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At least 55 records · Page 3

Preparing for the next pandemic via transfer learning from existing diseases with hierarchical multi-modal BERT: a study on COVID-19 outcome prediction

Abstract Developing prediction models for emerging infectious diseases from relatively small numbers of cases is a critical need for improving pandemic preparedness. Using COVID-19 as an exemplar, we propose a transfer learning methodology for developing predictive models from multi-modal electronic healthcare records by leveraging information from more prevalent diseases with shared clinical characteristics. Our novel hierarchical, multi-modal model ( $${\textsc {TransMED}}$$ T R A N S MED ) integrates baseline risk factors from the natural language processing of clinical notes at admission, time-series measurements of biomarkers obtained from laboratory tests, and discrete diagnostic, procedure and drug codes. We demonstrate the alignment of $${\textsc {TransMED}}$$ T R A N S MED ’s predictions with well-established clinical knowledge about COVID-19 through univariate and multivariate risk factor driven sub-cohort analysis. $${\textsc {TransMED}}$$ T R A N S MED ’s superior performance over state-of-the-art methods shows that leveraging patient data across modalities and transferring prior knowledge from similar disorders is critical for accurate prediction of patient outcomes, and this approach may serve as an important tool in the early response to future pandemics.

59 BASIC BIOLOGICAL SCIENCES↗

Review and Modeling of Integrated Energy Systems with Nuclear Reactor Coupled Desalination and District Heating

Detailed reviews of a past advanced nuclear reactor based integrated energy system, as well as other nuclear reactor and fossil fuel based integrated energy systems have been performed for this work. Review of the utilization of heat from nuclear reactors for various applications and cogeneration has been done. The heat can be utilized by extraction of the steam from the turbine while the steam is still at a desired temperature. While use of nuclear process heat for district heating in countries like Finland, France, China, Poland, and elsewhere is discussed, more focus of the review has been given on nuclear desalination processes. Integrated energy systems (IES) where distinct types of reactors like PWR, BWR, sodium cooled fast reactor, heavy water reactor and other advanced reactors are coupled with various nuclear desalination processes like multi-effect distillation (MED), multi-stage flashing (MSF) and reverse osmosis (RO) methods have been discussed. The nuclear desalination plant at Aktau has been discussed in more detail due to its decades of successful operation. The IES of the Aktau plant coupled with 5-effect MED desalination plant has been taken as a reference for modeling the Open Modelica (OM) based IES of this work. Here, the OM IES model shows good agreement with the MED plant output of Aktau and can be extended for future applications of IES.

42 ENGINEERING↗

Remote Sensing Approach for Monitoring Tree Health Adjacent to Transmission Corridors

This study presents an initial proof-of-concept for a satellite-based remote sensing approach to identify and monitor potential areas of poor tree health across the entire BPA service territory on an annual basis. We tested three variants of “delta peak NDVI” ( ΔPN ) change detection metrics that express interannual variation in primary productivity relative to a baseline by comparing ΔPN values for known insect/disease disturbances and nearby reference locations. All three metrics showed promise for detecting poor tree health in the year during disturbance, but the metric based on the difference from the long-term (2016-2024) median ( Δ Med PN ) was preferred due to its responsiveness to change in the years during and after disturbance, resilience to interannual variation, and ease of interpretation as being above or below normal. Comparison of Δ Med PN grouped by relative severity of disturbance indicated it was not sensitive enough to detect “low” severity disturbances, as mapped by USGS’s LANDFIRE program, but could distinguish “moderate” and “high” severity disturbances from reference locations. These findings informed selection of a threshold for Δ Med PN , which was combined with areas exhibiting negative NDVI to map potential areas of concern. Visual inspection of before/after high-resolution imagery and NDVI time series showed that many areas of concern aligned with visible signs of defoliation and die-off as well as other types of disturbance (e.g., landslides, logging, road grading, flooding). Some areas of concern are thought to be false detections caused by persistent shadow, and some could not be explained with visual inspection due to spatiotemporal limitations of before/after imagery. In summary, our approach shows promise for large-scale monitoring of tree health adjacent to BPA transmission lines, but additional work is recommended to improve model sophistication and remove noise.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Implementing Chiral Three-Body Forces in Terms of Medium-Dependent Two-Body Forces

Three-nucleon (3N) forces are an indispensable ingredient for accurate few-body and many- body nuclear structure and reaction theory calculations. While the direct implementation of chiral 3N forces can be technically very challenging, a simpler approach is given by employing instead a medium-dependent NN interaction V med that reflects the physics of three-body forces at the two-body normal-ordered approximation. We review the derivation and construction of Vmed from the chiral 3N interaction at next-to-next-to-leading order (N2LO), consisting of a long-range 2π-exchange term, a mid-range 1π-exchange component and a short-range contact-term. Several applications of V med to the equation of state of cold nuclear and neutron matter, the nucleon single-particle potential in nuclear matter, and the nuclear quasiparticle interaction are discussed. We also explore differences in using local vs. nonlocal regulating functions on 3N forces and make direct comparisons to exact results at low order in perturbation theory expansions for the equation of state and single-particle potential. We end with a discussion and numerical calculation of the in-medium NN potential V med from the next-to-next-to-next-to-leading order (N3LO) chiral 3N force, which consists of a series of long-range and short-range terms.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Mean Estimate Distances for Galaxies with Multiple Estimates in NED-D

Numerous research topics rely on an improved cosmic distance scale (e.g., cosmology, gravitational waves) and the NASA/IPAC Extragalactic Database of Distances (NED-D) supports those efforts by tabulating multiple redshift-independent distances for 12,000 galaxies (e.g., Large Magellanic Cloud (LMC) zero-point). Six methods for securing a mean estimate distance (MED) from the data are presented (e.g., indicator and Decision Tree). All six MEDs yield surprisingly consistent distances for the cases examined, including for the key benchmark LMC and M106 galaxies. The results underscore the utility of the NED-D MEDs in bolstering the cosmic distance scale and facilitating the identification of systematic trends.

79 ASTRONOMY AND ASTROPHYSICS↗

Implementation and evaluation of the unified stomatal optimization approach in the Functionally Assembled Terrestrial Ecosystem Simulator (FATES)

Abstract. Stomata play a central role in regulating the exchange of carbon dioxide and water vapor between ecosystems and the atmosphere. Their function is represented in land surface models (LSMs) by conductance models. The Functionally Assembled Terrestrial Ecosystem Simulator (FATES) is a dynamic vegetation demography model that can simulate both detailed plant demographic and physiological dynamics. To evaluate the effect of stomatal conductance model formulation on forest water and carbon fluxes in FATES, we implemented an optimality-based stomatal conductance model – the Medlyn (MED) model – that simulates the relationship between photosynthesis (A) and stomatal conductance to water vapor (gsw) as an alternative to the FATES default Ball–Woodrow–Berry (BWB) model. To evaluate how the behavior of FATES is affected by stomatal model choice, we conducted a model sensitivity analysis to explore the response of gsw to climate forcing, including atmospheric CO2 concentration, air temperature, radiation, and vapor pressure deficit in the air (VPDa). We found that modeled gsw values varied greatly between the BWB and MED formulations due to the different default stomatal slope parameters (g1). After harmonizing g1 and holding the stomatal intercept parameter (g0) constant for both model formulations, we found that the divergence in modeled gsw was limited to conditions when the VPDa exceeded 1.5 kPa. We then evaluated model simulation results against measurements from a wet evergreen forest in Panama. Results showed that both the MED and BWB model formulations were able to capture the magnitude and diurnal changes of measured gsw and A but underestimated both by about 30 % when the soil was predicted to be very dry. Comparison of modeled soil water content from FATES to a reanalysis product showed that FATES captured soil drying well, but translation of drying soil to modeled physiology reduced the models' ability to match observations. Our study suggests that the parameterization of stomatal conductance models and current model response to drought are the critical areas for improving model simulation of CO2 and water fluxes in tropical forests.

54 ENVIRONMENTAL SCIENCES↗

Atlas of quasar energy distributions

We present an atlas of the spectral energy distributions (SEDs) of normal, nonblazar, quasars over the whole available range (radio to 10 keV X-rays) of the electromagnetic spectrum. The primary (UVSX) sample includes 47 quasars for which the spectral energy distributions include X-ray spectral indices and UV data. Of these, 29 are radio quiet, and 18 are radio loud. The SEDs are presented both in figures and in tabular form, with additional tabular material published on CD-ROM. Previously unpublished observational data for a second set of quasars excluded from the primary sample are also tabulated. The effects of host galaxy starlight contamination and foreground extinction on the UVSX sample are considered and the sample is used to investigate the range of SED properties. Of course, the properties we derive are influenced strongly by the selection effects induced by quasar discovery techniques. We derive the mean energy distribution (MED) for radio-loud and radio-quiet objects and present the bolometric corrections derived from it. We note, however, that the dispersion about this mean is large (approximately one decade for both the infrared and ultraviolet components when the MED is normalized at the near-infrared inflection). At least part of the dispersion in the ultraviolet may be due to time variability, but this is unlikely to be important in the infrared. The existence of such a large dispersion indicates that the MED reflects only some of the properties of quasars and so should be used only with caution.

Elvis, Martin↗

Mars 2020 Entry, Descent, and Landing Instrumentation 2 (MEDLI2) Sensor Suite

The Mars 2020 Entry, Descent, and Landing Instrumentation 2 (MEDLI2) sensor suite seeks to address the aerodynamic, aerothermodynamic, and thermal protection system (TPS) performance issues during atmospheric entry, descent, and landing of the Mars 2020 mission. Based on the highly successful instrumentation suite that flew on Mars Science Laboratory (MEDLI), the new sensor suite expands on the types of measurements and also seeks to answer questions not fully addressed by the previous mission. Sensor Package: MEDLI2 consists of 7 pressure transducers, 17 thermal plugs, 2 heat flux sensors, and one radiometer. The sensors are distributed across both the heatshield and backshell, unlike MEDLI (the first sensor suite), which was located solely on the heat-shield. The sensors will measure supersonic pressure on the forebody, a pressure measurement on the aftbody, near-surface and in-depth temperatures in the heatshield and backshell TPS materials, direct total heat flux on the aftbody, and direct radiative heating on the aftbody. Instrument Development: The supersonic pressure transducers, the direct heat flux sensors, and the radiometer all were tested during the development phase. The status of these sensors, including the piezo-resistive pressure sensors, will be presented. The current plans for qualification and calibration for all of the sensors will also be discussed. Post-Flight Data Analysis: Similar to MEDLI, the estimated flight trajectory will be reconstructed from the data. The aerodynamic parameters that will be reconstructed will be the axial force coefficient, freestream Mach number, base pressure, atmospheric density, and winds. The aerothermal quantities that will be determined are the heatshield and backshell aero-heating, turbulence transition across the heatshield, and TPS in-depth performance of PICA. By directly measuring the radiative and total heat fluxes on the back-shell, the convective portion of the heat flux will be estimated. The status of the current tools to perform the post-flight data analysis will be presented, along with plans for model improvements.

Hwang, Helen H.↗

Mars 2020 Entry, Descent, and Landing Instrumentation 2 (MEDLI2) Sensor Suite

The Mars 2020 Entry, Descent, and Landing Instrumentation 2 (MEDLI2) sensor suite seeks to address the aerodynamic, aerothermodynamic, and thermal protection system (TPS) performance issues during atmospheric entry, descent, and landing of the Mars 2020 mission. Based on the highly successful instrumentation suite that flew on Mars Science Laboratory (MEDLI), the new sensor suite expands on the types of measurements and also seeks to answer questions not fully addressed by the previous mission. Sensor Package: MEDLI2 consists of 7 pressure transducers, 17 thermal plugs, 2 heat flux sensors, and one radiometer. The sensors are distributed across both the heatshield and backshell, unlike MEDLI (the first sensor suite), which was located solely on the heat-shield. The sensors will measure supersonic pressure on the forebody, a pressure measurement on the aftbody, near-surface and in-depth temperatures in the heatshield and backshell TPS materials, direct total heat flux on the aftbody, and direct radiative heating on the aftbody. Instrument Development: The supersonic pressure transducers, the direct heat flux sensors, and the radiometer all were tested during the development phase. The status of these sensors, including the piezo-resistive pressure sensors, will be presented. The current plans for qualification and calibration for all of the sensors will also be discussed. Post-Flight Data Analysis: Similar to MEDLI, the estimated flight trajectory will be reconstructed from the data. The aerodynamic parameters that will be reconstructed will be the axial force coefficient, freestream Mach number, base pressure, atmospheric density, and winds. The aerothermal quantities that will be determined are the heatshield and backshell aero-heating, turbulence transition across the heatshield, and TPS in-depth performance of PICA. By directly measuring the radiative and total heat fluxes on the back-shell, the convective portion of the heat flux will be estimated. The status of the current tools to perform the post-flight data analysis will be presented, along with plans for model improvements.

Hwang, Helen↗

Mars Science Laboratory Heatshield Flight Data Analysis

NASA Mars Science Laboratory (MSL), which landed the Curiosity rover on the surface of Mars on August 5th, 2012, was the largest and heaviest Mars entry vehicle representing a significant advancement in planetary entry, descent and landing capability. Hypersonic flight performance data was collected using MSLs on-board sensors called Mars Entry, Descent and Landing Instrumentation (MEDLI). This talk will give an overview of MSL entry and a description of MEDLI sensors. Observations from flight data will be examined followed by a discussion of analysis efforts to reconstruct surface heating from heatshields in-depth temperature measurements. Finally, a brief overview of MEDLI2 instrumentation, which will fly on NASAs Mars2020 mission, will be presented with a discussion on how lessons learned from MEDLI data affected the design of MEDLI2 instrumentation.

Mars↗

Inverse Determination of Aeroheating and Charring Ablator Response

The Mars Science Laboratory (MSL) was protected during its Mars atmospheric entry by an instrumented heatshield that used NASA's Phenolic Impregnated Carbon Ablator (PICA). PICA is a lightweight carbon fiber/polymeric resin material that offers excellent performances for protecting probes during planetary entry. The Mars Entry Descent and Landing Instrument (MEDLI) suite on MSL offers unique in-flight validation data for models of atmospheric entry and material response. MEDLI recorded, among others, time-resolved in-depth temperature data of PICA using thermocouple sensors assembled in the MEDLI Integrated Sensor Plugs (MISP). These measurements have been widely used in the literature as a validation benchmark for state-of-the-art ablation codes. The objective of this work is to perform an inverse estimate of the MSL heatshield material properties and aerothermal environment during Mars entry from the MISP flight data.

Aeroheating↗

Heatshield Entry Modeling Using a Design, Analysis, and Optimization Toolbox

The Mars Science Laboratory (MSL) was protected during its Mars atmospheric entry by an instrumented heatshield that used NASA's Phenolic Impregnated Carbon Ablator (PICA). PICA is a lightweight carbon fiber/polymeric resin material that offers excellent performances for protecting probes during planetary entry. The Mars Entry Descent and Landing Instrument (MEDLI) suite on MSL offers unique in-flight validation data for models of atmospheric entry and material response. MEDLI recorded, among others, time-resolved in-depth temperature data of PICA using thermocouple sensors assembled in the MEDLI Integrated Sensor Plugs (MISP). The objective of this work is to showcase the capability of the Design, Analysis, and Optimization of Thermal Protection Materials (DAOTPM) software. DAO-TPM is a Python based framework that works as a link between mission design, aerothermal and radiative environment computation, Thermal Protection Systems (TPS) microstructure analysis, material response and optimization tools. The toolbox has a Graphical User Interface (GUI) that allows the user to build as well as run the various software and utilities used to design, analyze and optimize a heatshield during atmospheric entry.

Meurisse, Jeremie B. E.↗

Charactarization of Thermal Protection Systems

In 2012, NASA's mission of landing the Mars Science Laboratory (MSL) on Mars was successful. MSL was protected by an ablative heatshield of tiled low density material known as PICA (phenolic impregnated carbon ablator). The heatshield was instrumented with MEDLI (MSL Entry Descent Landing Instrument) a suite of sensors & thermocouples at discrete locations in order to monitor the in-depth ablator temperature response and surface pressure. MEDLI was designed and developed by NASA Langley, in partnership with NASA Ames Research Center for the purposes of probing Mars and evaluating the performance of the spacecraft upon entry into the Martian atmosphere. The flight data reduces the uncertainty in engineer models for predicting the response of a spacecraft towards the extreme heating environment of an entry into the Martian atmosphere. MEDLI2 is a part of the Mars 2020 mission and is the next-generation sensor suite for entry, descent, and landing. This data will again help engineers validate their flight models. Additionally, the atmospheric data, can help us understand atmospheric density and winds. This is a critical study for reducing risks to both robotic and future human missions to Mars. Engineered models for Mars 2020 are dependent upon parameters related to the materials response to heating and radiation. In this work, the thermal properties and other measurements of various ablative materials are analyzed to achieve greater utility of the 2012 MEDLI flight data and more accurately determine the parameters being used in Mars 2020. The purpose of this study was to measure specific heat, thermal conductivity, char yield, reflectance as a function of wavelength, and other thermal parameters and optical properties of various ablative materials. CO2(g) at extreme temperatures emits radiation impacting MEDLI2 flight predictions. Emissivity & absorptivity as a function of temperature were calculated from FTIR and UV-Vis data as a means of investigating whether these materials might absorb CO2 radiation upon entry into the Mars atmosphere.

HEEET↗

Determination of Aerothermal Environment and Ablator Material Response Using Inverse Methods

The Mars Science Laboratory (MSL) was protected during entry into the Martian atmosphere by a thermal protection system that used NASA’s Phenolic Impregnated Carbon Ablator (PICA). The heat shield of the probe was instrumented with the Mars Entry Descent and Landing Instrument (MEDLI) suite of sensors. MEDLI Integrated Sensor Plugs (MISP) included thermocouples that measured in-depth temperatures at various locations on the heatshield. The flight data has been used as a benchmark for validating ablation codes within NASA. This work seeks to refine the estimate of the material properties for the MSL heat shield and the aerothermal environment during Mars entry using estimation methods in DAKOTA on the temperature data obtained from MEDLI.

Thornton, John M.↗

Overview of Dragonfly Entry Aerosciences Measurements (DrEAM)

NASA Ames Research Center (ARC) leads the Dragonfly Entry Aerosciences Measurements (DrEAM) project, which is an aeroshell instrumentation suite on the Dragonfly mission that fulfills the Engineering Science Investigation requirement for the New Frontiers mission. NASA ARC is partnering with NASA Langley Research Center (LaRC) and the German Aerospace Center (DLR) to provide a comprehensive sensor suite, including a DLR-provided Data Acquisition System (DAS). DrEAM will provide key aerothermodynamic data and performance analysis for Dragonfly’s forebody and backshell Thermal Protection System (TPS). Titan’s atmosphere predominantly consists of ni-trogen (~98% by mole) with small amounts of me-thane (~2% by mole) and other trace gases. CN is a strong radiator, and is found in nonequilibrium con-centrations for Titan entry. The accurate modeling of nonequilibrium CN radiation has proven to be a diffi-cult task. Prompted by the Huygens mission, many experimental campaigns and analyses were performed to better understand the aerothermal environments experienced by the probe during Titan entry [1]. How-ever, the Huygens probe carried no heatshield instru-mentation. Therefore, the DrEAM sensor suite will sig-nificantly advance the state-of-the-art not only by documenting the environment and performance of Dragonfly’s entry system but also by making key in situ measurements in Titan’s atmosphere for the first time. Aerothermal environments and TPS response will be measured using sensors whose flight heritage is tak-en from the Mars Entry, Descent, and Landing In-strumentation 2 (MEDLI2) thermocouple plugs and the COMbined Aerothermal and Radiometer Sensor (COMARS) suite [2], with the latter supplied by DLR. The MEDLI2 project used embedded thermocouples to directly measure the in-depth TPS temperature-time history at several locations on the heat shield and backshell of the Mars 2020 entry vehicle. These tem-perature measurements, in turn, can be used to infer surface environments via an inverse analysis proce-dure analogous to that used for MEDLI. For DrEAM, the thermocouple plug subsystem will be known as Dragonfly Sensors for Aero-Thermal Reconstruction (DragSTR). On Schiaparelli, the COMARS suite in-cluded three total surface-mounted heat flux sensors, three pressure sensors, and one radiometer. For DrEAM, the COMARS package will be known as the COmbined Sensor System for Titan Atmosphere (COSSTA). Since the methane concentration in the Titan atmos-phere is directly proportional to the radiative heat flux, the COSSTA measurements will be used to reduce the current uncertainty in the methane volume fraction. Atmospheric density measurements and capsule aero-dynamic data will be obtained through the onboard Inertial Measurement Unit (IMU), supplemented by pressure transducers similar to those used by the MEDLI and MEDLI2 projects. The DrEAM pressure sensors will be known as the Dragonfly Atmospheric Flight Transducers. (DrAFT). The pressure measure-ments, when combined with data from the on-board IMU, will allow for reconstruction of such quantities as vehicle Mach number, freestream density, and atmos-pheric winds. DrAFT measurements will enhance Dragonfly trajectory reconstruction and enable a sepa-ration of the aerodynamics from the atmosphere, as was done for MEDLI [3] and is currently in process for the MEDLI2 flight data set.

EDL↗

Objective Structured Clinical Evaluation (OSCE) of an Artificial Intelligence (AI) Clinical Decision Support System (CDSS) Tool

BACKGROUND Objective Structured Clinical Evaluations (OSCEs) have long been established as a robust methodology for summative assessment of clinical skills and decision-making during medical education. The recent integration of Artificial Intelligence (AI) into clinical decision-making processes has prompted the need for novel evaluation frameworks to assess the efficacy and reliability of AI clinical decision support system (CDSS) tools. This abstract outlines the process of quantitatively evaluating a novel CDSS (“Doc in a Box” Google 2024) trained on curated medical spaceflight data in the psychomotor domain as it interfaces with a human volunteer acting as the crew medical officer (CMO). PURPOSE The AI CDSS under review was developed as part of the Lunar Command and Control Interoperability (LuCCI) project, which is intended to address a gap in how Lunar Surface Systems (LSS) would interoperate across multiple programs, commercial partners, and international partners. The project objective is to define, prototype, integrate, and evaluate an interoperable lunar command, control, data, and software reference architecture to enable autonomy and informatics capability through common standards across LSS. A multi-modal AI-based CDSS compatible with Federated LSS will assist clinicians in diagnosing and managing complex medical conditions by providing evidence-based recommendations through predictive analytics. Given the critical role of decision-support as NASA continues to evolve its Earth-independent medical operations (EIMO), it is imperative to ensure that such AI tools perform reliably and align with clinical standards during progressive lunar and Martian exploration class missions. METHODS The OSCE framework, traditionally used for evaluating human clinicians, was adapted to assess the AI tool's decision-making capabilities in simulated clinical scenarios. In this adapted OSCE, the AI CDSS was tested across a series of structured clinical scenarios designed to mimic real-life spaceflight patient cases. These scenarios included a range of conditions and complexities, allowing for comprehensive assessment of the tool's performance. Key evaluation metrics included accuracy of diagnosis, timeliness of decision-making, and appropriate recommendations for therapies. The OSCE was scored by human physician evaluators who assessed the AI's recommendations in comparison with expert clinicians' medical decision making to ensure alignment with best practices and the standard of care. RESULTS Preliminary results indicate that the AI CDSS demonstrated high accuracy in diagnostic recommendations and decision support across various scenarios. However, certain limitations were noted, such as occasional discrepancies in handling complex or nuanced cases that required a more contextual understanding. Additionally, the tool scored higher on the diagnostic portion of the rubric, with lower scores in the therapeutic recommendations. These findings highlight the importance of continuous refinement and validation of AI tools through rigorous evaluation frameworks like the OSCE. The adaptation of OSCEs for AI tools presents several advantages, including a structured and reproducible approach to evaluation, the ability to test AI systems in diverse clinical scenarios, and the opportunity to benchmark AI performance against established clinical standards to permit charting of future progress as aerospace medicine evolves as a discipline. Remaining challenges include ensuring that these evaluations capture the full spectrum of clinical decision-making scenarios that will be confronted by CMOs during missions and adequately reflecting real-world variability of the austere spaceflight environment. CONCLUSION Employing OSCEs to evaluate AI clinical decision support tools offers a promising approach to validating their clinical utility and efficacy. This methodology not only provides insights into the tool's performance but also fosters ongoing improvement and alignment with standard of care practices. Future research should focus on refining these evaluation processes and addressing limitations to enhance the integration of AI tools in clinical spaceflight settings. REFERENCES Scott S, Hearns V, Barker MA. Testing Clinical Skills: A Look at the OSCE and USMLE Clinical Skills Exams. S D Med. 2019 Oct;72(10):451-453. Majumder MAA, Kumar A, Krishnamurthy K, Ojeh N, Adams OP, Sa B. An evaluative study of objective structured clinical examination (OSCE): students and examiners perspectives. Adv Med Educ Pract. 2019 Jun 5;10:387-397. Karam VY, Park YS, Tekian A, Youssef N. Evaluating the validity evidence of an OSCE: results from a new medical school. BMC Med Educ. 2018 Dec 20;18(1):313.

Ariana M Nelson↗

Falling-film heat exchangers used in desalination systems: A review

With growing demand for fresh water, there has been an increasing interest in energy-efficient desalination technologies. Falling-film-based, multi-effect distillation (MED) systems have been extensively deployed world-wide. The performance of such systems heavily depends on the efficiency of the evaporation process. Here, research on falling-film heat exchangers used in desalination systems, especially MED systems, is critically reviewed to assess the state of the technology. The review includes falling-film evaporation mechanisms, system operation, and scaling issues. Finally, opportunities for further application and areas where more research is needed are identified.

42 ENGINEERING↗

Spectroscopy of the T = 2 mirror nuclei 48 Fe/ 48 Ti using mirrored knockout reactions

A sequence of excited states has been established for the first time in the proton-rich nucleus 48 Fe (Z=26, N=22). The technique of mirrored (i.e. analogue) one-nucleon knockout reactions was applied, in which the T z = ±2 mirror pair, 48 Fe/ 48 Ti were populated via one-neutron/one-proton knockout from the secondary beams 49 Fe/ 49 V, respectively. The analogue properties of the reactions were used to help establish the new level scheme of 48 Fe. The inclusive and exclusive cross sections were determined for the populated states. Large differences between the cross sections for the two mirrored reactions were observed and have been interpreted in terms of different degrees of binding of the mirror nuclei and in the context of the recent observations of suppression of spectroscopic strength as a function of nuclear binding, for knockout reactions on light solid targets. Mirror energy differences (MED) have been determined between the analogue T = 2 states and compared with the shell model predictions. MED for this mirror pair, due to their location in the shell, are especially sensitive to excitations out of the f 7/2 shell, and present a stringent test of the shell-model prescription.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗