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At least 19 records

The dynamics of fibril magnetic fields. III - Fibril configurations in steady flows. IV - Trapping in closed convective rolls

The present investigation has the objective to provide an illustration of the equilibrium form of a hypothetical fibril field beneath the surface of the sun. Equilibrium fibril paths in static and moving atmospheres are considered. The provided examples are related to horizontal flows in an atmosphere in which the two anchor points of the arched fibril lie along the flow direction relative to each other. A brief introduction to the subject of the motion of horizontal fibrils in convective rolls is also presented, taking into account some implications for the sun. The equations of motion for a slender, buoyant flux tube extending horizontally along a closed convective roll are solved to illustrate the motion of the flux tube relative to the fluid, and attention is given to theoretical possibilities for the escape of flux tubes from a large horizontal convective roll in the sun.

Parker, E. N.↗

Stellar fibril magnetic systems. I - Reduced energy state

The remarkable fibril structure of the magnetic fields at the surface of the sun (with fibrils compressed to 1,000-2,000 gauss) lies outside existing statistical theories of magnetohydrodynamic turbulence. The total energy of the fibril field is enhanced by a factor of more than 100 above the energy for the mean field in a continuum state. The magnetic energy density within a fibril is of the order of 100 times the local kinetic energy density, so that no simple application of equipartition principles is possible. It is pointed out that the total energy of the atmosphere (thermal + gravitational + magnetic) is reduced by the fibril state of the field by avoiding the magnetic inhibition of the convective overturning, suggesting that the formation of the observed intense fibril state may be in response to the associated energy reduction. Calculation of the minimum total energy of a polytropic atmosphere permeated by magnetic fibrils yields theoretical fibril fields of the order of 1-5 kilogauss when characteristics appropriate to the solar convective zone are introduced, in rough agreement with the actual fields of 1-2 kilogauss. The polytrope model, although crude, establishes that a large reduction in total energy is made possible by the fibril state.

Parker, E. N.↗

The lifetime and evolution of fibrils

A detailed study was made of the lifetimes and evolution of fibrils in McMath 12417, using high resolution filtergrams in H alpha and CaII K made at Big Bear Solar Observatory. It was found that the lifetime of a fibril increases monotonically with its length. This relationship, together with the form of the variation of fibril lengths as a function of time, suggests that fibrils result from material being impulsively injected into magnetic field lines at approximately 30 km/sec, and returning under gravity. The lifetimes and apparent lengths of fibrils are then a function of the inclination of the field lines only. A study of wavelength scans through the H alpha line confirms that the apparent expansion and contraction of fibrils represents true mass motion.

Marsh, K. A.↗

The lifetime and evolution of fibrils

A detailed study has been made of the lifetimes and evolution of fibrils in McMath 12417, using high resolution filtergrams in H-alpha and Ca II K. It was found that when viewed near disk center, the lifetime of a fibril is a monotonically increasing function of its maximum apparent length. This relationship, together with the form of the variation of fibril lengths as a function of time, suggests that fibrils result from material being impulsively injected into magnetic field lines at approximately 30 km/sec, and returning under gravity. The lifetimes and apparent lengths of fibrils are then a function of the inclination of the field lines only. A study of wavelength scans through the H-alpha line confirms that the apparent extension and retraction of fibrils represents true mass motion.

Marsh, K. A.↗

Conventional heart rate variability analysis of ambulatory electrocardiographic recordings fails to predict imminent ventricular fibrillation

OBJECTIVES. The purpose of this report was to study heart rate variability in Holter recordings of patients who experienced ventricular fibrillation during the recording. BACKGROUND. Decreased heart rate variability is recognized as a long-term predictor of overall and arrhythmic death after myocardial infarction. It was therefore postulated that heart rate variability would be lowest when measured immediately before ventricular fibrillation. METHODS. Conventional indexes of heart rate variability were calculated from Holter recordings of 24 patients with structural heart disease who had ventricular fibrillation during monitoring. The control group consisted of 19 patients with coronary artery disease, of comparable age and left ventricular ejection fraction, who had nonsustained ventricular tachycardia but no ventricular fibrillation. RESULTS. Heart rate variability did not differ between the two groups, and no consistent trends in heart rate variability were observed before ventricular fibrillation occurred. CONCLUSIONS. Although conventional heart rate variability is an independent long-term predictor of adverse outcome after myocardial infarction, its clinical utility as a short-term predictor of life-threatening arrhythmias remains to be elucidated.

Non-NASA Center↗

Atrial Fibrillation During an Exploration Class Mission

Background: A long-duration exploration class mission is fraught with numerous medical contingency plans. Herein, we explore the challenges of symptomatic atrial fibrillation (AF) occurring during an exploration class mission. The actions and resources required to ameliorate the situation, including the availability of appropriate pharmaceuticals, monitoring devices, treatment modalities, and communication protocols will be investigated. Challenges of Atrial Fibrillation during an Exploration Mission: Numerous etiologies are responsible for the initiation of AF. On Earth, we have the time and medical resources to evaluate and determine the causative situation for most cases of AF and initiate therapy accordingly. During a long-duration exploration class mission resources will be severely restricted. How is one to determine if new onset AF is due to recent myocardial infarction, pulmonary embolism, fluid overload, thyrotoxicosis, cardiac structural abnormalities, or CO poisoning? Which pharmaceutical therapy should be initiated and what potential side effects can be expected? Should anti-coagulation therapy be initiated? How would one monitor the therapeutic treatment of AF in microgravity? What training would medical officers require, and which communication strategies should be developed to enable the best, safest therapeutic options for treatment of AF during a long-duration exploration class mission? Summary: These questions will be investigated with expert opinion on disease elucidation, efficient pharmacology, therapeutic monitoring, telecommunication strategies, and mission cost parameters with emphasis on atrial fibrillation being just one illustration of the tremendous challenges that face a long-duration exploration mission. The limited crew training time, medical hardware, and drugs manifested to deal with such an event predicate that aggressive primary and secondary prevention strategies be developed to protect a multibillion-dollar asset like the International Space Station or a mission to the Moon or Mars. Learning Objectives: The audience will become familiar with the risks and challenges inherent to developing a therapeutic strategy for the treatment of atrial fibrillation during a long-term exploration class mission.

Lipset, Mark A.↗

Reinforcement of polymeric structures with asbestos fibrils

Investigation determines structural potential of asbestos fibrils. Methods are developed for dispersing macrofibers of the asbestos into colloidal-sized ultimate fibrils and incorporating these fibrils in matrices without causing reagglomeration.

Rader, C. A.↗

A rebound shock mechanism for solar fibrils

Flows along a rigid solar magnetic flux tube which is horizontal over a substantial portion of its length are numerically investigated. A single, quasi-impulsive force near the base of the first vertical segment drives a series of upward propagating rebound shocks on the flux tube. When the horizontal segment is in the corona, the shocks raise the transition region onto the horizontal segment and eventually onto the coronal vertical segment. The material behind the displaced transition region resembles a fibril on the horizontal segment, and a short spicule on the second vertical segment. A full-sized spicule does not develop. The resulting density of the material on the horizontal segment is 10 to the -14th g/cu cm, which is consistent with the observed densities in fibrils. When the horizontal segment is in the chromosphere, the motions and densities induced on the horizontal segment do not resemble those of observed fibrils, and a full-sized spicule again does not develop.

Sterling, Alphonse C.↗

Cross-linking connectivity in bone collagen fibrils: the COOH-terminal locus of free aldehyde

Quantitative analyses of the chemical state of the 16c residue of the alpha 1 chain of bone collagen were performed on samples from fetal (4-6-month embryo) and mature (2-3 year old) bovine animals. All of this residue could be accounted for in terms of three chemical states, in relative amounts which depended upon the age of the animal. Most of the residue was incorporated into either bifunctional or trifunctional cross-links. Some of it, however, was present as free aldehyde, and the content increased with maturation. This was established by isolating and characterizing the aldehyde-containing peptides generated by tryptic digestion of NaB3H4-reduced mature bone collagen. We have concluded that the connectivity of COOH-terminal cross-linking in bone collagen fibrils changes with maturation in the following way: at first, each 16c residue in each of the two alpha 1 chains of the collagen molecule is incorporated into a sheet-like pattern of intermolecular iminium cross-links, which stabilizes the young, nonmineralized fibril as a whole. In time, some of these labile cross-links maturate into pyridinoline while others dissociate back to their precursor form. The latter is likely due to changes in the molecular packing brought about by the mineralization of the collagen fibrils. The resultant reduction in cross-linking connectivity may provide a mechanism for enhancing certain mechanical characteristics of the skeleton of a mature animal.

NASA Discipline Musculoskeletal↗

Computer simulation of fibrillation threshold measurements and electrophysiologic testing procedures

A finite element model of cardiac conduction was used to simulate two experimental protocols: 1) fibrillation threshold measurements and 2) clinical electrophysiologic (EP) testing procedures. The model consisted of a cylindrical lattice whose properties were determined by four parameters: element length, conduction velocity, mean refractory period, and standard deviation of refractory periods. Different stimulation patterns were applied to the lattice under a given set of lattice parameter values and the response of the model was observed through a simulated electrocardiogram. The studies confirm that the model can account for observations made in experimental fibrillation threshold measurements and in clinical EP testing protocols.

NASA Discipline Cardiopulmonary↗

Effect of a fibril magnetic field on solar p-modes

The dispersion relation is obtained for acoustic plane waves that scatter coherently from an ensemble of parallel magnetic flux tubes when the wave vector is perpendicular to the flux-tube axis. When the magnetic flux tubes are distributed uniformly and possess radii that are small compared with the wavelength, the frequency can be calculated exactly. The waves are damped slightly due to a loss of coherence and are shifted downward or upward in frequency relative to a medium devoid of magnetic fibrils, depending primarily on whether the flux tubes are more or less dense than their surroundings. It is suggested that the influence of the fibril magnetic fields observed at the solar surface cannot be ignored in the interpretation of high-1 surface p-mode data.

Bogdan, T. J.↗

The fibril structure of prominences

It is suggested that the fibril structure of prominences may be caused by filamentation during its formation by radiative instability. Also discussed are the effects of other types of instability and a mechanism for the formation of vertical threads is given. The models indicate that highly inhomogeneous density structures can exist in the presence of smooth profiles for the plasma pressure and magnetic field. In the particular models the plasma pressure of a fibril prominence is higher and the vertical magnetical field is weaker than in a uniform prominence model, while the mass is substantially smaller.

Priest, E. R.↗

Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat

The effect of administering the serotonin precursor 5-l-hydroxytryptophan, in conjunction with a monamine oxidase inhibitor phenelzine and a l-amino acid decarboxylase inhibitor carbidopa, on neurochemical changes in the concentrations of serotonin and 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid of the cat were investigated. Results showed that this drug regimen led to increases of serotonin and 5-hydroxyindoleacetic acid (5-HIAA) concentrations in the cerebrospinal fluid by 330 and 830 percent, respectively. Concomitantly, the threshold of ventricular fibrillation was found to be elevated by 42 percent and the effective refractory period was prolonged by 7 percent; the efferent sympathetic neural activity was suppressed in the normal heart. The results indicate that the enhancement of central serotoninergic neurotransmission can reduce the susceptibility of the heart to ventricular fibrillation mediated through a decline in sympathetic neural traffic to the heart.

Lehnert, Hendrik↗

Elastic Response of Crimped Collagen Fibrils

A physiologic constitutive expression is presented in algorithmic format for the elastic response of wavy collagen fibrils found in soft connective tissues. The model is based on the observation that crimped fibrils have a three-dimensional structure at the micrometer scale that we approximate as a helical spring. The symmetry of this waveform allows the force/displacement relationship derived from Castigliano's theorem to be solved in closed form. Model predictions are in good agreement with experimental observations for mitral-valve chordae tendineae

Freed, Alan D.↗

Elastic model for crimped collagen fibrils

A physiologic constitutive expression is presented in algorithmic format for the nonlinear elastic response of wavy collagen fibrils found in soft connective tissues. The model is based on the observation that crimped fibrils in a fascicle have a three-dimensional structure at the micron scale that we approximate as a helical spring. The symmetry of this wave form allows the force/displacement relationship derived from Castigliano's theorem to be solved in closed form: all integrals become analytic. Model predictions are in good agreement with experimental observations for mitral-valve chordae tendinece.

Evaluation Studies↗