Performance comparison of Malvern instruments laser diffraction drop size analyzer

Abstract

The performance of ten laser diffraction particle sizing instruments (Malvern models 2200 and 2600) has been evaluated using a synthetic particle size reference standard in a round-robin test at nine independent laboratories. A calibration reticle consisting of a two-dimensional array of opaque, circular particle images photoetched in chrome thin film deposited on a glass substrate was used as the reference. Mean diameters (e.g., D32) for the reticle measured by the ten unmodified instruments varied by 27 percent. In contrast, data from six instruments with individually calibrated photodetector correction factors demonstrated much better agreement and were within 2.6 percent of the actual reticle properties.