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Why Should Humans Explore a Near Earth Asteroid and What Factors Drive the Medical Risks?

The National Aeronautics and Space Administration (NASA) is currently considering plans for the human exploration of a Near Earth Asteroid (NEA). Reasons for undertaking the human exploration of a NEA include increasing the scientific understanding of the origins of our solar system, and developing technology for the exploration of more distant destinations such as Mars. Most mission scenarios have a duration on the order of several months or a year, most of which is spent in transit to and from the NEA. The choice of a particular NEA destination determines the mission duration and guides the types of exploration activities that can be performed on and near the NEA. NASA s Human Research Program (HRP) has identified short and long-term health risks associated with such missions and begun characterizing the level of risk. Some risk drivers are well known from missions to low Earth orbit and the Moon (e.g., the limited mass, volume, and power available for the medical care system). Other factors emerge as major drivers for NEA missions. Some are fundamental characteristics of the mission parameters (e.g., mission duration, distance) and others are strongly dependent on the specifics of how the mission is implemented (e.g., isolation and confinement). Careful consideration of these factors will be required for safe and effective missions to NEAs.

Kundrot, Craig E.↗

Rapid Biochemical Analysis on the International Space Station (ISS): Preparing for Human Exploration of the Moon and Mars

The Lab-on-a-Chip Application Development - Portable Test System, known as LOCAD-PTS, was launched to the International Space Station (ISS) aboard Space Shuttle Discovery (STS-116) on December 9th,2006. Since that time, it has remained onboard ISS and has been operated by the crew on 10 separate occasions LOCAD-PTS is a handheld device for rapid biochemical analysis; it consists of a spectrophotometer, a series of interchangeable cartridges, a pipette and several clean/sterilized swabbing kits to obtain samples from ISS surfaces. Sampling, quantitative analysis and data retrieval is performed onboard, therefore reducing the need to return samples to Earth. Less than 20 minutes are required from sampling to data, significantly faster than existing culture-based methods on ISS, which require 3-5 days. Different cartridges are available for the detection of different target molecules (simply by changing the formulation within each cartridge), thereby maximizing the benefit and applications addressed by a single instrument. Initial tests on ISS have focused on the detection of the bact.erial macromolecule endotoxin, a component of bacterial cell walls. LOCAD-PTS detects endotoxin with a cartridge that contains a formulation known as Limulus Amebocyte Lysate (LAL) assay. LAL is derived from blood of the horseshoe crab, Limulus polyphemus, and detects enodotoxin with an enzyme cascade that triggers generation Of a yellow colored dye, p-nitroanaline. The more p-nitroanaline product, the more endotoxin is in the original sample. To enable quantitative analysis, the absorbance of this color is measured by LOCAD-PTS through a 395 nm filter and compared with an internal calibration curve, to provide a reading on the LED display that ranges from 0.05 Endotoxin Units (EU)/ml to 5 EU/ml. Several surface sites were analyzed within ISS between March 2007 and February 2008, including multiple locations in the US Laboratory Destiny, Node 1 Unity, AMock, and Service Module Zvezda. The goals of this initial study were to i) test the cleanliness of reagents/supplies on orbit, ii) test the crew's ability to collect and process a sample in microgravity without contamination, iii) demonstrate nominal function of the LOCAD-PTS, and iv) provide a general survey of endotoxin within the ISS. The surface sites varied greatly in terms of their frequency-of-use and material texture/composition; from relatively smooth aluminum, to fabric, to the room temperature vulcanizing (RTV) rubber of a Extravehicular Mobility Unit (EMU) spacesuit. Results showed that: i) the swabbing kits and reagents remained clean on orbit, ii) the crew could collect and process a sample without contamination, and iii) the LOCAD-PTS functioned nominally in > 99% of the 55 tests completed. We will present detailed results of the survey of endotoxin on ISS surfaces. These results and technology are important in the near-term - by providing an extra tool in the toolbox for ISS microbial monitoring. They are also important in the longer term as valuable preparation for human exploration of the Moon and Mars. One of the proposed science goals for the human exploration of Mars will be to detect and characterize any indigenous biological molecules that may exist on the Martian surface. To achieve that goal, the crew must have the technology available onboard to differentiate indigenous biology from any terrestrial biological material brought to Mars by the spacecraft and crew (termed 'forward contamination'). The LAL assay is already one of the official methods used by NASA's planetary protection program to certify cleanliness of interplanetary robotic spacecraft prior to launch; and therefore endotoxin is a good marker of forward contamination (as well as other microbial molecules detectable with LOCAD-PTS e.g. box-1, 3-glucan and lipoteichoic acid). Furthermore, the distribution and abundance of these molecules on the ISS provides a good indicator of what to expect on the Crew Exploratioehicle Orion, the lunar lander Antares, and future crewed spacecraft destined for Mars. In addition, technology such as LOCAD-PTS has been proposed to help evaluate forward contamination during lunar surface operations by the crew, as preparation for the human exploration of Mars.

Maule, J.↗

The Search for Extant Life on Mars: A Human Exploration Objective

A search for evidence of extant life on Mars should be conducted prior to and as part of human exploration missions. Potentially habitable environments for modern life occur on Mars. Despite a vigorous campaign of exploration of the surface over the last 3 decades, no mission has attempted to search for signatures of extant life since the Viking landers in 1976. Finding an example of extant life beyond Earth would be one of the greatest scientific discoveries of all time. This is especially important because (once discovered) the biochemistry and metabolism of the life form can be studied. Earth and Mars exchange materials over geologic time because impacts eject rock and crustal materials into space that are eventually deposited on other planets and moons [1]. Therefore, Earth and Mars could share life with a common origin and similar biochemistry; if this is the case, life on Mars likely experienced billions of years of evolution in isolation from Earth. Alternatively, Mars may host a distinct genesis of life which could be evident from its different biochemistry. Either discovery would change our understanding of life in the solar system and beyond. The Mars 2020/Perseverance sample collection mission is not optimized for finding extant life because the site for sample collection, Jezero Crater, was chosen for its ancient habitability and likelihood to host fossil evidence of life. Furthermore, the samples collected will not be returned for at least a decade. Within that period, technology development for human exploration will likely be underway and it is possible that humans will land on Mars without an updated knowledge of extant life on Mars, which may pose a risk both to those mission crews and to Earth when they return. Thus, it is important to perform a search for extant life on Mars prior to humans landing at a site where life may persist. Salts and shallow ground ice are particularly important environments to evaluate for extant life prior to human missions because they may be encountered and interacted with by human crews.

C.R. Stoker↗

Human Exploration of Mars Design Reference Architecture 5.0

This document reviews the Design Reference Architecture (DRA) for human exploration of Mars. The DRA represents the current best strategy for human missions. The DRA is not a formal plan, but provides a vision and context to tie current systems and technology developments to potential missions to Mars, and it also serves as a benchmark against which alternative architectures can be measured. The document also reviews the objectives and products of the 2007 study that was to update NASA's human Mars mission reference architecture, assess strategic linkages between lunar and Mars strategies, develop an understanding of methods for reducing cost/risk of human missions through investment in research, technology development and synergy with other exploration plans. There is also a review of the process by which the DRA will continue to be refined. The unique capacities of human exploration is reviewed. The possible goals and objectives of the first three human missions are presented, along with the recommendation that the mission involve a long stay visiting multiple sites.The deployment strategy is outlined and diagrammed including the pre-deployment of the many of the material requirements, and a six crew travel to Mars on a six month trajectory. The predeployment and the Orion crew vehicle are shown. The ground operations requirements are also explained. Also the use of resources found on the surface of Mars is postulated. The Mars surface exploration strategy is reviewed, including the planetary protection processes that are planned. Finally a listing of the key decisions and tenets is posed.

Drake, Bret G.↗

A Systems Study to Determine the Attractiveness of Solar System Bodies and Sites for Eventual Human Exploration

A pre-phase A idea-generation team at the Jet Propulsion Laboratory (JPL), has conducted a study to rank all locations in the solar system based on attractiveness for human exploration. The process used to perform the study was composed of the following primary steps: determination of criteria (including value, cost, and risk criteria) upon which to rate sites in the solar system; weighting of the criteria based upon importance to eventual human exploration; selection of sites to consider and assignment of team members to the task of advocating the benefits of particular sites; rating the sites in both the short- and longterm based on team member presentations and team discussions; compilation of a score based on criteria weights and individual ratings. Finally a comparison of the total scores of different sites was completed to determine a ranking of all the bodies and sites in the solar system. Sensitivity analysis was also performed to determine how weightings affect the rankings.

human exploration↗

Human Exploration of Near-Earth Asteroids

A major goal for NASA's human spaceflight program is to send astronauts to near-Earth asteroids (NEA) in the coming decades. Missions to NEAs would undoubtedly provide a great deal of technical and engineering data on spacecraft operations for future human space exploration while conducting in-depth scientific examinations of these primitive objects. However, before sending human explorers to NEAs, robotic investigations of these bodies would be required to maximize operational efficiency and reduce mission risk. These precursor missions to NEAs would fill crucial strategic knowledge gaps concerning their physical characteristics that are relevant for human exploration of these relatively unknown destinations. Dr. Paul Abell discussed some of the physical characteristics of NEOs that will be relevant for EVA considerations, reviewed the current data from previous NEA missions (e.g., Near-Earth Asteroid Rendezvous (NEAR) Shoemaker and Hayabusa), and discussed why future robotic and human missions to NEAs are important from space exploration and planetary defense perspectives.

Abell, Paul↗

Human Exploration of Near-Earth Asteroids

A major goal for NASA's human spaceflight program is to send astronauts to near-Earth asteroids (NEA) in the coming decades. Missions to NEAs would undoubtedly provide a great deal of technical and engineering data on spacecraft operations for future human space exploration while conducting in-depth scientific examinations of these primitive objects. However, before sending human explorers to NEAs, robotic investigations of these bodies would be required to maximize operational efficiency and reduce mission risk. These precursor missions to NEAs would fill crucial strategic knowledge gaps concerning their physical characteristics that are relevant for human exploration of these relatively unknown destinations. Dr. Paul Abell discussed some of the physical characteristics of NEOs that will be relevant for EVA considerations, reviewed the current data from previous NEA missions (e.g., Near-Earth Asteroid Rendezvous (NEAR) Shoemaker and Hayabusa), and discussed why future robotic and human missions to NEAs are important from space exploration and planetary defense perspectives.

Abell, Paul↗

NASA's Asteroid Redirect Mission: A Robotic Boulder Capture Option for Science, Human Exploration, Resource Utilization, and Planetary Defense

NASA is examining two options for the Asteroid Redirect Mission (ARM), which will return asteroid material to a Lunar Distant Retrograde Orbit (LDRO) using a robotic solar electric propulsion spacecraft, called the Asteroid Redirect Vehicle (ARV). Once the ARV places the asteroid material into the LDRO, a piloted mission will rendezvous and dock with the ARV. After docking, astronauts will conduct two extravehicular activities (EVAs) to inspect and sample the asteroid material before returning to Earth. One option involves capturing an entire small (~4 - 10 m diameter) near-Earth asteroid (NEA) inside a large inflatable bag. However, NASA is also examining another option that entails retrieving a boulder (~1 - 5 m) via robotic manipulators from the surface of a larger (~100+ m) pre-characterized NEA. The Robotic Boulder Capture (RBC) option can leverage robotic mission data to help ensure success by targeting previously (or soon to be) well- characterized NEAs. For example, the data from the Japan Aerospace Exploration Agency's (JAXA) Hayabusa mission has been utilized to develop detailed mission designs that assess options and risks associated with proximity and surface operations. Hayabusa's target NEA, Itokawa, has been identified as a valid target and is known to possess hundreds of appropriately sized boulders on its surface. Further robotic characterization of additional NEAs (e.g., Bennu and 1999 JU3) by NASA's OSIRIS REx and JAXA's Hayabusa 2 missions is planned to begin in 2018. This ARM option reduces mission risk and provides increased benefits for science, human exploration, resource utilization, and planetary defense. Science: The RBC option is an extremely large sample-return mission with the prospect of bringing back many tons of well-characterized asteroid material to the Earth-Moon system. The candidate boulder from the target NEA can be selected based on inputs from the world-wide science community, ensuring that the most scientifically interesting boulder be returned for subsequent sampling. In addition, the material surrounding the boulder can be collected from the surface, thus providing geological contextual information and additional samples of NEA regolith. The robotic manipulators used for capturing the boulder will ensure some of the surface remains undisturbed and that the boulder will retain its structural integrity, which will preserve the context of any samples collected by the astronauts and ensure a high level of science return. Human Exploration: Due to the coherent nature of the boulder that will be collected, entire encapsulation of the asteroid material is not required. This facilitates exploration and sample collection of the boulder by astronauts in a variety of ways. The total time for EVA during the crew portion of the mission is very limited. Current estimates are that each of the two EVAs will only last four hours. The RBC option will allow crew members to have good situational awareness of the work site and quickly identify sample sites of interest. In addition, the samples to be collected can be readily accessed without having to deal with removal of an encapsulation system, which adds extra complexity and risk for the astronauts during EVA. Resource Utilization: One of the most crucial aspects for resource utilization is the identification and collection of appropriate materials (e.g., volatiles, organics, metals, etc.) that contain components of interest. Prior characterization of NEAs is required in order to increase the likelihood that appropriate materials will be returned. Ground-based observations of small (<10 m) NEAs are challenging, but characterization efforts of larger targets have demonstrated that NEAs with volatiles and organics have been identified. Two potential targets for the RBC option (Bennu and 1999 JU3) have been previously identified as potentially rich in resources, and both are already targets of currently planned robotic missions that will characterize their physical properties in great detail. Planetary Defense: The RBC option involves interaction with a well- characterized potentially hazardoussized NEA that would enable NASA to conduct one or more planetary defense demonstrations. The primary method would use the collected boulder to augment the mass of the ARV and perform an Enhanced Gravity Tractor (EGT) demonstration on the NEA. Additionally, other approaches could be demonstrated during the mission, such as Ion Beam Deflection (IBD) and/or observation of a Kinetic Impactor (KI). The relative effectiveness of a slow push-pull method such as the EGT or IBD could be directly compared and contrasted with the results of the more energetic KI method on the target NEA. Conclusions: This boulder option for NASA's ARM can leverage knowledge of previously characterized NEAs from prior robotic missions, which provides more certainty of the target NEA's physical characteristics and reduces mission risk. This increases the return on investment for NASA's future activities with respect to human exploration, resource utilization, and planetary defense.

Abell, P.↗

Planetary Protection Issues in the Human Exploration of Mars

This workshop report, long delayed, is the first 21st century contribution to what will likely be a series of reports examining the effects of human exploration on the overall scientific study of Mars. The considerations of human-associated microbial contamination were last studied in a 1990 workshop ("Planetary Protection Issues and Future Mars Missions," NASA CP-10086, 1991), but the timing of that workshop allowed neither a careful examination of the full range of issues, nor an appreciation for the Mars that has been revealed by the Mars Global Surveyor and Mars Pathfinder missions. Future workshops will also have the advantage of Mars Odyssey, the Mars Exploration Rover missions, and ESA's Mars Express, but the Pingree Park workshop reported here had both the NCR's (1992) concern that "Missions carrying humans to Mars will contaminate the planet" and over a decade of careful study of human exploration objectives to guide them and to reconcile. A daunting challenge, and one that is not going to be simple (as the working title of this meeting, "When Ecologies Collide?" might suggest), it is clear that the planetary protection issues will have to be addressed to enable human explorers to safely and competently extend out knowledge about Mars, and its potential as a home for life whether martian or human.

Criswell, Marvin E.↗

Results of the Lunar Exploration Analysis Group (LEAG) Gap Review: Specific Action Team (SAT), Examination of Strategic Knowledge Gaps (SKGs) for Human Exploration of the Moon

The Lunar Exploration Analysis Group (LEAG) was tasked by the Human Exploration Operations Mission Directorate (HEOMD) to establish a Specific Action Team (SAT) to review lunar Strategic Knowledge Gaps (SKGs) within the context of new lunar data and some specific human mission scenarios. Within this review, the SAT was to identify the SKGs that have been fully or partially retired, identify new SKGs resulting from new data and observations, and review quantitative descriptions of measurements that are required to fill knowledge gaps, the fidelity of the measurements needed, and if relevant, provide examples of existing instruments or potential missions capable of filling the SKGs.

Shearer, C. K.↗

Telerobotics for Human Exploration: Enhancing Crew Capabilities in Deep Space

Future space missions in Earth orbit, to the Moon, and to other distant destinations offer many new opportunities for exploration. But, astronaut time will always be limited and some work will not be feasible or efficient for humans to perform manually. Telerobots, however, can complement human explorers, performing work under remote control from Earth, orbit or nearby habitats. A central challenge, therefore, is to understand how humans and remotely operated robots can be jointly employed to maximize mission performance and success. This presentation provides an overview of the key issues with using telerobots for human exploration.

telerobotics↗

Human Exploration of Mars Design Reference Architecture 5.0, Addendum #2

This report serves as the second Addendum to NASA-SP-2009-566, "Human Exploration of Mars Design Reference Architecture 5.0." The data and descriptions contained within this Addendum capture some of the key assessments and studies produced since publication of the original document, predominately covering those conducted from 2009 through 2012. The assessments and studies described herein are for the most part independent stand-alone contributions. Effort has not been made to assimilate the findings to provide an updated integrated strategy. That is a recognized future effort. This report should not be viewed as constituting a formal plan for the human exploration of Mars.

Drake, Bret G.↗

Transition in the Human Exploration of Space at NASA

NASA is taking the next step in human exploration, beyond low Earth orbit. We have been going to low Earth orbit for the past 50 years and are using this experience to work with commercial companies to perform this function. This will free NASA resources to develop the systems necessary to travel to a Near Earth Asteroid, the Moon, Lagrange Points, and eventually Mars. At KSC, we are positioning ourselves to become a multi-user launch complex and everything we are working on is bringing us closer to achieving this goal. A vibrant multi-use spaceport is to the 21st Century what the airport was to the 20th Century - an invaluable transportation hub that supports government needs while promoting economic development and commercial markets beyond Earth's atmosphere. This past year saw the end of Shuttle, but the announcements of NASA's crew module, Orion, and heavy-lift rocket, the SLS, as well as the establishment of the Commercial Crew Program. We have a busy, but very bright future ahead of us and KSC is looking forward to playing an integral part in the next era of human space exploration. The future is SLS, 21st Century Ground Systems Program, and the Commercial Crew Program; and the future is here.

Koch, Carla A.↗

Human exploration of space: A review of NASA's 90-day study and alternatives

The National Research Council (NRC) examines the NASA Report of the 90-Day Study on Human Exploration of the Moon and Mars, and alternative concepts. Included in this paper, prepared for the National Space Council, are the answers to a challenging set of questions posed by the Vice President. Concerns addressed include: the appropriate pace, the scope of human exploration, the level of long-term support required, the technology development available and needed, the feasibility of long-duration human spaceflight in a low-gravity environment, scientific objectives, and other considerations such as costs and risks.

Stever, H. Guyford↗

Destination Deimos: A Design Reference Architecture for Initial Human Exploration of the Mars System

The two biggest challenges to successful human operations in interplanetary space are flight dynamics, constrained by the cold hard physics of the rocket equation, and bioastronautics, the psychophysiological realities of human adaptation, or lack thereof, to the deep space environment. Without substantial innovation in project/mission architecture and vehicle design, human exploration of the Mars system could be problematic for decades. Although a human landing on Mars is inevitable, humans-in-the-loop telerobotic exploration from the outer Martian moon Deimos is the best way to begin. Precursor robotic missions for reconnaissance and local site preparation will be required.

Logan, James S.↗

Gateway Program Safety and Mission Assurance Integration - The Future of Safe Deep Space Human Exploration

As a foundational element of the National Aeronautics and Space Administration (NASA) Artemis Campaign, the Gateway is an incrementally built cislunar spacecraft that will serve as a platform for deep space human exploration, science, and technology demonstration. The Gateway will be a unifying catalyst for partners around the world to establish sustained deep space scientific investigations, lunar surface access, and missions to Mars. As human exploration moves farther from Earth, spacecraft designs must optimize mass and volume while minimizing human and spacecraft risk. To accomplish this, the Gateway Program Safety and Mission Assurance (S&MA) office develops, implements, and ensures compliance with requirements, in concert with the accurate characterization and transparent communication of residual hazard risks, for integrated safety, reliability and maintainability, and quality assurance. This paper will detail the evolution of the Gateway Program S&MA integration functions, and provide its current status and lessons learned for future human spaceflight programs.

Helen Vaccaro↗

Gateway Program Safety and Mission Assurance Integration - the Future of Safe Deep Space Human Exploration

As a foundational element of the National Aeronautics and Space Administration (NASA) Artemis Campaign, the Gateway is an incrementally built cislunar spacecraft that will serve as a platform for deep space human exploration, science, and technology demonstration. The Gateway will be a unifying catalyst for international partners around the world to establish sustained deep space scientific investigations, lunar surface access, and missions to Mars. As human exploration moves farther away from Earth, spacecraft designs must prioritize and optimize mass and volume allocations, while minimizing human and spacecraft risk. To accomplish this objective, the Gateway Program Safety and Mission Assurance functions develop, implement, and ensure compliance with requirements, in concert with the accurate characterization and transparent communication of residual hazard risks, for integrated safety, reliability and maintainability and quality assurance. Safety and Mission Assurance was a key contributor during Gateway program pre-formulation and formulation activities where safety and reliability analysis was embedded in the Gateway Systems Engineering and Integration team. During these early program stages, a preliminary Gateway Integrated Hazard Analysis and Preliminary Gateway Probabilistic Risk Assessment assisted in Gateway architectural and operational definition as part of a risk-informed design process. As the deep space architecture has matured, the integrated Safety and Mission Assurance analyses have matured, new safety review processes have been developed, and requirements have been refined to ensure compliance with integrated safety and mission assurance objectives. The Gateway Program is currently concluding the preliminary design review informed milestone, where the primary objectives included: - Ensured completeness and consistency of the preliminary design, including the meeting of all requirements within appropriate margins and acceptable risk posture. - Identification of any major issues moving forward to the Critical Design phase. At this milestone, Safety and Mission Assurance provided numerous products, including Gateway Top Risks and Risk Mitigation Plans, updated integrated hazard analyses, updated probabilistic risk assessment, Crew Survival Analysis Report, and updated Safety and Mission Assurance Requirements and Plans. These products provide a many-faceted perspective on the inherent risk and available mitigations involved in flying the current proposed vehicle design and anticipated stack configurations. In addition, Safety and Mission Assurance identified top technical, process and workforce concerns to be addressed as the program progresses toward the critical design phase. This paper will detail the evolution of the Gateway Program Safety and Mission Assurance integration functions, provide its current status and lessons learned for future human spaceflight programs. Throughout this paper the key tenets of the Gateway Program Safety and Mission Assurance will be discussed: - Application of a risk-informed approach to identify and mitigate areas of highest risk. - Leverage of valuable processes and lessons learned from earlier spaceflight programs. - Development of Safety and Mission Assurance products to inform design risk trades. - Utilization of common Safety and Mission Assurance practices to identify safety risks for multiple perspectives: top-down, bottom-up, and across lines of integration. - Approval of safety hazards at the appropriate level of authority, keeping most deliberation closest to design expertise and elevating risks of greatest concern for program-level consideration. - Championing of Safety and Mission Assurance processes and forums to foster a pervasive safety culture that is transparent, inclusive, and collaborative between all partners. These tenets have allowed the Gateway Safety and Mission Assurance function to play a key role in optimized vehicle design evolution, and early identification and mitigation of Gateway program and Artemis mission risk.

Helen Vaccaro↗