Search NASA⌕ Search

SEARCH · Search NASA

Results for “Activity detection”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 505 records · Page 28

Robotic External Leak Locator (RELL) Leak Plume Field Detection on the International Space Station (ISS)

The Robotic External Leak Locator (RELL) was deployed to the International Space Station (ISS) with the objective of demonstrating the ability to detect and locate small leaks. On-orbit operations began in late November 2016 and following scanning activities to characterize the natural and induced environment of the ISS, RELL focused on the United States External Active Thermal Control System (EATCS). RELL successfully detected ammonia related to a known small ammonia leak in the port-side EATCS, with the highest pressure values around the inboard Radiator Beam Valve Module 1 (RBVM 1). An additional day of scanning was subsequently performed in December 2017 to focus on RBVM 1. RELL was approved for additional external operations in February 2017 with the goal of fine tuning the location of the leak. Using grid scanning patterns, RELL detected ammonia around RBVM 1 and located the approximate source of the leak. The potential leak site was inspected by a crew member during an Extravehicular Activity (EVA) in March 2017, and the suspected radiator-side lines were isolated from the port-side EATCS coolant loop in April 2017. Subsequent monitoring of the system pressures showed that the leak has stopped, indicating RELL accurately located the source of the EATCS leak. These activities verify that RELL enhances the ISS Program's ability to not only locate small leaks, but isolate the source with minimal impact to the entire ISS system.

External Active Thermal Control System↗

Radar detection of surface oil accumulations

The United States Coast Guard is developing AIREYE, an all weather, day/night airborne surveillance system, for installation aboard future medium range surveillance aircraft. As part of this program, a series of controlled tests were conducted off southern California to evaluate the oil slick detection capabilities of two Motorola developed, side looking radars. The systems, a real aperture AN/APS-94D and a synthetic aperture coherent on receive (COR) were flown over the Santa Barbara Channel on May 19, 1976. Targets imaged during the coincident overflights included natural oil seepage, simulated oil spills, oil production platforms, piers, mooring buoys, commercial boats and barges at other targets. Based on an analysis of imagery from the coincident radar runs, COR provides better detection of natural and man made oil slicks, whereas the AN/APS-94D consistently exhibited higher surface target detection results. This and other tests have shown that active microwave systems have considerable potential for aiding in the detection and analysis of surface oil accumulations.

Estes, J. E.↗

Detection and Screening of Organic Contaminants in A Riverine System of Georgia Using Non-Targeted Analysis

Numerous organic chemicals exist within aquatic environments, yet effectively screening and prioritizing them is a huge challenge. This study provides a comprehensive investigation into the ecological dynamics of the North Oconee River within Athens-Clarke County, Georgia, with a specific focus on the distribution of 33 identified compounds, including a prominent pesticide. The research, conducted in the riverine ecosystems proximal to the Firefly trail, employs advanced analytical techniques to elucidate potential contamination sources arising from agricultural and urban runoff. Intriguingly, the study reveals North Oconee River near the Firefly Trail as a notable site for heightened pesticide contamination, warranting a meticulous exploration of its origins. Furthermore, the investigation unveils the intricate microbial degradation processes of malathion within the North Oconee River, elucidating the pivotal role played by microbial activity in river water. The detection of degradant byproducts prompts the considerations of bioavailability and toxicity, associating potential implications for the river’s overall ecological health. Ongoing research endeavors to precisely quantify environmental risks and unravel indigenous microbial degradation pathways, presenting pivotal contributions to the scientific community’s understanding of complex riverine ecosystems. This research serves as a foundational piece in informing sustainable environmental management practices and emphasizes the urgency of comprehensive stewardship in safeguarding aquatic ecosystems.

54 ENVIRONMENTAL SCIENCES↗

Exposure to Microgravity for 30 Days Onboard Bion M1 Caused Muscle Atrophy and Decreased Regeneration in the Mouse Femoral Quadriceps

Mechanical unloading of muscle during spaceflight in microgravity is known to cause muscular atrophy, changes in muscle fiber type composition, gene expression, and reductions in regenerative muscle growth. Although limited data exists for long-term effects of microgravity in human muscle, these processes have mostly been studied in rodents for short periods of time. Here we report on how 30-day, long-term, mechanical unloading in microgravity affects mouse muscle of the femoral Quadriceps group. To conduct these studies we used muscle tissue from 6 mice from the NASA Biospecimen Sharing Program conducted in collaboration with the Institute for Biomedical Problems of the Russian Academy of Sciences, during the Russian Bion M1 biosatellite mission in 2013. Muscle morphology observed in histological sections shows signs of extensive atrophy and regenerative hypoplasia. Specifically, we observed a two-fold decrease in the number of myonuclei, their central location, low density of myofibers and myofibrils, in fragmentation and swelling of myofibers. Despite obvious atrophy, muscle regeneration nevertheless appears to have continued after 30 days in microgravity as evidenced by thin and short newly formed myofibers. Many of them however showed evidence of apoptotic, TUNEL positive cells and myofibrils degradation, suggesting long-term unloading in microgravity affects late stages of myofiber differentiation. Ground asynchronous and vivarium control animals showed normal, well-developed tissue structure with sufficient blood and nerve supply and evidence of regenerative formation of new myofibers free of apoptotic nuclei. Myonuclei stress response in spaceflight animals was detected by positive nuclear immunolocalization of c-jun and c-myc proteins. Regenerative activity of satellite cells in muscles is detected in mice of all animal groups, by pax7, MyoD, and myogenin immunostaining and myogenin PCR analysis. In summary, long-term spaceflight in microgravity causes significant atrophy and degeneration of the femoral Quadriceps muscle group, and it may interfere with muscle regenerative processes by inducing apoptosis in newly-formed myofibrils during their differentiation phase.

Grigoryan, E. N.↗

Detectability of extrasolar planetary transits

Precise stellar photometry can be used to detect other planetary systems. However, the intrinsic variability of stellar luminosity imposes a fundamental limit on the sensitivity of this method. Based on recent precise solar observations made from the Solar Maximum Mission satellite, it appears that the detection of earth-sized planets will be marginal during periods of high stellar activity. However, with a suitable photometer larger planets should be readily detectable even in the presence of stellar activity equal to that of the sun at the peak of its sunspot cycle. The high precision, multiple-star photometric system required to detect planets in other stellar systems could be used to monitor flares, starspots, and global oscillations.

Borucki, W. J.↗

Fermi -LAT follow-up observations in seven years of real-time high-energy neutrino alerts

The realtime program for high-energy neutrino track events detected by the IceCube South Pole Neutrino Observatory releases alerts to the astronomical community with the goal of identifying electromagnetic counterparts to astrophysical neutrinos. Gamma-ray observations from theFermi-Large Area Telescope (LAT) enabled the identification of the flaring gamma-ray blazar TXS 0506+056 as a likely counterpart to the neutrino event IC-170922A. By continuously monitoring the gamma-ray sky,Fermi-LAT plays a key role in the identification of candidate counterparts to realtime neutrino alerts. In this paper, we present theFermi-LAT strategy for following up high-energy neutrino alerts applied to seven years of IceCube data. Right after receiving an alert, a search is performed in order to identify gamma-ray activity from known and newly detected sources that are positionally consistent with the neutrino localization. In this work, we study the population of blazars found in coincidence with high-energy neutrinos and compare them to the full population of gamma-ray blazars detected byFermi-LAT. We also evaluate the relationship between the neutrino and gamma-ray luminosities, finding different trends between the two blazar classes BL Lacs and flat-spectrum radio quasars.

Astronomy & Astrophysics↗

The complete Einstein Observatory X-ray survey of the Orion Nebula region.

We have analyzed archival Einstein Observatory images of a roughly 4.5 square degree region centered on the Orion Nebula. In all, 245 distinct X-ray sources have been detected in six High Resolution Imager (HRI) and 17 Imaging Proportional Counter (IPC) observations. An optical database of over 2700 stars has been assembled to search for candidate counterparts to the X-ray sources. Roughly half the X-ray sources are identified with a single Orion Nebula cluster member. The 10 main-sequence O6-B5 cluster stars detected in Orion have X-ray activity levels comparable to field O and B stars. X-ray emission has also been detected in the direction of four main-sequence late-B and early-A type stars. Since the mechanisms producing X-rays in late-type coronae and early-type winds cannot operate in the late-B and early-A type atmospheres, we argue that the observed X-rays, with L(sub X) approximately = 3 x 10(exp 30) ergs/s, are probably produced in the coronae of unseen late-type binary companions. Over 100 X-ray sources have been associated with late-type pre-main sequence stars. The upper envelope of X-ray activity rises sharply from mid-F to late-G, with L(sub x)/L(sub bol) in the range 10(exp -4) to 2 x 10(exp -3) for stars later than approximately G7. We have looked for variability of the late-type cluster members on timescales of a day to a year and find that 1/4 of the stars show significantly variable X-ray emission. A handful of the late-type stars have published rotational periods and spectroscopic rotational velocities; however, we see no correlation between X-ray activity and rotation. Thus, for this sample of pre-main-sequence stars, the large dispersion in X-ray activity does not appear to be caused by the dispersion in rotation, in contrast with results obtained for low-mass main-sequence stars in the Pleiades and pre-main-sequence stars in Taurus-Auriga.

Gagne, Marc↗

PheniX: A New Vision for the Hard X-ray Sky

We are proposing a mission devoted to high energy X-ray astronomy that is based on a focusing telescope operating in the 1-200 keV energy range but optimized for the hard X-ray range. The main scientific topics concern: Physics of compact objects: The proximity of compact objects provides a unique laboratory to study matter and radiation in extreme conditions of temperature and density in strong gravitational environment. The emission of high energy photons from these objects is far from being understood. The unprecedented sensitivity in the high energy domain will allow a precise determination of the non-thermal processes at work in the vicinity of compact objects. The full 1-200 keV energy coverage will be ideal to disentangle the emission processes produced in the spacetime regions most affected by strong-gravity, as well as the physical links: disk-thermal emission-iron line-comptonisation-reflection-non-thermal emission-jets. Neutron stars-magnetic field-cyclotron lines: Time resolved spectroscopy (and polarimetry) at ultra-high sensitivity of AXP, milliseconds pulsars and magnetars will give new tools to study the role of the synchrotron processes at work in these objects. Cyclotron lines-direct measurement of magnetic filed-equation of state constraints-short bursts-giant flares could all be studied with great details. AGN: The large sensitivity improvement will provide detailed spectral properties of the high energy emission of AGN's. This will give a fresh look to the connection between accretion and jet emission and will provide a new understanding of the physical processes at work. Detection of high-redshift active nuclei in this energy range will allow to introduce an evolutionary aspect to high-energy studies of AGN, probing directly the origin of the Cosmic X-ray Background also in the non-thermal range (> 20 keV). Element formation-Supernovae: The energy resolution achievable for this mission (<0.5 keV) and a large high energy effective area are ideally suited for the 44Ti line study (68 and 78 keV). This radioactive nuclei emission will give an estimate of their quantities and speed in their environment. In addition the study of the spatial structure and spectral emission of SNR will advance our knowledge of the dynamics of supernovae explosions, of particles acceleration mechanisms and how the elements are released in the interstellar medium. Instrumental design: The progress of X-ray focusing optics techniques allows a major step in the instrumental design: the collecting area becomes independent of the detection area. This drastically reduces the instrumental background and will open a new era. The optics will be based on depth-graded multi-layer mirrors in a Wolter I configuration. To obtain a significant effective area in the hundred of keV range a focal length in the 40-50 meters range (attainable with a deployable mast) is needed. In addition such a mission could benefit from recent progress made on mirror coating. We propose to cover the 1-200 keV energy range with a single detector, a double-sided Germanium strip detector operating at 80 K. The main features will be: (a) good energy resolution (.150 keV at 5 keV and <.5 keV at 100 keV), (b) 3 dimensional event localization with a low number of electronic chains, (c) background rejection by the 3D localization, (d) polarisation capabilities in the Compton regime.

PHENIX↗

Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in Penicillium expansum and Penicillium chrysogenum

Penicillium expansum is a ubiquitous pathogenic fungus that causes blue mold decay of apple fruit postharvest, and another member of the genus, Penicillium chrysogenum, is a well-studied saprophyte valued for antibiotic and small molecule production. While these two fungi have been investigated individually, a recent discovery revealed that P. chrysogenum can block P. expansum-mediated decay of apple fruit. To shed light on this observation, we conducted a comparative genomic, transcriptomic, and metabolomic study of two P. chrysogenum (404 and 413) and two P. expansum (Pe21 and R19) isolates. Global transcriptional and metabolomic outputs were disparate between the species, nearly identical for P. chrysogenum isolates, and different between P. expansum isolates. Further, the two P. chrysogenum genomes revealed secondary metabolite gene clusters that varied widely from P. expansum. This included the absence of an intact patulin gene cluster in P. chrysogenum, which corroborates the metabolomic data regarding its inability to produce patulin. Additionally, a core subset of P. expansum virulence gene homologues were identified in P. chrysogenum and were similarly transcriptionally regulated in vitro. Molecules with varying biological activities, and phytohormone-like compounds were detected for the first time in P. expansum while antibiotics like penicillin G and other biologically active molecules were discovered in P. chrysogenum culture supernatants. Our findings provide a solid omics-based foundation of small molecule production in these two fungal species with implications in postharvest context and expand the current knowledge of the Penicillium-derived chemical repertoire for broader fundamental and practical applications.

Bartholomew, Holly P. (ORCID:0000000292726399)↗

On the Hunt for Detectable Biosignatures in Jezero Crater: What to Look for and Where

Introduction: The Perseverance rover, which is currently exploring Jezero crater on Mars, is equipped with seven instruments that allow for observation of textures, minerals, color, structure, and chemistry of rocks and sediments in order to search for signs of ancient life, understand the geologic history of the crater, and identify candidates for sample return (Farley et al. 2020). The first of these aims includes the direct detection of potential biosignatures, including textures, organic molecules, minerals, and elemental chemistries that are of biogenic origin (Mustard et al. 2013). The presence of these biosignatures will be constrained by the habitability of the local region, the preservation potential of the host rocks, and the sensitivity of the instrument suite, and their biogenicity will be investigated after return to Earth as part of the Mars Sample Return campaign. Here, we examine key targets on the three planned campaigns, potential biosignatures that may be present, and the capabilities of key rover instruments. High Potential Biosignature Sites in Jezero: To date, measurements have been made on multiple sites that both contain minerals known in terrestrial settings to preserve biosignatures and likely were habitable settings (Williford et al. 2021). Two examples include the fine-grained rocks at the base of the delta fan and the NW inner margin of the crater. Fine-grained Rocks at Base of Delta Fan. Fine-grained, clay-bearing rocks may have been deposited as muddy lake sediments that could have hosted life and preserved biosignatures settling out of the water column. The report of organic molecules by the Curiosity rover in the Sheepbed mudstone and Murray formation has highlighted this site in particular. Potential biosignatures in mudstones, especially those rich in silica (McMahon et al. 2018), microbialites and complex organics. NW Inner Margin of Crater. This unit, located along the inner margin of the crater, contains strong carbonate signatures and may have been the littoral zone of a lake (Horgan et al. 2020). The potential biosignatures here include microfossils, microbialites, biominerals, and complex organics. Detectability of Biosignatures by the Mars 2020 Instrument Suite: The Scanning Habitable Environments with Raman and Luminescence for Organics and Chemicals (SHERLOC) instrument comprises a Deep UV spectrometer, context imager, and color camera to generate spatially resolved chemical maps (Bhartia et al. 2020). It is sensitive to trace organics as well as a range of minerals and can detect native fluorescence from aromatic organics; the WATSON and ACI cameras can be used to observe morphologies such as stromatolitic laminations or filaments ranging from the tens of micron to millimeter scale. SHERLOC can detect organics that may be present in either of the high potential biosignature targets, as well as detect carbonates in the latter. However, the presence of high amounts of iron, such as in iron-rich clays, would cause attenuation of spectral response through UV absorption. The Planetary Instrument for X-ray Lithochemistry (PIXL) comprises an X-ray fluorescence spectrometer and camera that can scan rock surfaces to generate elemental maps (Allwood et al. 2020). PIXL can detect chemical biosignatures such as spatial variations of elemental abundances that may have resulted from biological activity. PIXL would be particularly useful in detecting fine textures and elemental chemistries in either high potential biosignature target, but cannot directly detect minerals such as carbonate. The SuperCam instrument performs three types of spectroscopy, color imaging, and acoustic recording to remotely examine elemental composition, minerals, organics, and textures (Maurice et al. 2021). Using laser induced breakdown spectroscopy and time resolved luminescence spectroscopy, SuperCam can detect major elemental building blocks of organics (i.e., C, H, N, O, P, S) and conjugated organic structures, respectively, which may be found in either site. While in other contexts, luminescence is a useful tool for biosignature identification, luminescence generated by the 532 nm laser may obscure the Raman signal. Conclusion: The three instruments discussed can be used collaboratively to establish the presence of potential biosignatures in samples. These high-priority samples may then be returned to Earth for detailed laboratory analysis.

S. Sharma↗

Airborne, Direct-Detection, 2-μm Triple-Pulse IPDA Lidar for Simultaneous and Independent Atmospheric Water Vapor and Carbon Dioxide Active Remote Sensing

Atmospheric water vapor and carbon dioxide are important greenhouse gases that significantly contribute to the global radiation budget on Earth. A 2-micron triple-pulse, Integrated Path Differential Absorption (IPDA) lidar instrument for ground and airborne atmospheric carbon dioxide and water vapor concentration measurements using direct detection was developed at NASA Langley Research Center. This active remote sensing instrument provides an alternate approach with significant advantages for measuring atmospheric concentrations of the gases. A high energy pulsed laser transmitter approach coupled with sensitive receiver detection provides a high-precision measurement capability by having a high signal-to-noise ratio. This paper presents the concept, development, integration and testing of the 2-micron triple-pulse IPDA. The integration includes the various IPDA transmitter, receiver and data acquisition subsystems and components. Ground and airborne testing indicated successful operation of the IPDA lidar.

Refaat, Tamer F.↗

Provider of Services for Urban Air Mobility (PSU) Prototype Simulation (X5) Final Report

Urban Air Mobility (UAM) is a new air transportation service concept to carry passengers or cargo in metropolitan areas, leveraged by innovative aircraft and air traffic automation technologies. NASA has conducted a series of simulations, called the X-series simulation, to evaluate the UAM concept of operations and support the development of airspace procedures and services for UAM operations. The simulation called “X5” was conducted in 2023 to test a Provider of Services for UAM (PSU) prototype developed by NASA for UAM flight planning, strategic conflict management support, and data exchange between UAM operators. In this simulation, two strategic conflict management capabilities, Demand-Capacity Balancing and Sequencing and Scheduling, were further investigated. This document describes the UAM system architecture modeled, the X5 simulation environment to be executed (e.g., traffic scenario and UAM airspace construct), and the strategic conflict management processes developed and evaluated in this study. Then, the simulation results are provided using several system performance metrics, such as the number of operations planned and activated, demand-capacity imbalances detected and resolved, and pre-departure delays. Based on these metrics, the test findings and lessons learned from this simulation are discussed. NASA developed a PSU prototype as part of a reference implementation of UAM system architecture and evolved strategic conflict management capabilities for UAM operations from the previous collaborative simulations with industry partners. Below is the summary of the achievements: - Aligned NASA’s UAM reference architecture with the FAA’s UAM ConOps notional architecture - Extended UAM airspace management capabilities to include 1) Demand-Capacity Balancing (DCB) to ensure operators coordinate planned usage of shared vertiports, and 2) Sequencing and Scheduling (S&S) at UAM corridor entry and exit points to help facilitate an orderly flow of traffic - Defined the PSU information exchange APIs and requirements towards informing industry standards - Developed and tested a NASA PSU prototype as reference implementation to validate the requirements and APIs - Developed a prototype service connecting NASA’s PSU and the FAA system for testing future PSU-ATM interface requirements - Tested NASA-developed assumptions for UAM operations such as airspace design, procedures, vehicle performance, and strategic conflict management methods to inform future Cooperative Operating Practices (COPs) development with industry - Evaluated system performance metrics such as number of simultaneous operations and ground delays that can help define system-level requirements. The simulation results showed that the UAM traffic demand could be managed to minimize the needs of tactical separation provision with ground delays assigned by DCB and S&S. These accomplishments and the lessons learned from the PSU Prototype X5 simulation activities will be valuable inputs for the Air Mobility Pathfinders (AMP) project, which is NASA’s new project to create and evaluate a reference architecture for safe, secure, and scalable UAM operations.

Simulation↗

A Notional Artemis Lunar Surface Exploration Package (ArLSEP) based on the Gandalf Staff Platform

Introduction: The Artemis program is planning to deliver crew and cargo to the lunar surface, but there is no current package for supporting lunar in-struments and experiments similar to the Apollo Lunar Surface Exploration Package (ALSEP). This abstract provides a possible concept for such a package using the Gandalf Staff Platform as a common core. Gandalf Staff: The Gandalf Staff is an early prototype system developed over FY’21/FY’22 using NASA Science Technology Mission Directorate (STMD) Center Information Fund (CIF) grants to de-sign, build and test “proof-of-concept” components. These components include a 24v battery powered monopole that powers a suite of subsystems, including a Graphical User Interface (GUI) for crew, surface voice and data communications, Lunar Search and Rescue (LunaSAR) navigation and communications, LiDAR, field site external lighting, 360-degree camera, and a geothermal instrument for measuring sub-surface temperature gradient. The staff can be carried independently by an Extra-Vehicular Activity (EVA) astronaut, or can be mounted into a tripod for “hands free” support at a surface site being investigated. The staff can be attached to an external solar array and power storage system for long-duration operations. [1,2] ALSEP: An ASLEP flew on each mission Apollo 12 to Apollo 17. For Apollo 11, a simplified packaged called the Early Apollo Scientific Experiments Pack-age (EASEP) was flown. Each package included a “Central Station” that provided the power and communications connected to a variety of instruments and sensors. The power was provided by a Radioisotope Thermoelectric Generator (RTG) fueled by Plutoni-um-238 generating 70 watts of power (initially, decayed over time) [3]. The communications system provide for direct to Earth data transfer from the lunar surface. Each pack-age was stowed externally in the Lunar Module (LM) Scientific Equipment (SEQ) bay with a mass up to 163 kg (Apollo 17). The crew unloaded the ALSEP from the LM and deployed the instruments on the lunar surface. Although designed to operate for only 1 year, many sites operated for up to 8 years successfully [4]. The Active Seismic Experiment (ASE) included 3 geophones for detecting seismic waves created by mortars and thumpers deployed by the crew. Other active experiments measured the lunar atmosphere, the heat flow in the subsurface, the lunar gravity and potential gravity waves, the lunar magnetic field, the solar wind and plasma interactions in cislunar space. Passive experiments included collectors for dust and cosmic rays, and retroreflectors for precise measurements of distance using a laser from Earth. The ALSEP program continues to generate insights into lunar formation and evolution. ArLSEP Concepts: The lunar surface science package for the Artemis program will hopefully exceed the capability of the ALSEP. There are multiple issues for discussion leading to the design of a new ArLSEP, needing requirements definition from the science community, NASA mission architecture, and NASA budget planners. 1. Delivery Mechanism Two possible projects currently provide capability to deliver scientific cargo to the lunar surface: 1) the Commercial Lunar Payload Services (CLPS) [5] and the Human Landing System (HLS) [6, 7]. Each project is controlled by a different organization within NASA and budgeted with different criteria although both support lunar exploration. The HLS system delivers crew (and potentially cargo) to human landing sites. If an ArLSEP is “predeployed” to such a site, the design must include power (either from the vehicle or independently) to keep the electronics functioning until deployed by the crew. If an ArLSEP is delivered on a vehicle after the crew is present on the lunar surface, safety protocols require adequate distance from the humans for impact from descent propelled sur-face regolith ejecta. This distance can not exceed the capability of the crew to walk (if no rover) to the vehicle for ArLSEP deployment. 2. Overall Guidelines The general design of ArLSEP will likely follow the ALSEP with a common system for communications and power; however, significant architecture differences between Apollo and Artemis exist. Power: The RTG will not be available for early Artemis missions nor likely follow-on Lunar Exploration Transportation Services (LETS) missions [8]. Thus, ArLSEP power must be supplied by solar arrays with sufficient battery capability to “keep alive” necessary electronics during any lunar surface eclipse period. Communication: The Artemis program is developing a series of communications satellites for lunar orbit to provide surface transmission of data and voice to Earth. Called “LunaNET”, this network is component useful for ArLSEP since south polar locations may not always have direct “line-of-sight” to Earth [9]. 3. Concept of Operations (ConOps) The general ConOps for ArLSEP is to deliver the package to lunar surface before the crew arrives, and then have the crew deploy the package after some period of time. This requires coordinated design (for power systems) and launch window (for schedule) on both the cargo and crew missions. Once the ArLSEP is deployed, it will operate autonomously for a number of years. It should be designed to be EVA compatible for crew maintenance and upgrade. 4. Notional Design (for discussion purpose only) The landing site near the South Pole is expected to have no eclipse cycle exceeding 5 days, so the “keep alive” power is 144 hours (6 days to include margin). A 12v ArLSEP will use rechargeable LiFePO4 cells, which are common in the Electric Vehicle (EV) industry. With a current of 5 amps and a 125 watt system, the mass is about 90kg. The comm. system and structure adds another 10kg, thus the “Central Station” is approximately 100kg. The solar power is collected on four arrays (each 2m above the surface), and the entire ArLSEP is designed to stow in a 2m x 1m x 1m volume. The experiment and instrument design will vary for each installation and add mass to the total (although they are expected to fit within the 2m3 volume). Seismic wave generation will likely not be provided with mortars, thus an electric “thumper” will be required. Active instruments such as imaging systems and sensing instruments will benefit from the additional power and communication capability provided by ArLSEP. Passive systems such as retroreflectors, witness plates, and cosmic dust collectors can be added to either the landing vehicle and/or the ArLSEP. With repeated HLS missions to the same human site, the ArLSEP can be expanded and easily maintained for long duration science collection on the lunar surface.

ALSEP↗

The Atacama Cosmology Telescope: Systematic Transient Search of Single Observation Maps

We conduct a systematic search for astrophysical transients using data from the Atacama Cosmology Telescope. The data were taken from 2017 to 2022 in three frequency bands spanning 77 to 277 GHz. In this paper, we present a pipeline for transient detection using single-observation maps where each pixel of a map contains one observation with an integration time of approximately 4 minutes. We detect 34 transient events at 27 unique locations. All but two of the transients are associated with Galactic stars and exhibit a wide range of properties. We also detect an event coincident with the classical nova YZ Ret and one event consistent with a flaring active galactic nucleus. We notably do not detect any reverse shock emission from gamma-ray bursts, a nondetection that may be in tension with current models.

79 ASTRONOMY AND ASTROPHYSICS↗

Active Learning with Rationales for Identifying Operationally Significant Anomalies in Aviation

A major focus of the commercial aviation community is discovery of unknown safety events in flight operations data. Data-driven unsupervised anomaly detection methods are better at capturing unknown safety events compared to rule-based methods which only look for known violations. However, not all statistical anomalies that are discovered by these unsupervised anomaly detection methods are operationally significant (e.g., represent a safety concern). Subject Matter Experts (SMEs) have to spend significant time reviewing these statistical anomalies individually to identify a few operationally significant ones. In this paper we propose an active learning algorithm that incorporates SME feedback in the form of rationales to build a classifier that can distinguish between uninteresting and operationally significant anomalies. Experimental evaluation on real aviation data shows that our approach improves detection of operationally significant events by as much as 75% compared to the state-of-the-art. The learnt classifier also generalizes well to additional validation data sets.

anomaly detection↗

PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation

PARP1 detection of DNA strand breaks allosterically leads to PARP1 synthesis of poly(ADP-ribose) modifications that signal DNA damage. HPF1 engages activated PARP1 to control modification site selection. Understanding of the mechanism of DNA break detection and catalytic activation is incomplete, due largely to limited structural information for full-length PARP1. Here, single-particle cryo-EM provides views of the full complement of PARP1 domains engaging a DNA single-strand break in the presence of HPF1 and a fragment of binding partner Timeless. Cryo-EM, single-molecule DNA dynamics, and small-angle X-ray scattering analysis indicate that PARP1 remains dynamic even when the multi-domain structure is organized on a DNA break, with the minimal catalytic region displaying high mobility relative to domains engaging damage. We propose that the organization of PARP1 domains on a DNA break releases a tethered, constitutively active catalytic region to modify molecules in a radius surrounding the DNA break site.

59 BASIC BIOLOGICAL SCIENCES↗

Expansion of the Fast Neutron Hodoscope at TREAT to Support Fuel Safety Experiments

In 2024 the Fuel Motion Monitoring System (FMMS), or Hodoscope, at the Transient Reactor Test Facility, is being expanded from 96 viewing channels to 192 viewing channels, effectively doubling the FMMS field of view. Here, this increase in capability will allow the FMMS to support larger scale fuel tests, encompassing height-of-core test devices, test devices with multi-pin fuel assemblies, and test devices with recirculating coolant flow. Work supporting the expansion included refurbishing 96 additional proton recoil scintillator (PRS) detectors, doubling the data acquisition system (DAS) installed architecture, improving time synchronization in the DAS, and new research to measure the PRS detector energy-dependent, fast-neutron detection efficiency. In addition, laboratory activities have produced an improved benchtop testing capability for assessing the DAS, time synchronization, and external start triggering, along with an updated capability to scan PRS detectors to develop a preliminary flat-field normalization prior to deployment to TREAT.

46 - INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AN↗