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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,207 records · Page 67

MO-G-BRF-06: Radiotherapy and Prompt Oxygen Dynamics

Purpose: Adaptive radiotherapy requires a knowledge of the changing local tumor oxygen concentrations for times on the order of the treatment time, a time scale far shorter than cell death and proliferation. This knowledge will be needed to guide hypofractionated radiotherapy. Methods: A diffuse optical probe system was developed to spatially average over the whole interior of athymic Sprague Dawley nude mouse xenografts of human head and neck cancers. The blood volume and hemoglobin saturation was measured in real time. The quantities were measured with spectral fitting before and after 10 Gy of radiation is applied. An MRI BOLD scan is acquired before and after 10 Gy that measures regional changes in R2* which is inversely proportional to oxygen availability. Simulations were performed to fit the blood oxygen dynamics and infer changes in hypoxia within the tumor. Results: The optical probe measured nearly constant blood volume and a significant drop in hemoglobin saturation of about 30% after 10 Gy over the time scale of less than 30 minutes. The averaged R2* within the tumor volume increased by 15% after the 10 Gy dose, which is consistent with the optical results. The simulations and experiments support likely dynamic metabolic changes and/or fast vasoconstrictive signals are occurring that change the oxygen concentrations significantly, but not cell death or proliferation. Conclusion: Significant oxygen changes were observed to occur within 30 minutes, coinciding with the treatment time scale. This dynamic is very important for patient specific adaptive therapy. For hypofractionated therapy, the local instantaneous oxygen content is likely the most important variable to control. The invention of a bedside device for the purpose of measuring the instantaneous response to large radiation doses would be an important step to future improvements in outcome.

60 APPLIED LIFE SCIENCES↗

Scale-dependent bias and bispectrum in neutrino separate universe simulations

Cosmic background neutrinos have a large velocity dispersion, which causes the evolution of long-wavelength density perturbations to depend on scale. As such, this scale-dependent growth leads to the well-known suppression in the linear theory matter power spectrum that is used to probe neutrino mass. In this paper, we study the impact of long-wavelength density perturbations on small-scale structure formation. By performing separate universe simulations where the long-wavelength mode is absorbed into the local expansion, we measure the responses of the cold dark matter (CDM) power spectrum and halo mass function, which correspond to the squeezed-limit bispectrum and halo bias. We find that the scale-dependent evolution of the long-wavelength modes causes these quantities to depend on scale and provide simple expressions to model them in terms of scale and the amount of massive neutrinos. Importantly, this scale-dependent bias reduces the suppression in the linear halo power spectrum due to massive neutrinos by 13% and 26% for objects of bias b ¯ = 2 and b ¯ &#187 1 , respectively. We demonstrate with high statistical significance that the scale-dependent halo bias cannot be modeled by the CDM and neutrino density transfer functions at the time when the halos are identified. This reinforces the importance of the temporal nonlocality of structure formation, especially when the growth is scale dependent.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Force-extension curves for broken-rod macromolecules: Dramatic effects of different probing methods for two and three rods

We study force-extension curves of a single semiflexible chain consisting of several rigid rods connected by flexible spacers. The atomic force microscopy and laser optical or magnetic tweezers apparatus stretching these rod-coil macromolecules are discussed. In addition, the stretching by external isotropic force is analyzed. The main attention is focused on computer simulation and analytical results. We demonstrate that the force-extension curves for rod-coil chains composed of two or three rods of equal length differ not only quantitatively but also qualitatively in different probe methods. These curves have an anomalous shape for a chain of two rods. End-to-end distributions of rod-coil chains are calculated by Monte Carlo method and compared with analytical equations. The influence of the spacer’s length on the force-extension curves in different probe methods is analyzed. The results can be useful for interpreting experiments on the stretching of rod-coil block-copolymers.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Electromagnetic deep-probing (100-1000 KMS) of the Earth's interior from artificial satellites: Constraints on the regional emplacement of crustal resources

Model simulations show that induction in a spherical Earth by distant magnetospheric sources can contribute magnetic field fluctuations at MAGSAT altitudes which are 30 to 40 percent of the external field amplitudes. When the characteristic dimensions (e.g. depth of penetration, etc) of a particular situations are small compared with the Earth's radius, the Earth can be approximated by a plane horizontal half space. In this case, electromagnetic energy is reflected with close to 100 percent efficiency from the Earth's surface. This implies that the total horizontal field is twice the source field when the source is above the satellite, but is reduced to values which are much smaller than the source field when the source is below the satellite. This latter effect tends to enhance the signature of gross electrical discontinuities in the lithosphere when observed at satellite altitudes.

Hermance, J. F.↗

Gyrokinetic Particle Simulation of Turbulent Transport in Burning Plasmas

The SciDAC project at the IFS advanced the state of high performance computing for turbulent structures and turbulent transport. The team project with Prof Zhihong Lin [PI] at Univ California Irvine produced new understanding of the turbulent electron transport. The simulations were performed at the Texas Advanced Computer Center TACC and the NERSC facility by Wendell Horton, Lee Leonard and the IFS Graduate Students working in that group. The research included a Validation of the electron turbulent transport code using the data from a steady state university experiment at the University of Columbia in which detailed probe measurements of the turbulence in steady state were used for wide range of temperature gradients to compare with the simulation data. These results were published in a joint paper with Texas graduate student Dr. Xiangrong Fu using the work in his PhD dissertation.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Picosecond solvation dynamics—A potential viewer of DMSO—Water binary mixtures

In this work, we have investigated the composition dependent anomalous behavior of dimethyl sulfoxide (DMSO)-water binary mixture by collecting the ultrafast solvent relaxation response around a well known solvation probe Coumarin 480 (C480) by using a femtosecond fluorescence up-conversion spectrometer. Recent molecular dynamics simulations have predicted two anomalous regions of DMSO-water binary mixture. Particularly, these studies encourage us to investigate the anomalies from experimental background. DMSO-water binary mixture has repeatedly given evidences of its dual anomalous nature in front of our systematic investigation through steady-state and time-resolved measurements. We have calculated average solvation times of C480 by two individual well-known methods, among them first one is spectral-reconstruction method and another one is single-wavelength measurement method. The results of both the methods roughly indicate that solvation time of C480 reaches maxima in the mole fraction of DMSO X{sub D} = 0.12–0.17 and X{sub D} = 0.27–0.35, respectively. Among them, the second region (X{sub D} = 0.27–0.35) is very common as most of the thermodynamic properties exhibit deviation in this range. Most probably, the anomalous solvation trend in this region is fully guided by the shear viscosity of the medium. However, the first region is the most interesting one. In this region due to formation of strongly hydrogen bonded 1DMSO:2H{sub 2}O complexes, hydration around the probe C480 decreases, as a result of which solvation time increases.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Response of gravity level fluctuations on the Gravity Probe-B spacecraft propellant system

Time-dependent computations have been performed to investigate the dynamical behaviors of fluid under a microgravity environment. A computer algorithm is introduced which can be used to simulate the fluid behavior in that environment, in particular the excitation of sloshing waves due to different gravity environments and rotation speeds. A suggestion on the proper handling and managing of cryogenic fluid propellant to be used in the Gravity Probe-B spacecraft propulsion is made.

Hung, R. J.↗

Update on developments at SNIF

The Small Negative Ion Facility (SNIF) at CCFE has been undergoing continuous development and enhancement to both improve operational reliability and increase diagnostic capability. SNIF uses a CW 13.56MHz, 5kW RF driven volume source with a 30kV triode accelerator. Improvement and characterisation work includes: Installation of a new “L” type RF matching unit, used to calculate the load on the RF generator. Use of the electron suppressing biased insert as a Langmuir probe under different beam extraction conditions. Measurement of the hydrogen Fulcher molecular spectrum, used to calculate gas temperature in the source. Beam optimisation through parameter scans, using copper target plate and visible cameras, with results compared with AXCEL-INP to provide beam current estimate. Modelling of the beam power density profile on the target plate using ANSYS to estimate beam power and provide another estimate of beam current. This work is described, and has allowed an estimation of the extracted beam current of approximately 6mA (4mA/cm2) at 3.5kW RF power and a source pressure of 0.6Pa.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Nonlinear effects in ultrasound fields of diagnostic-type transducers used for kidney stone propulsion: Characterization in water

Newer imaging and therapeutic ultrasound technologies require higher in situ pressure levels compared to conventional diagnostic values. One example is the recently developed use of focused ultrasonic radiation force to move kidney stones and residual fragments out of the urinary collecting system. A commercial diagnostic 2.3 MHz C5-2 array probe is used to deliver the acoustic pushing pulses. The probe comprises 128 elements equally spaced at the 55 mm long convex cylindrical surface with 38 mm radius of curvature. The efficacy of the treatment can be increased by using higher intensity at the focus to provide stronger pushing force; however, nonlinear acoustic saturation can be a limiting factor. In this work nonlinear propagation effects were analyzed for the C5-2 transducer using a combined measurement and modeling approach. Simulations were based on the 3D Westervelt equation; the boundary condition was set to match the focal geometry of the beam as measured at a low power output. Focal waveforms simulated for increased output power levels were compared with the fiber-optic hydrophone measurements and were found in good agreement. It was shown that saturation effects do limit the acoustic pressure in the focal region of the transducer. This work has application to standard diagnostic probes and imaging.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Magnetic shielding of a laboratory Hall thruster. I. Theory and validation

We demonstrate a technique by which erosion of the acceleration channel in Hall thrusters can be reduced by at least a few orders of magnitude. The first principles of the technique, now known as “magnetic shielding,” have been derived based on the findings of 2-D numerical simulations. The simulations, in turn, guided the modification of an existing 6-kW laboratory Hall thruster to test the theory and are the main subject of this Part I article. Part II expands on the results of the experiments. Near the walls of the magnetically shielded (MS) thruster theory and experiment agree that (1) the plasma potential has been sustained at values near the discharge voltage, and (2) the electron temperature has been lowered compared to the unshielded thruster. Erosion rates deduced directly from the wall probes show reductions of at least ∼3 orders of magnitude at the MS inner wall when an ion energy threshold of 30.5 V is used in the sputtering yield model of the channel material. At the outer wall the probes reveal that the ion energy was below the assumed threshold. Using a threshold of 25 V, the simulations predict a minimum reduction of ∼600 at the MS inner wall. At the MS outer wall ion energies are found to be below 25 V. When a 50-V threshold is used the computed ion energies are below the threshold at both sides of the channel. Uncertainties, sensitivities, and differences between theory and experiment are also discussed. The elimination of wall erosion in Hall thrusters solves a problem that has remained unsettled for more than five decades.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Constraining the Higgs potential with neural simulation-based inference for di-Higgs production

Determining the form of the Higgs potential is one of the most exciting challenges of modern particle physics. Higgs pair production directly probes the Higgs self-coupling and should be observed in the near future at the High-Luminosity LHC. We explore how to improve the sensitivity to physics beyond the Standard Model through per-event kinematics for di-Higgs events. In particular, we employ machine learning through simulation-based inference to estimate per-event likelihood ratios and gauge potential sensitivity gains from including this kinematic information. In terms of the Standard Model Effective Field Theory, we find that adding a limited number of observables can help to remove degeneracies in Wilson coefficient likelihoods and significantly improve the experimental sensitivity.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Thermal Analysis of Small Re-Entry Probe

The Small Probe Reentry Investigation for TPS Engineering (SPRITE) concept was developed at NASA Ames Research Center to facilitate arc-jet testing of a fully instrumented prototype probe at flight scale. Besides demonstrating the feasibility of testing a flight-scale model and the capability of an on-board data acquisition system, another objective for this project was to investigate the capability of simulation tools to predict thermal environments of the probe/test article and its interior. This paper focuses on finite-element thermal analyses of the SPRITE probe during the arcjet tests. Several iterations were performed during the early design phase to provide critical design parameters and guidelines for testing. The thermal effects of ablation and pyrolysis were incorporated into the final higher-fidelity modeling approach by coupling the finite-element analyses with a two-dimensional thermal protection materials response code. Model predictions show good agreement with thermocouple data obtained during the arcjet test.

Agrawal, Parul↗

Experimental Studies of the Effect of Intent Information on Cockpit Traffic Displays

Intent information provides knowledge of another aircraft's current and future trajectory states. Prototype traffic displays were designed for four different levels of intent: Position, Rate, Commanded State, and FMS (Flight Management System)-Path. The current TCAS (traffic collision avoidance systems) Display, which shows altitude rate in addition to current position and altitude, was used as a baseline and represents the lowest level of intent. The Rate, Commanded State, and FMS-Path Displays show increasing levels of intent information using TCAS-like symbology in addition to incorporating a conflict probe and profile view display. An initial experiment was run on the MIT (Massachusetts Institute of Technology) Part Task Flight Simulator in which eight airline pilots flew five traffic scenarios with each of the four displays. Results show that pilots had fewer separation violations and maneuvered earlier with the three intent displays. Separation violations were reduced when pilots maneuvered earlier. A second experiment was run to compare performance between displaying intent information directly and incorporating it into a conflict probe. A different set of eight airline pilots flew four traffic scenarios with the TCAS and Commanded State Displays with and without the conflict probe. Conflict probes with two minute and long range look-ahead times were tested. Displaying conflict bands or showing intent information directly both led to fewer separation violations and earlier avoidance maneuvers than the base TCAS Display. Performance was similar between the two minute and long range look-ahead conflict probes. Pilots preferred all intent displays over the TCAS Display.

Barhydt, Richard↗

Dynamic PIC-simulations of charging phenomena related to the ICE-spacecraft in both cometary and solar wind environments

Spacecraft charging phenomena in the cometary environment of Giacobini-Zinner are less dramatic than expected. The potential of the ICE-probe is less than +1V in the vicinity of Giacobini-Zinner, while the potential may rise up to +6V in the solar wind environment. The paper presents results of PIC simulations that show the dominant influence of photoemission (photoelectrons or impact-induced electrons) in the presence of the solar wind core and halo electrons. Secondary electrons are also important in the cometary environment to explain positive potentials.

Thiemann, H.↗

Plasma Interaction with Electron-Emitting Surfaces

Electron emission from surfaces occurs in many plasma systems. Several types including secondary, thermionic and photon-induced emissions are intense under certain conditions. Understanding the effects of emission on the sheaths that govern plasma-surface interaction is important. This dissertation predicts some emitting sheath phenomena that were not reported in past studies. For example, most previous theoretical models assumed that an emitting sheath potential is always negative and that ions always accelerate into the wall. We show when the emission is intense that the sheath potential can become positive, fundamentally changing how the plasma and wall interact. In this inverse sheath state, ions are repelled, suggesting for instance that (a) no presheath exists in the plasma interior, (b) emitting walls could be used in applications to stop sputtering. Another topic considered is the transit of emitted electrons across the plasma to other surfaces, which is possible in low collisionality plasma systems. When transit occurs, the flux balance is a complex global problem where the sheaths at opposite surfaces are coupled through their exchange of emitted electrons. We also show that secondary emission can trigger a variety of sheath instability phenomena that change the state of the plasma-wall system or cause oscillations preventing steady state. Lastly, we analyze a mechanism where emitted electrons return to the same surface and knock out secondaries, which return and knock out more secondaries, etc., feedback amplifying the emission intensity. The four phenomena will be analyzed theoretically and verified with particle-in-cell simulations: (a) inverse sheath, (b) sheath coupling via transiting electrons, (c) sheath instabilities, (d) returning electron amplification. Consequences of these processes on the sheath potentials, wall heating, loss rate of charge, and cross field transport (near-wall conductivity) are discussed throughout. Possible implications are suggested for fusion machines, plasma propulsion engines, probes, dusty plasmas, RF discharges, and surfaces in space.

Fusion↗

Inherit Space

The objective of the proposed research was to begin development of a unique educational tool targeted at educating and inspiring young people 12-16 years old about NASA and the Space Program. Since these young people are the future engineers, scientists and space pioneers, the nurturing of their enthusiasm and interest is of critical importance to the Nation. This summer the basic infrastructure of the tool was developed in the context of an educational game paradigm. The game paradigm has achieved remarkable success in maintaining the interest of young people in a self-paced, student-directed learning environment. This type of environment encourages student exploration and curiosity which are exactly the traits that future space pioneers need to develop to prepare for the unexpected. The Inherit Space Educational Tool is an open-ended learning environment consisting of a finite-state machine classic adventure game paradigm. As the young person explores this world, different obstacles must be overcome. Rewards will be offered such as using the flight simulator to fly around and explore Titan. This simulator was modeled on conventional Earth flight simulators but has been considerably enhanced to add texture mapping of Titan's atmosphere utilizing the latest information from the NASA Galileo Space Probe. Additional scenery was added to provide color VGA graphics of a futuristic research station on Titan as well as an interesting story to keep the youngster's attention. This summer the game infrastructure has been developed as well as the Titan Flight Simulator. A number of other enhancements are planned.

Giarratano, Joseph C.↗

SU-E-QI-15: Single Point Dosimetry by Means of Cerenkov Radiation Energy Transfer (CRET)

Purpose: Cerenkov light is generated when a charged particles with energy greater then 250 keV, moves faster than the speed of light in a given medium. Both x-ray photons and electrons produce optical Cerenkov photons during the static megavoltage linear accelerator (LINAC) operational mode. Recently, Cerenkov radiation gained considerable interest as possible candidate as a new imaging modality. Optical signals generated by Cerenkov radiation may act as a surrogate for the absorbed superficial radiation dose. We demonstrated a novel single point dosimetry method for megavoltage photon and electron therapy utilizing down conversion of Cerenkov photons. Methods: The custom build signal characterization system was used: a sample holder (probe) with adjacent light tight compartments was connected via fiber-optic cables to a photon counting photomultiplier tube (PMT). One compartment contains a medium only while the other contains medium and red-shifting nano-particles (Q-dots, nanoclusters). By taking the difference between the two signals (Cerenkov photons and CRET photons) we obtain a measure of the down-converted light, which we expect to be proportional to dose as measured with an adjacent ion chamber. Experimental results are compared to Monte Carlo simulations performed using the GEANT4 code. Results: The signal correlation between CR signal, CRET readings and dose produced by LINAC at a single point were investigated. The experimental results were compared with simulations. The dose linearity, signal to noise ratio and dose rate dependence were tested with custom build CRET based probe. Conclusion: Performance characteristics of the proposed single point CRET based probe were evaluated. The direct use of the induced Cerenkov emission and CRET in an irradiated single point volume as an indirect surrogate for the imparted dose was investigated. We conclude that CRET is a promising optical based dosimetry method that offers advantages over those already proposed.

60 APPLIED LIFE SCIENCES↗

Time-resolved photoelectron spectroscopy via trajectory surface hopping

Time-resolved photoelectron spectroscopy is a powerful pump-probe technique which can probe nonadiabatic dynamics in molecules. Interpretation of the experimental signals however requires input from theoretical simulations. Advances in electronic structure theory, nonadiabatic dynamics, and theory to calculate the ionization yields, have enabled accurate simulation of time-resolved photoelectron spectra leading to successful applications of the technique. Here, we review the basic theory and steps involved in calculating time-resolved photoelectron spectra, and highlight successful applications.

Chakraborty, Pratip↗