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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 127 records · Page 7

Enhanced Surgical Decision-Making Tools in Breast Cancer: Predicting 2-Year Postoperative Physical, Sexual, and Psychosocial Well-Being following Mastectomy and Breast Reconstruction (INSPiRED 004)

Background: We sought to predict clinically meaningful changes in physical, sexual, and psychosocial well-being for women undergoing cancer-related mastectomy and breast reconstruction 2 years after surgery using machine learning (ML) algorithms trained on clinical and patient-reported outcomes data. Patients and Methods: We used data from women undergoing mastectomy and reconstruction at 11 study sites in North America to develop three distinct ML models. We used data of ten sites to predict clinically meaningful improvement or worsening by comparing pre-surgical scores with 2 year follow-up data measured by validated Breast-Q domains. We employed ten-fold cross-validation to train and test the algorithms, and then externally validated them using the 11th site’s data. We considered area-under-the-receiver-operating-characteristics-curve (AUC) as the primary metric to evaluate performance. Results: Overall, between 1454 and 1538 patients completed 2 year follow-up with data for physical, sexual, and psychosocial well-being. In the hold-out validation set, our ML algorithms were able to predict clinically significant changes in physical well-being (chest and upper body) (worsened: AUC range 0.69–0.70; improved: AUC range 0.81–0.82), sexual well-being (worsened: AUC range 0.76–0.77; improved: AUC range 0.74–0.76), and psychosocial well-being (worsened: AUC range 0.64–0.66; improved: AUC range 0.66–0.66). Baseline patient-reported outcome (PRO) variables showed the largest influence on model predictions. Conclusions: Machine learning can predict long-term individual PROs of patients undergoing postmastectomy breast reconstruction with acceptable accuracy. This may better help patients and clinicians make informed decisions regarding expected long-term effect of treatment, facilitate patient-centered care, and ultimately improve postoperative health-related quality of life.

60 APPLIED LIFE SCIENCES↗

Feasibility and preliminary efficacy for morning bright light therapy to improve sleep and plasma biomarkers in US Veterans with TBI. A prospective, open-label, single-arm trial

Mild traumatic brain injury (TBI) is associated with persistent sleep-wake dysfunction, including insomnia and circadian rhythm disruption, which can exacerbate functional outcomes including mood, pain, and quality of life. Present therapies to treat sleep-wake disturbances in those with TBI (e.g., cognitive behavioral therapy for insomnia) are limited by marginal efficacy, poor patient acceptability, and/or high patient/provider burden. Thus, this study aimed to assess the feasibility and preliminary efficacy of morning bright light therapy, to improve sleep in Veterans with TBI (NCT03578003). Thirty-three Veterans with history of TBI were prospectively enrolled in a single-arm, open-label intervention using a lightbox (~10,000 lux at the eye) for 60-minutes every morning for 4-weeks. Pre- and post-intervention outcomes included questionnaires related to sleep, mood, TBI, post-traumatic stress disorder (PTSD), and pain; wrist actigraphy as a proxy for objective sleep; and blood-based biomarkers related to TBI/sleep. The protocol was rated favorably by ~75% of participants, with adherence to the lightbox and actigraphy being ~87% and 97%, respectively. Post-intervention improvements were observed in self-reported symptoms related to insomnia, mood, and pain; actigraphy-derived measures of sleep; and blood-based biomarkers related to peripheral inflammatory balance. The severity of comorbid PTSD was a significant positive predictor of response to treatment. Morning bright light therapy is a feasible and acceptable intervention that shows preliminary efficacy to treat disrupted sleep in Veterans with TBI. A full-scale randomized, placebo-controlled study with longitudinal follow-up is warranted to assess the efficacy of morning bright light therapy to improve sleep, biomarkers, and other TBI related symptoms.

60 APPLIED LIFE SCIENCES↗

Ameliorating Global Challenges: Globalization, Geopolitics, Basic & Applied Research, and Research Security

We are confronted with a myriad of global challenges, from extreme weather events, occurring at higher frequencies than at any point in history, to pollution, food insecurity, clean water shortages, and fundamentally limited natural resources and materials. The largest number of people inhabit our planet today and enjoy the highest standard of living - though not equally distributed across the world - compared to any prior moment in history. To sustain this quality of life, we are largely reliant on fossil fuel sources, which are responsible for more greenhouse gas emissions by weight each day than the collective weight of all humans that inhabit the planet. Ameliorating these global challenges will require elements of solutions that include advances in basic and applied research, innovative global engineering, materials discovery, new technologies, manufacturing at scale, resilient and adaptable infrastructure, carbon-free energy sources and storage technologies, and new supply chain networks and markets. Success will require constructive collaborative efforts between researchers in countries located in every continent of this planet. For any of these goals to be realized in a timely fashion, geopolitical leaders must become better educated about this existential challenge and incentivized to act.

applied research↗

From Bricks to Clicks: Mapping the White Space in Building Innovation

It is a critical national imperative to transform the buildings sector, yet innovation is impeded by deployment failures that leave promising technologies stranded. Conventional market reports and techno-economic analysis provide an insufficient understanding of markets and resource allocation for emerging building technologies. They omit crucial commercialization factors such as ecosystem maturity and adoption friction, where the coordinated participation of a network of suppliers, contractors, financiers, regulators, and integrators is required to scale solutions. This study addresses these gaps by introducing an evaluation framework grounded in front-line data from six years of the DOE's IMPEL incubator, comprising experience from 300 building-sector innovators and the adjacent, complex ecosystem. Our methodology synthesizes top-down market analysis with bottom-up, practitioner-level data across five megatrends: (M1) Affordable materials and industrialized construction; (M2) Healthy and efficient mechanical systems; (M3) Intelligent building operations; (M4) Buildings as grid assets; and (M5) High-density power and cooling for data centers and therein identify twelve "white space" technology opportunities. Next, we develop a multi-criteria scoring rubric to rank these opportunities based on parameters, i.e., Affordability, Quality of Life, Reliability, and Security, yielding composite ‘Demand’ and ‘Maturity’ indices. Our results indicate that the most significant white spaces may not be incremental products but a new class of ‘Ecosystem Enablers’, such as logistics platforms, orchestration layers, and automated compliance software that solve structural deployment gaps. This paper summarizes this transparent, evidence-based, practitioner-informed evaluation framework for policymakers and investors to re-evaluate policy and resource allocation and unlock scalable market transformation.

Singh, Reshma↗

Supply Chain Sustainability Analysis of Renewable Hydrocarbon Fuels via Indirect Liquefaction, Ex Situ Catalytic Fast Pyrolysis, Hydrothermal Liquefaction, Combined Algal Processing, and Biochemical Conversion: Update of the 2019 State-of-Technology Cases

This technical report describes the supply chain sustainability analysis (SCSAs) for the production of renewable hydrocarbon transportation fuels via a range of conversion technologies: (1) renewable high octane gasoline (HOG) via indirect liquefaction (IDL) of woody lignocellulosic biomass (note that the IDL pathway in this SCSA represents the syngas conversion design in the 2019 SOT); (2) renewable gasoline (RG) and diesel (RD) blendstocks via ex situ catalytic fast pyrolysis of woody lignocellulosic biomass; (3) RD via hydrothermal liquefaction (HTL) of wet sludge from a wastewater treatment plant; (4) renewable hydrocarbon fuels via biochemical conversion of herbaceous lignocellulosic biomass; (5) renewable diesel via HTL of a blend of algae and woody biomass; and (6) renewable diesel via combined algae processing (CAP). This technical report focuses on the environmental performance of these six biofuel production pathways in their 2019 SOT cases. The results of these renewable hydrocarbon fuel pathways in these SCSA analyses update those for the respective 2018 SOT cases. They also provide an opportunity to examine the impact of technology improvements in both biomass feedstock production and biofuel production that have been achieved in 2019 SOTs on the sustainability performance of these renewable transportation fuels, and they reflect updates to Argonne National Laboratory’s Greenhouse gases, Regulated Emissions, and Energy use in Transportation (GREET®) model, which was released in October 2019. These GREET updates include the production of natural gas, electricity, and petroleum-based fuels that can influence biofuels’ supply chain greenhouse gas (GHG) (CO₂, CH₄, and N₂O) emissions, water consumption, and air pollutant emissions. GHG emissions, water consumption, and nitrogen oxides (NO x ) emissions are the main sustainability metrics assessed in this analysis. In this analysis, we define water consumption as the amount of water withdrawn from a freshwater source that is not returned (or returnable) to a freshwater source at the same level of quality. Life-cycle fossil energy consumption and net energy balance, which is the life-cycle fossil energy consumption deducted from the renewable biofuel energy produced, are also assessed.

09 BIOMASS FUELS↗

SMART Mobility. Urban Science Capstone Report

The U.S. Department of Energy’s Systems and Modeling for Accelerated Research in Transportation (SMART) Mobility Consortium is a multiyear, multi-laboratory collaborative, managed by the Energy Efficient Mobility Systems Program of the Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office, dedicated to further understanding the energy implications and opportunities of advanced mobility technologies and services. The Urban Science (US) Pillar focuses on maximum-mobility and minimum-energy opportunities associated with emerging transportation and transportation-related technologies specifically within the urban context. Such technologies, often referred to as automated, connected, efficient (or electrified), and shared (ACES), have the potential to greatly improve mobility and related quality of life in urban areas. Although all the SMART Mobility research pillars share some commonalities, Urban Science strives to model, analyze, and gain insights from the perspective of human settlements (the “city”) as a living organism. This is especially critical as the United States is one of the most urbanized countries, and as more and more of the global population migrates to urban areas.1 The urban mobility system consists of a complex network that reaches well beyond roads and vehicles and includes significant investments in public transit, private mobility services (such as taxis and transportation network companies, or TNCs), significant parking reserves, and curb management practices, not to mention the abundance of emerging on-demand micromobility services for the movement of people and goods such as e-bikes and scooters, which make the urban space a dynamic laboratory for mobility. Urban spaces also concentrate employment, markets, services, and attractions, which are the destinations for most trips. The concentration of human activities and ensuing density also creates the need and emphasis for space efficiency in urban environments, which is often less of a constraint in suburban or rural contexts. This mixture of transportation and mobility infrastructure and practice, combined with global urbanization trends, make urban spaces a critical focus of research for developing energy-efficient mobility systems (EEMS).

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Battery Electric Bus Deployment Considerations in Developing Countries

Electrifying the transportation sector holds many promises and there are numerous strategies for doing so, including the deployment of battery electric buses (BEBs). BEBs can improve air quality (particularly in urban areas), may help curb greenhouse gas emissions, and can have positive impacts on public health and the quality of life for city inhabitants. This fact sheet steps through the six essential BEB considerations: 1) implementation planning, 2) technology selection, 3) economic impacts, 4) charging infrastructure, 5) operational, and 6) maintenance.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Document Management: A Focused Analysis on the Configuration Management Process at Y-12 National Security Complex

The configuration management process at Y-12 is a crucial process to ensure safe operations and compliance with Department of Energy (DOE) regulations and requirements. This process is evaluated utilizing systems-thinking methodology in order to understand the current operational flow, with the ultimate goal of building an easily understandable, representative model. This model offers insights on key areas of waste and provides a potential solution by modernizing rate limiting steps: a software implementation to update the traditional document management system and make it paperless. Stakeholders of the software implementation are identified in order to define characteristic requirements of an effective product and the anticipated benefit is evaluated. Ultimately, this project is an effort to increase the quality of life for all stakeholders, while improving the capacity, throughput, and effectiveness of a necessary process at Y-12.

42 ENGINEERING↗

Enhancing Reliability of Classified Shipments Between the Nuclear Security Enterprise

The extent of this project, as related to by the Nuclear Security Enterprise (NSE), is related to the current shipping and logistical issues and optimization opportunities between several different NSE sites that are the basis of the enterprise. This current scope is part of every site’s, described as Design Agency (DA) and Production Agency (PA), normal operation to meet the needs and mission of the National Nuclear Security Administration (NNSA). The NSE has a broad mission scope encompassing several differing DA and PA sites to meet the NNSA’s mission. These sites require frequent interaction and shipments of material and items between one another in order to meet the mission needs of the enterprise. Currently, there is no methodology that integrates schedules, standards, orders, processes, and best practices to optimize transfers between the differing sites. A centralized location and standard shipping process will optimize and improve the systems behavior, reducing lag time and increasing throughput at sites today. Ultimately this project proposes a central logistical platform, tiered escalation process, and standardized shipping forms to reduce taxpayer costs to meet the NSE’s mission more efficiently. This increase in processing logistics and process accuracy of shipments will save the NSE, not only from a monetary value, but it will reduce the frustrations of individuals working these outdated and over processed systems to improve their quality of life.

98 NUCLEAR DISARMAMENT, SAFEGUARDS, AND PHYSICAL P↗

Supply Chain Sustainability Analysis of Renewable Hydrocarbon Fuels via Indirect Liquefaction, Ex Situ Catalytic Fast Pyrolysis, Hydrothermal Liquefaction, Combined Algal Processing, and Biochemical Conversion: Update of the 2020 State-of-Technology Cases

This technical report describes the SCSAs for the production of renewable hydrocarbon transportation fuels via a range of conversion technologies in the 2020 SOTs: (1) renewable high octane gasoline (HOG) via indirect liquefaction (IDL) of woody lignocellulosic biomass (note that the IDL pathway in this SCSA represents the syngas conversion design); (2) renewable gasoline (RG) and diesel (RD) blendstocks via ex situ catalytic fast pyrolysis of woody lignocellulosic biomass; (3) RD via hydrothermal liquefaction (HTL) of wet sludge from a wastewater treatment plant; (4) renewable hydrocarbon fuels via biochemical conversion of herbaceous lignocellulosic biomass; (5) renewable diesel via HTL of a blend of algae and woody biomass; and (6) renewable diesel via combined algae processing (CAP). This technical report focuses on the environmental performance of these six biofuel production pathways in their 2020 SOT cases. The results of these renewable hydrocarbon fuel pathways in these SCSA analyses update those for the respective 2019 SOT cases. They also provide an opportunity to examine the impact of technology improvements in both biomass feedstock production and biofuel production that have been achieved in 2020 SOTs on the sustainability performance of these renewable transportation fuels. The SCSA results also reflect updates to Argonne National Laboratory’s Greenhouse gases, Regulated Emissions, and Energy use in Technologies (GREET ® ) model, which was released in October 2020. These GREET updates include the production of natural gas, electricity, and petroleum-based fuels that can influence biofuels’ supply chain greenhouse gas (GHG) (CO 2 , CH 4 , and N 2 O) emissions, water consumption, and air pollutant emissions. GHG emissions, water consumption, and nitrogen oxides (NO x ) emissions are the main sustainability metrics assessed in this analysis. In this analysis, we define water consumption as the amount of water withdrawn from a freshwater source that is not returned (or returnable) to a freshwater source at the same level of quality. Life-cycle fossil energy consumption and net energy balance, which is the life-cycle fossil energy consumption deducted from the renewable biofuel energy produced, are also assessed.

09 BIOMASS FUELS↗

Community-Scale Solar Deployment in the Northwest Arctic

NANA Regional Corporation (NRC, or NANA) was formed as an Alaska Native Corporation (ANC) pursuant to the Alaska Native Claims Settlement Act of 1971. Our lands cover 39,000 square miles of the Northwest Arctic region of Alaska. We partner closely with the Northwest Arctic Borough (NAB) and our 11 remote communities on numerous projects and activities, especially around clean energy initiatives that improve quality of life and help to reduce extremely high energy costs experienced by the communities in our region. Collectively, the regional partnership has developed numerous successful solar, wind, biomass, and energy storage, distribution upgrade, and efficiency projects. To further progress, we created the Northwest Arctic Energy Steering Committee to share and replicate these benefits across the region. NANA’s mission is to provide economic opportunities for our more than 13,500 Iñupiat shareholders and to protect and enhance NANA lands.

14 SOLAR ENERGY↗

U.S. Department of Energy’s Industrial Decarbonization Roadmap

The science is clear that significant greenhouse gas (GHG) emissions reductions are needed to moderate the severe impacts of ongoing climate change. Bold action is needed, and the Biden Administration has set goals of 100% carbon pollution-free electricity by 2035 and net-zero GHG emissions by 2050. The U.S. Long-Term Strategy (LTS) presents multiple pathways to a net-zero economy by no later than 2050. Addressing environmental justice and energy equity will be integral to meeting these climate goals. The United States’ overall industrial decarbonization strategy will support the Biden Administration’s Justice40 Initiative, which pledges that at least 40% of overall benefits from federal investments in climate and clean energy will be delivered to disadvantaged communities. The U.S. net-zero GHG 2050 goal, while ambitious, is achievable and will provide important benefits for all Americans in terms of public health, economic growth, reduced conflict from climate-related disasters, and quality of life. While this roadmap focuses on GHG emissions, other pollutant emissions will also need to be addressed as industry decarbonizes. Developing new technologies to reduce GHG emissions is an important opportunity to address other environmental issues and inequities. DOE is currently focusing on energy and environmental justice in complementary programs and initiatives. The U.S. industrial sector is considered a “difficult-to-decarbonize” sector of the energy economy, in part because of the diversity of energy inputs that feed into a heterogenous array of industrial processes and operations. In 2020, the industrial sector accounted for 33% of the nation’s primary energy use and 30% of energy-related carbon dioxide (CO 2 ) emissions.

54 ENVIRONMENTAL SCIENCES↗

Guidance for Integrating Energy Justice and Equity in Building Technology Deployment Programs: Tracking, Reporting, and Maximizing the Flow of Benefits from Building System Technology Deployment Activities to Disadvantaged Communities and Target Sectors

The Federal Justice40 Initiative directs at least 40% of the overall benefits of certain clean energy investments to flow to disadvantaged communities and requires that all federal programs covered by Justice40 consult stakeholders to determine the program benefits, and that the flow of benefits to disadvantaged communities is tracked and reported. Unequal distribution of benefits, in terms of access to clean energy research, design, development, and deployment, can disproportionately benefit or burden certain communities. This can result in higher rates of pollution, negative health effects, and increased energy burdens and insecurities in disadvantaged communities. Programs focused on decarbonizing the built environment can enhance health, quality of life, and economic opportunities for impacted communities. This guidance document, developed by Pacific Northwest National Laboratory and funded by the U.S. Department of Energy’s Building Technologies Office, provides best practices and approaches for incorporating energy justice and equity principles into building technology deployment activities. It provides best practices and recommendations for communicating with and involving disadvantaged communities and target building sectors in program activities, along with methods to monitor and report the distribution of benefits to these sectors. This document lays out a set of strategies, metrics, and best practices that can be implemented over time to apply energy justice and equity approaches, whether the program is just starting out or ongoing. Although this guidance was designed for Building Technologies Office technology deployment programs, the best practices, recommendations, and methods can be valuable to any program concerned with the equitable deployment of clean energy technologies. The goal of this project is to enable the equitable development, deployment, and adoption of clean energy technologies and practices.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Development of Human and Technology Integration Guidance for Work Optimization and Effective Use of Information

Existing nuclear power contributes to roughly 20% of the total electricity generation, and consistently provides the highest capacity factor of any other electricity generating resource in the United States. Despite these advantages, the existing nuclear power plant fleet in the United States has been enduring significant challenges in providing electricity in a cost-competitive manner, which has ultimately threatened the long-term economic viability of these plants. A major contributor to these increased operating and maintenance costs has been the continued reliance of a large workforce who perform their work under an operating model that has largely remained unchanged since the commissioning of these nuclear power plants. Unfortunately, while this operating model has provided safe and reliable electricity, other industries have already began transforming their workforce through the use of advanced digital technology and automation that has reduced their operating and maintenance cost significantly. In order for the United States nuclear industry to remain economically viable, a similar transformation must be considered in which digital technologies and automation capabilities are brought in to support key plant functions across all work functions across plant operation, maintenance, and support. To effectively integrate digital technology and automation in the existing nuclear power plant operating model, a multidisciplinary approach is needed that addresses technological and sociotechnical (i.e., human and technology integration) considerations. This report describes an extension to the human and technology integration methodology, herein referred to as Human Integration and Technology Task Force for Work Management Optimization (HITT), to support the safe, reliable, and efficient use of proposed innovations with the intended users in their intended environment to perform their intended tasks. By effectively incorporating human and technology integration into a plant modernization effort by using HITT, we believe that a utility can significantly improve work performance and overall workforce quality of life. For instance, if HITT is performed to optimize work management, scheduling performance and scope stability can be improved by up to 10%. HITT enables these benefits through developing a rich understanding of the work being performed, the utility’s vision, and the opportunities that provide greatest value to optimize performance through a 10-step process illustrated below as a quick guide. The quick guide contains links in the righthand side of each step that allows for navigation to the detailed section (Section 4) of HITT in this technical report.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Quick Talk: Resilient Communities, Maryland

Groundswell, Inc., in partnership with the Maryland Energy Administration (MEA), Ayika Solutions, the National Renewable Energy Lab (NREL), and the Baltimore Office of Sustainability, is advancing a vision for resilient, community-centered energy systems in Maryland. This effort aligns with Groundswell's commitment to a clean energy economy that equitably benefits all communities, closing gaps in representation, wages, and access to wealth generation, savings, and local jobs within a diverse energy supply chain. Project Vision and Objectives The project emphasizes "energy resilience," defined as a community’s capacity to anticipate, adapt to, and swiftly recover from power disruptions through inclusive planning and technical solutions. The approach centers on Resilience Hubs—designated community facilities equipped to support residents before, during, and after power-related disruptions. These hubs offer emergency resources, coordinate communications, and deliver essential services while reducing carbon emissions, ultimately enhancing residents' quality of life. Additionally, Resilience Hubs foster social connections, support disaster preparedness, and provide spaces for community programming and everyday use. The goals of Resilient Communities Maryland include: Developing a replicable framework for community energy resilience, applicable beyond Maryland. Defining community-led indicators of social impact and resilience. Establishing equitable decision-making processes in project design and implementation. Informing MEA of practical, community-based resilience strategies to shape future state initiatives. Approach Groundswell and its partners prioritize collaborative engagement with local stakeholders, ensuring that solutions are responsive to each community's unique needs. By integrating feedback from residents, local organizations, and government entities, the team has developed a holistic model for resilience that balances immediate benefits, such as improved emergency response, with long-term gains in social equity and environmental sustainability. Key Outcomes This initiative has produced valuable resources and insights, including: A Community Energy Resilience Framework: Designed to guide other communities in establishing energy resilience strategies tailored to their specific needs. Case Studies: Documenting best practices and lessons learned from pilot projects to serve as models for future resilience efforts. Community-Driven Impact Metrics: Highlighting the positive social impacts that resilience initiatives can bring, such as improved social connectedness and local decision-making power. Recommendations for MEA: Offering evidence-based insights to inform policies and funding opportunities that support resilient energy infrastructure in vulnerable communities. Next Steps Groundswell's final report will detail findings, including the potential for scaling resilience hubs across Maryland and other regions, with a focus on equitable access and community-driven outcomes. This project underscores the importance of aligning energy resilience with social equity, reinforcing community agency, and building systems that withstand and recover from future challenges effectively and sustainably.

14 SOLAR ENERGY↗

Cool GTL for the Conversion of Biogas to Jet Fuel

Cool GTL is a new process under development for conversion of biogas from digestors or CO2 +H2 to high quality drop in jet fuel. Cool GTL is designed to be a streamlined simplified low cost process which can be cost effective for small scale biogas applications. Cool GTL has the advantage that it uses a high activity bi-reforming catalyst, in a streamlined electric reformer design, to make the synthesis gas for a high conversion slurry fischer Tropsch process followed by a trailing wax cracking reactor. In this way high quality jet fuel can be directly produced. Recent experimental test data will be presented showing product quality. The life cycle analysis LCA will also be presented as well.

09 BIOMASS FUELS↗

Advanced Intelligent Sensor Development and Demonstration for Future Distribution Systems with High Penetration DERs

The nation’s electric grid is evolving to supply the electricity needed for economic growth, health, and quality of life. As the DOE has pointed out “Old Tools Won’t Solve New Problems” This project conceived, designed, built, and demonstrated a new tool that promises to make the emerging grid dependable at a lower cost. The tool is a smart sensor with the sensitivity and the bandwidth to measure actionable information about grid health that was unmeasurable.

24 POWER TRANSMISSION AND DISTRIBUTION↗