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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 163 records · Page 9

AmeriFlux FLUXNET-1F CA-SCC Scotty Creek Landscape

This is the AmeriFlux Management Project (AMP) created FLUXNET-1F version of the carbon flux data for the site CA-SCC Scotty Creek Landscape. This is the FLUXNET version of the carbon flux data for the site CA-SCC Scotty Creek Landscape produced by applying the standard ONEFlux (1F) software. Site Description - The Scotty Creek flux tower is located in an organic-rich boreal forest-wetland landscape about 50 km south of Fort Simpson in the Taiga Plains of the Mackenzie watershed. The tower was installed in 2013 and operates an open-path EC system year-round running on solar power only. Flux footprints contain about 50 % forested peat plateaus and 50 % wetlands (i.e., collapse-scar bogs). The forests are underlain by permafrost, while the treeless wetlands are permafrost-free. The tower itself is located on a forested peat plateau. Black spruce tree density on plateaus is sparse and the mean canopy height is ca. 5 m.

Sonnentag, Oliver↗

AmeriFlux US-UR3 Ft. Bridger - UCRB

This is the AmeriFlux version of the carbon flux data for the site US-UR3 Ft. Bridger - UCRB. Site Description - This site is located in Fort Bridger, Wyoming, within a flat grassland pasture. The region experiences cold winters with significant snow cover and mild summers. The land is primarily used for grazing, which influences both the vegetation and ecosystem.

Neale, C. U. [Daugherty Water for Food Institute/U↗

Production of Biocrude in an Advanced Photobioreactor-Based Biorefinery

Algenol Biotech, the National Renewable Energy Laboratory (NREL), Georgia Institute of Technology, Arizona State University, and Reliance Industries formed a team to advance the state of the art in algal biomass production and downstream processing technologies, with the end goal of a sustainable, economically viable biofuel intermediate (BFI, biocrude) product. The project included examination of high value co-product production as a market entry strategy and for enhancing the economics of a biorefinery for BFI production. The project targeted innovations in biology, operations, and engineering. The goals of the project were: BFI productivity greater than 4,000 gal-BFI/acre-yr on an annualized basis; energy efficient innovations in downstream operations resulting in an energy expenditure less than 10% of the BFI energy content and a carbon footprint reduction of more than 60% compared to fossil alternatives; and a comprehensive Techno-Economic Analysis (TEA) that identifies limiting factors for commercial viability of a photobioreactor (PBR)-based biofuel product. The project achieved the overall objectives. Strain development efforts led to the identification of a strain (Cyanobacterium sp. AB1166) that, relative to the previous best strain (Cyanobacterium sp. AB1), exhibited a ~10% increase in productivity under commercially-relevant cultivation conditions and also resulted in cultures with a >50% reduction in viscosity such that harvesting efficiency was improved; these results represent achievement of key project milestones. Progress was also made at NREL in altering the biochemical composition of algal biomass to improve the yield of BFI produced via HTL. These strain enhancements coupled with improved outdoor cultivation practices, including semi-continuous operation, increased areal biomass productivity by nearly 80% over the established baseline productivity. The annualized productivity achieved (26.8 g/m2-d), paired with HTL conversion yields realized at NREL and RIL (38% ± 2% BFI), translates to 4,100 gal-BFI/acre-yr, exceeding the FY20 BETO goal of 3,700 gal-BFI/acre-yr. Significant progress was also demonstrated in large scale PBR-based production system design, operability, and cost reduction. A 24,000-L production module comprised of 240 interlinked PBRs was constructed and successfully operated outdoors for over one year in Fort Myers, Florida. Aided by a state-of-the-art productivity model, the productivities achieved convincingly demonstrated scalability of laboratory results determined at the mL to L scale to large-scale outdoor operations exceeding 20,000 L. The system was used to cultivate Arthrospira platensis (Spirulina), an industrially-relevant cyanobacterium and source for phycocyanin, an approved blue food colorant that Algenol is developing as a risk reduction strategy for future biofuel projects and as a potential business opportunity. A key project milestone to develop phycocyanin extraction and purification technologies was achieved ahead of schedule, and product samples received positive feedback from potential customers. The production and downstream operations data generated in this project were used to conduct and refine Techno-Economic and Life Cycle Assessments to provide research guidance for reducing the costs and environmental footprint of algal biofuel and co-product manufacturing plants. Several CO 2 supply scenarios for an algal biorefinery were identified as being capable of providing a large (>60%) reduction in carbon footprint in comparison to gasoline. The TEA assessments incorporated detailed comparisons of PBR versus open pond production systems, yielding a 3-fold higher areal productivity for PBRs and suggesting overall production cost parity for the two systems. The progress in this ABY2 project addressed many of the the barriers identified for the Advanced Algal Systems R&D Program and are directly relevant to achieving the established BETO goals associated with large scale biofuel production and cost reduction.

09 BIOMASS FUELS↗

Collaboration with USACyS for Signals Manipulation

Savannah River National Laboratory has been investing into cybersecurity capabilities since 2019. Cybersecurity has been a rapidly growing area for the CSRA in general and has included the consolidation of Cyber and Electronic Warfare units at Fort Gordon. This consolidation has been driven by the convergence of cyberwarfare and electronic warfare as the technologies underpinning Army Cyber Command’s vision of Information Warfare. This convergence, investment by SRNL into cybersecurity for critical infrastructure, and the desire for collaboration between the Army and SRNL has resulted in an opportunity for SRNL to develop R&D capabilities in electronic warfare that will complement SRNL’s cybersecurity efforts. Discussions between SRNL and the U.S. Army Cyber School (USACyS) has identified a general gap in ICS training lab capability in which both entities could contribute to solve. It is proposed to design and architecture that meets this need.

97 MATHEMATICS AND COMPUTING↗

A Hierarchical Gibbs Sampler for Spatially Varying Multi-Regularization Image Reconstructions

This is a presentation for SIAM's (Society for Industrial and Applied Mathematics) conference on computational science and engineering. This presentation describes research on novel techniques to deblur images under a Bayesian framework. The title of the conference is SIAM Conference on Computational Science and Engineering (CSE21). This is a VIRTUAL conference; it was originally scheduled in Fort Worth, TX. The conference dates are March 1-5, 2021. The link to the conference's website is https://www.siam.org/conferences/cm/conference/cse21

97 MATHEMATICS AND COMPUTING↗

Transportation Hub Infrastructure Expansion: Decision Support Under Uncertainty

The Athena project (www.athena-mobility.org) has worked to investigate the relationship between the Dallas-Fort Worth Airport (DFW) and the greater Dallas area in order to better understand and therefore better inform future decision-making regarding the critical infrastructure that influence mobility between the airport and the city. Through this work, infrastructure related to curbside pickup and drop-off, parking, public transit, and the road network congestion were identified as critical to the operation of the DFW transportation hub. The infrastructure analysis and expansion aspect of the Athena project is focused on the restructuring of the CTA curb as a hierarchical curb and the building or repurposing of parking infrastructure as the interplay between these two areas. Many sources of uncertainty exist that may impact future airport and transportation hub operations, such as passenger volume growth, population demographic changes over time, electric vehicle (EV) adoption rates, and autonomous vehicle (AV) adoption rates. Due to these sources of uncertainty, we have selected for our research a modeling framework that can capture various types of uncertainty and hedge against those uncertainties in the optimization process. We analyze road network and curb congestion, the rise of transportation networking companies, trends in parking usage, existing policies around this infrastructure, airport revenue streams, and other contributing factors to enable infrastructure decision making with less uncertainty. To accomplish this wholistic analysis, we have developed a novel multi-stage, multi-period stochastic optimization model which considers the airport's decisions from 2025-2045 under different possible future macro trajectories and day-to-day variations in operational conditions captured as "annual representation of operations" scenarios with respective probabilities. This model has also been designed to leverage the outputs of various efforts under the Athena project to create a combined decision framework for infrastructure decisions. These various efforts include the route optimization model, the ASPIRES simulation, the mode choice model, and the SUMO traffic simulation. Our computational experiments of this system at scale have resulted in a working version of our infrastructure model which enables the explicit representation and consideration of various sources of uncertainty in the decision process to enable robust, flexible decision-making. This model has been effectively run on NREL's HPC system, Eagle, with large numbers of stochastic scenarios and shows promise as a scalable tool for robust consideration of uncertainties in airport planning. We have tested our model using 30,240 operational circumstances in total, resulting in a problem with more 200 million variables. This model was solved in several different configurations, and a workflow to simulate the performance of the infrastructure model results was developed and deployed. In general, our results indicate that a combination of remote parking, remote curb infrastructure, and dynamic pricing can generate revenue, reduce emissions, accommodate emerging technologies such as AVs and EVs, and manage airport passenger growth over time. We note the success of the proposed strategy depends on the data collection and forecasting abilities of DFW. We have also seen that the AV adoption by TNCs might necessitate larger amounts of remote curb. The results of this work inform strategies for airport infrastructure decision making, as well as demonstrate the value of an adaptable model, but also indicate that there are avenues remaining where further research would be of value.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

The Analysis and Support for LANL Technology Testbed: High Altitude Balloon Gondola and Orion Eagle Gamma Ray Detection Instrument

The Analysis and Support for LANL Technology Testbed: High Altitude Balloon Gondola and Orion Eagle Gamma-Ray Detection Instrument is a project where Los Alamos National Laboratory (LANL), in conjunction with the University of Michigan, are looking into gamma-ray detection in a space-like environment. The purpose of the detection is to work on instruments that can assist with planetary exploration and nuclear deterrents using a High-Altitude Balloon (HAB). For this paper, the main focus is on the mechanical aspects related to the structural analysis of the gondola. It is vital to understand the structural analysis because it helps determine if the gondola can survive the changes in the environment and the different forces or shocks that it will experience when the parachute is deployed and at landing. Additionally, NASA's Balloon Program Office (BPO) has specific requirements to meet to achieve flight certifications. Part of those certifications requires the gondola to simulate different scenarios at specific conditions with various forces applied and orientations. Therefore, it is necessary to adjust the calculations of each method and the force applied to get the right results. Once that is done, the information is inputted into the structural analysis modeling system. The system will aid the mechanical team in assessing the conditions of the gondola at each scenario and determine its margin of safety. After the gondola and instrument are certified, the payload will be able to fly. The HAB and payload are launched from NASA's Columbia Scientific Balloon Facility (CSBF) at Fort Sumner, NM. The official flight was on September 26th, 2021.

42 ENGINEERING↗

Initiating Event Rates at U.S. Nuclear Power Plants, 2021 Update

Analyzing initiating event rates is important because it indicates trends and patterns of plant performance and provides inputs to several U.S. Nuclear Regulatory Commission (NRC) risk-informed regulatory activities. This report presents an analysis of initiating event frequencies at U.S. commercial nuclear power plants from calendar year 1988 through 2021, as reported in licensee event reports. Engineers with nuclear power plant experience reviewed each event report since the last update to this report to categorize and characterize reactor trips. To be included in this study, an event had to meet all of the following criteria: (1) the event included an unplanned reactor trip (not a scheduled reactor trip on the daily operations schedule), (2) the sequence of events started when the reactor was critical and at or above the point of adding heat, (3) the event occurred at a U.S. commercial nuclear power plant (excluding Fort St. Vrain and LaCrosse), and (4) the event was reported by a licensee event report. Sixteen initiating event groupings are trended and displayed. For some of the categories, relevant events are plotted separately for boiling-water reactors (BWR) and pressurized-water reactors (PWR). P-values are given for the possible presence of a trend over the most recent 10 years. The following trends were identified for the most recent 10 years (2012–2021): • A highly statistically significant decreasing trend was identified for Loss of Offsite Power (p-value = 0.002) • A statistically significant decreasing trend was identified for BWR general transients (p-value = 0.025) • A statistically significant decreasing trend was identified for PWR general transients for the second year in a row (p-value = 0.038).

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

6 th International Conference on Plant Synthetic Biology, Bioengineering and Biotechnology (Workshop Report)

The objective of the project is to hold a Conference to bring together scientists and engineers from universities, industry and government working in all aspects of plant synthetic biology, plant bioengineering and plant biotechnology. To meet this objective, AIChE will host the 6th International Conference on Plant Synthetic Biology, Bioengineering and Biotechnology on December 9-11, 2022 in Fort Lauderdale, Florida. The conference will feature five technical sessions: (1) Genome and Epigenome Editing, (2) Specialized Metabolism, (3) Engineering Plant Resilience, (4) Engineering more efficient plants, and (5) New tools and Technologies. The conference will allow leading scientists and engineers from universities, industry and government to discuss new tools and technologies being developed as well as their applications, and gaps in the field. The conference will allow students to learn about these new technologies, engage in a discussion with professionals in their field of interest, and showcase their work. The scope, theme, and aims of the Conference on Plant Synthetic Biology, Bioengineering, and Biotechnology fall squarely within the mission of DOE which includes securing US leadership in energy technology and to maintaining a vibrant US effort in science and engineering as a cornerstone for our economic prosperity.

59 BASIC BIOLOGICAL SCIENCES↗

National User Resource for Biological Accelerator Mass Spectrometry Annual Report

The National User Resource for Biological Accelerator Mass Spectrometry (User Resource) will provide isotopic analysis (primarily radiocarbon or 14C) by accelerator mass spectrometry (AMS) for NIH- funded researchers across the United States and will be the only User Resource of its type in the United States. The User Resource will provide measurement capability and expertise to a research community that requires highly sensitive, quantitative isotope analyses. Since commissioning a new accelerator mass spectrometer in June 2014, we have measured over 4000 samples a year for collaborators and service users. The User Resource will enable us to continue to meet these research needs, as well as provide for new users whose research programs would benefit from AMS as a measurement tool. The User Resource’s forte will be ultra-high sensitivity quantitation of radiocarbon and selected other radioisotopes for research studies where isotopes are required. Radioisotope labeling studies have been and will continue to be an important tool for addressing many complex biomedical science problems. AMS is a specialized and unique type of mass spectrometry that provides absolute quantitation of radiocarbon and other relevant radioisotopes with extreme sensitivity, having limits of detection in real samples on the order of a few attomol/mg of sample at measurement precisions of ~3%. It is the only instrumental method capable of quantifying radioisotope-labeled agents routinely in real-world samples with such precision and sensitivity. The sensitivity of AMS allows for the quantification of radiolabeled metabolites in extremely complex matrices of cells and organisms at very low concentrations and in small samples. AMS allows studies to be conducted without perturbing metabolism leading to more relevant quantification of metabolic rates and pathways. In addition, it enables quantification of pharmacokinetic and metabolic properties of toxicants at environmentally relevant concentrations in model systems as well as the ability to quantify pharmacokinetics and other molecular endpoints directly in humans. Such quantitative assessments can 1) improve risk assessment for toxicants, 2) address safety and efficacy considerations for therapeutic entities, 3) deepen understanding of xenobiotic and intermediary metabolism, 4) help understand the interactions between critical molecular pathways, and 5) improve efforts to model and predict various metabolic and biological states. These capabilities have been applied in a number of areas including research in carcinogenesis, toxicology, nutrition, pharmacology/drug development and basic biological science.

59 BASIC BIOLOGICAL SCIENCES↗

2022 LaserNetUS Users' Meeting

Organized and funded in 2018 through the US Department of Energy, Office of Fusion Energy Sciences (FES), LaserNetUS was created to provide vastly improved access to unique lasers for researchers. LaserNetUS is a network of ten high-power laser facilities, both academic and national laboratories, across the United States and Canada. These labs operate many of the premier mid- to large-scale high-intensity laser facilities in the US and Canada that are designed to be used in pioneering experimental studies in high energy density plasma and high field optical science. The network’s principal goal is to provide access to these state-of-the-art laser facilities to a broad range of researchers in the US and abroad. In its over four years of operation, LaserNetUS has awarded beamtime for over 60 user experiments to researchers from 25 different institutions. Over 400 user scientists, many of whom are students and post-docs, have participated in experiments at LaserNetUS facilities so far. The network now has over 1250 members. The LaserNetUS institutions are Colorado State University, Lawrence Berkeley National Lab, Lawrence Livermore National Lab, SLAC National Lab, The Ohio State University, University of Michigan, University of Nebraska-Lincoln, Institut National de la Recherche Scientifique, University of Rochester, and University of Texas at Austin. LaserNetUS hosted its first in-person Annual Users’ Meeting at Colorado State University in Fort Collins, CO, Aug 16-18, 2022. The meeting had 158 attendees, including 39 sponsored students and post-docs whose attendance and travel to the meeting were covered by DOE funds. Attendees included the 2018 Nobel Laureate in Physics, Donna Strickland. The program consisted of 5 plenary talks and several invited and contributed talks, a user community forum, a poster session, and built-in time for networking. The event focused on students and early career professionals. The poster session was held in combination with a reception to facilitate discussions and maximize interactions between the participants. The 39 sponsored students each presented a poster at the poster session, giving them valuable practice in sharing their research with others in the field. Many students and postdocs also gave talks during the main programming. Lunch and coffee breaks were provided for attendees for the duration of the conference on CSU’s campus. This allowed for networking among all participants. The building used to host the conference also had plenty of seating outside the auditorium, which was conducive to smaller one-on-one meetings and discussions between participants. There was also a lab tour of CSU’s Advanced Beam Laboratory. The day before and after the conference also included satellite meetings for the lab PIs and the Scientific Advisory Board. DOE support was used for rental of the auditorium and supporting rooms, student participation, 50% of the food costs, and transportation to the Advanced Beam Lab.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Preparing Underrepresented Minorities for STEM Careers in Energy

The purpose of the grant was to increase the participation of underrepresented minorities and women in STEM disciplines that are critical for the energy industry. The grant was implemented by the Fort Valley State University’s (FVSU) Cooperative Developmental Energy Program (CDEP). FVSU-CDEP enrolled two cohorts of six academically talented freshmen students into its accelerated five-year 3+2 dual degree STEM program. In the 3+2 dual degree format, students enroll at FVSU for three years and earn bachelor’s degrees in biology, chemistry, or mathematics and transfer to a partnering university for two years to earn second bachelor’s degrees in engineering, geology/geophysics, or health physics. FVSU-CDEP partnering universities consist of Georgia Tech, Grand Valley State University, Penn State University, University of Alabama, University of Arkansas, University of Nevada-Las Vegas, and the University of Texas-Austin. Cohort I enrolled at FVSU fall semester of 2017 and cohort II enrolled fall semester of 2020. All six of the students in cohort I earned bachelor’s STEM degrees at FVSU and transferred to a partnering university. Five of the six who transferred to a partnering university earned the second bachelor’s degree. One student transferred from a partnering university to a non-partner university to continue pursuit of the second degree. All students in cohort I had internships, attended professional meetings, and made presentations. Cohort II enrolled the fall-semester of 2020 in the midst of COVID epidemic. Cohort II was only funded for one year, 2020/2021. The DOE Office of Economic Impact and Diversity informed the PI that there would not be any funding for the fifth and final year (2021/2022) of the project. All six of the students in cohort II earned bachelor’s STEM degrees from FVSU and transferred to one of CDEP’s partnering universities. One of the students in cohort II graduate with an MS degree spring of 2023. Currently, four are pursuing graduate degrees at partnering universities and one withdrew from a partnering school because health reasons. Students in cohort II opportunities to participate in internship were negatively impact by the COVID epidemic (2020-2022). Of the 12 scholarship participants, 8 were females. Fifty percent of the males pursued second degrees in Engineering while only twenty-five percent of the females chose Engineering as their second degree.

42 ENGINEERING↗

The Integration of Wi-Fi Location-Based Services to Optimize Energy Efficient Commercial Building Operations

This project investigated and demonstrated the use of Wi-Fi Location-Based Services (LBS) to perform occupancy sensing in commercial buildings. Wi-Fi LBS can be used to detect the presence of Wi-Fi enabled mobile devices and laptops that accompany occupants as they move through the building. These signals can be used to determine occupant presence, head count, and location. When integrated with the building automation system, this emerging technology approach can be used to manage other connected systems such as lighting and HVAC to reduce energy usage in the building and improve occupant comfort. An open source location detection algorithm was developed, which uses data collected from three or more Wi-Fi access points to determine the presence and estimate the location of mobile devices and laptops. Access points can detect Wi-Fi enabled devices even if they are not connected to the existing Wi-Fi network. Building occupancy is determined based on the presence, location, and movement of these devices through the space. From lab and small-scale in-situ testing, the Location Detection Algorithm (LDA) was found to be accurate to within 10 feet and could be further refined by tuning the algorithm for the specific space characteristics such as layout and obstructions (walls, furniture, etc.). An open source method to integrate the occupancy data with existing building automations systems was investigated. The Wi-Fi occupancy sensing approach was then demonstrated and validated at commercial buildings located in Saint Paul, MN; Madison, WI; New York City; and Fort Worth, TX.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Initiating Event Rates at U.S. Nuclear Power Plants: 2022 Update

Analyzing initiating event rates is important because it indicates trends and patterns of plant performance and provides inputs to several U.S. Nuclear Regulatory Commission (NRC) risk-informed regulatory activities. This report presents an analysis of initiating event frequencies at U.S. commercial nuclear power plants from calendar year 1988 through 2022, as reported in licensee event reports. Engineers with nuclear power plant experience reviewed each event report since the last update to this report to categorize and characterize reactor trips. To be included in this study, an event had to meet all of the following criteria: (1) the event included an unplanned reactor trip (not a scheduled reactor trip on the daily operations schedule), (2) the sequence of events started when the reactor was critical and at or above the point of adding heat, (3) the event occurred at a U.S. commercial nuclear power plant (excluding Fort St. Vrain and LaCrosse), and (4) the event was reported by a licensee event report. Sixteen initiating event groupings are trended and displayed. For some of the categories, relevant events are plotted separately for boiling-water reactors (BWR) and pressurized-water reactors (PWR). P-values are given for the possible presence of a trend over the most recent 10 years.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Equipment Qualification Report Environmental Qualification of GNB Absolyte Valve Regulated Lead Acid (VRLA) 1600 Ah100G33 Battery Rack Assembly (24590-QL-POA-EDB0-00001-11-00002_00A)

Greenberry Environmental Qualification Report 550001.001-35.0.5 provides basis for assignment of qualified life for: GNB Absolyte Valve Regulated Lead Acid (VRLA) 1600 Ah 100G33 Battery Rack Assembly in accordance with the requirements specified 24590-WTP-3PS-G000-T0015 (Rev 2) and Environmental Qualification Plan 550001.001-35.0.1 (Rev. 3). The equipment qualification basis represents the most conservative capability of the equipment. The analysis performed for the qualification is not less conservative than the bounding environmental conditions detailed in contract documents issued to Greenberry in contract 24509-QL-POA-EDB0-00001 Rev.0. The qualified life of 10 years has been established based upon an end-condition objective of the equipment condition indicators that correlate to the ability of equipment to perform its safety function. The VRLA Battery Cell Assembly was aged by 10 years (minimum) in accordance with conditions specified by Bechtel Equipment Qualification Datasheet 24590-LAW-EUQ-UPE 00003 Rev. 3 and the process conditions specified by the Instrument Data Sheet 24590-LAW EUD-UPE-00009 Rev. 2. Greenberry Industrial has contracted with GNB Industrial Battery Co located at 4115 S Zero St, Fort Smith, AR 72908 to perform age conditioning, monitoring, and capacity testing in accordance with Environmental Qualification Plan 550001.001-35.0.1 Rev. 1. The required process at the stated conditions set by the parameters established by the plan were completed satisfactorily. The details of the of the test process observed by Greenberry is detailed in the attached Seismic Test Log 550001.001-7.0.3, including examples of the objective evidence collected during the qualification process.

54 ENVIRONMENTAL SCIENCES↗

National User Resource for Biological Accelerator Mass Spectrometry

The National User Resource for Biological Accelerator Mass Spectrometry (User Resource) will provide isotopic analysis (primarily radiocarbon or 14C) by accelerator mass spectrometry (AMS) for NIH- funded researchers across the United States and will be the only User Resource of its type in the United States. The User Resource will provide measurement capability and expertise to a research community that requires highly sensitive, quantitative isotope analyses. Since commissioning a new accelerator mass spectrometer in June 2014, we have measured over 4000 samples a year for collaborators and service users. The User Resource will enable us to continue to meet these research needs, as well as provide for new users whose research programs would benefit from AMS as a measurement tool. The User Resource’s forte will be ultra-high sensitivity quantitation of radiocarbon and selected other radioisotopes for research studies where isotopes are required. Radioisotope labeling studies have been and will continue to be an important tool for addressing many complex biomedical science problems. AMS is a specialized and unique type of mass spectrometry that provides absolute quantitation of radiocarbon and other relevant radioisotopes with extreme sensitivity, having limits of detection in real samples on the order of a few attomol/mg of sample at measurement precisions of ~3%. It is the only instrumental method capable of quantifying radioisotope-labeled agents routinely in real-world samples with such precision and sensitivity. The sensitivity of AMS allows for the quantification of radiolabeled metabolites in extremely complex matrices of cells and organisms at very low concentrations and in small samples. AMS allows studies to be conducted without perturbing metabolism leading to more relevant quantification of metabolic rates and pathways. In addition, it enables quantification of pharmacokinetic and metabolic properties of toxicants at environmentally relevant concentrations in model systems as well as the ability to quantify pharmacokinetics and other molecular endpoints directly in humans. Such quantitative assessments can 1) improve risk assessment for toxicants, 2) address safety and efficacy considerations for therapeutic entities, 3) deepen understanding of xenobiotic and intermediary metabolism, 4) help understand the interactions between critical molecular pathways, and 5) improve efforts to model and predict various metabolic and biological states. These capabilities have been applied in a number of areas including research in carcinogenesis, toxicology, nutrition, pharmacology/drug development and basic biological science. As a NIGMS National Resource the National User Resource for Biological Accelerator Mass Spectrometry will help NIH funded scientists achieve a deeper understanding of the etiology of human health concerns by (1) enabling the quantification of pharmacokinetics and other molecular endpoints directly in humans; (2) offering the ability to conduct quantitative studies using biologics such as proteins or lipids, and thereby reducing the amount of radioisotope usage in biomedical labs; and (3) enabling more relevant studies of metabolic pathways in health and disease through the use of much lower, more biologically-relevant, concentrations of metabolic substrates in cells and intact organisms. Such studies support NIGMS’s basic biomedical research areas that contribute to the understanding of fundamental cellular and physiological principles and enable research supported by the Biophysics, Biomedical Technology, and Computational Biosciences (BBCB); Genetics and Molecular, Cellular, and Developmental Biology (GMCDB); Pharmacology, Physiology, Biological Chemistry (PPBC) and Training, Workforce Development, and Diversity (TWD) Divisions.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

A Framework for Identifying Building Energy Models of Localized Utility Service Areas Using Smart Meter Data

Bottom-up load modeling of buildings offers a versatile approach to simulating baseline demand and scenarios of future technology evolution and adoption at the individual building level. This capability is essential to understanding how future load shapes may change with the adoption of electric equipment and vehicles, particularly as it relates to grid planning and infrastructure investments. Traditionally, grid planning techniques have used historical load data to predict future load and infrastructure needs. However, with the anticipated rise in adoption of electrification technologies such as heat pumps and electric vehicles, historical data become less reliable predictors of the future. By employing ResStock, a high-fidelity building stock modeling tool, we can fine-tune electrification scenarios and aggregate models to represent varying geographic resolutions of the grid system, while considering the underlying features of homes. This may enable a more accurate and responsive approach to anticipate and plan for the evolving landscape of energy demands. We present a new framework that leverages building stock energy modeling to identify building models that align with the load shapes and housing attributes of buildings with AMI data. This approach applies two model layers: (1) a classification step that identifies the presence of air conditioning, electric heating, and electric water heating, and (2) an optimization routine that identifies building energy models aligning with load profile data from advanced metering infrastructure meters. This report demonstrates one approach to deploying this framework, and presents results for three test cases that use both modeled and AMI data to assess performance. For a test case using AMI data in Fort Collins, Colorado, we observed a median monthly electricity load CV-RMSE of 16.6%, and a top ten daily heating and cooling median absolute percent error of 7.7% and 8.3%, respectively. For each AMI meter, we identify a set of potential energy models so that downstream use-cases can account for uncertainty driven by variability of baseline technologies and occupant behavior, which impact the response to electrification and energy efficiency scenarios. Our results indicate that ResStock has potential as a scalable solution for modeling residential energy demand at local grid resolutions. Its performance depends on location-specific factors, underlying building characteristics, and the level of aggregation, offering a path towards more precise and adaptive distribution grid planning for the evolving energy landscape.

24 POWER TRANSMISSION AND DISTRIBUTION↗

I-80 Mid-America Clean Fuels Corridor: Deployment Plan Report

The I-80 Mid-America Clean Fuels Corridor, which spans I-80 from Fort Lee, New Jersey, to Council Bluffs, Iowa, was designated an Alternative Fuels Corridor (AFC) in Round 1 of the Alternative Fuels Corridor program administered by the U.S. Department of Transportation’s (DOT’s) Federal Highway Administration (FHWA). Originally called the “I-80 Mid-America Alternative Fuels Corridor,” it is now named the “I-80 Mid-America Clean Fuels Corridor.” As of Round 6 AFC designation, parts of the corridor have sufficient direct current fast charging (DCFC) stations to be designated Electric Vehicle (EV)-Ready and sufficient compressed natural gas (CNG) fueling stations to be designated CNG-Ready. However, much of the corridor’s approximately 1,240 miles (mi) are not yet EV- or CNG-Ready. This includes about 1,130 mi that are designated EV-Pending and 700 mi that are designated CNG-Pending. This report presents a plan to develop EV charging and CNG fueling infrastructure sufficient to convert the entire length of the corridor to EV-Ready and CNG-Ready. Specific sites are not identified for future infrastructure. Rather, priority exits are identified, and information, analysis, and additional steps are recommended to support further refinement of these locations, as well as additional outreach and deployment efforts.

24 POWER TRANSMISSION AND DISTRIBUTION↗