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At least 127 records · Page 7

malbacR: A Package for Standardized Implementation of Batch Correction Methods for Omics Data

Mass spectrometry is a powerful tool for identifying and analyzing small molecules, such as metabolites and lipids, in com-plex biological samples. Liquid chromatography and gas chromatography mass spectrometry studies quite commonly in-volve large numbers of samples, which can require significant time for sample preparation and analyses. To accommodate such studies, the samples are commonly split into batches. Inevitably, variations in sample handling, temperature fluctua-tion, imprecise timing, column degradation and other factors result in systematic errors or biases of the measured abundances between the batches. Numerous methods are available via R packages to assist with batch correction for small molecule om-ics data; however, since these methods were developed by different research teams, the algorithms are available in separate R packages, each with different data input and output formats. We introduce the malbacR package which consolidates eleven common batch effect correction methods for small molecule omics data into one place so users can easily implement and compare: pareto scaling, power scaling, range scaling, ComBat, EigenMS, NOMIS, RUV-random, QC-RLSC, WaveI-CA2.0, TIGER, and SERRF. The malbacR package standardizes data input and output formats across these batch correction methods. The package works in conjunction with the pmartR package, allowing users to seamlessly include batch effect cor-rection in a pmartR workflow without needing any additional data manipulation.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Destructive Examination of Shipping Package 9975-02731

Destructive and non-destructive examinations were performed on the components of the package 9975-02731 as part of a comprehensive Savannah River Site surveillance program for plutonium materials stored in the K-Area Complex (KAC). The package stored nuclear materials in KAC for 13.8 years. Inspection of the package during opening in KAC noted one non-conforming condition: a large discolored area on the upper fiberboard subassembly. The package was subsequently transferred to Savannah River National Laboratory for more detailed examination. In addition to the observation noted in KAC, the following conditions were observed: (1) Axial gap of 1.021 inch slightly exceeded the 1 inch maximum criterion, and (2) Lead shield height exceeded drawing tolerance of 24.7 inch by 0.019 inch. Visual examination of the upper fiberboard assembly and analysis of the discolored fiberboard indicate the discoloration was due to wood glue residue. The physical, thermal, and mechanical properties of the fiberboard met the acceptance criteria and/or were within the range of previously tested fiberboard and baseline samples. The visual, microscopic and tensile testing results were consistent with previous O-ring and baseline Viton results. The lead shield surface was covered with corrosion product as observed on other shields but there was no evidence of excessive blistering, flaking, or spalling. Besides minor and expected corrosion, no evidence of a degraded condition was found in this package. Examination of the 9975-02731 corroborates existing evidence that the 9975 package is robust and the components can perform their expected functions.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

500 C Electronic Packaging and Dielectric Materials for High Temperature Applications

High-temperature environment operable sensors and electronics are required for exploring the inner solar planets and distributed control of next generation aeronautical engines. Various silicon carbide (SiC) high temperature sensors, actuators, and electronics have been demonstrated at and above 500C. A compatible packaging system is essential for long-term testing and application of high temperature electronics and sensors. High temperature passive components are also necessary for high temperature electronic systems. This talk will discuss ceramic packaging systems developed for high temperature electronics, and related testing results of SiC circuits at 500C and silicon-on-insulator (SOI) integrated circuits at temperatures beyond commercial limit facilitated by these high temperature packaging technologies. Dielectric materials for high temperature multilayers capacitors will also be discussed. High-temperature environment operable sensors and electronics are required for probing the inner solar planets and distributed control of next generation aeronautical engines. Various silicon carbide (SiC) high temperature sensors, actuators, and electronics have been demonstrated at and above 500C. A compatible packaging system is essential for long-term testing and eventual applications of high temperature electronics and sensors. High temperature passive components are also necessary for high temperature electronic systems. This talk will discuss ceramic packaging systems developed for high electronics and related testing results of SiC circuits at 500C and silicon-on-insulator (SOI) integrated circuits at temperatures beyond commercial limit facilitated by high temperature packaging technologies. Dielectric materials for high temperature multilayers capacitors will also be discussed.

dielectric performance↗

Codisposal Waste Package Loading Options for DOE SNF and HLW

The U.S. Department of Energy (DOE) is responsible for managing spent nuclear fuel (SNF) that is currently in, or will in the future come into, its possession. DOE must continue to safely store that SNF, transport it to an interim storage site or a repository, and dispose of it. These fuels come from a wide range of reactor types, such as light- and heavy-water-moderated reactors, graphite-moderated reactors, and breeder reactors, with various cladding materials and enrichments. Many of these reactors, now decommissioned, had unique design features, such as core configuration, fuel element and assembly geometry, moderator and coolant materials, operational characteristics, and neutron spatial and spectral properties resulting in a large diversity of reactor and fuel designs. Because of the wide variety and condition of SNF, a robust canister termed the DOE Standardized SNF Canister was proposed that would confine radionuclides and preclude moderator. The DOE Standard SNF Canister had four variations consisting of a 10- or 15-foot length and an 18- or 24-inch diameter. For ultimate disposal in the Yucca Mountain Repository these canisters were to be grouped with 24-inch diameter HLW canisters in a codisposal waste package. The 18-inch DOE Standardized SNF Canister could be placed in the middle of five HLW canisters. The 24-inch DOE Standardized SNF Canister would take the place of one the five HLW canister on the outer ring in the codisposal waste package. No DOE Standardized SNF Canisters have been loaded, and many fuel types can be loaded in multiple canisters. Depending on the selected diameter of the DOE Standardized SNF Canister for a particular fuel, the number of potential codisposal waste packages could vary. In addition, different types of DOE SNF may be able to be combined in a single canister. This could significantly change the number of DOE SNF canisters that are loaded and result in a decrease of the number of total potential codisposal waste packages. Ultimately, if too many HLW canisters need disposition, then a reduction in the number of DOE Standardized SNF Canisters will change the final total of codisposal waste packages very little. Likewise, if the ratio of DOE Standardized SNF Canisters to HLW canister produced is too high, then DOE Standardized SNF Canisters will not have enough HLW canisters to surround them in the codisposal waste package. This paper examines the results of differing loading strategies for a few DOE SNFs. It also compares the ranges of DOE Standardized SNF Canisters that may be produced to the ranges of HLW canisters that may be produced in order to determine potential scenarios.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

An Organic, Direct Bonded Copper, Multi-Layered, Ultra-Low Inductance Package for High-Power UWBG MOSFETs

The most common metalized substrates used in high-power switching packages consist of a ceramic layer such as Aluminum Nitride (AlN) sandwiched between two copper layers. Ceramic substrates are used because it has the key characteristic of having high dielectric strength while being thermally conductive. A large drawback to ceramic substrates is that they do not allow for a multi-layered circuit design. By replacing the traditional ceramic substrate with organic direct bonded copper (ODBC) we can open a wide range of possibilities when it comes to power module layout such as multi-layered circuits and double-sided cooling. Both benefits are critical while packaging high-performance Gallium Oxide (Ga2O3) MOSFETs. Because of Ga2O3's relatively poor thermal conductivity, a double-sided cooled package becomes necessary. Therefore, the use of ODBC provides the flexibility to fabricate copper traces carrying much higher currents, and by creating a multi-layered package, we can drastically reduce the parasitic inductance inside the power module. Achieving lower parasitic inductance is critical for an ultra-fast Ga2O3 package to avoid excessive voltage overshoot and ringing. Using ODBC, we have designed novel packages capable of handling the challenges presented by fast Ga2O3 switching. Using multi-physics modeling software, we can validate our design before building the prototype. Due to the simple process parameters needed to work with ODBC, we can rapidly create prototypes without using external vendors. This flexibility allows us to quickly design, build, and validate highly complex switching power modules to accommodate next generation, Ga2O3 switching devices.

ADVANCED PROPULSION SYSTEMS,ENGINEERING↗

Real time side-by-side experimental validation of energy and comfort performance of a zero net energy retrofit package for small commercial buildings

Making buildings zero-net energy (ZNE) is one of the major strategies for achieving carbon emission reduction goals. For this strategy to be successful, it entails a very significant reduction in energy use – 50% or more. In small commercial buildings, however, owners and building management teams usually have limited resources for identifying, analyzing, and procuring appropriate retrofit measures for reducing such use. An approach to overcome this limitation is the development of bundles of energy efficiency measures that can be presented to building owners/operators as a comprehensive package. The research presented in this paper focuses on an experimental evaluation of the impacts of a retrofit package developed for small office buildings in California. Performing this evaluation in a full-scale whole-building integrated systems test facility allowed a side-by-side evaluation in real time, against a reference case, of the impact of the retrofit package not only on energy use but also on visual and thermal comfort. Here, the retrofit package evaluated is comprised of a combination of HVAC, lighting (including daylighting), and plug load measures. The evaluation occurred at different times of the year in order to account for seasonal variations in environmental conditions, including solar angles and weather. The experimental facility allowed testing for two different façade orientations: south and west. Results show that the proposed ZNE retrofit package can save significant amounts of energy for small commercial buildings. During cooling-prevalent periods, total energy savings were 65% for south orientation and 68% for west orientation; during heating-prevalent periods total energy savings were 22% for south orientation and 25% for west orientation. Measurements indicate that the ZNE retrofit package resulted in small but not very significant changes in comfort levels for building occupants.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Demonstration of object location, classification, and characterization by developed deep learning dust ablation trail analysis code package using plasma jets

Based on deep learning, a Dust Ablation Trail Analysis (DATA) code package is developed to detect dust ablation trails in tokamaks, which is intended to analyze a large amount data of tokamak dusts. To validate and benchmark the DATA code package, 2440 plasma jet images are exploited for the training and test of the deep learning DATA code package, since plasma jets resemble the shape and size of dust ablation clouds in tokamaks. After being trained by 1920 plasma jet images, the DATA code package is able to locate 100% plasma jets, classify plasma jets with the accuracy of >99.9%, and output image skeleton information for classified plasma jets. The DATA code package trained by the plasma jet images is also used to analyze the dust ablation trails captured in the Experimental Advanced Superconducting (EAST) tokamak with the satisfactory performance, further verifying its applicability in the fusion dust ablation investigation. Based on its excellent performance presented here, it is demonstrated that our DATA code package is able to automatically identify and analyze dust ablation trails in tokamaks, which can be used for further detailed investigations, such as the three-dimensional reconstruction of dusts and their ablation trails.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

CMaize: Simplifying inter-package modularity from the build up

There is a growing desire for inter-package modularity within the chemistry software community to reuse encapsulated code units across a variety of software packages. Most comprehensive efforts at achieving inter-package modularity will quickly run afoul of a very practical problem, being able to cohesively build the modules. Writing and maintaining build systems has long been an issue for many scientific software packages that rely on compiled languages such as C/C++. The push for inter-package modularity compounds this issue by additionally requiring binary artifacts from disparate developers to interoperate at a binary level. Thankfully, the de facto build tool for C/C++, CMake, is more than capable of supporting the myriad of edge cases that complicate writing robust build systems. Unfortunately, writing and maintaining a robust CMake build system can be a laborious endeavor because CMake provides few abstractions to aid the developer. Further, the need to significantly simplify the process of writing robust CMake-based build systems, especially in inter-package builds, motivated us to write CMaize. In addition to describing the architecture and design of CMaize, the article also demonstrates how CMaize is used in production-level software.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Structural dynamics modeling of spent nuclear fuel during hypothetical package drop events

The response of spent nuclear fuel (SNF) to hypothetical package drop events is of particular interest in the scope of spent fuel storage and transportation because of the mechanical shock encountered in such scenarios. Previous testing and modeling by the U.S. Department of Energy has demonstrated that the shock and vibration environment of normal shipping and handling conditions (excluding package drop events) is relatively benign and does not challenge the integrity of spent nuclear fuel. Cask drop events are worth considering because SNF packages are required to withstand free drops onto unyielding surfaces as part of their licensing basis. The acceleration experienced during drop events can be orders of magnitude higher, and thus more advanced models are needed to encompass potential nonlinear behavior of the fuel, such as spacer grid buckling and rod-to-rod impact. This work describes a number of finite element models developed to calculate the response of spent nuclear fuel to various hypothetical drop events that have been validated by package and fuel assembly drop tests conducted in the last decade. Sensitivity of the model response to factors such as package drop orientation, secondary impacts, and irradiated material properties as well as their potential impacts to fuel cladding integrity, was also investigated. Cask drops are not expected as a regular occurrence during SNF transportation, but this work helps raise the understanding of SNF mechanical loads to the point of consistency with the package design requirements.

Kadooka, Kevin↗

Packages of Distributed Energy Technologies Demonstrating Demand Flexibility at Community Scale

The combination of increased electric load growth across all sectors, deferred electrical infrastructure investment, and other factors resulting in variable electric power supply, has created technical challenges to maintaining a resilient and reliable grid. Many federal, regional, and local efforts are in play to modernize the electric grid, including advancing building technologies and distributed energy resources (DERs) that are utilizing smarter controls to become responsive to both occupant and grid needs. This report reviews ten pilot projects demonstrating how groups of buildings combined with behind-the-meter (BTM) DERs such as electric vehicle (EV) charging, battery storage, flexible HVAC and domestic hot water systems, and photovoltaic systems can reliably and cost effectively provide grid services. Each of the ten pilot projects aim to deliver both energy efficiency and demand flexibility (DF) while supporting load growth. The ten demonstration teams are piloting flexible DER packages across diverse communities of residential and commercial buildings to address a variety of regional grid needs. The outcomes of these pilot projects will be used to inform future scaling through utility program development. This paper characterizes the ten teams, showcasing the decision-making process used by each group to develop their packages (Section 2), the grid services they plan to deliver (Section 3), the types of DER packages selected for deployment within building sectors (Section 4) and trends between building sector, DER types, and grid services In order to achieve community scale benefits, the pilot projects must utilize aggregated control mechanisms for coordinating buildings and DERs together. Several types of coordinated control architectures have evolved amongst the teams, influenced by use type, existing market conditions, and integration type. Three coordinated controls architectures have been characterized, highlighting their use cases, benefits, challenges, and tradeoffs in their design. These insights can aid utilities, control vendors, and developers in scaling community-level energy systems (Paul, 2024). Ultimately, the technology packages selected by the ten teams will be coordinated to provide power system services, also known as grid services. Insights from these demonstrations will be useful for grid operators, regulators, aggregators and other stakeholders as they look to deploy demand flexible resources as grid services in the future. The grid services that each team is targeting for demonstration are described in Section 3 and Section 4. Methods for evaluating the grid services have been described in the paper Metrics for Evaluating Grid Service Provision from Communities of Grid-interactive and Efficient Buildings and other DER (MacDonald, 2023). To identify technology packages for demonstration, Section 2 shows that project teams used a range of analysis approaches, including building energy modeling, AMI data analysis, cost-benefit frameworks, and utility pilot data. Some teams emphasized technical modeling to quantify grid impacts and demand reduction potential, while others prioritized economic evaluations, stakeholder input, or exploratory pilots to inform deployment decisions. This diversity reflects the need to tailor selection methods to project goals, available data, and organizational context. Section 5 discusses trends between the DER technologies deployed and the grid service provisions from each team. Residential buildings (multifamily and single family) lean towards technologies that enhance energy efficiency (e.g. weatherization upgrades, smart thermostats) and onsite power generation integration (e.g. solar PV). Commercial building demonstrations prioritize technologies that ensure operational reliability (e.g. battery storage) and centralized energy management systems and optimization solutions. Teams that are deploying controllable storage-based technologies are more likely to provide grid services that require a near real-time response. Teams incorporating load shifting technologies like smart thermostats with HEMs are likely to include energy markets participation and customer bill management offerings. Campus demonstrations are adopting diverse sets of DERs to emphasize renewable generation, paired with centralized control. This section also describes technologies that were considered during project planning but ultimately excluded from final deployment. These demonstrations reveal that effective DER package design should be tailored to building type, customer segment, and construction vintage. Multifamily buildings benefit from centralized HVAC upgrades and supervisory controls, while single-family homes are well-suited for individualized technologies like solar, storage, and smart home energy monitors. Commercial and campus settings prioritize EMIS integration and load optimization. New construction enables cost-effective integration of DER-ready infrastructure, whereas retrofits require deployments aligned with owner and tenant value streams. For utility program planners, early coordination with developers and building owners, paired with segmented and modular program offerings, can improve adoption, scalability, and grid impact.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Modeled Retrofit Package Performance for Schools

This report details modeled energy performance and savings from retrofit packages in prototypical school buildings in climate zones throughout the U.S. The information herein serves as a reference for elementary and secondary schools interested in implementing retrofit packages in their facilities for energy savings as well as health and safety benefits. School models developed for simulating package performance differentiated between rural and urban environments. Simulations were run for 10 distinct climate zones covering a range of climate conditions throughout the U.S. Results include savings estimates for electricity, natural gas, CO 2 emissions, and annual utility costs for nine different retrofit packages that combine energy conservation measures, including HVAC controls and equipment upgrades, lighting efficiency upgrades, and electrification technologies such as heat pumps for space conditioning and domestic hot water. Nine additional retrofit packages were also developed for elementary schools and modeled in two climate zones. Appendix B describes the additional retrofit packages and presents savings estimates.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Evaluation of Hydrogen Gas Generation and Permeation in the 9979 Type AF Shipping Package

The 9979 Type AF Shipping Packaging is a cost-effective radioactive material package designed by Savannah River National Laboratory (SRNL) that consists of two primary components: a foamed outer drum for structural protection and an inner containment drum. The packaging was designed to transport Highly Enriched Uranium (HEU), Low Enriched Uranium (LEU), and other isotopes not exceeding a Type A quantity. These contents have the potential to generate flammable hydrogen gas during transport due to the degradation of hydrogenous materials (e.g. water vapor, plastics, etc) by high-energy alpha radiation. Since 10 CFR 71.43(h) prohibits the incorporation of packaging features explicitly designed for continuous venting, alternative justification was required to demonstrate that the requirements of 10 CFR 71.43(d) for negligible reactions between packaging components and contents were satisfied. An analysis was performed to demonstrate that the potential for hydrogen gas generation over a one-year period was limited by the effects of permeation through the packaging materials. The rate of hydrogen collection was evaluated for both the inner containment drum and the outer structural drum under 10 CFR 71.71 Normal Conditions of Transport (NCT). The analysis concludes that the Lower Flammability Limit (LFL) for hydrogen gas will not be reached in a one-year shipping period assuming a minimum void volume is maintained within the drum.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Learning to Predict and Improve Build Successes in Package Ecosystems

Software has become increasingly complex, with a typical application depending on tens or hundreds of packages. Finding compatible versions and build configurations of these packages is challenging. This paper presents a method to learn the likelihood of software build success, and techniques for leveraging this information to guide dependency solvers to better software configurations. We leverage the heavily parameterized package recipes from the Spack package manager to produce a training data set of builds, and we use Graph Neural Networks to learn whether a given package configuration will build successfully or not. We apply our tool to the U.S. Exascale Computing Project’s software stack. We demonstrate its effectiveness in predicting whether a given package will build successfully. We show that our technique can be used to improve the solutions generated by dependency solvers, reducing the need for developers to find working builds by trial and error.

97 MATHEMATICS AND COMPUTING↗

On the stability and pointing of an attached double-gimbal experiment package

The pointing capability of a double gimbal experiment isolation and control system of the Apollo telescope mount (ATM) type was investigated. Three composite structural models of an experiment package connected through frictionless gimbals to a carrier vehicle (including a rigid package-rigid carrier model, a rigid package-flexible carrier model, and a flexible package-flexible carrier model) were used, and a linear model of the nominal ATM gimbal control system is considered. A linear stability analysis was performed to verify stability of the control system with nominal gains. Transform techniques were used to compute pointing errors onboard the experiment package due to random crew motions input into the carrier vehicle. Results of the investigation indicate that there is no stability problem due to flexible coupling of the experiment package and the carrier, and that the ATM-type system is capable of pointing accuracies better than 0.1 arc second.

Groom, N. J.↗

Apparatus and method for skin packaging articles

A system for skin packaging articles including a loading zone for positioning articles to be packaged upon a substrate, a thermoplastic film heating and vacuum operated skin packaging zone for covering the articles with film laminated to the substrate and a slitting zone for separating and trimming the individual skin packaged articles. The articles are passed to the successive zones. The loading zone may be adapted for conveyorized instead of hand loading. In some cases, where only transverse cutting of the film web is necessary, it may be desirable to eliminate the slitting zone and remove the skin packaged article or articles directly from the packaging zone. A conveniently located operating panel contains controls for effecting automatic, semiautomatic or manual operation of the entire system of any portions in any manner desired.

Madsen, B.↗

Reliability evaluation of hermetic dual in-line flat microcircuit packages

The relative strengths and weaknesses of 35 commonly used hermetic flat and dual in-line packages were determined and used to rank each of the packages according to a numerical weighting scheme for package attributes. The list of attributes included desirable features in five major areas: lead and lead seal, body construction, body materials, lid and lid seal, and marking. The metal flat pack and multilayer integral ceramic flat pack and DIP received the highest rankings, and the soft glass Cerdip and Cerpak types received the lowest rankings. Loss of package hermeticity due to lead and lid seal problems was found to be the predominant failure mode from the literature/data search. However, environmental test results showed that lead and lid seal failures due to thermal stressing was only a problem with the hard glass (Ceramic) body DIP utilizing a metal lid and/or bottom. Insufficient failure data were generated for the other package types tested to correlate test results with the package ranking.

Johnson, G. M.↗

Packaging for Food Service

Most of the key areas of concern in packaging the three principle food forms for the space station were covered. It can be generally concluded that there are no significant voids in packaging materials availability or in current packaging technology. However, it must also be concluded that the process by which packaging decisions are made for the space station feeding program will be very synergistic. Packaging selection will depend heavily on the preparation mechanics, the preferred presentation and the achievable disposal systems. It will be important that packaging be considered as an integral part of each decision as these systems are developed.

Stilwell, E. J.↗

Space station power semiconductor package

A package of high-power switching semiconductors for the space station have been designed and fabricated. The package includes a high-voltage (600 volts) high current (50 amps) NPN Fast Switching Power Transistor and a high-voltage (1200 volts), high-current (50 amps) Fast Recovery Diode. The package features an isolated collector for the transistors and an isolated anode for the diode. Beryllia is used as the isolation material resulting in a thermal resistance for both devices of .2 degrees per watt. Additional features include a hermetical seal for long life -- greater than 10 years in a space environment. Also, the package design resulted in a low electrical energy loss with the reduction of eddy currents, stray inductances, circuit inductance, and capacitance. The required package design and device parameters have been achieved. Test results for the transistor and diode utilizing the space station package is given.

Balodis, Vilnis↗