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At least 1,333 records · Page 74

Corrigendum to "Microstructural Characterization of Metal Foams: An Examination of the Applicability of the Theoretical Models for Modeling Foams"

Establishing the geometry of foam cells is useful in developing microstructure-based acoustic and structural models. Since experimental data on the geometry of the foam cells are limited, most modeling efforts use an idealized three-dimensional, space-filling Kelvin tetrakaidecahedron. The validity of this assumption is investigated in the present paper. Several FeCrAlY foams with relative densities varying between 3 and 15% and cells per mm (c.p.mm.) varying between 0.2 and 3.9 c.p.mm. were microstructurally evaluated. The number of edges per face for each foam specimen was counted by approximating the cell faces by regular polygons, where the number of cell faces measured varied between 207 and 745. The present observations revealed that 50-57% of the cell faces were pentagonal while 24-28% were quadrilateral and 15-22% were hexagonal. The present measurements are shown to be in excellent agreement with literature data. It is demonstrated that the Kelvin model, as well as other proposed theoretical models, cannot accurately describe the FeCrAlY foam cell structure. Instead, it is suggested that the ideal foam cell geometry consists of 11 faces with 3 quadrilateral, 6 pentagonal faces and 2 hexagonal faces consistent with the 3-6-2 Matzke cell

Raj. Sai V.↗

Quantitative Validation of the Integrated Medical Model (IMM) for ISS Missions

Lifetime Surveillance of Astronaut Health (LSAH) provided observed medical event data on 33 ISS and 111 STS person-missions for use in further improving and validating the Integrated Medical Model (IMM). Using only the crew characteristics from these observed missions, the newest development version, IMM v4.0, will simulate these missions to predict medical events and outcomes. Comparing IMM predictions to the actual observed medical event counts will provide external validation and identify areas of possible improvement. In an effort to improve the power of detecting differences in this validation study, the total over each program ISS and STS will serve as the main quantitative comparison objective, specifically the following parameters: total medical events (TME), probability of loss of crew life (LOCL), and probability of evacuation (EVAC). Scatter plots of observed versus median predicted TMEs (with error bars reflecting the simulation intervals) will graphically display comparisons while linear regression will serve as the statistical test of agreement. Two scatter plots will be analyzed 1) where each point reflects a mission and 2) where each point reflects a condition-specific total number of occurrences. The coefficient of determination (R2) resulting from a linear regression with no intercept bias (intercept fixed at zero) will serve as an overall metric of agreement between IMM and the real world system (RWS). In an effort to identify as many possible discrepancies as possible for further inspection, the -level for all statistical tests comparing IMM predictions to observed data will be set to 0.1. This less stringent criterion, along with the multiple testing being conducted, should detect all perceived differences including many false positive signals resulting from random variation. The results of these analyses will reveal areas of the model requiring adjustment to improve overall IMM output, which will thereby provide better decision support for mission critical applications.

validation↗

Optimal estimation of entanglement in optical qubit systems

We address the experimental determination of entanglement for systems made of a pair of polarization qubits. We exploit quantum estimation theory to derive optimal estimators, which are then implemented to achieve ultimate bound to precision. In particular, we present a set of experiments aimed at measuring the amount of entanglement for states belonging to different families of pure and mixed two-qubit two-photon states. Our scheme is based on visibility measurements of quantum correlations and achieves the ultimate precision allowed by quantum mechanics in the limit of Poissonian distribution of coincidence counts. Although optimal estimation of entanglement does not require the full tomography of the states we have also performed state reconstruction using two different sets of tomographic projectors and explicitly shown that they provide a less precise determination of entanglement. The use of optimal estimators also allows us to compare and statistically assess the different noise models used to describe decoherence effects occurring in the generation of entanglement.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

The SRG/eROSITA All-Sky Survey: Constraints on the structure growth from cluster number counts

Recent advancements in methods used in wide-area surveys have demonstrated the reliability of the number density of galaxy clusters as a viable tool for precision cosmology. Beyond testing the current cosmological paradigm, cluster number counts can also be used to investigate the discrepancies currently affecting cosmological measurements. In particular, cosmological studies based on cosmic shear and other large-scale structure probes routinely find a value for the amplitude of the fluctuations in the universe S​ 8 = σ 8 (Ω m /0.3) 0.5 smaller than the one inferred from the primary cosmic microwave background. In this work, we investigate this tension by measuring structure evolution across cosmic time as probed by the number counts of massive halos with the first SRG/eROSITA All-Sky Survey cluster catalog in the western Galactic hemisphere, complemented with the overlapping Dark Energy Survey Year-3, Kilo-Degree Survey, and Hyper Suprime-Cam data for weak lensing mass calibration, by implementing two different parameterizations and a model-agnostic method. In the first model, we measured the cosmic linear growth index as γ = 1.19 ± 0.21, which is in tension with the standard value of γ = 0.55 but in good statistical agreement with other large-scale structure probes. The second model is a phenomenological scenario in which we rescale the linear matter power spectrum at low redshift to investigate a potential reduction of structure formation, and it provided similar results. Finally, in a third strategy, we considered a standard ΛCDM cosmology, but we separated the cluster catalog into five redshift bins, measuring the cosmological parameters in each and inferring the evolution of the structure formation, finding hints of a reduction. Interestingly, the S ​8 value inferred from the number counts of the cluster eRASS1 when we add a degree of freedom to the matter power spectrum recovers the value inferred by cosmic shear studies. The observed reduction in the growth rate or systematic uncertainties associated with various measurements may account for the discrepancy in the S 8 ​ values suggested between cosmic shear probes and eROSITA cluster number counts and Planck CMB measurements.

cosmological parameters↗

Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension

A novel class of selective inhibitors of ROCK1 and ROCK2 has been identified by structural based drug design. PK/PD experiments using a set of highly selective Rho kinase inhibitors suggest that systemic Rho kinase inhibition is linked to a reversible reduction in lymphocyte counts. These results led to the consideration of topical delivery of these molecules, and to the identification of a lead molecule 7 which shows promising PK and PD in a murine model of pulmonary hypertension after intra-tracheal dosing.

59 BASIC BIOLOGICAL SCIENCES↗

A gain series method for accurate EMCCD calibration

Abstract Calibration of the gain and digital conversion factor of an EMCCD is necessary for accurate photon counting. We present a new method to quickly calibrate multiple gain settings of an EMCCD camera. Acquiring gain-series calibration data and analyzing the resulting images with the EMCCD noise model more accurately estimates the gain response of the camera. Furthermore, we develop a method to compare the results from different calibration approaches. Gain-series calibration outperforms all other methods in this self-consistency test.

36 MATERIALS SCIENCE↗

Response of LaBr{sub 3}(Ce) scintillators to 2.5 MeV fusion neutrons

Measurements of the response of LaBr{sub 3}(Ce) to 2.5 MeV neutrons have been carried out at the Frascati Neutron Generator and at tokamak facilities with deuterium plasmas. The observed spectrum has been interpreted by means of a Monte Carlo model. It is found that the main contributor to the measured response is neutron inelastic scattering on {sup 79}Br, {sup 81}Br, and {sup 139}La. An extrapolation of the count rate response to 14 MeV neutrons from deuterium-tritium plasmas is also presented. The results are of relevance for the design of γ-ray diagnostics of fusion burning plasmas.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Extremely bright submillimeter galaxies beyond the Lupus-I star-forming region

We report detections of two candidate distant submillimeter galaxies (SMGs), MM J154506.4−344318 and MM J154132.7−350320, which are discovered in the AzTEC/ASTE 1.1 mm survey toward the Lupus-I star-forming region. The two objects have 1.1 mm flux densities of 43.9 and 27.1 mJy, and have Herschel/SPIRE counterparts as well. The Submillimeter Array counterpart to the former SMG is identified at 890 μm and 1.3 mm. Photometric redshift estimates using all available data from the mid-infrared to the radio suggest that the redshifts of the two SMGs are z{sub photo}≃4–5 and 3, respectively. Near-infrared objects are found very close to the SMGs and they are consistent with low-z ellipticals, suggesting that the high apparent luminosities can be attributed to gravitational magnification. The cumulative number counts at S{sub 1.1mm}⩾25 mJy, combined with the other two 1.1 mm brightest sources, are 0.70{sub −0.34}{sup +0.56} deg{sup −2}, which is consistent with a model prediction that accounts for flux magnification due to strong gravitational lensing. Unexpectedly, a z>3 SMG and a Galactic dense starless core (e.g., a first hydrostatic core) could be similar in the mid-infrared to millimeter spectral energy distributions and spatial structures at least at ≳1′′. This indicates that it is necessary to distinguish the two possibilities by means of broadband photometry from the optical to centimeter and spectroscopy to determine the redshift, when a compact object is identified toward Galactic star-forming regions.

79 ASTRONOMY AND ASTROPHYSICS↗

An Empirical Roofline Methodology for Quantitatively Assessing Performance Portability

System and node architectures continue to diversify to better balance on-node computation, memory capacity, memory bandwidth, interconnect bandwidth, power, and cost for specific computational workloads. For many application developers, achieving performance portability (effectively exploiting the capabilities of multiple architectures) is a desired goal. Unfortunately, dramatically different per-node performance coupled with differences in machine balance can lead to developers being unable to determine whether they have attained performance portability or simply written portable code. The Roofline model provides a means of quantitatively assessing how well a given application makes use of a target platform’s computational capabilities. In this paper, we extend the Roofline model so that it 1) empirically captures a more realistic set of performance bounds for CPUs and GPUs, 2) factors in the true cost of different floating-point instructions when counting FLOPs, 3) incorporates the effects of different memory access patterns, and 4) with appropriate pairing of code performance and Roofline ceiling, facilitates the performance portability analysis.

Computer Science↗

FutureGen2 Petrel Project

This Petrel project features geomechanical models that takes advantage of existing modeling work from PNNL and expands upon its framework to included overlying and underlying geologic zones. Where available, geomechanical logs were incorporated into these models. While the existing CO2 storage interval and caprock (Mt. Simon Ss and Eau Claire Shale) were finely layered by PNNL, the overlying layers were more coarsely layered to limit cell count.

FutureGen2↗

A spectroscopic study of the high excitation nebula NGC 6302

The wonderfully intricate irregular gaseous nebula NGC 6302 shows a great range of excitation from the S I to Fe VII forbidden lines. Data obtained with the International Ultraviolet Explorer (IUE) covering the spectral range of wavelengths 1200-3203 and with the image-photon counting system at the Anglo-Australian telescope emphasizing the region of wavelengths 3200-4880 are used for a new determination of the chemical composition of this object. No simple theoretical model can represent the observed intensities. Helium and nitrogen are enhanced in abundance, as noted by previous observers, but the enrichment of nitrogen is a whole order of magnitude. Carbon and oxygen are decreased in abundance, neon and heavier elements show a 'normal' abundance pattern, but calcium and possibly silicon are depleted; presumably they are concentrated in grains.

Aller, L. H.↗

Calibration of the active radiation detector for Spacelab-One

The flight models of the active radiation detector (ARD) for the ENV-01 environmental monitor were calibrated using gamma radiation. Measured sensitivities of the ion chambers were 6.1 + or - 0.3 micron rad per count for ARD S/N1, and 10.4 + or - 0.5 micron rad per count for ARD S/N2. Both were linear over the measured range 0.10 to 500 m/rad hour. The particle counters (proportional counters) were set to respond to approximately 85% of minimum ionizing particles of unit charge passing through them. These counters were also calibrated in the gamma field.

Source record↗

XSPEC: An x ray spectral fitting package. Version 2 of the user's guide

The user guide for XSPEC, a command driven, interactive, X-ray spectral fitting program is presented. It is designed to be completely detector independent so it can be used for any X-ray spectral instrument. An overview of the program commands and a walk through of an XSPEC session is presented. Individual commands and descriptions of the spectral models are given. For the more experienced user details of some of the programs associated with XSPEC, the command parser, and the addition of models to XSPEC are included. The PLT plotting package used by XSPEC is described together with the maximum likelihood option for users possessing X-ray spectra with small numbers of counts per bin. Details on the various files used by XSPEC and on the general file structure are also given.

Shafer, R. A.↗

Effects of Modeled Microgravity on Expression Profiles of Micro RNA in Human Lymphoblastoid Cells

Among space radiation and other environmental factors, microgravity or an altered gravity is undoubtedly the most significant stress experienced by living organisms during flight. In comparison to the static 1g, microgravity has been shown to alter global gene expression patterns and protein levels in cultured cells or animals. Micro RNA (miRNA) has recently emerged as an important regulator of gene expression, possibly regulating as many as one-third of all human genes. miRNA represents a class of single-stranded noncoding regulatory RNA molecules (~ 22 nt) that control gene expressions by inhibiting the translation of mRNA to proteins. However, very little is known on the effect of altered gravity on miRNA expression. We hypothesized that the miRNA expression profile will be altered in zero gravity resulting in regulation of the gene expression and functional changes of the cells. To test this hypothesis, we cultured TK6 human lymphoblastoid cells in Synthecon s Rotary cell culture system (bioreactors) for 72 h either in the rotating (10 rpm) to model the microgravity in space or in the static condition. The cell viability was determined before and after culturing the cells in the bioreactor using both trypan blue and guava via count. Expressions of a panel of 352 human miRNA were analyzed using the miRNA PCRarray. Out of 352 miRNAs, expressions of 75 were significantly altered by a change of greater than 1.5 folds and seven miRNAs were altered by a fold change greater than 2 under the rotating culture condition. Among these seven, miR-545 and miR-517a were down regulated by 2 folds, whereas miR-150, miR-302a, miR-139-3p, miR-515-3p and miR-564 were up regulated by 2 to 8 folds. To confirm whether this altered miRNA expression correlates with gene expression and functional changes of the cells, we performed DNA Illumina Microarray Analysis and validated the related genes using q-RT PCR.

Mangala, Lingegowda S.↗

A Statistical Model of Tropical Cyclone Tracks in the Western North Pacific with ENSO-Dependent Cyclogenesis

A new statistical model for western North Pacific Ocean tropical cyclone genesis and tracks is developed and applied to estimate regionally resolved tropical cyclone landfall rates along the coasts of the Asian mainland, Japan, and the Philippines. The model is constructed on International Best Track Archive for Climate Stewardship (IBTrACS) 1945-2007 historical data for the western North Pacific. The model is evaluated in several ways, including comparing the stochastic spread in simulated landfall rates with historic landfall rates. Although certain biases have been detected, overall the model performs well on the diagnostic tests, for example, reproducing well the geographic distribution of landfall rates. Western North Pacific cyclogenesis is influenced by El Nino-Southern Oscillation (ENSO). This dependence is incorporated in the model s genesis component to project the ENSO-genesis dependence onto landfall rates. There is a pronounced shift southeastward in cyclogenesis and a small but significant reduction in basinwide annual counts with increasing ENSO index value. On almost all regions of coast, landfall rates are significantly higher in a negative ENSO state (La Nina).

Yonekura, Emmi↗

Performance Evaluation of Large Aperture 'Polished Panel' Optical Receivers Based on Experimental Data

Recent interest in hybrid RF/Optical communications has led to the development and installation of a "polished-panel" optical receiver evaluation assembly on the 34-meter research antenna at Deep-Space Station 13 (DSS-13) at NASA's Goldstone Communications Complex. The test setup consists of a custom aluminum panel polished to optical smoothness, and a large-sensor CCD camera designed to image the point-spread function (PSF) generated by the polished aluminum panel. Extensive data has been obtained via realtime tracking and imaging of planets and stars at DSS-13. Both "on-source" and "off-source" data were recorded at various elevations, enabling the development of realistic simulations and analytic models to help determine the performance of future deep-space communications systems operating with on-off keying (OOK) or pulse-position-modulated (PPM) signaling formats with photon-counting detection, and compared with the ultimate quantum bound on detection performance for these modulations. Experimentally determined PSFs were scaled to provide realistic signal-distributions across a photon-counting detector array when a pulse is received, and uncoded as well as block-coded performance analyzed and evaluated for a well-known class of block codes.

on-off keying (OOK)↗

Estimating Highway Volumes Using Vehicle Probe Data - Proof of Concept: Preprint

This paper examines the feasibility of using sampled commercial probe data in combination with validated continuous counter data to accurately estimate vehicle volume across the entire roadway network, for any hour during the year. Currently either real time or archived volume data for roadways at specific times are extremely sparse. Most volume data are average annual daily traffic (AADT) measures derived from the Highway Performance Monitoring System (HPMS). Although methods to factor the AADT to hourly averages for typical day of week exist, actual volume data is limited to a sparse collection of locations in which volumes are continuously recorded. This paper explores the use of commercial probe data to generate accurate volume measures that span the highway network providing ubiquitous coverage in space, and specific point-in-time measures for a specific date and time. The paper examines the need for the data, fundamental accuracy limitations based on a basic statistical model that take into account the sampling nature of probe data, and early results from a proof of concept exercise revealing the potential of probe type data calibrated with public continuous count data to meet end user expectations in terms of accuracy of volume estimates.

25 ENERGY STORAGE↗