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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,243 records · Page 69
All sourcesNASA NTRSDOE OSTI
NASA NTRS1994

Skeletal unloading induces resistance to insulin-like growth factor I

In previous studies with a hindlimb elevation model, we demonstrated that skeletal unloading transiently inhibits bone formation. This effect is limited to the unloaded bones (the normally loaded humerus does not cease growing), suggesting that local factors are of prime importance. IGF-I is one such factor; it is produced in bone and stimulates bone formation. To determine the impact of skeletal unloading on IGF-I production and function, we assessed the mRNA levels of IGF-I and its receptor (IGF-IR) in the proximal tibia and distal femur of growing rats during 2 weeks of hindlimb elevation. The mRNA levels for IGF-I and IGF-IR rose during hindlimb elevation, returning toward control values during recovery. This was accompanied by a 77% increase in IGF-I levels in the bone, peaking at day 10 of unloading. Changes in IGF binding protein levels were not observed. Infusion of IGF-I (200 micrograms/day) during 1 week of hindlimb elevation doubled the increase in bone mass of the control animals but failed to reverse the cessation of bone growth in the hindlimb-elevated animals. We conclude that skeletal unloading induces resistance to IGF-I, which may result secondarily in increased local production of IGF-I.

NASA Center ARC↗
NASA NTRS2025

Mechanics of Preloaded Bolt Tensile Loading With Focus on Load Introduction Factor

The bolt tensile and joint separation loads are directly influenced by the locations at which the external loads enter the clamped members of a preloaded bolted joint (PBJ) and the associated load-paths through the joint. This physical load introduction mechanism affecting the bolt tensile loading is typically represented in the bolt tensile load equation, in part, by a load introduction factor (LIF), which was shown by H.M. Lee of Marshall Spaceflight Center to be a natural product of the bolt tensile load equation using a linear spring stiffness model. This LIF, being a function of load-path stiffness, has subsequently been denoted as the stiffness-based LIF (SBLIF), providing a framework to calculate the LIF using whatever load-path stiffness approximations are appropriate. Expanding upon the work of Lee, it is shown that the SBLIF and the joint stiffness factor are functions of the stiffnesses of the same load-paths and regions within a PBJ, and thus they should not be treated as independent variables. Mathematical expressions for the SBLIF are presented. Comparisons are shown between the analytically calculated SBLIF, the analytically calculated geometric LIF (GLIF), which is a simple clamped-member thickness ratio, the experimentally derived LIF, and the LIF determined by finite element analysis (FEA). Using experiment and FEA as a benchmark, the SBLIF, using traditional load-path stiffness approximations, enables a more accurate prediction of bolt tensile loading than the GLIF, although it can be unconservative near joint separation. The GLIF generally attributes more of the externally applied tensile load to the bolt than does the SBLIF, potentially resulting in heavier and/or more costly bolted joints. Mathematical relationships between the SBLIF and the GLIF are developed. Supplemental material is provided in the appendixes where the historical practice of using the joint compressive stiffness in place of the joint tensile stiffness is evaluated. The appendixes include step-by-step examples demonstrating the calculation of the SBLIF using traditional stiffness approximations and conclude with the development of the joint diagram in terms of the SBLIF, culminating into formulas for the key features of a joint diagram, which is useful for programming.

Load Path↗
DOE OSTI2017

The human factors verification at plant startup for the AP1000 Plant - 173

The Human Factors (HF) verification at plant startup is the final HF assessment for the AP1000{sup R} HF program and is performed using the as-built plant design. This HF verification has been implemented for the China AP1000 Standard Plant. The scope and objectives of the HF verification at plant startup met the requirements for Verification and Validation (V and V) as described in NUREG-0711, 'Human Factors Engineering Program Review Model'. The majority of the verifications have been completed. Overall, the results confirmed the adequacy of the China AP1000 Standard Plant operating procedures and operator training. A number of design issues were identified and were categorized as safety issues, operability and maintainability issues or minor issues. These issues are being addressed and tracked as site test deficiencies. Based on the current results, it can be concluded that the China AP1000 Standard Plant is safe, operable and maintainable, pending completion of the outstanding verifications and resolution of the identified issues. This paper will describe the overall strategy and discuss the lessons learned in respect to providing HF support to the startup activities for the AP1000 plant. (authors)

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗
DOE OSTI2017

Optimization of human factors methods within the design cycle - 178

Amec Foster Wheeler developed and implemented the Human Factors Engineering program to analyze the design of a large-scale electrical component readying for installation in a nuclear facility. The HFE program applied the program elements from NUREG-0711 throughout the detailed design phase of the project. This paper provides: (1) a review of the Human Factors Engineering (HFE) program methodology that was implemented, and (2) a summary of the integrated approach to the design, verification, and validation of the Human-Machine Interface (HMI) display and mimic panel. In general, it was found that a collaborative approach between the design team, equipment vendor, HFE, and the end-users of the component created a more streamlined approach to the design and allowed for user feedback to be implemented throughout the progression of the design. However, the trade-off to this approach is that an integrated validation is likely required once all design aspects are complete, to ensure the modification is acceptable in the context of the overall system. (authors)

42 ENGINEERING↗
DOE OSTI2017

An overview of the IEEE human factors standard development activities - 2017 - 230

Since 1980 the Institute of Electrical and Electronics Engineers (IEEE) has supported development of human factors (HF) standards. Within IEEE, Subcommittee 5 (SC5) of the Nuclear Power Engineering Committee develops and maintains HF standards applicable to nuclear facilities. These standards are structured in a hierarchical fashion. The top-level standard defines the HF tasks required to support the integration of human performance into the design process. Five lower tier documents expand upon the upper tier standard. Presently, two new HF standards projects are underway; one to provide HF guidance for the validation of the system interface design and integrated systems operation and another for designing and developing computer-based displays for monitoring and control of nuclear facilities. In addition to producing and maintaining HF standards, SC5 is also involved in outreach activities, including sponsorship of a series of conferences on human factors and nuclear power plants. (authors)

22 GENERAL STUDIES OF NUCLEAR REACTORS↗
DOE OSTI2017

Application of eye tracking for measurement and evaluation in human factors studies in control room modernization - 309

An important element of human factors engineering (HFE) pertains to measurement and evaluation (M and E). The role of HFE-M and E should be integrated throughout the entire control room modernization (CRM) process and be used for human-system performance evaluation and diagnostic purposes with resolving potential human engineering deficiencies (HEDs) and other human machine interface (HMI) design issues. NUREG-0711 describes how HFE in CRM should employ a hierarchical set of measures, particularly during integrated system validation (ISV), including plant performance, personnel task performance, situation awareness, cognitive workload, and anthropometric/ physiological factors. Historically, subjective measures have been primarily used since they are easier to collect and do not require specialized equipment. However, there are pitfalls with relying solely on subjective measures in M and E such that negatively impact reliability, sensitivity, and objectivity. As part of comprehensively capturing a diverse set of measures that strengthen findings and inferences made of the benefits from emerging technologies like advanced displays, this paper discusses the value of using eye tracking as an objective method that can be used in M and E. A brief description of eye tracking technology and relevant eye tracking measures is provided. Additionally, technical considerations and the unique challenges with using eye tracking in full-scaled simulations are addressed. Finally, this paper shares preliminary findings regarding the use of a wearable eye tracking system in a full-scale simulator study. These findings should help guide future full-scale simulator studies using eye tracking as a methodology to evaluate human-system performance. (authors)

22 GENERAL STUDIES OF NUCLEAR REACTORS↗
DOE OSTI2021

Using Preformed Meisenheimer Complexes as Dopants for n-Type Organic Thermoelectrics with High Seebeck Coefficients and Power Factors

A pre-formed Meisenheimer complex of a naphthalenediimide (NDI) with tetrabutylammonium fluoride (TBAF) is obtained in a simple way by mixing dibrominated 4,9-dibromo-2,7-bis(2-octyldodecyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone and TBAF in solution and used as a dopant for n-type organic thermoelectrics. Additionally, two n-type polymers PNDIClTVT and PBDOPVTT are synthesized, n-doped, and characterized as conductive and thermoelectric materials. PNDIClTVT doped with NDI-TBAF presents a high σ value of 0.20 S cm –1 , a Seebeck coefficient (S) of -1854 µV K –1 , and a power factor (PF) of 67 µW m –1 K –2 , among the highest reported PF in solution-processed conjugated n-type polymer thermoelectrics. Using 4-(1,3-dimethyl-2,3-dihydro-1H-benzoimidazol-2-yl)phenyl)dimethylamine and NDI-TBAF as co-dopants, PNDIClTVT has a PF > 35 µW m –1 K –2 ; while for PBDOPVTT σ = 0.75 S cm –1 and PF = 58 µW m –1 K –2 . In this study it is found that an ionic adduct together with a neutral dopant improves the performance of n-type organic thermoelectrics leading to an enhanced power factor, and more generally, the role of such an adduct in polymer doping is also elucidated.

36 MATERIALS SCIENCE↗
DOE OSTI2023

Solution–Doped Donor–Acceptor Copolymers Based on Diketopyrrolopyrrole and 3, 3'–Bis (2–(2–(2–Methoxyethoxy) Ethoxy) ethoxy)–2, 2'–Bithiophene Exhibiting Outstanding Thermoelectric Power Factors with p –Dopants

The design of polymeric semiconductors exhibiting high electrical conductivity (σ) and thermoelectric power factor (PF) will be vital for flexible large-area electronics. In this work, four polymers based on diketopyrrolopyrrole (DPP), 2,3-dihydrothieno[3,4-b][1,4]dioxine (EDOT), thieno[3,2-b]thiophene (TT), and 3, 3'-bis (2-(2-(2-methoxyethoxy) ethoxy) ethoxy)-2, 2'-bithiophene (MEET) are investigated as side-chains, with the MEET polymers newly synthesized for this study. These polymers are systematically doped with tetrafluorotetracyanoquinodimethane ( F 4 TCNQ), CF3SO3H, and the synthesized dopant Cp(CN) 3 -(COOMe) 3 , differing in geometry and electron affinity. The DPP-EDOT-based polymer containing MEET as side-chains exhibits the highest conductivity (σ) ≈700 S cm–1 in this series with the acidic dopant (CF 3 SO 3 H). This polymer also shows the lowest oxidation potential by cyclic voltammetry (CV), the strongest intermolecular interactions evidenced by differential scanning calorimetry (DSC), and has the most oxygen-based functionality for possible hydrogen bonding and ionic screening. Other polymers exhibit high σ ≈300–500 S cm–1 and power factor up to 300 µW m –1 K –2 . The mechanism of conductivity is predominantly electronic, as validated by time-dependent conductance studies and transient thermo voltage monitoring over time, including for those doped with the acid. Furthermore, these materials maintain significant thermal stability and air stability over ≈6 weeks. Density functional theory calculations reveal molecular geometries and inform about frontier energy levels. Raman spectroscopy, in conjunction with scanning electron microscopy (SEM-EDS) and x-ray diffraction, provides insight into the solid-state microstructure and degree of phase separation of the doped polymer films. Infrared spectroscopy enables this study to further quantify the degree of charge transfer from polymer to dopant.

36 MATERIALS SCIENCE↗
DOE OSTI2015

Is $50/MWh solar for real? Falling project prices and rising capacity factors drive utility-scale PV toward economic competitiveness

Recently announced low-priced power purchase agreements (PPAs) for US utility-scale photovoltaic (PV) projects suggest $50/MWh solar might be viable under certain conditions. To explore this possibility, this paper draws on an increasing wealth of empirical data to analyze trends in three of the most important PPA price drivers: upfront installed project prices, operations, and maintenance (O&M) costs, and capacity factors. Average installed prices among a sample of utility-scale PV projects declined by more than one third (from 5.8/W AC to 3.7/WAC) from the 2007–2009 period through 2013, even as costlier systems with crystalline-silicon modules, sun tracking, and higher inverter loading ratios (ILRs) have constituted an increasing proportion of total utility-scale PV capacity (all values shown here are in 2013 dollars). Actual and projected O&M costs from a very small sample of projects appear to range from $20–$40/kW AC -year. Furthermore, the average net capacity factor is 30% for projects installed in 2012, up from 24% for projects installed in 2010, owing to better solar resources, higher ILRs, and greater use of tracking among the more recent projects. Based on these trends, a pro-forma financial model suggests that $50/MWh utility-scale PV is achievable using a combination of aggressive-but-achievable technical and financial input parameters (including receipt of the 30% federal investment tax credit). Although the US utility-scale PV market is still young, the rapid progress in the key metrics documented in this paper has made PV a viable competitor against other utility-scale renewable generators, and even conventional peaking generators, in certain regions of the country.

14 SOLAR ENERGY↗
DOE OSTI2015

Simvastatin mitigates increases in risk factors for and the occurrence of cardiac disease following 10 Gy total body irradiation

The ability of simvastatin to mitigate the increases in risk factors for and the occurrence of cardiac disease after 10 Gy total body irradiation (TBI) was determined. This radiation dose is relevant to conditioning for stem cell transplantation and threats from radiological terrorism. Male rats received single dose TBI of 10 Gy. Age-matched, sham-irradiated rats served as controls. Lipid profile, heart and liver morphology and cardiac mechanical function were determined for up to 120 days after irradiation. TBI resulted in a sustained increase in total- and LDL-cholesterol (low-density lipoprotein-cholesterol), and triglycerides. Simvastatin (10 mg/kg body weight/day) administered continuously from 9 days after irradiation mitigated TBI-induced increases in total- and LDL-cholesterol and triglycerides, as well as liver injury. TBI resulted in cellular peri-arterial fibrosis, whereas control hearts had less collagen and fibrosis. Simvastatin mitigated these morphological injuries. TBI resulted in cardiac mechanical dysfunction. Simvastatin mitigated cardiac mechanical dysfunction 20–120 days following TBI. To determine whether simvastatin affects the ability of the heart to withstand stress after TBI, injury from myocardial ischemia/reperfusion was determined in vitro. TBI increased the severity of an induced myocardial infarction at 20 and 80 days after irradiation. Simvastatin mitigated the severity of this myocardial infarction at 20 and 80 days following TBI. It is concluded simvastatin mitigated the increases in risk factors for cardiac disease and the extent of cardiac disease following TBI. This statin may be developed as a medical countermeasure for the mitigation of radiation-induced cardiac disease.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2018

Total Protein Content Determination of Microalgal Biomass by Elemental Nitrogen Analysis and a Dedicated Nitrogen-to-Protein Conversion Factor

Accurately determining protein content is important in the valorization of algal biomass in food, feed, and fuel markets, where these values are used for component balance calculations. Conversion of elemental nitrogen to protein is a well-accepted and widely practiced method, but depends on developing an applicable nitrogen-to-protein conversion factor. The methodology reported here covers the quantitative assessment of the total nitrogen content of algal biomass and a description of the methodology that underpins the accurate de novo calculation of a dedicated nitrogen-to-protein conversion factor.

09 BIOMASS FUELS↗
DOE OSTI2018

Tracking of Nuclear Cable Insulation Polymer Structural Changes using the Gel Fraction and Uptake Factor Method

Cross-linked polyethylene (XLPE) cable insulation samples were exposed to heat and gamma radiation at a series of temperatures, dose rates, and exposure times to evaluate the effects of these variables on material degradation. The samples were tested using the solvent incubation method to collect gel fraction and uptake factor data in order to assess the crosslinking and chain scission occurring in polymer samples with aging. Consistent with previous reports, gel fraction values were observed to increase and uptake factor values to decrease with radiation and thermal exposure. The trends seen were also more prominent as exposure time increased, suggesting this to be a viable method of tracking structural changes in the XLPE-insulated cable material over extended periods. For the conditions explored, the cable insulation material evaluated did not indicate signs of anomalous aging such as inverse temperature effect in which radiation-induced aging is more severe at lower temperature. Ongoing aging under identical radiation conditions and at lower temperature will further inform conclusions regarding the importance of inverse temperature effects for this material under these conditions.

cable aging↗
DOE OSTI2019

Nuclear Factor-κB is Activated in Filter-Implanted Vena Cava

Background: Implantation of a retrievable vena cava filter (VCF) is an effective method for preventing pulmonary embolism. Retrieval of filters, however, may be difficult due to intimal hyperplasia and inflammation in the cava wall. The transcription factor nuclear factor-kappaB (NF-κB) plays an important role in regulation of numerous genes participating in the inflammatory and proliferative responses of cells. The present study was to determine whether VCF implantation resulted in activation of NF-κB in the venous neointima. Methods: Filters were placed in vena cava (VC) in four swine for 30 days and then removed. Intimal specimens adhering to the filter struts were analyzed with reference to normal VC tissues. Immunohistochemical analyses were used to assess the NF-κB subunits p65 and p50 and the phosphorylated inhibitor of κB-α (phosphor-IκB-α) in the tissues. NF-κB DNA-binding activity was measured with enzyme-linked immunosorbent assay. Results: As compared to normal VC tissues, the intimal tissues contained higher percentages of cell nucleus-located p65 and p50, and NF-κB DNA-binding activity. Elevated immunoreactivities of p65, p50 and phosphor-IκB-α were also present in the intima. Conclusion: The present study demonstrates for the first time that VCF implantation caused NF-κB activation in neointima. We further demonstrate the activation is at least partly due to phosphorylation of IκB-α. Our data suggest that NF-κB activation would significantly contribute to development of intimal hyperplasia and inflammation in filter-inserted vena cava walls. NF-κB might be a therapeutic target for inhibiting filter-induced neointima and improving filter retrieval.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2018

Factorization of generalized γ-generating matrices

The class of γ-generating matrices and its subclasses of regular and singular γ-generating matrices were introduced by D. Z. Arov in [8], where it was shown that every γ-generating matrix admits an essentially unique regular–singular factorization. The class of generalized γ-generating matrices was introduced in [14, 20]. In the present paper, subclasses of singular and regular generalized –generating matrices are introduced and studied. As the main result, a theorem of existence of the regular–singular factorization for a rational generalized γ-generating matrix is proved.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2022

Derivation and assessment of regional electricity generation emission factors in the USA

Electricity production is one of the largest sources of environmental emissions - especially greenhouse gases (GHGs) - in the USA. Emission factors (EFs) vary from region to region, which requires the use of spatially relevant EF data for electricity production while performing life cycle assessments (LCAs). Uncertainty information, which is sought by LCA practitioners, is rarely supplied with available life cycle inventories (LCIs). To address these challenges, we present a method for collecting data from different sources for electricity generation and environmental emissions; discuss the challenges involved in agglomerating such data; provide relevant suggestions and solutions to merge the information; and calculate EFs for electricity generation processes from various fuel sources for different spatial regions and spatial resolutions. The EFs from the US 2016 Electricity Life Cycle Inventory (eLCI) are analyzed and explored in this study. We also explore the method of uncertainty information derivation for the EFs. We explore the EFs from different technologies across Emissions & Generation Resource Integrated Database (eGRID) regions in the USA. We find that for certain eGRID regions, the same electricity production technology may have worse emissions. This may be a result of the age of the plants in the region, the quality of fuel used, or other underlying factors. Region-wise life cycle impact assessment (LCIA) ISO 14040 impacts for total generation mix activities provide an overview of the total sustainability profile of electricity production in a particular region, rather than only global warming potential (GWP). We also find that, for different LCIA impacts, several eGRID regions are consistently worse than the US average LCIA impact for every unit of electricity generated. Here this work describes the development of an electricity production LCI at different spatial resolutions by combining and harmonizing information from several databases. The inventory consists of emissions, fuel inputs, and electricity and steam outputs from different electricity production technologies located across various regions of the USA. This LCI for electricity production in the USA will prove to be an enormous resource for all LCA researchers - considering the detailed sources of the information and the breadth of emissions covered by it.

24 POWER TRANSMISSION AND DISTRIBUTION↗
DOE OSTI2017

Dependence of twinned volume fraction on loading mode and Schmid factor in randomly textured magnesium

Here, the twinning activity in random textured cast magnesium during room temperature tension and compression tests was monitored by neutron diffraction (ND). Variation of integrated intensities of selected diffraction peaks, characterizing the twinned volume in particularly oriented grains was compared with calculated Schmid factors for extension twinning of these grains. It is shown that in tension there is a direct proportion between the twinned volume and the maximum value of the Schmid factor for a given grain orientation. In contrast, in compression this relation is not valid. The twinned volume in this case is influenced by both deviation of the grain from the ideal orientation and its rotation around the c-axis. The experimental results are in good agreement with those obtained from elasto-plastic self-consistent (EPSC) modeling.

36 MATERIALS SCIENCE↗
DOE OSTI2015

Structure factors for tunneling ionization rates of diatomic molecules

Within the leading-order, single-active-electron, and frozen-nuclei approximation of the weak-field asymptotic theory, the rate of tunneling ionization of a molecule in an external static uniform electric field is determined by the structure factor for the highest occupied molecular orbital. We present the results of systematic calculations of structure factors for 40 homonuclear and heteronuclear diatomic molecules by the Hartree–Fock method using a numerical grid-based approach implemented in the program X2DHF.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2025

A mathematical approach to using the forgetting curve to evaluate experience and training factors in human reliability analysis

Traditional human reliability analysis (HRA) methods have difficulty dealing with the dynamic nature of factors such as time and rely on static and expert-judgment-based assessments of performance-shaping factors (PSFs) across limited levels. In this study, we introduce a mathematical approach for dynamically evaluating the experience and training PSF. Our proposed method integrates the psychological concept of the “forgetting curve” to evaluate how PSFs are impacted by the number of trainings and the time elapsed since training. To confirm the validity of the model, we provide experimental data fitted by identifying the quantitative relationship between training and human performance. This research enables dynamic and objective assessments, thus reducing reliance on subjective expert judgment and improving the accuracy of HRA.

99 - GENERAL AND MISCELLANEOUS↗