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St. Jude Medical's (formerly known as Pacesetter Systems, Inc.) Programmable Rechargeable Neuropacemaker (PRN) is an implantable human tissue stimulator designed to provide relief to patients with disorders treatable by electrical stimulation. Examples are back, leg, and arm pain, cancer pain and multiple sclerosis.
Bit error rate is measured by sending a pseudo-random noise (PRN) code test signal simulating digital data through digital equipment to be tested. An incoming signal representing the response of the equipment being tested, together with any added noise, is received and tracked by being compared with a locally generated PRN code. Once the locally generated PRN code matches the incoming signal a tracking lock is obtained. The incoming signal is then integrated and compared bit-by-bit against the locally generated PRN code and differences between bits being compared are counted as bit errors.
Spurious interference limits the performance of many interferometric measurements. Digitally enhanced interferometry (DEI) improves measurement sensitivity by augmenting conventional heterodyne interferometry with pseudo-random noise (PRN) code phase modulation. DEI effectively changes the measurement problem from one of hardware (optics, electronics), which may deteriorate over time, to one of software (modulation, digital signal processing), which does not. DEI isolates interferometric signals based on their delay. Interferometric signals are effectively time-tagged by phase-modulating the laser source with a PRN code. DEI improves measurement sensitivity by exploiting the autocorrelation properties of the PRN to isolate only the signal of interest and reject spurious interference. The properties of the PRN code determine the degree of isolation.
Digitally enhanced heterodyne interferometry (DI) is a laser metrology technique employing pseudo-random noise (PRN) codes phase-modulated onto an optical carrier. Combined with heterodyne interferometry, the PRN code is used to select individual signals, returning the inherent interferometric sensitivity determined by the optical wavelength. The signal isolation arises from the autocorrelation properties of the PRN code, enabling both rejection of spurious signals (e.g., from scattered light) and multiplexing capability using a single metrology system. The minimum separation of optical components is determined by the wavelength of the PRN code.
The organic compounds of carbonaceous chondrites are structurally diverse products of the prolonged abiotic chemistry that occurred before and during the early stages of the solar system. They also represent the types of prebiotic compounds that may have participated in chemical evolutionary processes that gave rise to life. Pyruvic acid is a key component of primary metabolism that has recently been found in carbonaceous chondrites. Its prominence in biology has inspired us to explore its chemistry and possible role in the origin of metabolism. Our laboratory investigations have found that pyruvate (the ionized form of pyruvic acid) can serve as a single-source reactant to generate what we term a pyruvate reaction network (PRN). The core of the PRN is driven by pyruvate aldol polymerization and decay reactions. These decay reactions lead to the production of stable and unstable compounds which include mono, di, and tricarboxylic acids and a variety of keto acids. Importantly, many of these reactions apparently lead back to pyruvate, establishing a feedback process. Finding evidence of this reaction network in meteorites would establish that the chemistry of pyruvate did occur in a prebiotic environment and indeed many of the known compounds found in pyruvate reaction mixtures were detected in the Murchison and Murray meteorites. However, multiple synthetic origins, not tied to pyruvate chemistry, might also explain their meteoritic presence. Thus finding compounds unique to the PRN, such as reaction intermediates, would provide stronger evidence in support of its prebiotic relevance. The identity of these intermediates can only be con-firmed by acquiring chemical standards, however, as most are not available commercially, we engaged in extensive chemical synthesis. Obtaining these standards also provides the opportunity to study their subsequent chemistry and roles in the PRN.
The organic compounds of carbonaceous chondrites are structurally diverse products of the prolonged abiotic chemistry that occurred before and during the early stages of the solar system. They also represent the types of prebiotic compounds that may have participated in chemical evolutionary processes that gave rise to life. Pyruvic acid is a key component of primary metabolism that has recently been found in carbonaceous chondrites. Its prominence in biology has inspired us to explore its chemistry and possible role in the origin of metabolism. Our laboratory investigations have found that pyruvate (the ionized form of pyruvic acid) can serve as a single-source reactant to generate what we term a pyruvate reaction network (PRN). The core of the PRN is driven by pyruvate aldol polymerization and decay reactions. These decay reactions lead to the production of stable and unstable compounds which include mono, di, and tricarboxylic acids and a variety of keto acids. Importantly, many of these reactions apparently lead back to pyruvate, establishing a feedback process. Finding evidence of this reaction network in meteorites would establish that the chemistry of pyruvate did occur in a prebiotic environment and indeed many of the known compounds found in pyruvate reaction mixtures were detected in the Murchison and Murray meteorites. However, multiple synthetic origins, not tied to pyruvate chemistry, might also explain their meteoritic presence. Thus finding compounds unique to the PRN, such as reaction intermediates, would provide stronger evidence in support of its prebiotic relevance. The identity of these intermediates can only be confirmed by acquiring chemical standards, however, as most are not available commercially, we engaged in extensive chemical synthesis. Obtaining these standards also provides the opportunity to study their subsequent chemistry and roles in the PRN.
A pseudorandom noise (PRN) generator functional design has been developed which is superior to the commercially available instrument in usable bandwidth and in the closeness of fit to the gaussian probability distribution in the 'tails' of the curve. The principal disadvantage of PRN sources for bit error rate (BER) measurements is that the probability distribution is truncated in the tails. This truncation of the probability distribution results in a similar truncation of the BER curve - i.e., there is a minimum BER which can be measured, below which the only possible result is zero. The minimum nonzero BER actually computed with the PRN source developed was 0.00001 with a pseudorandom sequence of 131,071 bits. It is theoretically possible, with a longer sequence, to achieve a minimum BER of 0.000001 with the same design.
The Satellite Time and Frequency Transfer System is intended to provide, simultaneously, global time comparisons at the subnanosecond level and frequency comparisons to better than 1 part in 10 to the 14th power. It utilizes an orbiting hydrogen maser clock and frequency standard that communicates, via microwave links, time and frequency information to Earth terminals operated by hydrogen masers controlling local clocks. A two-way microwave link, to and from the space vehicle provides Doppler information used to cancel the Doppler shifts in a one-way link from the spaceborne oscillator. Pseudo-random noise (PRN) modulation in the two-way link also provides range information to cancel the range delay in the PRN time transfer between space and Earth. The pseudo-random noise modulation system for time difference measurement and its incorporation in the Doppler cancellation system for frequency comparison is explained. The particular PRN code sequence selected and an analysis of the system is discussed.
The organic compounds of carbo- naceous chondrites are structurally diverse products of the prolonged abiotic chemistry that occurred before and during the early stages of the solar system [1]. They also represent the types of prebiotic compounds that may have participated in chemical evolutionary processes that gave rise to life [2]. Pyruvic acid is a key component of primary metabolism that has recently been found in carbonaceous chondrites [3]. Its prominence in biology has inspired us to explore its chemistry and possible role in the origin of metabolism. Our laboratory investigations have found that pyruvate (the ionized form of pyruvic acid) can serve as a single-source reactant to generate what we term a pyruvate reaction network (PRN). The core of the PRN is driven by pyruvate aldol polymerization and decay reactions. These decay reactions lead to the production of stable and unstable compounds which include mono, di, and tricarboxylic acids and a variety of keto acids. Finding evidence of this reaction network in meteorites would establish that the chemistry of pyruvate did occur in a prebiotic environment. Many of the known compounds found in pyruvate reaction mixtures were originally detected in meteorite samples by Cooper et al in 2011. However, multiple synthetic origins not tied to pyruvate chemistry might also explain their meteoritic presence. Thus, a search to find compounds unique to the PRN, such as reaction intermediates, would provide stronger evidence to demonstrate its prebiotic relevance. The identity of these intermediates can only be confirmed by acquiring chemical standards, however, as most are not available commercially, they need to be accessed through chemical synthesis.
INTRODUCTION The Human Systems Risk Board (HSRB) is responsible for understanding, managing, and mitigating the risks associated with spaceflight. For a particular mission, the HSRB assigns each human system risk a rating on a 5x5 grid assessing its likelihood and consequence, which is ultimately used to compare and rank the risks. The HSRB approaches risk management by primarily establishing the context of each human system risk individually with the understanding that mitigating one risk might affect the likelihood, consequence, and mitigation approaches of another. To support this effort the HSRB, subject matter experts, and risk custodian teams created directed acyclic graphs (DAG), often called a causal graph, for the twenty-nine risks. In this presentation, we propose a new ranking algorithm for the risks which includes the downstream influence of each risk according to the information in the DAGs and provide an application of graph theoretic tools. METHODS In 2014, Mindock and Klaus proposed a taxonomy for human system risk influences which we have adopted to categorize the nodes in each DAG. Analyzing the nodes that correspond to the risks in this taxonomy allows us to analyze and understand how each risk influences the others. We construct an auxiliary network, which we call the Primary Risk Network (PRN), where the nodes are the twenty-nine space flight risks and, a directed edge connects Risk A to Risk B if Risk A has some influence on the likelihood or consequence of Risk B as described in the DAGS. We perform a variety of graph theoretic ranking methods on the nodes (or risks) in the PRN, including Katz centrality. RESULTS We rank the nodes in the PRN using the Katz centrality score. The ten risks with the highest score are pictured in Figure 1, colored (light to dark) according to their score. We analyze other centrality measures like betweenness centrality, eigenvector centrality, and the Estrada index, and provide the meaning of the corresponding rankings in terms of the risks. Future work includes analyzing the other categories in the taxonomy defined by Mindock and Klaus [1]. For example, we are interested in analyzing the nodes that are labeled as countermeasures or capabilities and perform similar analysis to measure their effect on certain medical conditions.
The Naval Research Laboratory (NRL) has developed a two way time transfer modem system for the United States Naval Observatory (USNO). Two modems in conjunction with a pair of Very Small Aperture Terminal (VSAT) and a communication satellite can achieve sub nanosecond time transfer. This performance is demonstrated by the results of testing at and between NRL and USNO. The modems use Code Division Multiple Access (CDMA) methods to separate their signals through a single path in the satellite. Each modem transmitted a different Pseudo Random Noise (PRN) code and received the others PRN code. High precision time transfer is possible with two way methods because of reciprocity of many of the terms of the path and hardware delay between the two modems. The hardware description was given in a previous paper.
A submicrosecond time dissemination system was developed. The system is composed of an experimental transit improvement satellite (TRIAD), TRANET Satellite Tracking System, and special satellite signal receivers each tied to separate cesium clocks. The 400 MHz signal from the satellite is phase modulated plus or minus 45 deg by a pseudo-random noise (PRN) digital code with a bit rate of 5/3 MHz. Evaluation of this system has shown that satellite oscillator frequency instabilities are the major source of error. Experiments indicate that Global time transfers can be made with errors less than 100 nanoseconds.
An experiment was designed to launch a corner cube retroreflector array on one of the Global Positioning Satellites (GPS). The launch on Aug. 31, 1993 ushered in the era of SLR tracking of GPS spacecraft. Once the space operations group finished the check-out procedures for the new satellite, the agreed upon SLR sites were allowed to track it. The first site to acquire GPS-35 was the Russian system at Maidanak and closely after the MLRS system at McDonald Observatory, Texas. The laser tracking network is currently tracking the GPS spacecraft known as GPS-35 or PRN 5 with great success. From the NASA side there are five stations that contribute data regularly and nearly as many from the international partners. Upcoming modifications to the ground receivers will allow for a further increase in the tracking capabilities of several additional sites and add some desperately needed southern hemisphere tracking. We are analyzing the data and are comparing SLR-derived orbits to those determined on the basis of GPS radiometric data.
The Mars Organic Detector (MOD) is designed to assess whether organic compounds, possibly associated with life, are present in Martian rock and soil samples. MOD has a detection limit that is at least two orders of magnitude more sensitive than the Viking GCMS. MOD is focused on detecting amino acids, amines and PAH (polycyclic aromatic hydrocarbons). Amino acids play an essential role in biochemistry on Earth and PAH are widespread throughout the universe and can provide an indication of the delivery of meteoritic organic material to Mars. The advantage of MOD is the absence of wet chemistry and its simple and robust design. The sample will be extracted from the mineral matrix (0.1 - 1 g of rock-powder) using sublimation and analyzed with a fluorescence detector. The isolation method is based on the fact that amino acids and PAH are volatile at temperatures greater than 150C. The fluorescence detection scheme is based on UV excitation with LED's, optical filters, PrN diode photon detector and a sample calibration reservoir. Fluorescamine is used as a fluorescing reagent for amino acids and amines, while PAH are naturally fluorescent. There is no sample preparation required and the turnaround time for a single analysis is on the order of minutes.
The ionospheric-free (Lc) phase center of the GPS transmit antenna is modeled as a fixed constant in most geodetic software packages. We estimated a phase center offset for all GPS satellites and found large deviations from the nominal values. In particular, meter level deviation was observed for PRN 13 and somewhat smaller anomalies were observed for PRNs 6, 15, 19 and 31. We will present the estimation results for all GPS satellites and describe the estimation process as well as an error budget. We will present evidence that estimating the phase center offset improves the GPS orbits and discuss the impact of phase center mismodeling on various high-precision applications.
A real-time software receiver that executes on a general purpose processor. The software receiver includes data acquisition and correlator modules that perform, in place of hardware correlation, baseband mixing and PRN code correlation using bit-wise parallelism.
A real-time software receiver that executes on a general purpose processor. The software receiver includes data acquisition and correlator modules that perform, in place of hardware correlation, baseband mixing and PRN code correlation using bit-wise parallelism.
NASA's twin GRAIL [1] spacecraft (Ebb and Flow) arrived at Earth's Moon on New Year's Day, 2012. GRAIL's primary mission is to create a high-resolution map of the Moon's gravitational field by measuring very precisely the change in distance between the two spacecraft [2]. Each spacecraft transmits two signals to the other spacecraft, a PRN code modulated on a 2 GHz carrier (S-band), as well as an unmodulated carrier at roughly 33 GHz (Ka-band). Since it's not feasible to synchronize the two GRAIL spacecraft's clocks via GPS (as was done with GRACE), the S-band signals are used as a time-transfer link to synchronize either Ebb's clock to Flow or vice versa. As an independent measure to determine the clock offset of the GRAIL ultra-stable oscillators to UTC(NIST), an experiment was conducted where our JPL team used a large antenna on Earth to eavesdrop on the inter-spacecraft time-transfer link.