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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,531 records · Page 85
All sourcesNASA NTRSDOE OSTI
DOE OSTI2023

Hardware-in-the-Loop Evaluation of Grid-Edge DER Chip Integration Into Next-Generation Smart Meters: Preprint

To facilitate the implementation of distributed energy resource management systems (DERMS), we propose to insert a grid-edge distributed energy resource (DER) chip hosting a DERMS algorithm into the next generation of smart meters. This will create a pathway for the wide adoption of DERMS technology because many utilities plan to invest in advanced metering infrastructure in the near future. This will also bridge the gap between an electrical power utility and DERs behind the meter. The DER chip is designed to follow power direction signals from the DERMS coordinator while balancing its local objectives. We tested the chip using a controller- and power-hardware-in-the-loop evaluation under three scenarios that a DERMS could face in the real world. The DER chip was capable of and effective at directing four heterogeneous DERs to respond to a DERMS coordinator for grid services (e.g., voltage regulation and a virtual power plant).

distributed energy resource management system↗
DOE OSTI2020

PcsR2 Is a LuxR-Type Regulator That Is Upregulated on Wheat Roots and Is Unique to Pseudomonas chlororaphis

LuxR solos are common in plant-associated bacteria and increasingly recognized for playing important roles in plant-microbe interkingdom signaling. Unlike the LuxR-type transcriptional regulators of prototype LuxR/LuxI quorum sensing systems, luxR solos do not have a LuxI-type autoinducer synthase gene associated with them. LuxR solos in plant-pathogenic bacteria are important for virulence and in plant endosymbionts contribute to symbiosis. In the present study, we characterized an atypical LuxR solo, PcsR2, in the biological control species Pseudomonas chlororaphis 30–84 that is highly conserved among sequenced P. chlororaphis strains. Unlike most LuxR solos in the plant-associated bacteria characterized to date, pcsR2 is not associated with a proline iminopeptidase gene and the protein has an atypical N-terminal binding domain. We created a pcsR2 deletion mutant and used quantitative RT-PCR to show that the expression of pcsR2 and genes in the operon immediately downstream was upregulated ~10-fold when the wild type strain was grown on wheat roots compared to planktonic culture. PcsR2 was involved in upregulation. Using a GFP transcriptional reporter, we found that expression of pcsR2 responded specifically to root-derived substrates as compared to leaf-derived substrates but not to endogenous AHLs. Compared to the wild type, the mutant was impaired in the ability to utilize root carbon and nitrogen sources in wheat root macerate and to colonize wheat roots. Phenazine production and most biofilm traits previously shown to be correlated with phenazine production also were diminished in the mutant. Gene expression of several of the proteins in the phenazine regulatory network including PhzR, Pip (phenazine inducing protein) and RpeA/RpeB were reduced in the mutant, and overexpression of these genes in trans restored phenazine production in the mutant to wild-type levels, indicating PcsR2 affects the activity of the these regulatory genes upstream of RpeA/RpeB via an undetermined mechanism. Our results indicate PcsR2 upregulates the expression of the adjacent operon in response to unknown wheat root-derived signals and belongs to a novel subfamily of LuxR-type transcriptional regulators found in sequenced P. chlororaphis strains.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2015

Data center cooling method

A method aspect for removing heat from a data center may use liquid coolant cooled without vapor compression refrigeration on a liquid cooled information technology equipment rack. The method may also include regulating liquid coolant flow to the data center through a range of liquid coolant flow values with a controller-apparatus based upon information technology equipment temperature threshold of the data center.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
DOE OSTI2019

Planning for Failure: End-of-Life Strategies for HVAC Systems

In the United States, there are several existing and pending regulations for refrigerant management, and the range and complexity of these regulations make it difficult for engineers, contractors, and building owners to keep up with all the requirements, and they introduce confusion and uncertainty in the market. This article explores these issues to help describe a path forward for HVAC&R equipment waste.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
DOE OSTI2019

Isocitrate dehydrogenase gene mutations and 2-hydroxyglutarate accumulation in esophageal squamous cell carcinoma

Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are key metabolic enzymes that convert isocitrate to α-ketoglutarate. Somatic point mutations in IDH1/2 confer a gain-of-function in cancer cells, resulting in overproduction of an oncometabolite, 2-hydroxyglutarate (2HG). 2HG interferes with cellular metabolism and epigenetic regulation, contributing to oncogenesis. Given that IDH1 and IDH2 are attracting attention as promising therapeutic targets, better evaluation of the incidence of IDH1 and IDH2 mutations and 2HG level in human cancers is clinically important. This is the first study to assess their incidence in esophageal squamous cell carcinomas (ESCCs). First, we established pyrosequencing assays for IDH1 and IDH2 mutations and revealed that these mutations were absent in 10 ESCC cell lines and 96 ESCC tissues. Second, utilizing IDH1 and IDH2 overexpression vectors, we demonstrated that LC-MS/MS assays can accurately evaluate 2HG level and found that some ESCC cases presented a high level of 2HG. In conclusion, IDH1 or IDH2 mutations play a limited role in the development of ESCC. 2HG is potentially synthesized to high levels in the absence of IDH1 and IDH2 mutations, and this may correlate with progression of ESCCs.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2022

Empower Wall: Active insulation system leveraging additive manufacturing and model predictive control

Buildings are one of the largest energy consumers worldwide, using large amounts of energy during their construction and for climate control during operation. Active insulation systems (AIS) have been shown to reduce the energy needed for climate control in buildings by dynamically regulating the heat transferred between a building’s interior and exterior. Infrastructure-scale additive manufacturing (AM) has the potential to reduce the resources needed for building construction. Combining these two technologies into a single building envelope would create a path towards more sustainable buildings. A test was conducted for the Federal Energy Management Program (FEMP) Energy Exchange training and trade show, in August 2021, to investigate a new building envelope design, termed the Empower Wall, that utilized an AIS and was constructed using AM. Model predictive control was implemented to manage operation of the Empower Wall in concert with the existing HVAC system. Finally, the prototype system demonstrated that the Empower Wall lowered total energy consumption and reduced the cost of energy used.

36 MATERIALS SCIENCE↗
DOE OSTI2023

Medium-Voltage Isolated Auxiliary Power Supply Design for High Insulation Capability, Ultra-Low Coupling Capacitance, and Small Size

To fully utilize the benefits of medium-voltage (MV) silicon carbide (SiC)-based converter and achieve high power density, the isolated auxiliary power supply (IAPS) needs to be as small as possible. However, the high insulation and low coupling capacitance requirements, considering the high voltage and high dv / dt , are constraints of size reduction. This article proposes an MV IAPS design for high insulation capability, ultra-low coupling capacitance, and small size. The topology selection, efficiency, load regulation, coupling capacitance, and size reduction considerations are discussed. A 2.5 W MV IAPS is designed and built for a 10 kV SiC mosfet -based 13.8 kV/100 kW three-phase converter, achieving a partial discharge (PD) inception voltage of higher than 15 kV rms, ultra-low coupling capacitance of 1.03 pF, and smaller size than that of the commercial products as well as the state-of-art research prototypes. Experimental results of PD test, 10 kV SiC mosfet -based half-bridge test, and 13.8 kV/100 kVA three-phase converter full rating test are conducted for design validation.

42 ENGINEERING↗
DOE OSTI2022

Neutron Source Facility of the National Science Center “Kharkiv Institute of Physics and Technology” at Kharkiv, Ukraine

Argonne National Laboratory developed, designed, and supported the construction of a state-of-the-art Neutron Source Facility (NSF) at the Kharkov Institute of Physics and Technology (KIPT) in Kharkov Ukraine, under the U.S. DOE NNSA Russian Research Reactor Fuel Return (RRRFR) program. Ukraine approved the return of all highly enriched uranium in the country to Russia prior to the 2012 Nuclear Security Summit in return for the RRRFR program to fund the development, the design, and the construction of the NSF. The facility is designed to produce medical isotopes, train nuclear professionals, support the Ukrainian nuclear industry, and provide experimental capabilities for performing reactor physics, materials, and basic science research. The NSF was successfully started and operated in August 2021. The NSF is the first facility of this type in the world, and it will be used to understand the physics of driven systems for energy production and the disposal of spent nuclear fuels. The NSF consists of a subcritical assembly using low enriched uranium (LEU) fuel driven with an electron accelerator. The NSF target design utilizes tungsten or natural uranium for producing neutrons through photonuclear reactions using 100-MeV electrons. The accelerator power is 100 KW, which produces 3x10 14 neutrons per second from the uranium target. The subcritical assembly is designed to obtain the highest possible neutron flux intensity with an effective neutron multiplication factor of less than 0.98. Passive safety, reliability, and environmental considerations were included in the NSF design. The NSF utilization study shows that this neutron source has the capability of producing different medical isotopes. Several horizontal neutron channels are incorporated for performing applied and basic research. The NSF is configured to accommodate future design upgrades and new missions. The facility design was approved by the Ukraine Academy of Sciences before starting the NSF construction. The construction, the equipment installation, and the operation of the different systems of the NSF were completed and approved by the Ukrainian regulators. In July 2020, the State Nuclear Regulatory Inspectorate of Ukraine (SNRIU) issued a license for the physical startup of the NSF. The construction of facility was completed in early 2021.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗
NASA NTRS2023

A Summary of Structural Test and Simulation Results for Hawker 4000 Composite Fuselage Hardware

NASA Langley Research Center (LaRC) was able to obtain a partially fabricated Hawker Beechcraft Model 4000 (Hawker 4000) aft aircraft section to use for study. The Hawker 4000 is a medium sized business jet (14 Code of Federal Regulations Part 25 – Transport Category Aircraft) with seating for 8 to 14 people and fabricated out of carbon composite. The Hawker 4000 was designed in the early 2000s to compete with Gulfstream and Bombardier business jet units. The Hawker Beechcraft business unit declared bankruptcy in 2012, and abruptly halted production of the 4000 series aircraft. As a result, only 73 full production aircraft were built. This all-composite aft fuselage section was an ideal candidate to utilize for investigations of composite structures undergoing dynamic loading in order to satisfy NASA Revolutionary Vertical Lift Technology (RVLT) project objectives. Thus, a team at NASA LaRC embarked on a test and simulation program in late 2021 in order to generate test data of composite structures undergoing dynamic loading conditions. As a part of these investigations, methods including reverse engineering the geometry, conducting as-fabricated materials testing and using non-destructive evaluation (NDE) techniques such as ultrasonic through transmission were utilized in order to develop digital twin finite element models for use in computational simulations.

dynamic composite testing↗
DOE OSTI2015

Anticipating Change - A Means to Save Time and Rethink the Implementation of the 10 Code of Federal Regulations 770 Real Property Transfer Process - 15662

The Department of Energy (DOE) issued 10 Code of Federal Regulations (CFR) 770 in 2000 for the 'Transfer of Real Property at Defense Nuclear Facilities for Economic Development'. The rule was issued in order to 'offset negative impacts on communities caused by unemployment from related DOE down-sizing, facility close-outs and workforce restructuring'. There is a sense of urgency implied in efforts designed to address economic conditions, especially in communities that have hosted DOE facilities and are experiencing negative impacts of mission changes. Despite the urgency, the transfer of real property from DOE or any federal agency is a lengthy, complex, iterative, but necessarily diligent effort. After all, the aim of the process is to be able to demonstrate that the property proposed for transfer is protective of human health and the environment for the intended use. Notwithstanding the efforts of the economic development organization to market, recruit, and prepare a robust proposal to request property, and the efforts of DOE to perform the many due diligence activities in response to that request, the actual results of the evaluations are an unknown until a major portion of the process is completed. Will the property be determined to be suitable for transfer? Will there be deed restrictions? Is indemnification available? Has a mission need for the property arisen while working through the reviews? There are many points along the way that can sidetrack or delay progress and, in the interim, the economic viability of the proposal can collapse. Even without the unforeseen events, the process in and of itself is lengthy. It is often heard (loudly) that it takes far too long to obtain a piece of property once a request is made; that observation/criticism is worthy of serious attention. Rather than revisit old debates, why not learn from them? Why not look at the transfer process from a different point of view and ameliorate it so it can be more responsive to community needs? Why not anticipate change, anticipate requests, and make property available before a request as well as responding to requests to make property available? There are several ways to rethink and modify the way the transfer process is implemented to reduce the time following a request. The modifications would arise from both internal information sharing, integrated and timely up-front planning and, in particular, by varying how and when certain elements of the process to enable transfer are performed. This paper will address: 1. How a unified overall vision can be created from the cleanup input of Site-Specific Advisory Boards with the Community Reuse Organizations' planning for economic development and can help inform site cleanup to end state to future use; 2. Why DOE is in the best position to know its site conditions and could determine ahead of a transfer request what property is indeed available and notify of that determination; 3. How a range of disposition paths for real property are available to DOE; and 4. Why broadening the understanding of 'best interest of the government' to one that is clearly able to recognize non-monetary benefits is in the best interest of the government. Anticipating change helps prepare DOE and their host communities for the future. It creates opportunities for flexibility and time savings. The sooner DOE's unneeded and under-utilized real property can be made available to the communities that need it most, the sooner those communities can work to moderate the adverse effects of DOE mission changes. (author)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
DOE OSTI2024

Engineering Ultrathin Alloy Shell in Au@AuPd Core-Shell Nanoparticles for Efficient Plasmon-Driven Photocatalysis

Bimetallic core-shell nanoparticles (NPs) possessing a synergetic coupling of plasmonic and catalytic metals have emerged as promising prototypes for efficient plasmon-driven photocatalysis. Here, Au@AuPd core-shell NPs composed of Au core NP and ultrathin AuPd shell are introduced to acquire improved light utilization efficiency in photocatalytic selective oxidation. With systematical control of the composition of the ultrathin alloy shell, it reveals that the Au@AuPd core-shell NPs with 10 at% Pd (in the single-atom alloy regime) is an effective nanostructure capable of maximizing the quantum yield of plasmon-induced light absorption and optimizing the surface electronic structure for catalytic reactions. This controlled system provides new insights into shell engineering for enhancing photocatalytic performance via the regulation of energy funneling processes in core-shell nanocatalysts.

36 MATERIALS SCIENCE↗
DOE OSTI2013

Flex Fuel Optimized SI and HCCI Engine

The central objective of the proposed work is to demonstrate an HCCI (homogeneous charge compression ignition) capable SI (spark ignited) engine that is capable of fast and smooth mode transition between SI and HCCI combustion modes. The model-based control technique was used to develop and validate the proposed control strategy for the fast and smooth combustion mode transition based upon the developed control-oriented engine; and an HCCI capable SI engine was designed and constructed using production ready two-step valve-train with electrical variable valve timing actuating system. Finally, smooth combustion mode transition was demonstrated on a metal engine within eight engine cycles. The Chrysler turbocharged 2.0L I4 direct injection engine was selected as the base engine for the project and the engine was modified to fit the two-step valve with electrical variable valve timing actuating system. To develop the model-based control strategy for stable HCCI combustion and smooth combustion mode transition between SI and HCCI combustion, a control-oriented real-time engine model was developed and implemented into the MSU HIL (hardware-in-the-loop) simulation environment. The developed model was used to study the engine actuating system requirement for the smooth and fast combustion mode transition and to develop the proposed mode transition control strategy. Finally, a single cylinder optical engine was designed and fabricated for studying the HCCI combustion characteristics. Optical engine combustion tests were conducted in both SI and HCCI combustion modes and the test results were used to calibrate the developed control-oriented engine model. Intensive GT-Power simulations were conducted to determine the optimal valve lift (high and low) and the cam phasing range. Delphi was selected to be the supplier for the two-step valve-train and Denso to be the electrical variable valve timing system supplier. A test bench was constructed to develop control strategies for the electrical variable valve timing (VVT) actuating system and satisfactory electrical VVT responses were obtained. Target engine control system was designed and fabricated at MSU for both single-cylinder optical and multi-cylinder metal engines. Finally, the developed control-oriented engine model was successfully implemented into the HIL simulation environment. The Chrysler 2.0L I4 DI engine was modified to fit the two-step vale with electrical variable valve timing actuating system. A used prototype engine was used as the base engine and the cylinder head was modified for the two-step valve with electrical VVT actuating system. Engine validation tests indicated that cylinder #3 has very high blow-by and it cannot be reduced with new pistons and rings. Due to the time constraint, it was decided to convert the four-cylinder engine into a single cylinder engine by blocking both intake and exhaust ports of the unused cylinders. The model-based combustion mode transition control algorithm was developed in the MSU HIL simulation environment and the Simulink based control strategy was implemented into the target engine controller. With both single-cylinder metal engine and control strategy ready, stable HCCI combustion was achived with COV of 2.1% Motoring tests were conducted to validate the actuator transient operations including valve lift, electrical variable valve timing, electronic throttle, multiple spark and injection controls. After the actuator operations were confirmed, 15-cycle smooth combustion mode transition from SI to HCCI combustion was achieved; and fast 8-cycle smooth combustion mode transition followed. With a fast electrical variable valve timing actuator, the number of engine cycles required for mode transition can be reduced down to five. It was also found that the combustion mode transition is sensitive to the charge air and engine coolant temperatures and regulating the corresponding temperatures to the target levels during the combustion mode transition is the key for a smooth combustion mode transition. As a summary, the proposed combustion mode transition strategy using the hybrid combustion mode that starts with the SI combustion and ends with the HCCI combustion was experimentally validated on a metal engine. The proposed model-based control approach made it possible to complete the SI-HCCI combustion mode transition within eight engine cycles utilizing the well controlled hybrid combustion mode. Without intensive control-oriented engine modeling and HIL simulation study of using the hybrid combustion mode during the mode transition, it would be impossible to validate the proposed combustion mode transition strategy in a very short period.

33 ADVANCED PROPULSION SYSTEMS↗
DOE OSTI2014

Structural Code Considerations for Solar Rooftop Installations

Residential rooftop solar panel installations are limited in part by the high cost of structural related code requirements for field installation. Permitting solar installations is difficult because there is a belief among residential permitting authorities that typical residential rooftops may be structurally inadequate to support the additional load associated with a photovoltaic (PV) solar installation. Typical engineering methods utilized to calculate stresses on a roof structure involve simplifying assumptions that render a complex non-linear structure to a basic determinate beam. This method of analysis neglects the composite action of the entire roof structure, yielding a conservative analysis based on a rafter or top chord of a truss. Consequently, the analysis can result in an overly conservative structural analysis. A literature review was conducted to gain a better understanding of the conservative nature of the regulations and codes governing residential construction and the associated structural system calculations.

Dwyer, Stephen F.↗
DOE OSTI2024

Safety Review of the Hydrogen Components of a Reference Design of the Wind-H2-Green Steel/Ammonia Project

The Department of Energy Hydrogen Fuel Cell Technology Office and Wind Energy Technologies Office's Wind-H2-Green Steel/Ammonia project is an initiative to demonstrate the feasibility and efficacy of GW-scale integrated energy systems. The team designed reference facilities that utilize wind- and solar-produced hydrogen for industrial steel and ammonia production. This novel concept warranted review of safety codes and standards as they apply to the designs and the identification of codes and standards gaps. This report reviews hydrogen production and storage codes and standards using reference design specifications from a Minnesota steel plant. Requirements, recommendations, and exclusions for the system were identified. Observed gaps included non-specific salt cavern storage requirements, electrolyzer capacity beyond regulated ranges, and lack of requirements for iron reduction via hydrogen. This report will aide future project design efforts and may provide a basis for safety reviews in new designs for industrial facilities with hydrogen production integration.

08 HYDROGEN↗
DOE OSTI2022

Precursor Analysis Report: Remote Access Attack on Oldsmar Water Treatment Facility 2021

The Remote Access Attack on Oldsmar Water Treatment Facility 2021 Precursor Analysis Report leverages publicly available information about the Oldsmar cyber attack and catalogs anomalous observables for each technique employed in the attack. This analysis is based upon the methodology of the Cybersecurity for the Operational Technology Environment (CyOTE) program. On 5 February 2021, an adversary gained unauthorized remote access to Bruce T. Haddock Water Treatment Plant in Oldsmar, Florida, which provides treated water to 15,000 customers. The adversary accessed the facility’s Supervisory Control and Data Acquisition (SCADA) workstation and human machine interface (HMI) to change the chemical concentration of sodium hydroxide, commonly referred to as lye and used to regulate acidity levels, from 100 parts per million (PPM) to 11,100 PPM. The chemical was raised to lethal levels that if ingested could lead to serious soft tissue damage, burns, or even death. The facility, however, had redundancies and alarms in place to alert personnel of dangerous chemical levels, and facility officials stated it would have taken 24 to 36 hours for the chemical changes to affect the water supply. Researchers and analysts identified six unique techniques utilized during the attack with a total of 23 observables using MITRE ATT&CK® for Industrial Control Systems. The CyOTE program assesses observables accompanying techniques used prior to the triggering event to identify opportunities to detect malicious activity. If observables accompanying the attack techniques are perceived and investigated prior to the triggering event, earlier comprehension of malicious activity can take place. Four of the identified techniques used during the Oldsmar cyber attack were precursors to the triggering event. Analysis identified 21 observables associated with these precursor techniques, 20 of which were assessed to have an increased likelihood of being perceived in the minutes preceding the triggering event. The response and comprehension time could have been reduced if the observables had been identified earlier. The information gathered in this report contributes to a library of observables tied to a repository of artifacts, data sources, and technique detection references for practitioners and developers to support the comprehension of indicators of attack. Asset owners and operators can use these products if they experience similar observables or to prepare for comparable scenarios.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗
DOE OSTI2017

Multi-time scale control of demand flexibility in smart distribution networks

This study presents a multi-timescale control strategy to deploy demand flexibilities of electric vehicles (EV) for providing system balancing and local congestion management by simultaneously ensuring economic benefits to participating actors. First, the EV charging problem from consumer, aggregator, and grid operator’s perspective is investigated. A hierarchical control architecture (HCA) comprising scheduling, coordinative, and adaptive layers is then designed to realize their coordinative goal. This is realized by integrating a multi-time scale control, which works from a day-ahead scheduling up to real-time adaptive control. The performance of the developed method is investigated with high EV penetration in a typical distribution network. The simulation results demonstrates that HCA exploit EV flexibility to solve grid unbalancing and congestions with simultaneous maximization of economic benefits by ensuring EV participation to day-ahead, balancing, and regulation markets. For the given network configuration and pricing structure, HCA ensures the EV owners to get paid up to 5 times the cost they were paying without control.

24 POWER TRANSMISSION AND DISTRIBUTION↗
NASA NTRS1974

Turbulence flight director analysis and preliminary simulation

A control column and trottle flight director display system is synthesized for use during flight through severe turbulence. The column system is designed to minimize airspeed excursions without overdriving attitude. The throttle system is designed to augment the airspeed regulation and provide an indication of the trim thrust required for any desired flight path angle. Together they form an energy management system to provide harmonious display indications of current aircraft motions and required corrective action, minimize gust upset tendencies, minimize unsafe aircraft excursions, and maintain satisfactory ride qualities. A preliminary fixed-base piloted simulation verified the analysis and provided a shakedown for a more sophisticated moving-base simulation to be accomplished next. This preliminary simulation utilized a flight scenario concept combining piloting tasks, random turbulence, and discrete gusts to create a high but realistic pilot workload conducive to pilot error and potential upset. The turbulence director (energy management) system significantly reduced pilot workload and minimized unsafe aircraft excursions.

Johnson, D. E.↗
DOE OSTI2023

CoolPINNs: A physics-informed neural network modeling of active cooling in vascular systems

Emerging technologies like hypersonic aircraft, space exploration vehicles, and batteries avail fluid circulation in embedded microvasculatures for efficient thermal regulation. Modeling is vital during the design and operational phases of these engineered systems. However, many challenges exist in developing a modeling framework. What is lacking is an accurate framework that (i) captures sharp jumps in the thermal flux across complex vasculature layouts, (ii) deals with oblique derivatives (involving tangential and normal components), (iii) handles nonlinearity because of radiative heat transfer, (iv) provides a high-speed forecast for real-time monitoring, and (v) facilitates robust inverse modeling. Here, this paper addresses these challenges by availing the power of physics-informed neural networks (PINNs). We develop a fast, reliable, and accurate Scientific Machine Learning (SciML) framework for vascular-based thermal regulation—called CoolPINNs: a PINNs-based modeling framework for active cooling. The proposed mesh-less framework elegantly overcomes all the mentioned challenges. The significance of the reported research is multi-fold. First, the framework is valuable for real-time monitoring of thermal regulatory systems because of rapid forecasting. Second, researchers can address complex thermoregulation designs since the approach is meshless. Finally, the framework facilitates systematic parameter identification and inverse modeling studies, perhaps the most significant utility of the current framework.

97 MATHEMATICS AND COMPUTING↗