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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 19 records

MOSAIC: a joint modeling methodology for combined circadian and non-circadian analysis of multi-omics data

Abstract Motivation Circadian rhythms are approximately 24-h endogenous cycles that control many biological functions. To identify these rhythms, biological samples are taken over circadian time and analyzed using a single omics type, such as transcriptomics or proteomics. By comparing data from these single omics approaches, it has been shown that transcriptional rhythms are not necessarily conserved at the protein level, implying extensive circadian post-transcriptional regulation. However, as proteomics methods are known to be noisier than transcriptomic methods, this suggests that previously identified arrhythmic proteins with rhythmic transcripts could have been missed due to noise and may not be due to post-transcriptional regulation. Results To determine if one can use information from less-noisy transcriptomic data to inform rhythms in more-noisy proteomic data, and thus more accurately identify rhythms in the proteome, we have created the Multi-Omics Selection with Amplitude Independent Criteria (MOSAIC) application. MOSAIC combines model selection and joint modeling of multiple omics types to recover significant circadian and non-circadian trends. Using both synthetic data and proteomic data from Neurospora crassa, we showed that MOSAIC accurately recovers circadian rhythms at higher rates in not only the proteome but the transcriptome as well, outperforming existing methods for rhythm identification. In addition, by quantifying non-circadian trends in addition to circadian trends in data, our methodology allowed for the recognition of the diversity of circadian regulation as compared to non-circadian regulation. Availability and implementation MOSAIC’s full interface is available at https://github.com/delosh653/MOSAIC. An R package for this functionality, mosaic.find, can be downloaded at https://CRAN.R-project.org/package=mosaic.find. Supplementary information Supplementary data are available at Bioinformatics online.

De los Santos, Hannah↗

Joint Modeling of Access Mode and Parking Choice of Air Travelers Using Revealed Preference Data

Airport ground access mode choice is distinct from everyday mode choice decisions, necessitating context-specific choice model estimation. Understanding airport ground access mode choice decisions is not only important for developing infrastructure planning strategies, but also for assessing the impacts of emerging modes on airport revenues, particularly from parking. However, parking choice is an often-overlooked dimension in airport ground access choice modeling. This paper addresses this gap through the development of a joint model of airport access mode and parking option choice using a passenger survey conducted at Dallas-Fort Worth (DFW) International Airport in 2015. Compared with a traditional conditional logit model that does not consider parking options available at DFW airport, the joint model of mode and parking decisions was found to generate more realistic values of travel time and was shown to have better predictive performance, both of which are critical for obtaining better airport parking revenue estimates and identifying traveler cohorts who may respond more strongly to potential policies targeting curb congestion and parking demand.

33 ADVANCED PROPULSION SYSTEMS↗

Joint modelling of astrophysical systematics for cosmology with LSST cosmic shear

ABSTRACT We present a novel framework for jointly modelling the weak lensing source galaxy redshift distribution and the intrinsic alignment (IA) of galaxies through a shared luminosity function (LF). In the context of a Rubin Observatory’s Legacy Survey of Space and Time (LSST) Year 1 and Year 10 cosmic shear analysis, we show that our novel approach produces cosmological parameter constraints which are comparable to standard methods, while offering more physical insight into IA and selection effects. We clarify the relationship between individual parameters of a Schechter LF and the redshift distribution of a magnitude-limited sample, showing the consequences of marginalizing over these parameters when modelling IAs in standard cosmic shear analyses. We explore the impact of the shape of the LF on the cosmic shear data vector, and we outline the potential of this method to naturally model selection functions in redshift distribution estimation. Although this work focuses on LSST cosmic shear, the proposed joint modelling framework is broadly applicable to weak lensing surveys.

Šarčević, Nikolina (ORCID:0000000173016415)↗

Interdependence in active mobility adoption: Joint modeling and motivational spillover in walking, cycling and bike-sharing

Active mobility offers an array of physical, emotional, and social well-being benefits. However, with the proliferation of the sharing economy, new nonmotorized means of transport are entering the fold, complementing some existing mobility options while competing with others. The purpose of this research study is to investigate the adoption of three active travel modes—namely walking, cycling, and bikesharing—in a joint modeling framework. Here, the analysis is based on an adaptation of the stages of change framework, which originates from the health behavior sciences. Multivariate ordered probit modeling drawing on U.S. survey data provides well-needed insights into individuals’ preparedness to adopt multiple active modes as a function of personal, neighborhood, and psychosocial factors. The research suggests three important findings. (1) The joint model structure confirms interdependence among different active mobility choices. The strongest complementarity is found for walking and cycling adoption. (2) Each mode has a distinctive adoption path with either three or four separate stages. We discuss the implications of derived stage-thresholds and plot adoption contours for selected scenarios. (3) Psychological and neighborhood variables generate more coupling among active modes than individual and household factors. Specifically, identifying strongly with active mobility aspirations, experiences with multimodal travel, possessing better navigational skills, along with supportive local community norms are the factors that appear to drive the joint adoption decisions. This study contributes to the understanding of how decisions within the same functional domain are related and help to design policies that promote active mobility by identifying positive spillovers and joint determinants.

42 ENGINEERING↗

Out of Plane Stresses Using a Beam-Based Elastic Foundation Bonded Joint Model

Efficient, semi-analytical models of bonded joints are utilized for initial joint design and sizing due to their convenience and speed. Many of these models are based on beam and plate theories, which are most applicable when in-plane stresses/strains dominate. While this can be a sensible assumption for obtaining the deformations of the joint, out of plane (transverse) stresses are often of critical importance for failure in bonded joints composed of fiber reinforced composite materials. Since through-thickness strains are neglected in these semi-analytical theories, the present study shows a method to back-calculate the out of plane stresses based on stress balance equations, which use the in-plane stresses and displacements that have already been obtained. The method was implemented within the Joint Element Designer (JED) software, and verification and validation examples have been shown. As is typical for these types of models, corner stress singularities are not captured by the JED model, but the general trends of the stress and deformation fields agreed with a higher fidelity finite element model. As such, this method for obtaining out of plane stresses, when coupled with the JED code, is very useful for the complete stress analysis of bonded composite joints.

composites↗

Load distributions in photoeleastic bolted-joint models

An attempt is made to study the stresses in multiple-bolt connectors, focusing on the stress distribution in a two-pin connector, the two pins being in line and in parallel with the direction of the applied load. The photoelastic modeling approach with two-dimensional transmission photoelasticity is used. The joint models and model fringe patterns are discussed, with special attention given to the existence of a photoelastic isotropic point and to the separation of stresses.

Hyer, M. W.↗

Joint Modeling of Quasar Variability and Accretion Disk Reprocessing Using Latent Stochastic Differential Equations

Quasars are bright active galactic nuclei powered by the accretion of matter around supermassive black holes at the center of galaxies. Their stochastic brightness variability depends on the physical properties of the accretion disk and black hole. The upcoming Rubin Observatory Legacy Survey of Space and Time (LSST) is expected to observe tens of millions of quasars, so there is a need for efficient techniques like machine learning that can handle the large volume of data. Quasar variability is believed to be driven by an X-ray corona, which is reprocessed by the accretion disk and emitted as UV/optical variability. We are the first to introduce an auto-differentiable simulation of the accretion disk and reprocessing. We use the simulation as a direct component of our neural network to jointly model the driving variability and reprocessing, trained with supervised learning on simulated LSST-like 10 yr quasar light curves. We encode the light curves using a transformer encoder, and the driving variability is reconstructed using latent stochastic differential equations, a physically motivated generative deep learning method that can model continuous-time stochastic dynamics. By embedding the physical processes of the driving signal and reprocessing into our network, we achieve a model that is more robust and interpretable. We demonstrate that our model outperforms a Gaussian process regression baseline and can infer accretion disk parameters and time delays between wave bands, even for out-of-distribution driving signals. Our approach provides a powerful framework that can be adapted to solve other inverse problems in multivariate time series.

Fagin, Joshua [City Univ. of New York (CUNY), NY (↗

A Comparative Study of Joint Modeling Methods and Analysis of Fasteners [Slides]

Motivation: Crucial aspect of mechanical design is joining methodology of parts. Ability to analyze joint and fasteners in system for structural integrity is fundamental. Different modeling representations of fasteners include spring, beam, and solid elements. Various methods compared for linear system to decide method appropriate for design study. New method for modeling fastener joint is explored from full system perspective. Analysis results match well with published experimental data for new method.

42 ENGINEERING↗

Joint modeling of water and energy for resilience and flexibility

This white paper addresses the intersection of energy and water resources for potable water, considering energy-for-water through joint systems modeling. Specifically, we focus on the opportunities to promote joint resilience in water and power systems through coupled modeling to inform decision-makers.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

A simple nonlinear joint model

Hertzian contact theory is applied to a butt joint with specially mismatched bearing surfaces to devise a simple mathematical model of nonlinear axial force-displacement behavior in jointed members. Normalized tangent stiffness-force plots, for several values of a joint imperfection parameter, are presented for the sample case of solid structural members of circular section. The results illustrate the potential problem of high joint compliance at low axial-force levels, as well as the generally desirable stiffening and linearizing effects of preload. A nonlinear oscillator problem based on the static model is also formulated and solved to illustrate the effect of amplitude on natural frequency. As expected, natural frequency is low when amplitude is small. The results call attention to the important roles that tight tolerances and preload are expected to play in the design and fabrication of deployable and erectable truss-type space structures.

Fichter, W. B.↗

Joint Modeling of Wind Speed and Wind Direction Through a Conditional Approach

Atmospheric near surface wind speed and wind direction play an important role in many applications, ranging from air quality modeling, building design, wind turbine placement to climate change research. It is therefore crucial to accurately estimate the joint probability distribution of wind speed and direction. In this work, we develop a conditional approach to model these two variables, where the joint distribution is decomposed into the product of the marginal distribution of wind direction and the conditional distribution of wind speed given wind direction. To accommodate the circular nature of wind direction, a von Mises mixture model is used; the conditional wind speed distribution is modeled as a directional dependent Weibull distribution via a two-stage estimation procedure, consisting of a directional binned Weibull parameter estimation, followed by a harmonic regression to estimate the dependence of the Weibull parameters on wind direction. A Monte Carlo simulation study indicates that our method outperforms two other approaches in estimation efficiency: one that utilizes periodic spline quantile regression and another that generates data from the commonly used Abe-Ley distribution for cylindrical data. We illustrate our method by using the output from a regional climate model to investigate how the joint distribution of wind speed and direction may change under some future climate scenarios. Our method indicates significant changes in the variation of wind speed with respect to some directions.

17 WIND ENERGY↗

Economics of technological change - A joint model for the aircraft and airline industries

The principal focus of this econometric model is on the process of technological change in the U.S. aircraft manufacturing and airline industries. The problem of predicting the rate of introduction of current technology aircraft into an airline's fleet during the period of research, development, and construction for new technology aircraft arises in planning aeronautical research investments. The approach in this model is a statistical one. It attempts to identify major factors that influence transport aircraft manufacturers and airlines, and to correlate them with the patterns of delivery of new aircraft to the domestic trunk carriers. The functional form of the model has been derived from several earlier econometric models on the economics of innovation, acquisition, and technological change.

Kneafsey, J. T.↗