GRX-810 and the Future of AM-Enabled High-Temperature Propulsion
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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Cooperative and bifunctional materials (BFMs) that integrate adsorbents and catalysts offer a promising strategy for the reactive capture of CO 2 to produce valuable fuels and chemicals. In this study, we developed structured BFMs via 3D printing that combine CaO as an adsorbent with Ga–Ca–Cr 2 O 3 metal oxides as the catalyst for the reactive capture of CO 2 and its subsequent conversion to C 2 H 4 via the oxidative dehydrogenation of C 2 H 6 (CO 2 -ODHE). Three different Ga–Ca compositions were used to modify the catalyst surface characteristics and enhance C 2 H 4 selectivity. In these formulations, Ga ions stabilize the oxygen lattice of the BFM, while Ca ions interact strongly with Cr to form CaCrO 4 , thereby altering the oxygen species and enhancing the material’s basic properties. Under adsorption–reaction conditions at 600–650 °C, the optimal BFM achieved an excellent C 2 H 4 selectivity of 96.4 %, attributed to a balanced redox process and improved basicity that facilitate efficient C 2 H 6 conversion and rapid desorption of C 2 H 4 without excessive oxidation. Overall, this work provides new insights into the formulation of BFMs monoliths and highlights the critical role of catalytic surface modification in enhancing C 2 H 4 selectivity in the CO 2 -ODHE reactive capture process.
Although sea ice covers ~9% of the world’s oceans, its presence, and absence, vastly alter the energetic balance of Earth’s climate. Because of geographic differences, Arctic and Antarctic sea ice have different dominant properties and processes, which produce different responses to natural variability and anthropogenic change. In this Review, we survey changes in sea-ice properties and processes of the Arctic and Antarctic environments. In the Arctic, the melt season has lengthened by ~7.4 days decade −1 (1979-2024). There has been a corresponding decrease in winter sea-ice thickness (1.6 m mean total over 1980-2023), summer surface albedo (0.03 decade −1 over 1979-2020), and spring snow depth (2.5 cm decade −1 over 1954-2024). In comparison, corresponding changes in the Antarctic are small overall due to contrasting regional and temporal trends. From a dynamic perspective, sea-ice motion in both hemispheres has increased, with 0.63 cm s −1 decade −1 in the Arctic (1978-2024) and 0.69 cm s −1 decade −1 in the Antarctic (1982-2024), whereas trends in polynya occurrence differ by region. Future research should prioritize sea-ice observations that can inform how the climate system responds to natural variability and anthropogenic change, be standardized to increase uptake by the broader scientific community, and target process-oriented interactions to support model development.
The Latching End Effector (LEE) forms part of the Space Station Remote Manipulator System (SSRMS) for which Spar Aerospace Ltd, Space Systems Division is the prime contractor. The design, testing and performance evaluation of the Latching End Effector mechanisms is the subject of this paper focusing on: (1) ambient, thermal and vibration testing; (2) snare/rigidize performance testing and interaction during payload acquisition; and (3) latch/umbilical test results and performance.
The NASA Engineering and Safety Center (NESC) partnered with Materials and Processes and Flammability subject matter experts from the Johnson Space Center, White Sands Test Facility, and the Marshall Space Flight Center to design and develop a test for evaluating the effectiveness of material assemblies to serve as a barrier between a potential cabin ignition source based on typical flammable materials in the habitable volume of spacecraft.
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Topics considered include: Battery design, cell design, the 'VHS' type design, positive and negative electrodes, separator, electrolite, life test, performance test, accelerated cycle test.
The "International Ultraviolet Explorer (IUE) Battery History and Performance" report provides the information on the cell/battery design, battery performance during the thirty eight (38) solar eclipse seasons and the end-of-life test data. It is noteworthy that IUE spacecraft was an in-house project and that the batteries were designed, fabricated and tested (Qualification and Acceptance) at the Goddard Space Flight Center. A detailed information is given on the cell and battery design criteria and the designs, on the Qualification and the Acceptance tests, and on the cell life cycling tests. The environmental, thermal, and vibration tests were performed on the batteries at the battery level as well as with the interface on the spacecraft. The telemetry data were acquired, analyzed, and trended for various parameters over the mission life. Rigorous and diligent battery management programs were developed and implemented from time to time to extend the mission life over eighteen plus years. Prior to the termination of spacecraft operation, special tests were conducted to check the battery switching operation, battery residual capacity, third electrode performance and battery impedance.
With the advancement and adoption of Additive Manufacturing (AM) for spaceflight systems, numerous lessons have been learned during the qualification and certification of AM components. The lessons learned covered in this presentation will provide an overview of the challenges faced by NASA centers and commercial partners working to design AM hardware that complies with NASA-STD-6030 Additive Manufacturing Requirements (AMR). Topics of interest include tailoring of requirements for specific projects, documentation requirements, and addressing conservative approaches towards mechanical property development and analysis. In addition to that, this presentation aims to impress that these lessons learned will influence the future revisions of the NASA technical standard to facilitate and advance AM technology adoption on NASA projects.
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Introduction Bispecific antibodies (BsAbs) are a class of antibody therapeutics engineered in various molecular formats to bind two distinct antigens and potentially mediate multiple biological effects. These molecular formats are tailored to mediate specific mechanisms of action and possess unique physicochemical and biological properties that are necessary to assure product quality. In ovarian cancer (OC), both EGFR- and VEGF-A-mediated signaling pathways are often upregulated and cooperate to promote tumor growth and angiogenesis. Thus, inhibiting of EGFR- and VEGF-A pathways with a BsAb may provide synergistic anti-tumor activity. Methods Using publicly available sequences and applying immunoglobulin domain crossover (CrossMab) and knobs-into-holes (KIH) technologies, we generated a BsAb to simultaneously bind EGFR and VEGF-A (designated as anti-EGFR/VEGF-A BsAb). This BsAb served as a model for physiochemical and biological characterization of quality attributes that would be critical for the BsAb’s mechanisms of action. Our goal was to gain fundamental insights into BsAbs designed to target a receptor with one arm and a soluble ligand with the other, to support bioassay development and inform quality control strategies. Results Our data demonstrated that the CrossMab/KIH platform successfully produced a correctly assembled BsAb during cell culture. Characterization confirmed that the anti-EGFR/VEGF-A BsAb bound both EGFR and VEGF-A with comparable activity and affinity to the respective parental monoclonal antibodies. Functionally, the BsAb disrupted both EGF/EGFR and VEGF-A/VEGFR2 signaling pathways in OC and human umbilical vein endothelial cell (HUVEC) models. Furthermore, the BsAb effectively blocked angiogenic signaling driven by VEGF-A secreted from OC cells in a paracrine manner. Discussion Based on the combinatorial mechanism of action and our characterization findings, we concluded that two or more bioassays may be needed to accurately assess the activity of both arms of this type of BsAb.
Fabrication and test of polyethylene base material for heat sterilization resistance and for battery separators in silver-zinc alkaline cell
The following topics are presented in viewgraph format: Cosmic Background Explorer (COBE) mission background; battery background and specifications; cell history; battery mechanical/structural design; battery test data; and flowcharts of the various battery approval procedures.