiplicative excess cancer incidence risks based on Japanese atomic bomb survivor data to determine excess incidence risk for various US astronaut exposure profiles. The MCMM serves as an anchor point for future risk projection methods involving biophysical models of DNA damage from space radiation. Lifetime incidence risks of radiation-induced cancer for the MCMM based on low-LET Japanese data for nonleukemia (all cancers except leukemia) were 2.77 (90% confidence limit, 0.75-11.34) for males exposed to 1 Sv at age 45 and 2.20 (90% confidence limit, 0.59-10.12) for males exposed at age 55. For females, mixture model risks for nonleukemia exposed separately to 1 Sv at ages of 45 and 55 were 2.98 (90% confidence limit, 0.90-11.70) and 2.44 (90% confidence limit, 0.70-10.30), respectively. Risks for high-LET 200 MeV protons (LET=0.45 keV/micrometer), 1 MeV alpha-particles (LET=100 keV/micrometer), and 600 MeV iron particles (LET=180 keV/micrometer) were scored on a per particle basis by determining the particle fluence required for an average of one particle per cell nucleus of area 100 micrometer(2). Lifetime risk per proton was 2.68x10(-2)% (90% confidence limit, 0.79x10(-3)%-0. 514x10(-2)%). For alpha-particles, lifetime risk was 14.2% (90% confidence limit, 2.5%-31.2%). Conversely, lifetime risk per iron particle was 23.7% (90% confidence limit, 4.5%-53.0%). Uncertainty in the DDREF for high-LET particles may be less than that for low-LET radiation because typically there is very little dose-rate dependence. Probability density functions for high-LET radiation quality and dose-rate may be preferable to conventional risk assessment approaches. Nuclear reactions and track structure effects in tissue may not be properly estimated by existing data using in vitro models for estimating RBEs. The method used here is being extended to estimate uncertainty in spacecraft shielding effectiveness in various space radiation environments.

NASA Center LaRC↗

The Apollo Alpha Spectrometer.

Located in the Science Instrument Module of Apollo 15 and 16, the Alpha Particle Spectrometer was designed to detect and measure the energy of alpha particles emitted by the radon isotopes and their daughter products. The spectrometer sensor consisted of an array of totally depleted silicon surface barrier detectors. Biased amplifier and linear gate techniques were utilized to reduce resolution degradation, thereby permitting the use of a single 512 channel PHA. Sensor identification and in-flight radioactive calibration were incorporated to enhance data reduction.

Jagoda, N.↗

Coil optimization for quasi-helically symmetric stellarator configurations

Filament-based coil optimizations are performed for several quasi-helical stellarator configurations, beginning with the one from Landreman & Paul ( Phys. Rev. Lett. , vol. 128, 2022, 035001), demonstrating that precise quasi-helical symmetry can be achieved with realistic coils. Several constraints are placed on the shape and spacing of the coils, such as low curvature and sufficient plasma–coil distance for neutron shielding. The coils resulting from this optimization have a maximum curvature 0.8 times that of the coils of the Helically Symmetric eXperiment (HSX) and a mean squared curvature 0.4 times that of the HSX coils when scaled to the same plasma minor radius. When scaled up to reactor size and magnetic field strength, no fast particle losses were found in the free-boundary configuration when simulating 5000 alpha particles launched at $3.5\,\mathrm {MeV}$ on the flux surface with a normalized toroidal flux of $s=0.5$ . An analysis of the tolerance of the coils to manufacturing errors is performed using a Gaussian process model, and the coils are found to maintain low particle losses for smooth, large-scale errors up to amplitudes of approximately $0.15\,\mathrm {m}$ . Another coil optimization is performed for the Landreman–Paul configuration with the additional constraint that the coils are purely planar. Visual inspection of the Poincaré plot of the resulting magnetic field-lines reveal that the planar modular coils alone do a poor job of reproducing the target equilibrium. Additional non-planar coil optimizations are performed for the quasi-helical configuration with $5\,\%$ volume-averaged plasma beta from Landreman et al. ( Phys. Plasma , vol. 29, issue 8, 2022, 082501), and a similar configuration also optimized to satisfy the Mercier criterion. The finite beta configurations had larger fast-particle losses, with the free-boundary Mercier-optimized configuration performing the worst, losing approximately $5.5\,\%$ of alpha particles launched at $s=0.5$ .

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

In vitro cell irradiation systems based on 210Po alpha source: construction and characterisation

One way of studying the risk to human health of low-level radiation exposure is to make biological experiments on living cell cultures. Two 210Po alpha-particle emitting devices, with 0.5 and 100 MBq activity, were designed and constructed to perform such experiments irradiating monolayers of cells. Estimates of dose rate at the cell surface were obtained from measurements by a PIPS alpha-particle spectrometer and from calculations by the SRIM 2000, Monte Carlo charged particle transport code. Particle fluence area distributions were measured by solid state nuclear track detectors. The design and dosimetric characterisation of the devices are discussed. c2002 Elsevier Science Ltd. All rights reserved.

Alpha Particles↗

Theory of the Lamb Shift and fine structure in muonic {sup 4}He ions and the muonic {sup 3}He– {sup 4}He Isotope Shift

We provide an up to date summary of the theory contributions to the 2S → 2P Lamb shift and the fine structure of the 2P state in the muonic helium ion (μ{sup 4}He){sup +}. This summary serves as the basis for the extraction of the alpha particle charge radius from the muonic helium Lamb shift measurements at the Paul Scherrer Institute, Switzerland. Individual theory contributions needed for a charge radius extraction are compared and compiled into a consistent summary. The influence of the alpha particle charge distribution on the elastic two-photon exchange is studied to take into account possible model-dependencies of the energy levels on the electric form factor of the nucleus. We also discuss the theory uncertainty which enters the extraction of the {sup 3}He–{sup 4}He isotope shift from the muonic measurements. The theory uncertainty of the extraction is much smaller than a present discrepancy between previous isotope shift measurements. This work completes our series of n=2 theory compilations in light muonic atoms which we have performed already for muonic hydrogen, deuterium, and helium-3 ions.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Plasma Energetic Particles Simulation Center (PEPSC)

The main effort of the Texas group was to develop theoretical and simplified numerical models to understand chirping phenomena often seen for Alfven and geodesic acoustic waves in experimental plasmas such as D-III-D, NSTX and JET. Its main numerical effort was to modify the AEGIS code, which was originally developed as an eigenvalue solver. To apply to the chirping problem this code has to be able to treat the linear response to the continuum and the response of the plasma to external drive or to an internal drive that comes from the formation of phase space chirping structures. The theoretical underpinning of this investigation still needed to be more fully developed to understand how to best formulate the theoretical problem. Considerable progress was made on this front by B.N. Breizman and his collaborators and a new reduced model was developed by H. L. Berk and his PhD student, G. Wang which can be uses as simplified model to describe chirping in a large aspect ratio tokamak. This final report will concentrate on these two directions that were developed as well as results that were found in the work with the AEGIS code and in the progress in developing a novel quasi-linear formulation for a description of Alfvenic modes destabilized by energetic particles, such as alpha particles in a burning plasma.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Charged particles in the magnetosphere.

Charged particle population dynamics in outer radiation zone of magnetosphere, discussing ring current particles, protons, electrons, alpha particles and electric field

Van Allen, J. A.↗