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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 91 records · Page 5

Sequential Phenomena in Psychophysical Judgments: A Theoretical Analysis

This paper deals with an analysis of psychophysical detection experiments designed to assess the limit of a human observer's level of sensitivity. A mathematical theory or the detection process is introduced that, in contrast to previous theories, provides an analysis of the sequential effects observed in psychophysical data. Two variations of the detection task are considered: information feedback and no-information feedback. In the feedback situation the subject is given information concerning the correctness of his responses, whereas in the no-feedback situation he is not. Data from a visual detection experiment with no-information feedback, and from an auditory detection experiment with information feedback are analyzed in terms of the theory. Finally, some general results are derived concerning the relationship between performance in the feedback situation and the no-feedback situation.

Atkinson, R. C.↗

Software approach to automatic patching of analog computer

The Automatic Patching Verification program (APV) is described which provides the hybrid computer programmer with a convenient method of performing a static check of the analog portion of his study. The static check insures that the program is patched as specified, and that the computing components being used are operating correctly. The APV language the programmer uses to specify his conditions and interconnections is similar to the FORTRAN language in syntax. The APV control program reads APV source program statements from an assigned input device. Each source program statement is processed immediately after it is read. A statement may select an analog console, set an analog mode, set a potentiometer or DAC, or read from the analog console and perform a test. Statements are read and processed sequentially. If an error condition is detected, an output occurs on an assigned output device. When an end statement is read, the test is terminated.

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Applying Multimodal Mass Spectrometry to Image Tumors Undergoing Ferroptosis Following In Vivo Treatment with a Ferroptosis Inducer

Epithelial ovarian cancer (EOC) is the most common form of ovarian cancer. The poor prognosis generally associated with this disease has led to the search for improved therapies such as ferroptosis-inducing agents. Ferroptosis is a form of regulated cell death that is dependent on iron and is characterized by lipid peroxidation. Precise mapping of lipids and iron within tumors exposed to ferroptosis-inducing agents may provide insight into processes of ferroptosis in vivo and ultimately assist in the optimal deployment of ferroptosis inducers in cancer therapy. In this work, we present a method for combining matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) with secondary ion mass spectrometry (SIMS) to analyze changes in spatial lipidomics and metal composition, respectively, in ovarian tumors following exposure to a ferroptosis inducer. Tumors were obtained by injecting human ovarian cancer tumor-initiating cells into mice, followed by treatment with the ferroptosis inducer erastin. SIMS imaging detected iron accumulation in the tumor tissue, and sequential MALDI-MS imaging of the same tissue section displayed two chemically distinct regions of lipids. Additionally, one region was associated with the iron-rich area detected with SIMS, and the other region encompassed the remainder of the tissue section. Bulk lipidomics confirmed the lipid assignments putatively assigned from the MALDI-MS data. Overall, we demonstrate the ability of multimodal MSI to identify the spatial locations of iron and lipids in the same tissue section and associate these regions with clinical pathology.

60 APPLIED LIFE SCIENCES↗

Detection of feed-through faults in CMOS storage elements

In testing sequential circuits, internal faults in the storage elements (SE's) are sometimes modeled as stuck-at faults in the combinational circuits surrounding the SE. The detection of some transistor-level faults that cannot be modeled as stuck-at are considered. These feed-through faults cause the cell to become either data-feed-through, which makes the cell combinational, or clock-feed-through, which causes the clock signal or its complement to appear at the output. Under such faults, the cell does not function as a memory element. Here it is shown that such faults may or may not be detected depending on delays involved. Conditions under which race-ahead occurs are identified.

Al-Assadi, Waleed K.↗

An adaptive technique for a redundant-sensor navigation system.

An on-line adaptive technique is developed to provide a self-contained redundant-sensor navigation system with a capability to utilize its full potentiality in reliability and performance. This adaptive system is structured as a multistage stochastic process of detection, identification, and compensation. It is shown that the detection system can be effectively constructed on the basis of a design value, specified by mission requirements, of the unknown parameter in the actual system, and of a degradation mode in the form of a constant bias jump. A suboptimal detection system on the basis of Wald's sequential analysis is developed using the concept of information value and information feedback. The developed system is easily implemented, and demonstrates a performance remarkably close to that of the optimal nonlinear detection system. An invariant transformation is derived to eliminate the effect of nuisance parameters such that the ambiguous identification system can be reduced to a set of disjoint simple hypotheses tests. By application of a technique of decoupled bias estimation in the compensation system the adaptive system can be operated without any complicated reorganization.

Chien, T.-T.↗

Detection, mapping and estimation of rate of spread of grass fires from southern African ERTS-1 imagery

Sequential band-6 imagery of the Zambesi Basin of southern Africa recorded substantial changes in burn patterns resulting from late dry season grass fires. One example from northern Botswana, indicates that a fire consumed approximately 70 square miles of grassland over a 24-hour period. Another example from western Zambia indicates increased fire activity over a 19-day period. Other examples clearly define the area of widespread grass fires in Angola, Botswana, Rhodesia and Zambia. From the fire patterns visible on the sequential portions of the imagery, and the time intervals involved, the rates of spread of the fires are estimated and compared with estimates derived from experimental burning plots in Zambia and Canada. It is concluded that sequential ERTS-1 imagery, of the quality studied, clearly provides the information needed to detect and map grass fires and to monitor their rates of spread in this region during the late dry season.

Wightman, J. M.↗

Pattern-aware prefetching using parallel log-structured file system

Techniques are provided for pattern-aware prefetching using a parallel log-structured file system. At least a portion of one or more files is accessed by detecting at least one pattern in a non-sequential access of the one or more files; and obtaining at least a portion of the one or more files based on the detected at least one pattern. The obtaining step comprises, for example, a prefetching or pre-allocation of the at least the portion of the one or more files. A prefetch cache can store the portion of the one or more obtained files. The cached portion of the one or more files can be provided from the prefetch cache to an application requesting the at least a portion of the one or more files.

Bent, John M.↗

Simplified command and range detection system

Communication system processes subcarrier that is modulated with sequential range codes and with command data. Loop locks in on range codes as they occur in sequence. When range code modulated with data-frequency arrives, loop switches to DEMOD to receive data.

Butman, S. A.↗

Integrated Miniature Arrays of Optical Biomolecule Detectors

Integrated miniature planar arrays of optical sensors for detecting specific biochemicals in extremely small quantities have been proposed. An array of this type would have an area of about 1 cm2. Each element of the array would include an optical microresonator that would have a high value of the resonance quality factor (Q . 107). The surface of each microresonator would be derivatized to make it bind molecules of a species of interest, and such binding would introduce a measurable change in the optical properties of the microresonator. Because each microresonator could be derivatized for detection of a specific biochemical different from those of the other microresonators, it would be possible to detect multiple specific biochemicals by simultaneous or sequential interrogation of all the elements in the array. Moreover, the derivatization would make it unnecessary to prepare samples by chemical tagging. Such interrogation would be effected by means of a grid of row and column polymer-based optical waveguides that would be integral parts of a chip on which the array would be fabricated. The row and column polymer-based optical waveguides would intersect at the elements of the array (see figure). At each intersection, the row and column waveguides would be optically coupled to one of the microresonators. The polymer-based waveguides would be connected via optical fibers to external light sources and photodetectors. One set of waveguides and fibers (e.g., the row waveguides and fibers) would couple light from the sources to the resonators; the other set of waveguides and fibers (e.g., the column waveguides and fibers) would couple light from the microresonators to the photodetectors. Each microresonator could be addressed individually by row and column for measurement of its optical transmission. Optionally, the chip could be fabricated so that each microresonator would lie inside a microwell, into which a microscopic liquid sample could be dispensed.

Iltchenko, Vladimir↗

Sequentially calibrating a Bayesian microsimulation model to incorporate new information and assumptions

Background: Microsimulation models are mathematical models that simulate event histories for individual members of a population. They are useful for policy decisions because they simulate a large number of individuals from an idealized population, with features that change over time, and the resulting event histories can be summarized to describe key population-level outcomes. Model calibration is the process of incorporating evidence into the model. Calibrated models can be used to make predictions about population trends in disease outcomes and effectiveness of interventions, but calibration can be challenging and computationally expensive. Methods: This paper develops a technique for sequentially updating models to take full advantage of earlier calibration results, to ultimately speed up the calibration process. A Bayesian approach to calibration is used because it combines different sources of evidence and enables uncertainty quantification which is appealing for decision-making. We develop this method in order to re-calibrate a microsimulation model for the natural history of colorectal cancer to include new targets that better inform the time from initiation of preclinical cancer to presentation with clinical cancer (sojourn time), because model exploration and validation revealed that more information was needed on sojourn time, and that the predicted percentage of patients with cancers detected via colonoscopy screening was too low. Results: The sequential approach to calibration was more efficient than recalibrating the model from scratch. Incorporating new information on the percentage of patients with cancers detected upon screening changed the estimated sojourn time parameters significantly, increasing the estimated mean sojourn time for cancers in the colon and rectum, providing results with more validity. Conclusions: A sequential approach to recalibration can be used to efficiently recalibrate a microsimulation model when new information becomes available that requires the original targets to be supplemented with additional targets.

60 APPLIED LIFE SCIENCES↗

Performance of a finite phase state bit-synchronization loop with and without sequential filters

A discrete phase state bit-synchronization loop is proposed for synchronization and detection of a binary nonreturn-to-zero (NRZ) process. The general loop model is developed for 11 and 17 phase states with optional sequential loop filter. Loop performance is considered in terms of the phase error density function, rms phase error, and mean time to bit slippage. It is shown that satisfactory loop performance can be achieved at -3 dB SNR through use of sequential loop filters.

Ransom, J. J.↗

Automated Microbial Metabolism Laboratory

The Automated Microbial Metabolism Laboratory (AMML) 1971-1972 program involved the investigation of three separate life detection schemes. The first was a continued further development of the labeled release experiment. The possibility of chamber reuse without inbetween sterilization, to provide comparative biochemical information was tested. Findings show that individual substrates or concentrations of antimetabolites may be sequentially added to a single test chamber. The second detection system which was investigated for possible inclusion in the AMML package of assays, was nitrogen fixation as detected by acetylene reduction. Thirdly, a series of preliminary steps were taken to investigate the feasibility of detecting biopolymers in soil. A strategy for the safe return to Earth of a Mars sample prior to manned landings on Mars is outlined. The program assumes that the probability of indigenous life on Mars is unity and then broadly presents the procedures for acquisition and analysis of the Mars sample in a manner to satisfy the scientific community and the public that adequate safeguards are being taken.

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Multiple-laser-energy detection system

Technique monitors energy output of each of four sequentially-pulsed dye lasers for the Airborne LIDAR Oceanographic Probing Experiment system. Fiber optics attached to output mirrors transmit optical signal proportional to output energy.

Jarrett, O., Jr.↗

Computer simulation of a space SAR using a range-sequential processor for soil moisture mapping

The ability of a spaceborne synthetic aperture radar (SAR) to detect soil moisture was evaluated by means of a computer simulation technique. The computer simulation package includes coherent processing of the SAR data using a range-sequential processor, which can be set up through hardware implementations, thereby reducing the amount of telemetry involved. With such a processing approach, it is possible to monitor the earth's surface on a continuous basis, since data storage requirements can be easily met through the use of currently available technology. The Development of the simulation package is described, followed by an examination of the application of the technique to actual environments. The results indicate that in estimating soil moisture content with a four-look processor, the difference between the assumed and estimated values of soil moisture is within + or - 20% of field capacity for 62% of the pixels for agricultural terrain and for 53% of the pixels for hilly terrain. The estimation accuracy for soil moisture may be improved by reducing the effect of fading through non-coherent averaging.

Fujita, M.↗

End-To-End Decentralized Transmission Line Protection in IBR-Dominated Weak Grids Using Interpretable Data-Driven Methods

Traditional transmission line protection relies on predictable synchronous-based fault signatures, which frequently fail under the non-standard, current-limited fault characteristics of Inverter-Based Resources (IBRs). This study investigates how to achieve secure, communication-free fault isolation in IBR-dominated weak grids without relying on opaque, computationally heavy "black-box" machine learning algorithms. To address this, we propose a novel, standalone, and inherently interpretable data-driven protection framework. Unlike centralized methods requiring multi-terminal communication, this decentralized approach relies solely on local measurements using a hierarchical linear-kernel Support Vector Machine (SVM). The methodology decomposes the protection task into four sequential stages that mimic traditional protection elements: fault detection and fault direction identification, fault type classification, zone classification, and location estimation. This multi-stage architecture allows for specialized feature engineering at each stage, combining high computational efficiency with logic traceability. The framework's end-to-end performance was validated via C-code and PSCAD/EMTDC co-simulation, utilizing a real-world utility network and an OEM black-box IBR model. The proposed relay achieves 97.2% overall accuracy and provides a reliable trip decision within a 2.5-cycle window. The results confirm 100% accuracy in fundamental fault detection, reliable zone selectivity across low to moderate fault resistances, and robust security against non-fault transients, proving its immediate viability for integration into commercial numerical relays.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Sequential control chart methodology

A modification of the V mask sequential control chart is proposed. In this modified scheme, a parabolic section is included in the mask to provide better performance when the process undergoes a large change in the mean from goal conditions. It is shown that the modified V mask can be implemented either in conventional graphic form, or in an algorithmic form suitable for a digital computer. Average run lengths are given for a typical range of circumstances. It also is shown that the conventional Shewhart chart is better than a sequential chart for the specific purpose of promptly detecting very large shifts of the mean from goal conditions.

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Behavior of faulty double BJT BiCMOS logic gates

Logic Behavior of a Double BJT BiCMOS device under transistor level shorts and opens is examined. In addition to delay faults, faults that cause the gate to exhibit sequential behavior were observed. Several faults can be detected only by monitoring the current. The faulty behavior of Bipolar (TTL) and CMOS logic families is compared with BiCMOS, to bring out the testability differences.

Menon, Sankaran M.↗